Clinical trials: Sympathetic Blockade
Anesthesia, Local, Cerebral Vasospasm
Cervical Sympathetic Block in Patients With Cerebral Vasospasm
The purposes of this study are twofold: 1) to assess the effect of a cervical sympathetic block on cerebral blood flow in patients suffering from cerebral vasospasm, after aneurysmal subarachnoid hemorrhage; 2) to evaluate the…
- Conditions
- Anesthesia, Local, Cerebral Vasospasm, Subarachnoid Hemorrhage, Aneurysmal
- Trial name
- NCT05230134
- Testing
- Cervical sympathetic block
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Stanford University
Complex Regional Pain Syndromes, Postherpetic Neuralgia
The Comparison of Sympathetic Blockade of Stellate Ganglion Block and Thoracic Paravertebral Block
The purpose of this study is to investigate the effect of ultrasound-guided thoracic paravertebral block (TPVB) when performing sympathetic block for upper limb pain control.
- Conditions
- Complex Regional Pain Syndromes, Postherpetic Neuralgia, Phantom Limb Pain, Chronic Post Surgical Pain
- Trial name
- NCT04876989
- Testing
- US-SGB, US-TPVB
- Where
- South Korea
- Volunteers
- 69 people
- Sponsor
- Seoul National University
Lumbar Sympathetic Ganglion Block Indication: Neuropathic Pain, CRPS, Hyperhydrosis Etc.
Comparison of Methods of Lumbar Sympathetic Ganglion Block: Distance vs Angle
Lumbar sympathetic ganglion block is used for several neuropathic pain syndromes. The best method of lumbar sympathetic ganglion block is not established.
- Trial name
- NCT01648543
- Testing
- lumbar sympathetic ganglion block
- Where
- South Korea
- Volunteers
- 194 people
- Sponsor
- Yonsei University
Complex Regional Pain Syndrome I of Upper Limb
RCT :Thoracic Sympathetic Block for the Treatment of Complex Regional Pain Syndrome I of the Upper Limb
This is a double-blind randomized controlled trial to evaluate the efficacy of the sympathetic block via thoracic vertebra T3 for the treatment of CRPS I upper limb.
- Trial name
- NCT01612364
- Testing
- thoracic sympathetic block
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- University of Sao Paulo
POTS - Postural Orthostatic Tachycardia Syndrome
RESET-POTS: Multimodal Phenotyping and Stellate Ganglion Block in Postural Orthostatic Tachycardia Syndrome
RESET-POTS is a pilot study for adults with postural orthostatic tachycardia syndrome (POTS), a condition that can cause a rapid increase in heart rate, dizziness, weakness, fatigue and other symptoms when standing.
- Trial name
- RESET-POTS (NCT07837804)
- Testing
- Bilateral Sequential Stellate Ganglion Block
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Medical Centre Ljubljana
Chronic Male Pelvic Pain Syndrome, Prostatitis
Effectiveness of Sympathetic Plexus Block on Male Pelvic Pain (Prostatitis, Prostatodynia)
The purpose of this study is to investigate, by means of a temporary sympathetic nerve block, the involvement of the sympathetic nervous system in Chronic Pelvic Pain Syndrome (CPPS).
- Trial name
- NCT00194636
- Testing
- nerve block
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Washington
Infraclavicular Brachial Plexus Block
Pulse Wave Transit Time After Infraclavicular Block
This prospective observational study aims to evaluate the time-dependent changes in Pulse Wave Transit Time (PWTT) following ultrasound-guided infraclavicular brachial plexus block.
- Trial name
- NCT07669688
- Testing
- Ultrasound-guided infraclavicular brachial plexus block
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Sakarya University
Paroxysmal Sympathetic Hyperactivity
Stellate Ganglion Block Combined With Dexmedetomidine or Subanesthetic Ketamine Infusion for Treatment of Neurostorm.
Neurostorming is a sudden and exaggerated stress response as a result of damage to the brain. With appropriate treatment and time, there is hope for individuals to overcome storming, regain consciousness, and work towards…
- Trial name
- NCT06354673
- Testing
- Stellate ganglion block, Dexmedetomidine, Ketamine
- Where
- Egypt
- Volunteers
- 205 people
- Sponsor
- Zagazig University
Post Acute COVID-19 Syndrome, Long COVID
Dual Sympathetic Blocks for Patients Experiencing Sympathetically-Mediated Symptoms From Long COVID
The main purpose of this study is to gather data and assess changes in patient-reported outcomes with the stellate ganglion blocks as treatment for their sympathetically-mediated long COVID symptoms.
- Conditions
- Post Acute COVID-19 Syndrome, Long COVID, Long Covid19, COVID-19 Recurrent
- Trial name
- DSBLongCOVID (NCT05638620)
- Testing
- stellate ganglion block with 0.5% bupivacaine
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Jonathann Kuo, MD
Pregnancy, Cesarean Section
The Effect of Low-dose Atropine on Sympathetic Blockade in Spinal Cesarean Section Patients
The most common side effect in cesarean section surgeries performed under spinal anesthesia is hypotension, which is seen in over 80% and can cause significant morbidity for the mother and fetus.
