Clinical trials: Sympathetic Blockade
Anesthesia, Conduction, Brachial Plexus Blockade
Comparison of Sympathetic Blockade Duration in Brachial Plexus Blocks Performed by Different Methods
This prospective comparative study will evaluate the sympathetic effects of ultrasound-guided infraclavicular versus supraclavicular brachial plexus blocks in adults undergoing upper-extremity surgery.
- Conditions
- Anesthesia, Conduction, Brachial Plexus Blockade, Sympathetic Blockade
- Trial name
- NCT07326436
- Testing
- Supraclavicular brachial plexus block, Infraclavicular brachial plexus block
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Bozyaka Training and Research Hospital
Subarachnoid Hemorrhage, Aneurysmal, Delayed Cerebral Ischemia
Noninvasive CA Monitoring Validation and Autonomic Modulation in Aneurysmal Subarachnoid Hemorrhage
This is a two-component prospective study of adult aneurysmal subarachnoid hemorrhage (aSAH) patients admitted to the Neurosciences Intensive Care Unit (NSICU) at UT Southwestern Medical Center.
- Conditions
- Subarachnoid Hemorrhage, Aneurysmal, Delayed Cerebral Ischemia, Cerebral Vasospasm, Autonomic Nervous System Diseases
- Trial name
- NCT07577739
- Testing
- Right-Sided Cervical Sympathetic Block at C6, Transcutaneous Auricular Vagal Nerve Stimulation (taVNS)
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- University of Texas Southwestern Medical Center
Thoracic; Sympathetic Ganglion, Injury
Thoracic Sympathetic Ganglion Block Inadvertent Spread
This study wants to identify the incidence of inadvertend intercostal or epidural spread of thoracic sympathetic block
- Trial name
- NCT03995576
- Testing
- thoracic sympathetic ganglion block
- Where
- 2 sites in South Korea
- Volunteers
- 53 people
- Sponsor
- Keimyung University Dongsan Medical Center
Encephalomyelitis, Myalgic, Chronic Fatigue Syndrome
Effect of Stellate Ganglion Block on ME/CFS
The goal of this clinical trial is to study the effects of stellate ganglion block (SGB) in participants with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS).
- Conditions
- Encephalomyelitis, Myalgic, Chronic Fatigue Syndrome, Chronic Fatigue Disorder, Chronic Fatigue and Immune Dysfunction Syndrome
- Trial name
- SGB_ME (NCT05664711)
- Testing
- Bupivacaine Injection
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Neuroversion, Inc.
Failed Back Surgery Syndrome (FBSS)
Caudal Epidural With or Without Lumbar Sympathetic Block for Redo Lumbar Surgery
Comparing the analgesic effect of caudal epidural versus combined lumbar sympathetic block with caudal epidural in patients undergoing redo spinal surgery.
- Trial name
- CLEARS (NCT07199816)
- Testing
- Fluoroscopy-Guided Caudal Epidural Block, Combined Lumbar Sympathetic Ganglion Block and Caudal Epidural Block
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- Hebatullah Mohammed Abdelmageed
Cesarean Section Complications, Spinal Anesthesia
Ultrasound Guided Fluid Loading Before Spinal Anesthesia
Perioperative hypotension is a common complication of spinal anesthesia during cesarean sections. The aim of this study was to evaluate the effectiveness of echoguided correction of hypovolemia through crystalloid preloading on…
- Conditions
- Cesarean Section Complications, Spinal Anesthesia, Hypotension, Hypovolemia
- Trial name
- EHCOPRESPA (NCT07108881)
- Testing
- C, T
- Where
- Tunisia
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- University Tunis El Manar
Ventricular Tachycardia
Percutaneous Inferior Cervical Sympathetic Block for Treatment of Refractory Ventricular Tachycardia
The purpose of this research study is to examine the effect of percutaneous inferior cervical sympathetic block on life threatening abnormal heart rhythms called ventricular tachycardia or ventricular fibrillation that can lead…
- Trial name
- NCT04770051
- Testing
- Percutaneous inferior cervical sympathetic block
- Sponsor
- University of Missouri-Columbia
Hypotension
Management Arterial Hypotension During Planned Caesarean Section, Intravenous Ephedrine/Phenylephrine Mixture Versus Intravenous Baby Noradrenaline
Comparison of two practices of obstetrical services between the CHU of Clermont Ferrand and the HFME Lyon-Bron in the management of arterial hypotension during an elective cesarean section
- Trial name
- ARTEMIS (NCT05513066)
- Where
- 2 sites in France
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Arteriovenous Fistula
Regional Anesthesia for Arteriovenous Fistula
Once kidney function goes below 10 to 15 percent of normal, dialysis treatments or a kidney transplant are necessary to sustain life.
- Trial name
- NCT02305992
- Testing
- Axillary Block with 0.5% Ropivicaine, Stellate ganglion block with 0.2% Ropivicaine, Local anesthetic infiltration with 0.25% Bupivicaine
- Where
- Canada
- Sponsor
- McMaster University
Healthy Volunteers, Sympathetic Activity
SPARK Study - Sympathetic Periarterial Radial Block in Healthy Volunteers
The SPARK Study evaluates changes in peripheral sympathetic vasomotor activity following a targeted, ultrasound-guided periarterial sympathetic block of the distal radial artery in healthy volunteers.
