Clinical trials: Symptom
Weight, Birth, Premature Birth
Effects of Olfactory and Gustatory Stimulus on the Nutrition of Premature Babies
The objective of this clinical trial is to test the effects of olfactory and taste stimulation with milk or water in premature newborns with a gestational age between 28 and 32 weeks.
- Trial name
- NCT06305052
- Testing
- Milk, Water
- Where
- Brazil
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Professor Fernando Figueira Integral Medicine Institute
Intellectual Disability, Mild, Intellectual Disability, Mild to Moderate
PGx Medication Safety Reviews of Persons With IDD
The purpose of this study is to assess the feasibility of a comprehensive medication review and PGx initiative as part of the care process for individuals in the care of CP Unlimited.
- Conditions
- Intellectual Disability, Mild, Intellectual Disability, Mild to Moderate, Developmental Disability
- Trial name
- NCT07092852
- Testing
- Cheek swab for PGx testing, Medication safety review
- Where
- 2 sites in United States
- Volunteers
- 700 people
- Sponsor
- GalenusRx, Inc.
Pneumonia, Bronchiolitis
Diagnosing Pneumonia Under Low-resource Conditions
Pneumonia is the commonest cause of death in children worldwide, killing 1.5 million children under the age of 5 years, every year. This is more than the number of children dying from AIDS, malaria and tuberculosis combined.
- Conditions
- Pneumonia, Bronchiolitis, Asthma
- Trial name
- NCT01997047
- Where
- Canada
- Volunteers
- 502 people
- Sponsor
- University of British Columbia
Treatment-resistant Depression
Action of Ketamine in Treatment-Resistant Depression
Depression carries the largest burden of all medical disorders in middle to high income countries, as determined by the World Health Organization.
- Trial name
- NCT01945047
- Testing
- Ketamine, Midazolam
- Where
- Canada
- Volunteers
- 46 people
- Sponsor
- University of Ottawa
Gastroparesis
Medtronic Enterra II Neurostimulator
Humanitarian Device: Authorized by Federal (U.S.A.) Law for use in treatment of chronic intractable (drug refractory) nausea and vomiting secondary to gastroparesis of diabetic or idiopathic etiology.
- Trial name
- NCT06215547
- Testing
- Enterra HDE
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Methodist Health System
Myotonic Dystrophy, Congenital, Myotonic Dystrophy, Type 1 (DM1)
Music Intervention for Brain-Heart Disease in Myotonic Dystrophy Type 1 (DM1)
The goal of this interventional study is to demonstrate the feasibility and tolerability of music and movement intervention for children with congenital DM1, while providing indications of its effectiveness in improving brain and…
- Conditions
- Myotonic Dystrophy, Congenital, Myotonic Dystrophy, Type 1 (DM1), Myotonic Dystrophy Type 1, Myotonic Dystrophy Type 1 (DM1)
- Trial name
- NCT06809049
- Testing
- Music and movement education
- Where
- Canada
- Volunteers
- 13 people
- Sponsor
- Hanns Lochmuller
Cervical Radiculopathy, Cervical Root Compression
Örebro Multicenter Study on Operative Treatment of Cervical Radiculopathy
This study compares anterior cervical decompression and fusion (ACDF) to posterior foraminotomy (PF) in surgical treatment for cervical radiculopathy (CR) caused by root canal compression, in a multicenter prospective randomized…
- Trial name
- OMSAP (NCT04177849)
- Testing
- ACDF, PF
- Where
- 4 sites in Sweden
- Volunteers
- 110 people
- Sponsor
- Region Örebro County
Depression, OCD
Retrospective Analyses of the Greenbrook Database Evaluating Mental Health Treatments
The study involves multiple retrospective analyses to understand the utilization of mental health treatments provided at Greenbrook and their effectiveness
- Conditions
- Depression, OCD, Anxiety Depression
- Trial name
- NCT06997549
- Testing
- Patients treated with NeuroStar TMS, Patients treated with Esketamine
- Where
- United States
- Volunteers
- 12,000 people
- Sponsor
- Neuronetics
Chronic Musculoskeletal Pain, Pain
Diagnostic and Prognostic Biomarkers for High-impact Chronic Pain: Development and Validation
To identify diagnostic and prognostic biomarker signatures of recovery versus having persisting high-impact chronic pain and functional disability in adults with Chronic Musculoskeletal Pain.
- Conditions
- Chronic Musculoskeletal Pain, Pain, Pain, Chronic, Joint Pain
- Trial name
- NCT04994249
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Stanford University
Low Back Pain
Comparison of Spinal Kinematics Between Asymptomatic Subjects and Patients With Low Back Pain
Low back pain (LBP) is a complex and common problem with major societal repercussions. Clinical evaluations, and especially functional assessments, are necessary for proper diagnosis and decisions on the most appropriate…
- Trial name
- NCT02278549
- Where
- Switzerland
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Haute Ecole de Santé Vaud
Partial Seizures
Pregabalin Versus Levetiracetam In Partial Seizures
This study will compare pregabalin and levetiracetam in patients with partial seizures. It will also evaluate the safety and tolerability of pregabalin and levetiracetam in these patients.
