Clinical trials: Symptom, Behavioral
Behavioral and Psychological Symptoms of Dementia, Dementia
Validation and Reliability of the Turkish Version of the Montreal Cognitive Assessment-Basic (MoCA-B) in Individuals With Low Educational Level
This study aimed to evaluate the validity, reliability, and diagnostic accuracy of the Turkish version of MoCA-B in distinguishing healthy controls, mild cognitive impairment (MCI), and dementia patients within a low-education…
- Conditions
- Behavioral and Psychological Symptoms of Dementia, Dementia, Dementia (Diagnosis), Dementia Alzheimer Type
- Trial name
- MoCA-B Turkish (NCT07630688)
- Where
- Turkey (Türkiye)
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- Antalya Training and Research Hospital
Eating Disorders, Maladaptive Personality Trait
Metacognitive Interpersonal Therapy Across Transdiagnostic Eating Disorders, Including Underweight
The goal of this clinical trial is to assess if Metacognitive Interpersonal Therapy for Eating Disorders (MIT-ED) is effective for treating various forms of Eating Disorders (ED) and reducing dropout rates.
- Conditions
- Eating Disorders, Maladaptive Personality Trait, Personality Disorder, Personality Trait
- Trial name
- NCT06693089
- Testing
- MIT-ED
- Where
- 2 sites in Italy
- Volunteers
- 64 people
- Sponsor
- GLORIA FIORAVANTI
Major Depressive Disorder
Trial of Centanafadine Efficacy and Safety as Monotherapy or as Adjunct to SSRI in Adults With Major Depressive Disorder
This is a phase 2, multicenter, randomized, double-blind, placebo-controlled, parallel-arm trial to assess the efficacy, safety, and tolerability of centanafadine once-daily (QD) extended-release (XR) capsules for the treatment…
- Trial name
- JUNIPER (NCT05536414)
- Testing
- Centanafadine, Escitalopram
- Where
- 62 sites in United States
- Volunteers
- 337 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Behavioral Symptoms, Autistic Disorder
Study of Aripiprazole in the Treatment of Children and Adolescents With Autistic Disorder (AD)
This study will compare the effectiveness (how well the drug works) of aripiprazole with placebo (fixed dose) in reducing serious behavioral problems in children and adolescents with a diagnosis of autistic disorder (AD).
- Trial name
- NCT00337571
- Testing
- Aripiprazole
- Where
- 31 sites in United States
- Volunteers
- 218 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Treatment Resistant Depression
A Study to Assess the Efficacy, Safety and Tolerability of VLS-01 Buccal Film, Compared to Placebo in Patients With Treatment Resistant Depression (ELUMINA)
This Phase 2 study (protocol number VLS-01-203) will determine the efficacy, safety, and tolerability of short-term treatment with a VLS-01 transmucosal buccal film (VLS-01-BU) in patients with treatment resistant Major…
- Trial name
- NCT06524830
- Testing
- VLS-01-203 BU
- Where
- 48 sites in United States, Australia and 2 more
- Volunteers
- 142 people
- Sponsor
- atai Therapeutics, Inc.
Human Immunodeficiency Virus, Alcohol-Related Disorders
Project Khanya: Peer-Delivered Intervention to Improve HIV Medication Adherence and Substance Use in South Africa
The purpose of this study is to evaluate a stepped care behavioral intervention for HIV medication adherence and substance use ("Khanya") integrated into an HIV primary care setting in South Africa.
- Conditions
- Human Immunodeficiency Virus, Alcohol-Related Disorders, Drug Use, Substance Use
- Trial name
- NCT05933226
- Testing
- Khanya
- Where
- South Africa
- Volunteers
- 160 people
- Sponsor
- University of Maryland, College Park
Mild Cognitive Impairment, Dementia
Multi-modal Large Language Model-Empowered Talk Therapy for Older Adults With ADRD
The purpose of this study is to test the usefulness and the effect of Smart Virtual Reminiscence (SVR) therapy intervention on the Behavioral and Psychological Symptoms of Dementia (BPSD) of patients with Alzheimer's Disease and…
- Conditions
- Mild Cognitive Impairment, Dementia, BPSD, BPSD (Behavioral and Psychological Symptoms of Dementia)
- Trial name
- SVR (NCT07499570)
- Testing
- Smart Virtual Reminiscence Therapy, Music Therapy
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Indiana University
Urinary Incontinence, Daytime Wetting
Brain Activity Among Children With Overactive Bladder and Daytime Urinary Incontinence and Healthy Children
The aim of this study is to investigate whether the activity in brain areas controlling the bladder is different among children suffering from Overactive Bladder (OAB) and Daytime Urinary Incontinence (DUI) compared to age- and…
- Conditions
- Urinary Incontinence, Daytime Wetting, Urination Disorders, Urination Involuntary
- Trial name
- NCT05989646
- Testing
- Sacral TENS
- Where
- 4 sites in Denmark
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Aalborg University Hospital
Behavioral Symptoms, Community Health Workers
Health Equity and Rural Education (HERE!) Clinical Trial
The goal of this community-engaged research is two-fold. The first goal is to gather stakeholder feedback to inform a school-based community health worker intervention with youth with poor school attendance and an enhanced usual…
- Conditions
- Behavioral Symptoms, Community Health Workers, Social Determinants of Health, Educational Problems
- Trial name
- HERE (NCT06460116)
- Testing
- School-Based Community Health Worker (SB-CHW) intervention, Enhanced Usual Care (EUC) Methods
- Where
- United States
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Urinary Incontinence, Daytime Wetting
The Voided Urinary, Perineal, and Faecal Microbiota Among Children and Adolescents - the PpUF-study.
