Clinical trials: Sympathectomy
Hypertension, Renal
RENABLATE-II Feasibility Study of Catheter Based Renal Denervation to Treat Resistant Hypertension - 157
This is a prospective, multi-center, non-randomized, feasibility study to assess the safety and effectiveness of renal artery sympathetic denervation using the investigational devices in subjects with resistant hypertension.
- Trial name
- RENABLATE-II (NCT02095691)
- Testing
- Celsius® ThermoCool® Renal Denervation
- Volunteers
- 19 people
- Sponsor
- Biosense Webster, Inc.
Hypertension
ConfidenHT System for Diagnostic Electrical Mapping of Renal Nerves
To evaluate the safety and performance of the ConfidenHT System
- Trial name
- RDN (NCT02777216)
- Testing
- ConfidenHT system
- Where
- 3 sites in Greece, Netherlands
- Volunteers
- 20 people
- Sponsor
- BlueWind Medical
Hypertension
Safety and Efficacy Study of Renal Artery Ablation in Resistant Hypertension Patients
This is a prospective, multicenter, feasibility study on the safety and efficacy of renal denervation in patients with resistant hypertension.
- Trial name
- EnligHTN-I (NCT01438229)
- Testing
- St. Jude Medical renal artery ablation system: RF ablation generator (IBI 1500T11.5) and Renal artery ablation catheter (DS3D001, DS3D002)
- Where
- 4 sites in Australia, Greece
- Volunteers
- 47 people
- Sponsor
- Abbott Medical Devices
Hypertension
Sympathetic Mapping/ Ablation of Renal Nerves Trial
To evaluate the safety and efficacy of targeted renal sympathetic denervation using SyMapCath I® and SYMPIONEER S1® Stimulator/ Generator in patients with essential hypertension for at least 6 months of the disease history and…
- Trial name
- SMART (NCT02761811)
- Testing
- SyMapCath I™ catheter and SYMPIONEER S1™ Stimulator/Generator
- Where
- 15 sites in China
- Volunteers
- 220 people
- Sponsor
- SyMap Medical (Suzhou), Ltd.
Hypertension, Uncontrolled Hypertension
A Study of Non-Vascular Renal Denervation Using the Verve Medical Phoenix ™ System
The aim of the study is to assess the safety and effectiveness of a novel device for renal denervation to lower blood pressure in people with uncontrolled hypertension.
- Trial name
- TUSK (NCT05440513)
- Testing
- Renal Pelvic Denervation (bilateral)
- Where
- 2 sites in Georgia
- Volunteers
- 20 people
- Sponsor
- Verve Medical, Inc
Diabetes, Endocrine, Nutritional and Metabolic Diseases (E00-E89)
COMPLEMENT Study- A First in Human Study of Metabolic Neuromodulation Therapy
The purpose of this research study is to collect information about a new treatment for Type 2 Diabetes Mellitus (T2DM), using a medical device called the Metabolic Neuromodulation System which is intended to help regulate blood…
- Trial name
- NCT02278068
- Testing
- Metabolic Neuromodulation System (MNS)
- Where
- 6 sites in New Zealand
- Volunteers
- 46 people
- Sponsor
- Metavention
Metabolic Syndrome
Renal Sympathetic Denervation in Metabolic Syndrome (Metabolic Syndrome Study)
The purpose of this clinical investigation is to determine the effects of renal sympathetic denervation on insulin resistance and muscle sympathetic nerve activity in patients with metabolic syndrome.
- Trial name
- NCT01911078
- Testing
- Renal Denervation, EnligHTN™ Renal Denervation System.
- Where
- Greece
- Volunteers
- 20 people
- Sponsor
- Abbott Medical Devices
Resistant Hypertension
Renal Sympathetic Denervation by Iberis System in Patients With Uncontrolled Hypertension - Iberis-HTN Registry
The purpose of this study is to document safety and efficacy of renal sympathetic denervation treatment in subjects with uncontrolled hypertension by using Iberis renal denervation system.
- Trial name
- Iberis (NCT02295683)
- Testing
- Renal Denervation
- Where
- 2 sites in Serbia, Spain
- Volunteers
- 18 people
- Sponsor
- Terumo Europe N.V.
Resistant Hypertension, Uncontrolled Hypertension
Rapid Renal Sympathetic Denervation for Resistant Hypertension II
This is a global, multi-center, prospective, randomized, controlled study of the safety and effectiveness of renal denervation with the OneShot Renal Denervation System in patients with uncontrolled hypertension.
- Conditions
- Resistant Hypertension, Uncontrolled Hypertension, Renal Artery Ablation
- Trial name
- RAPID II (NCT01939392)
- Testing
- Renal Denervation (OneShot™ Renal Denervation System)
- Where
- Italy
- Sponsor
- Medtronic Endovascular
Uncontrolled Essential Hypertension
Ultrasound Ablation for Essential Hypertension（FIM）
To evaluate the safety and feasibility of disposable intravascular ultrasound ablation catheter and ultrasound ablation instrument in the treatment of essential hypertension.
- Trial name
- NCT05795829
- Testing
- disposable intravascular ultrasound ablation catheter and ultrasound ablation instrument
- Where
- 2 sites in China
- Volunteers
- 10 people
- Sponsor
- Lepu Medical Technology (Beijing) Co., Ltd.
Hypertension, Resistant to Conventional Therapy
Rapid Renal Sympathetic Denervation for Resistant Hypertension
The Covidien OneShot™ ablation system use is to deliver low-level radio frequency (RF) energy through the wall of the renal artery to denervate the human kidney.
- Trial name
- RAPID (NCT01520506)
- Testing
- Covidien OneShot™ System
- Where
- 14 sites in Belgium, Germany and 4 more
- Volunteers
- 50 people
- Sponsor
- Medtronic Endovascular