- Trial name
- NCT00537238
- Testing
- pregabalin, levetiracetam
- Where
- 72 sites in Belgium, Bulgaria and 19 more
- Volunteers
- 509 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Surgical Site Infection
Wound Protector Dual-ring Alexis® in Pancreaticoduodenectomy
Surgical site infection (SSI) is a leading cause of preventable morbidity and mortality in North America and worldwide. This condition has consistently been reported to account for up to 25% of all healthcare-associated…
- Trial name
- PALEXIS (NCT03820648)
- Testing
- Alexis, Standard 3M™ Steri-Drape 2
- Where
- Italy
- Volunteers
- 212 people
- Sponsor
- Azienda Ospedaliera Universitaria Integrata Verona
Benign Prostate Hypertrophy(BPH)
Orientation Video Training Administered at Different Times to Patients Undergoing Prostate Surgery on Postoperative Pain and Anxiety (Video Training)
This study aims to evaluate the effect of operating room orientation video education delivered at different time points on postoperative pain and state anxiety in patients undergoing surgery for benign prostatic hyperplasia.
- Trial name
- NCT07778355
- Testing
- Operating Room Orientation Video Education, Routine Preoperative Information
- Where
- Turkey (Türkiye)
- Volunteers
- 126 people
- Sponsor
- Ondokuz Mayıs University
Vasculitis, Wegener's Granulomatosis
Treatment of Wegener's Granulomatosis With Cyclophosphamide
The purpose of this protocol is to continue to treat patients with Wegener's granulomatosis who have already entered the study, and to treat new patients.
- Trial name
- NCT00001155
- Testing
- cyclophosphamide
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Pelvic Organ Prolapse (POP), Pelvic Organ Prolapse Vaginal Surgery
Vaginal Mesh Surgery Versus Robotic-assisted Abdominal Mesh Surgery in the Treatment of Apical Prolapse - Prospective Randomized Non-inferiority Study
The goal of this study is to compare vaginal mesh surgery with abdominal robotic-assisted mesh surgery for the treatment of genital prolapse in women.
- Conditions
- Pelvic Organ Prolapse (POP), Pelvic Organ Prolapse Vaginal Surgery, Mesh Reinforcement, Vaginal Apex/Uterine Prolapse
- Trial name
- NCT07359755
- Testing
- Vaginal mesh surgery for apical prolapse, Robotic-assisted abdominal mesh surgery with Upsylon device (Boston Scientific - USA) for vaginal apical prolapse
- Where
- Brazil
- Volunteers
- 86 people
- Sponsor
- University of Sao Paulo General Hospital
Delirium, Postoperative
Modulating Surgery-Induced Blood-Brain Barrier Disruption in Elderly
Postoperative delirium (POD) is the most common complications (~50-60%) in elderly and major challenges to our rapidly growing aging population.
- Trial name
- NCT06090955
- Testing
- Dexmedetomidine Injection [Precedex], Lidocaine IV, normal saline
- Where
- South Korea
- Volunteers
- 108 people
- Sponsor
- Samsung Medical Center
Pain, Satisfaction, Patient
Examining the Impact of Mindfulness on Patients' Experience of Osteopathic Manipulation
This is a single site, two-arm, parallel group pilot randomized controlled trial examining the effect of coupling a brief mindfulness-based intervention with an osteopathic manipulation session for pain patients.
- Trial name
- NCT04477278
- Testing
- Mindfulness Meditation, History of Osteopathy
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of Utah
Obesity, Mild Cognitive Impairment
Improvement of Fish Oil in Obesity With Mild Cognitive Impairment
Eighty-eight patients with obesity with mild cognitive impairment（MCI） from the Multicenter Nutrition and Chronic Disease Cohort, who met the inclusion and exclusion criteria, were selected as study subjects and randomly divided…
- Trial name
- NCT06992726
- Testing
- Fish oil intervention
- Volunteers
- 88 people
- Sponsor
- Weiwei Ma
Instrument-assisted Soft Tissue Mobilization, Treatment
Investigation of The Effect of "Instrument-Assisted Soft Tissue Mobilization" in Individuals With Lumbar Disc Herniation
Instrument-assisted soft tissue mobilization is an instrument-assisted soft tissue mobilization technique. It consists of stainless steel instrument designed to adapt to various tissues/shapes/curves of the body.
- Conditions
- Instrument-assisted Soft Tissue Mobilization, Treatment, Exercise, Pain
- Trial name
- NCT06529926
- Testing
- Observational, IASTM Technique Application
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Inonu University
Low Back Pain
Myofascial Release and Joint Mobilization Therapy in Non-Specific Low Back Pain
Low back pain is a common condition affecting many individuals at some point in their lives. The prevalence of Non-specific low back pain (LBP) is between 4.2% and 19.6%, which is responsible for high treatment costs, sick leave…
- Trial name
- NCT04860726
- Testing
- Joint mobilization, Myofascial Release, Joint mobilization & Myofascial Release
- Where
- 2 sites in Pakistan
- Volunteers
- 84 people
- Sponsor
- Riphah International University
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