Clinical trials: Symptom
Breast Cancer, Chronic Pain
Effect of Chemotherapy on Pain Sensitivity and Patient-reported Symptoms
Many breast cancer survivors report chronic pain that develops or worsens following chemotherapy. The impact of chemotherapy on the development of chronic pain is uncertain.
- Trial name
- NCT01983982
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Michigan
Diabetes Mellitus, Type 2, Metabolic Associated Fatty Liver Disease
Correlation Between Serum Nociceptin and Sympathetic Nerve Activity in Diabetic Patients With MAFLD
This observational study aims to investigate the relationship between serum nociceptin levels and sympathetic nervous system activity in patients with both type 2 diabetes mellitus (T2DM) and metabolic associated fatty liver…
- Trial name
- NCT07663682
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Second Hospital of Shanxi Medical University
Diabetes Mellitus, Type 2
Feasibility Study on the Impact of Economic Incentives to Improve the Management of Type 2 Diabetes Mellitus
This feasibility study aims to compare the implementation process of three different interventions that use economic incentives to promote lifestyle behavioral changes in patients with type 2 diabetes mellitus, and to identify…
- Trial name
- REDEEM-Pilot (NCT02891382)
- Testing
- Diabetes education, Goal setting, Companion Support
- Where
- Peru
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Universidad Peruana Cayetano Heredia
Epilepsy
Self Acupressure on Fatigue and Sleep Quality in Epilepsy Patients
The aim of this study is to examine the effect of Self-acupressure application on fatigue and sleep quality in epilepsy patients.
- Trial name
- NCT05552924
- Testing
- Self-Acupressure
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Noninvasive Ventilation, COPD
Effect of Web-Based Adaptation and Insomnia Severity in Individuals Using Noninvasive Ventilators at Home
Home use of the NIV device, which is used to manage respiratory failure, one of the most disturbing symptoms due to COPD, will continue to increase.
- Trial name
- NCT06343324
- Testing
- Web-based education
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- KTO Karatay University
Overweight or Obese Breast Cancer Patients
Motivating to Exercise and Diet, and Educating to Healthy Behaviors After Breast Cancer
The primary objective of MEDEA is to compare the effect of a personalised telephone-based health education weight loss program based on motivational coaching, exercise and diet versus a standard health educational program control…
- Trial name
- MEDEA (NCT04304924)
- Testing
- The personalized telephone based intervention
- Where
- France
- Volunteers
- 220 people
- Sponsor
- Gustave Roussy, Cancer Campus, Grand Paris
Total Hip Arthroplasty (THA), Postoperative Pain Management After Total Hip Arthroplasty
MRI-Based Assessment of Local Anesthetic Spread in the PENG Block Compartment
This study uses MRI imaging to evaluate the spread of local anesthetic following the administration of a pericapsular nerve group (PENG) block.
- Trial name
- MRI-PENG (NCT07040423)
- Testing
- PENG Block, Magnetic resonance imaging
- Where
- Italy
- Volunteers
- 6 people
- Sponsor
- Campus Bio-Medico University
Sepsis, Severe, Septic Shock
Metabolic Resuscitation Using Ascorbic Acid, Thiamine, and Glucocorticoids in Sepsis.
This study has been created to compare the addition of intravenous (IV) vitamin C, thiamine, and hydrocortisone to the usual standard of care of sepsis and septic shock.
- Trial name
- ORANGES (NCT03422159)
- Testing
- Ascorbic Acid, Thiamine, Hydrocortisone
- Where
- 2 sites in United States
- Volunteers
- 140 people
- Sponsor
- Community Medical Center, Toms River, NJ
Postmenopause
Use of the Synthetic Hormone CDB-2914 in Treating Symptoms of Menopause
This study will examine the safety and effectiveness of a synthetic hormone, CDB-2914, for treating symptoms of menopause. It will compare the effects of estrogen and CDB-2914 with those of estrogen and progesterone in…
- Trial name
- NCT00009659
- Testing
- CDB 2914
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Autism Spectrum Disorder
Transcranial Photobiomodulation for Reducing Autism Symptoms in Children - Open Label Study (TPBMASDOL)
The hypothesis of the study is that photobiomodulation reduces symptoms of autism. Participants will be children between the ages of 2 and 7, who have been diagnosed with moderate to severe autism.
