Clinical trials: Symptom Assessment
Irreversible Pulpitis (Toothache)
Laser Assisted Pulpotomy Versus MTA Pulpotomy in Permanent Teeth With Irreversible Pulpitis
This study compares two methods used during full pulpotomy, a treatment for teeth with deep tooth decay that has exposed the dental pulp.
- Trial name
- NCT07761962
- Testing
- Diode laser full pulpotomy, Sodium hypochlorite pulpotomy
- Where
- Jordan
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
Obesity, Aging
Obesity, Inflammation and Aging: Effects of Physical Exercise and Omega-3 Fatty Acids.
Dysfunction of adipose tissue in obesity, inflammation and aging: mechanisms and effects of physical exercise and omega-3 fatty acids.
- Conditions
- Obesity, Aging, Inflammation
- Trial name
- OBELEX (NCT03300388)
- Testing
- Omega-3 (DHA-rich dietary supplement), Resistance training
- Where
- Spain
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Clinica Universidad de Navarra, Universidad de Navarra
Depressive Symptoms
Effects of a Blended Indoor and Outdoor Physical Exercise Program on Depressive Symptoms in Hong Kong Older Adults
Depression is a mental health problem often occurring in the elderly. Performing physical exercise is a key element in decreasing depressive symptoms in older adults.
- Trial name
- NCT06190327
- Testing
- Blended indoor and outdoor multicomponent structured exercise, Indoor-only multicomponent structured exercise
- Where
- Hong Kong
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Hong Kong Baptist University
Liver Cirrhosis
A Study to Investigate the Blood Concentrations of 4 Different Oral Doses of Zibotentan in Healthy Non-Asian and Japanese Participants
This study aim to assess the Pharmacokinetics of Zibotentan in Healthy Non-Asian and Japanese Participants.
- Trial name
- NCT06715670
- Testing
- Zibotentan
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Brain Injuries
Language Assessment and Treatment Following Acquired Brain Injury
People with acquired brain injury (ABI) often experience persistent language challenges that are subtle in nature and not readily observable to others.
- Trial name
- NCT03320954
- Testing
- Anomia treatment
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- University of Nebraska Lincoln
Arthroplasty, Overweight and Obesity
Healthy Living After Knee Replacement
The purpose of this study is to examine if a weight loss program designed for adults after knee replacement improves weight loss, physical activity, pain, and function, as well as if the program is cost effective, as compared to…
- Trial name
- NCT05190666
- Testing
- PACE Weight Loss program, Chronic Disease Self-Management
- Where
- United States
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Depression, Stress
Effects of Landscapes on the Brain
There is an established consensus between researchers that the contact with natural environments has beneficial influence on mental health and well-being of people exposed to them.
- Conditions
- Depression, Stress, Anxiety Disorders
- Trial name
- NCT04210856
- Testing
- Contemplative landscape exposure
- Where
- Singapore
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Xerostomia
Potential of an Experimental Mouthwash Formulation to Reduce Dry Mouth Symptoms
This will be a single center, 7-day, examiner blind, two treatment-arm, randomized, stratified (Sjogren's Syndrome status [Y/N]), parallel group study conducted in participants experiencing dry mouth symptoms.
- Trial name
- NCT02641912
- Testing
- Biotene mouthwash, Mineral Water
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Death, HIV Infection
Community-based Evaluation of a Pilot PMTCT Project in Kafue District
In this study, the investigators will assess the population effectiveness of using routine HAART as a PMTCT strategy, through a community-based survey.
- Trial name
- NCT00753428
- Testing
- Community-based Survey
- Where
- Zambia
- Volunteers
- 4,129 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Small Intestinal Bacterial Overgrowth, Gastrointestinal Disorder, Functional
Therapeutic Effect of Olive Leaf Tea on SIBO
The goal of this study is to learn about the effect of olive leaf tea (OLT) in patients with small intestinal bacterial overgrowth aging from 18 to 60 years old.
- Trial name
- SIBO (NCT05915767)
- Testing
- Olive leaf tea
- Where
- Pakistan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Veterinary and Animal Sciences, Lahore - Pakistan
Obesity, Cardiovascular Disease
Healthy Bodies, Healthy Hearts: A Physical Activity Intervention Trial
The overall aim of Healthy Bodies, Healthy Hearts research study is to promote physical activity in women aged 45-65 years to promote reduced risk of cardiovascular disease.