- Conditions
- Pregnancy, Cesarean Section, Anesthesia, Spinal
- Trial name
- NCT05892913
- Testing
- Slow dose preemptive Atropine, Ephedrine
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Abant Izzet Baysal University
Chronic Heart Failure
Effects of Cardiac Sympathetic Blockade in Patients With Chronic Heart Failure
Although current pharmaceutical therapies have improved the survival rate in heart failure it remains a fatal disease and is associated with a poor 3-year survival.
- Trial name
- NCT02282618
- Testing
- Cardiac Sympathetic Blockade
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Harbin Medical University
Shoulder Hand Syndrome, Complex Regional Pain Syndromes
Tolerability of Suprascapular and Median Nerve Blocks for the Treatment of Shoulder-hand Syndrome
Shoulder-hand syndrome (SHS) in stroke patients is painful and lowers quality of life. Unfortunately, the cause of SHS is not known, diagnosing SHS can be difficult, and treating it can be hard.
- Trial name
- NCT03291197
- Testing
- Suprascapular and median nerve blocks
- Where
- Canada
- Volunteers
- 5 people
- Sponsor
- Ottawa Hospital Research Institute
Upper Limb Nerve Block
The Study of Regional Hemodynamic Changes After Specific Brachial Plexus Block by Ultrasound Guidance
Phase 1 Sympathetic block leads to vasodilatation and increases in blood flow. However, regional hemodynamic changes of radial and ulnar artery after specific nerve block of brachial plexus remains unclear.
- Trial name
- NCT02139982
- Testing
- specific nerve block, ropivacaine
- Where
- China
- Volunteers
- 110 people
- Sponsor
- Wenzhou Medical University
Vasovagal Syndrome VVS, Cardioinhibitory Carotid Sinus Syndrome CSS
POLish Registry of CArdioneuroablation and CArdioneuromodulation
The multicentre observational study POL-CA involves a wide spectrum of patients with a history of syncopy. The study recruits patients with diagnosed vasovagal syndrome, cardioinhibitory carotid sinus syndrome, symptomatic sinus…
- Conditions
- Vasovagal Syndrome VVS, Cardioinhibitory Carotid Sinus Syndrome CSS, Symptomatic Sinus Bradycardia SB or Atrioventricular Block AV, Postural Orthostatic Tachycardia Syndrome POTS
- Trial name
- POL-CA (NCT07196397)
- Testing
- cardioneuroablation, SN sparing hybrid ablation, Cardiac sympathetic denervation
- Where
- Poland
- Volunteers
- 1,000 people
- Sponsor
- SABAMED Medical Center Ltd.
Hypertension
Efficacy and Safety of Radiofrequency Renal Denervation in Drug Resistant Hypertension
Single-center, single group study of the efficacy and safety of transcatheter renal denervation for treatment of patients with essential hypertension uncontrolled despite combined pharmacotherapy including 3 or more hypotensive…
- Trial name
- NCT01499810
- Testing
- Bilateral radiofrequency sympathetic renal denervation
- Where
- Russia
- Volunteers
- 53 people
- Sponsor
- Tomsk National Research Medical Center of the Russian Academy of Sciences
L L Ischemia
Ultrasongraphy Versus Fluoroscopy in Lumber Sympathetic Block in Chronic Lower Limb Ischemia
The aim of this study is to compare total procedure time and success rate between FL-guided and US-assisted LSGBs in Lower Limb Ischemic patients.
- Trial name
- NCT06073795
- Testing
- sympathetic block
- Volunteers
- 60 people
- Sponsor
- Assiut University
Vasospasm
Safety Study of Cervical Sympathetic Block for Cerebral Vasospasm Following Aneurysmal Subarachnoid Hemorrhage
To evaluate the feasibility of performing a cervical sympathetic block in patients with severe cerebral vasospasm involving the anterior cerebral circulation following aneurysmal SAH.
- Trial name
- NCT00930072
- Testing
- Cervical Sympathetic Block (bupivicaine, clonidine)
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- University of Washington
Spinal Anesthesia
Evaluation of the Recovery of the Sympathetic Block After Spinal Anesthesia by Thermographic Image
Spinal anesthesia is a locoregional perimedullary anesthesia which consists of temporary interruption of nerve transmission within the subarachnoid space.
- Trial name
- THERMOSYMPA (NCT05277220)
- Testing
- Thermal Camera Thermo Malin TC
- Volunteers
- 63 people
- Sponsor
- Central Hospital, Nancy, France
Chronic Pain Requiring Stellate, Thoracic, and Lumbar Sympathetic Ganglia Blockade
Measurement of the Skin Sympathetic Nerve Activity During Stellate, Thoracic, and Lumbar Sympathetic Ganglia Block
Sympathetic nerve activity can be measured transcutaneously in awake patients by computer-based filtering of raw signal obtained via skin leads attached on the chest and the right arm.
- Trial name
- NCT03902860
- Where
- South Korea
- Volunteers
- 32 people
- Sponsor
- Seoul National University Hospital
Neuropathic Pain, Neuropathic Pain Diagnostic Questionnaire (DN4) ≥ 4
Hematological Indices and Sympathetic Block Response in Neuropathic Pain
This prospective observational study aims to evaluate the relationship between hematological inflammatory indices and clinical treatment response in patients with neuropathic pain undergoing sympathetic nerve block procedures as…
- Trial name
- HINSPAIN (NCT07596823)
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Ankara City Hospital Bilkent