Clinical trials: Symptom Management
Diabetes
Harnessing Health IT for Self-Management Support and Medication Activation in a Medicaid Health Plan
To measure the effects of a Medical health plan-directed automated telephone self-management support system (ATSM) on patient outcomes among ethnically diverse health plan enrollees with diabetes.
- Trial name
- SMARTSteps (NCT00683020)
- Testing
- ATSM Intervention
- Where
- United States
- Volunteers
- 362 people
- Sponsor
- University of California, San Francisco
Cirrhosis, Liver
Improving Pain Management and Opioid Safety for Patients With Cirrhosis
This project aims to test a behavioral intervention in patients with liver cirrhosis and chronic pain and teach self pain-management skills.
- Trial name
- NCT05128578
- Testing
- Liver Education About Pain (LEAP), Usual Care
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Pittsburgh
Iron Deficiency, Iron Deficiency Anemia
Ferric Citrate in Managing Serum Phosphorus and Iron Deficiency in Anemic Chronic Kidney Disease (CKD) Subjects Not on Dialysis
The purpose of this study is to determine if KRX-0502 (ferric citrate) is a safe and effective treatment for the management of serum phosphorus levels and iron deficiency in anemic chronic kidney disease (CKD) stage 3-5 subjects…
- Trial name
- NCT01736397
- Testing
- Ferric Citrate
- Where
- 20 sites in United States
- Volunteers
- 149 people
- Sponsor
- Keryx Biopharmaceuticals
Pain Management
Analgesic Efficacy of (MSIR)/Acetaminophen vs. Oxycodone/Acetaminophen (Percocet)
Oxycodone and Hydrocodone are the most commonly used oral opioid analgesics in the emergency department and in outpatient settings.
- Trial name
- NCT03088826
- Testing
- Morphine Sulfate, Oxycodone, Acetaminophen
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Antonios Likourezos
Pain, Postoperative
Perioperative Administration of Pregabalin for Pain After Mastectomy
The investigators hypothesize that pregabalin will decrease post-operative pain scores and analgesic use following total mastectomy compared to placebo.
- Trial name
- NCT00938548
- Testing
- Pregabalin
- Where
- South Korea
- Volunteers
- 70 people
- Sponsor
- Severance Hospital
Sepsis, Infection
Paediatric Rapid Sepsis Trigger (PRST) Tool
Sepsis is the leading cause of death and disability in children, every hour of delay in treatment is associated with greater organ damage and ultimately death.
- Trial name
- PRST (NCT04304235)
- Testing
- Pediatric Rapid Sepsis Trigger (PRST) tool, Emergency Triage and Treatment (ETAT) guidelines
- Where
- 3 sites in Kenya, Uganda
- Volunteers
- 18,693 people
- Sponsor
- University of British Columbia
Acute Pain
Benzodiazepines for the Reduction of Distress and Pain During and After Emergency Department Care
In this proposal, the investigators will determine if a single dose of oral lorazepam reduces distress, pain severity, and need for opiate analgesics both in the ED and in the acute recovery period after discharge.
- Trial name
- NCT03756038
- Testing
- Lorazepam
- Where
- 2 sites in United States
- Volunteers
- 1 people
- Sponsor
- Maria Pacella
Apnea of Prematurity, Intraventricular Hemorrhage
MRI and Neurodevelopment in Preterm Infants Following Administration of High-Dose Caffeine
Over the last 30 years the survival rates for babies born prematurely have improved greatly with research. As these babies grow up, we have found that many of the premature babies have learning and movement problems.