- Trial name
- NCT06359080
- Testing
- Cognilum TM: Light Treatment Condition
- Where
- 2 sites in United States
- Volunteers
- 25 people
- Sponsor
- JelikaLite LLC
Cochlear Implant Recipients, Hearing Loss, Cochlear
An Investigation to Evaluate Sound Coding Enhancements in Adult Cochlear Implant Recipients
This study will evaluate a range of experimental sound coding strategies that may improve hearing for cochlear implant recipients.
- Trial name
- SONORA-MU (NCT06867380)
- Testing
- Investigational sound coding strategy A, Cochlear default sound coding strategy A, Investigational sound coding strategy B
- Where
- 2 sites in Australia
- Volunteers
- 120 people
- Sponsor
- Cochlear
Chronic Periodontitis
Evaluation of Nano-crystalline Hydroxyapatite Silica Gel in Management of Periodontal Intrabony Defects
A clinical and radiographic evaluation of Nano-crystalline hydroxyapatite silica gel in comparison with open flap debridement for management of periodontal intrabony defects.
- Trial name
- NCT02507596
- Testing
- Nano-crystalline hydroxyapatite silica gel, open flap debridement
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Fibromyalgia, Autonomic Dysfunction
The Effects of Inspiratory Muscle Training Female Patients With Fibromyalgia
Fibromyalgia is a chronic condition characterized by widespread musculoskeletal pain, fatigue, sleep disturbances, and psychological symptoms.
- Trial name
- NCT07261696
- Testing
- Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people
- Sponsor
- Nigde Omer Halisdemir University
Myocardial Infarction, Influenza
The Role of Influenza as a Trigger for Acute Myocardial Infarction: a CALIBER Study
The purpose of this study is to examine the incidence of acute myocardial infarction (MI) occurring after an influenza-like illness using linked primary care and disease registry databases.
- Trial name
- NCT01106196
- Where
- 2 sites in United Kingdom
- Volunteers
- 11,208 people
- Sponsor
- University College, London
Obese
EARLY Assessment of MYOcardial Tissue Characteristics in OBESITY (EARLY-MYO-OBESITY)
EARLY-MYO-OBESITY-CMR is a prospective, three-center, cardiac imaging study to investigate cardiac morphology, function, and tissue phenotypes in a cohort of non-diabetic obese adults, and compare with metabolically healthy…
- Trial name
- NCT05277779
- Testing
- cardiac magnetic resonance(CMR)
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- RenJi Hospital
Morbid Obesity
GlideScope With EGRI Assessment in Obese Patients
BACKGROUND Unpredicted difficult tracheal intubation (DTI) with Macintosh laryngoscopy occurs frequently in obese patients. We investigated the incidence of DTI using the GlideScope® videolaryngoscope (GVL) with an algorithm…
- Trial name
- GLOBE (NCT02188979)
- Where
- Italy
- Volunteers
- 195 people
- Sponsor
- Università degli Studi di Brescia
Acute Respiratory Tract Infections, Diarrhea
Home Based Child Care to Reduce Mortality and Malnutrition in Tribal Children of Melghat, India: CRCT
Melghat is poorly developed tribal area in India with very high child mortality \& malnutrition prevalence (grossly inadequate medical facilities). Important health problems.
- Conditions
- Acute Respiratory Tract Infections, Diarrhea, Malaria, Neonatal Sepsis
- Trial name
- HBCC (NCT02473796)
- Testing
- Home based child care
- Where
- India
- Volunteers
- 7,594 people
- Sponsor
- MAHAN Trust
Urinary Incontinence
Urge Incontinence Bladder Overactivity Study
Examine the efficacy and safety of duloxetine in subjects with symptoms of bladder overactivity due to pure detrusor instability or sensory urgency.
- Trial name
- NCT00475696
- Testing
- Duloxetine
- Where
- 3 sites in United States, Australia and 1 more
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Gastroparesis
Limited Access Protocol for the Use of Oral Cisapride
Due to the lack of other drugs to treat gastroparesis Janssen and FDA approved the compassionate use of cisapride to treat patients who had no other effective therapy.
- Trial name
- NCT02524496
- Volunteers
- 3 people
- Sponsor
- Yale University
Regional Anesthesia, Pediatric Anesthesia
Continous Lumbar Plexus Block in Children
Randomised controlled prospective trial with 2 groups (active group with Lumbar plexus block (LPB)-catheter vs control group). In a randomized controlled trial, the investigators will investigate under controlled circumstances…
- Conditions
- Regional Anesthesia, Pediatric Anesthesia, Pain, Postoperative
- Trial name
- NCT03450096
- Testing
- LPB
- Where
- Switzerland
- Volunteers
- 33 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
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