The aim of this study is to investigate whether the voided urinary, perineal/preputial, and the fecal microbiota are different between children suffering from Overactive Bladder (OAB) and Daytime Urinary Incontinence (DUI)…
- Conditions
- Urinary Incontinence, Daytime Wetting, Urination Disorders, Urologic Diseases
- Trial name
- NCT07535619
- Where
- 4 sites in Denmark
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Aalborg University Hospital
Suicide Prevention, Suicide
Integrating the Youth Nominated Support Team (YST) With CBT for Black Youth With Acute Suicide Risk: Aim 2b
This is a second pilot study being completed based on lessons learned from the Aim 2a feasibility pilot study (NCT06941311). Following modifications, the investigators are testing the acceptability, feasibility, and preliminary…
- Conditions
- Suicide Prevention, Suicide, Self-Injurious Behavior, Behavioral Symptoms
- Trial name
- NCT07506460
- Testing
- Cognitive Behavioral Therapy for Suicide Prevention (CBT-SP), Youth-Nominated Support Team
- Where
- 2 sites in United States
- Volunteers
- 90 people
- Sponsor
- University of Michigan
Patient Engagement, Behavioral Symptoms
How to Bathe a Person With Dementia? A Bathing Intervention Based on Basale Stimulation® for People With Moderate to Severe Dementia
Brief summary Resisted behaviours that occur during showering of People with Dementia (PwD) cause greater discomfort for caregivers and may occur as a result of embarrassment and shame that the person with dementia may be…
- Trial name
- NCT05353049
- Testing
- Bathing technique based on Basale Stimulation
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- University of Salamanca
Visual Rehabilitation, Visual Impairment, Autism Spectrum Disorder, Developmental Disabilities, Intellectual Disability, Behavioral Symptoms
Evaluation of a Program to Enhance Ophthalmic Compliance in Children and Adolescents With Special Needs
The goal of this clinical trial is to learn about the effects of the structured program incorporating contextual, behavioral, and cognitive strategies to improve compliance of children and adolescents with special needs during…
- Trial name
- NCT06717282
- Testing
- visual rehabilitation for ophthalmic compliance, Using contextual, behavioral, and cognitive-based stragegies to develop training programs
- Where
- Taiwan
- Volunteers
- 20 people
- Sponsor
- National Taiwan University Hospital
Huntington Disease
Home-based TDCS (Transcranial Direct Current Stimulation) for Cognitive and Behavioral Symptoms in Huntington's Disease
The researchers hope to find out effects of transcranial direct current stimulation (tDCS) sessions on the behavioral symptoms of Huntington's Disease.
- Trial name
- NCT06843252
- Testing
- Transcranial direct current stimulation (tDCS)
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Depression
Feasibility of CALM Therapy in Korean Cancer Patients
This feasibility study examined the cultural adaptation and implementation of Managing Cancer and Living Meaningfully (CALM) therapy for advanced cancer patients in Korea.
- Trial name
- CALM_Korea (NCT07355153)
- Testing
- Managing Cancer and Living Meaningfully (CALM)
- Where
- 2 sites in South Korea
- Volunteers
- 90 people
- Sponsor
- Kyungpook National University Hospital
Dementia
User-Led Meaningful Activity and Early-Stage Dementia
Neuropsychiatric symptoms are the most difficult, distressing, and burdensome aspects of dementia care and a catalyst for long-term care placement.
- Trial name
- NCT05159869
- Testing
- User-Led Meaningful Activity Plan
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- Johns Hopkins University
Diabetes Mellitus Type 2, Continuous Glucose Measurement
Effectiveness of Individualized Automatic Coaching Message for Glycemic Management and Depressive Symptom
This is a 12-week, single-center, randomized, prospective, confirmatory study of effectiveness of the individualized automatic coaching messages for glycemic management based on continuous glucose monitoring and depressive…
- Conditions
- Diabetes Mellitus Type 2, Continuous Glucose Measurement, Depressive Symptom
- Trial name
- NCT06769906
- Testing
- Individualized automatic coaching message for glycemic management and depressive symptom
- Where
- South Korea
- Volunteers
- 46 people
- Sponsor
- Samsung Medical Center
TSC, Behavioral Symptoms
Regulating Together in Tuberous Sclerosis Complex
The purpose of this study is to use a program called Regulating Together (RT), a remote, non-pharmacologic intervention to treat symptoms of emotion dysregulation in children and adolescents with Tuberous Sclerosis Complex (TSC)…
- Trial name
- RT (NCT06105736)
- Testing
- Behavioral Intervention in a small group platform
- Where
- 2 sites in United States
- Volunteers
- 105 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Depression
Implementation Strategies for Task-Shifting Depression Care Depression Care in Vietnam
The study is a Hybrid Implementation-Effectiveness study that will primarily test the implementation strategies on provider adoption and implementation quality in three Vietnam provinces.
- Trial name
- NCT04491045
- Testing
- Workshop Training on Multicomponent Collaborative Care for Depression, Supervision, Community-Engaged Learning Collaborative
- Where
- 2 sites in Vietnam
- Volunteers
- 1,382 people
- Sponsor
- City University of New York, School of Public Health
Breast Cancer, Symptom, Behavioral
YES Study - Newly Diagnosed/Metastatic Intervention
This research study is being done to monitor common symptoms and behavior, and to provide supportive care information and peer support, as well as research opportunities for young women ages of 18-39 years old who have been…
- Trial name
- YES (NCT04379414)
- Testing
- YES portal
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Dana-Farber Cancer Institute