- Trial name
- SPARK (NCT07429292)
- Testing
- Lidocaine 2%
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Duke University
Ovarian Cyst
Effects of Adrenergic Drugs on the Fluid Balance During Surgery
The aim this study was to examine to what degree the slow turnover of lactated Ringer's solution during anesthesia and surgery can be prevented by infusing esmolol (a ß1-receptor blocker) or phenylephrine in patients undergoing…
- Trial name
- NCT01431612
- Testing
- Esmolol administration, Phenylephrine infusion, Lactated Ringer´s solution
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Sodertalje Hospital
PTSD
Efficacy of Cervical Sympathetic Blocks for PTSD
Millions of people suffer from anxiety disorders, including posttraumatic stress disorder (PTSD)-a condition that can profoundly disrupt daily life.
- Trial name
- NCT07087015
- Testing
- Cervical sympathetic nerve block, Ropivacaine, Normal Saline
- Volunteers
- 20 people
- Sponsor
- Stanford University
Complex Regional Pain Syndrome, Postherpetic Neuralgia
Comparison of the Efficacy of the Ultrasound With Fluoroscopy in Guidance of Lumbar Sympathetic Block
This study compares the efficacy of the ultrasound with fluoroscope in guidance of lumbar sympathetic block (LSB). The goals of the study are; 1) To show that US-guided LSB results in shorter performance time compared to…
- Conditions
- Complex Regional Pain Syndrome, Postherpetic Neuralgia, Diabetic Polyneuropathy, Peripheral Neuropathy
- Trial name
- NCT02737527
- Testing
- 24G intravenous route for Lumbar Sympathetic Block (LSB):, 15-cm Chiba needle for Lumbar Sympathetic Block (LSB), Ultrasound for Lumbar Sympathetic Block (LSB)
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Seoul National University
Metabolic Syndrome, Obesity
Cortisol and Nutritional Sympathetic Responsiveness
This project will examine whether short-term (over a 12-hour period) pharmacological lowering of the stress hormone 'cortisol' improves the nervous system response to food intake in overweight or obese individuals who have…
- Conditions
- Metabolic Syndrome, Obesity, Insulin Resistance
- Trial name
- NCT01620684
- Testing
- metyrapone
- Where
- Australia
- Volunteers
- 24 people
- Sponsor
- Baker Heart Research Institute
Anesthesia Time
Single Lumen Intubation and Heart-Lung Machine (HLM) Mode Ventilation
In this trial, we aimed to compare anesthetic outcomes of single lumen intubation with Heart-Lung Machine mode ventilation versus double lumen intubation study in endoscopic thoracic sympathetic blockade.
- Trial name
- NCT05791045
- Testing
- single vs double
- Where
- Turkey (Türkiye)
- Volunteers
- 135 people
- Sponsor
- Biruni University
Autonomic Dysfunction
Cervicothoracic Sympathetic Block Evaluation for Post COVID Condition
Post-COVID Condition (PCC) affects roughly 2.1 million Canadians, carrying an annual economic burden of CAD $7.8-50.6 billion. It presents across multiple organ systems with symptoms including fatigue, brain fog, palpitations…
- Trial name
- CeASE (NCT07468604)
- Testing
- 5 mL of 0.25% bupivacaine with epinephrine (1:200,000)
- Where
- 2 sites in Canada
- Volunteers
- 78 people
- Sponsor
- University Health Network, Toronto
Complex Regional Pain Syndromes
Infrared Imaging in Complex Regional Pain Syndrome
This research proposal aims to investigate the potential use of Infrared (FLIR) imaging to monitor the successful achievement of the sympathetic blockade in patients with complex regional pain syndrome (CRPS).
- Trial name
- NCT05693337
- Testing
- Forward Looking Infrared Radar (FLIR) thermal imaging
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Hospital for Special Surgery, New York
Hypertension
Sympathetic Nervous System Modulation in Hypertension
This is a study of patients with high blood pressure who are already treated with an angiotensin converting enzyme inhibitor or receptor blocker and have achieved good or fair blood pressure control.
- Trial name
- NCT00491387
- Testing
- Metoprolol Succinate
- Volunteers
- 24 people
- Sponsor
- University of Cincinnati
Cancer, Malignant Tumors, Abdominal Cancer
Neurolytic Block Techniques In Abdominal Visceral Cancer Pain
The neurolytic blocks of sympathetic chains are commonly used for the treatment of cancer-related pain. This study aims to compare celiac plexus neurolysis and splanchnic nerve neurolysis for the treatment of abdominal visceral…
- Conditions
- Cancer, Malignant Tumors, Abdominal Cancer, Cancer Pain, Visceral Pain
- Trial name
- CONCERN (NCT06978673)
- Testing
- Splanchnic nerve neurolysis - 5 ml of absolute alcohol (100%), Celiac Plexus Neurolysis - 5 ml of absolute alcohol (100%)
- Where
- Brazil
- Volunteers
- 64 people
- Sponsor
- Instituto do Cancer do Estado de São Paulo
Post Mastectomy Pain Syndrome, Chronic Pain Following Surgical Procedure for Cancer
Super-voltage PRF of Stellate Ganglion Versus Super-voltage PRF of T2 T3 Sympathetic Ganglia in Managing PMPS.
The aim of this study is to compare the effectiveness of super-voltage pulsed radiofrequency of stellate ganglion and super-voltage pulsed radiofrequency of T2-T3 sympathetic ganglia in the treatment of postmastectomy pain…
- Trial name
- PMPS PRF (NCT07675096)
- Testing
- Group S : Stellate Ganglion supervoltage pulsed radiofrequency, Group T : T2-T3 chains supervoltage pulsed radiofrequency.
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- National Cancer Institute, Egypt