- Conditions
- Obesity, Cardiovascular Disease, High Blood Pressure
- Trial name
- HBHH (NCT01099007)
- Testing
- In Person, At Home
- Where
- United States
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Nausea and Vomiting, Chemotherapy-Induced
The Pharmacokinetic Interaction Between Oral Casopitant and Oral Dolasetron, Granisetron or Rosiglitazone in Subjects
This A Three-Part Drug-Drug Interaction Study To Evaluate Effects of Casopitant On Dolasetron, Granisetron or Rosiglitazone When Co-Administered in Healthy Adults
- Trial name
- NCT00511823
- Testing
- casopitant, dolasetron, granisetron
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Low Back Pain
RCT of Motor Imagery of Extension for LBP vs. Exercise
Low back pain (LBP) is the most common musculoskeletal condition treated in physical therapy, accounting for an estimated 25-40% of outpatient physical therapy visits.
- Trial name
- NCT04394494
- Testing
- Motor Imagery. Imaging doing Extension exercises without actually doing them., Control: Physically performing extension based exercises.
- Where
- 4 sites in United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- St. Ambrose University
Low Back Pain
Assessment of All Spine Segments ın Individuals With Low Back Pain
The aim of the study is to evaluate the kinematics of all spine segments in 3 planes and compare them with asymptomatic controls using wearable technology while performing functional tasks that patients with chronic low back pain…
- Trial name
- NCT06276322
- Testing
- Low back pain group, Healthy group
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Alzheimer Disease, Mild Cognitive Impairment
Evaluation of a Computerized Complex Instrumental Activities of Daily Living Marker (NMI)
The proposed study is designed to evaluate the performance of the ALTOIDA™ System as a tool to assist physicians in diagnosing Alzheimer's Disease (AD) in real-world clinical settings.
- Conditions
- Alzheimer Disease, Mild Cognitive Impairment, Memory Disorders, Cognitive Impairment
- Trial name
- AltoidaML (NCT02843529)
- Testing
- Altoida: neuropsychological, MRI, EEG and CSF biomarkers
- Volunteers
- 548 people, healthy volunteers welcome
- Sponsor
- Altoida
Rare Diseases, Congenital Disorders
Vocal Pattern Assessment as a New Key to Identifying Rare Syndromes
Primary Study Objective The primary objective of the study is the definition of distinct vocal phenotypes and the development of an Explained Decision Support System (DSS) for the automatic detection of vocal patterns in relation…
- Trial name
- FONOTIPO (NCT05955794)
- Testing
- voice recordings
- Where
- Italy
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Pulp Necrosis, Periapical Lesion
Success Rate of Single Versus Two Visit Regenerative Treatment Protocol in Non Vital Mature Anterior Teeth
This study evaluates success rate of non vital mature anterior teeth with periapical lesion treated by regenerative endodontic protocol in single visit versus two visit technique.
- Conditions
- Pulp Necrosis, Periapical Lesion, Anterior Teeth
- Trial name
- NCT03717337
- Testing
- Single visit pulp regeneration, Two visit pulp regeneration
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Obesity, Behavior, Health
Evaluation of Brain Activity Changes After a Behavior Change Weight Loss Intervention
The aim of this study is to compare brain changes in individuals with overweight or obesity enrolled in either the Noom Healthy Weight program or a matched control.
- Conditions
- Obesity, Behavior, Health, Weight Loss
- Trial name
- NCT04522245
- Testing
- Noom Healthy Weight; mobile behavior change program for weight loss., Matched Control
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Noom Inc.
Dry Eye Symptoms
Evaluation of the Effectiveness of Auricular Acupuncture in Improving Dry Eye Symptoms in University Students
Dry eye symptoms can cause various discomforts in the eyes and/or visual disturbances. This condition not only limits daily personal activities and reduces quality of life and mental health but also has negative economic impacts…
- Trial name
- NCT06876077
- Testing
- Auricular acupuncture, Artificial Tears (AT)
- Where
- Vietnam
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Obesity
Nudging Students Towards Healthy Diet and Physical Activity to Prevent Obesity
The objective of the present study is to estimate the effect of nudging proposals on the students' Body Mass Index, based on changes made in the school environment.
- Trial name
- PAAPASNudge (NCT03128775)
- Testing
- Nudge, Primary prevention, Primary prevention + nudge
- Where
- Brazil
- Volunteers
- healthy volunteers welcome
- Sponsor
- Rio de Janeiro State University
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