- Conditions
- Apnea of Prematurity, Intraventricular Hemorrhage, Brain Injury
- Trial name
- NCT00809055
- Testing
- Caffeine citrate
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- Washington University School of Medicine
Weight Loss, Obesity
Weight Management in Rural Communities
The goal of this study is to evaluate the effect of three weight management interventions (group phone conference calls, individual phone calls, and enhanced usual care) on weight across 18 months in overweight and obese adults…
- Conditions
- Weight Loss, Obesity, Body Weight
- Trial name
- M-DEx (NCT02932748)
- Testing
- Portion Controlled Meals (PCM), Group Phone (GP), Conventional Diet
- Where
- United States
- Volunteers
- 187 people
- Sponsor
- University of Kansas
Diabetes
HealthyMe Online Weight Management Education/HealthyMe at Home
The main objective for this project is to identify effective methods of treating obesity in at-risk populations. The investigators will be comparing weight loss from usual care, in person, and video conference weight loss…
- Trial name
- HOME (NCT02057952)
- Testing
- Education and exercise
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Indiana University
Hemorrhage
This Study Looks at the Effects of Idarucizumab in Patients Who Take Dabigatran and Need Emergency Surgery or Are Bleeding
The primary objective is to demonstrate reversal of the anticoagulant effect of dabigatran in patients treated with dabigatran etexilate who have uncontrolled or life-threatening bleeding requiring urgent intervention, and in…
- Trial name
- NCT03343704
- Testing
- Idarucizumab
- Where
- 13 sites in China
- Volunteers
- 19 people
- Sponsor
- Boehringer Ingelheim
Grief
Experiencing Loss and Planning Ahead Study
The course of dementia over many years, gradual losses and uncertain life expectancy can lead to grief amongst family and friend carers.
- Trial name
- ELPAS (NCT03332979)
- Where
- United Kingdom
- Volunteers
- 150 people
- Sponsor
- University College, London
Musculoskeletal Injury
Oral Analgesic Utilization for CHildhood Musculoskeletal Injuries
Pain management for children presenting to the emergency department (ED) with an injured limb is often under-treated, even though it is known that broken arms and legs cause moderate to severe pain.
- Trial name
- NCT02064894
- Testing
- oral morphine and oral ibuprofen, Oral morphine, Oral ibuprofen
- Where
- 3 sites in Canada
- Volunteers
- 501 people
- Sponsor
- St. Justine's Hospital
PTSD, Overweight
MOVE!+UP: Testing a Tailored Weight Management Program for Veterans With PTSD
Posttraumatic Stress Disorder (PTSD) is common among Veterans and results in poor psychological functioning, quality of life, and physical health.
- Conditions
- PTSD, Overweight, Obesity
- Trial name
- NCT04563741
- Testing
- MOVE!+UP, MOVE!
- Where
- United States
- Volunteers
- 174 people
- Sponsor
- VA Office of Research and Development
Multiple Sclerosis
Fatigue Management Programs for People With MS
This is a multi-site randomized clinical trial comparing 3 modes of delivering the Managing Fatigue course for reducing fatigue in individuals with multiple sclerosis (MS).
- Trial name
- NCT03550170
- Testing
- Teleconference, Internet, 1-to-1, in-person or videoconference
- Where
- 3 sites in United States
- Volunteers
- 590 people
- Sponsor
- Case Western Reserve University
Abortion in First Trimester
Auriculotherapy - Pain Management of Aspiration Abortion
Primary Objective: To assess whether usual care plus auricular acupressure with beads reduces subject-reported maximum pain during first trimester vacuum aspiration compared to usual care plus placebo.
- Trial name
- NCT03896022
- Testing
- Acupressure with Beads, Acupuncture with Needles
- Where
- United States
- Volunteers
- 177 people, healthy volunteers welcome
- Sponsor
- Columbia University
Pain, Chronic
Cooperative Pain Education and Self-management: Expanding Treatment for Real-world Access (COPES ExTRA)
To conduct a superiority trial of COPES versus standard Veterans Health Administration (VHA) Cognitive Behavioral Therapy Chronic Pain (CBT-CP)
- Trial name
- COPES ExTRA (NCT03469505)
- Testing
- COPES, CBT-CP
- Where
- 9 sites in United States
- Volunteers
- 764 people
- Sponsor
- Yale University
Immune Thrombocytopenia
Eltrombopag vs Standard Front Line Management for Newly Diagnosed Immune Thrombocytopenia (ITP) in Children
This is an investigator initiated, multicenter, open label, randomized phase 3 study for subjects with newly diagnosed ITP from ages 1 to less than 18 years old.
- Trial name
- NCT03939637
- Testing
- Eltrombopag, Steroids, IVIG
- Where
- 27 sites in United States
- Volunteers
- 122 people
- Sponsor
- Baylor College of Medicine
Pain, Acute, Anesthesia, Local
Perineural Local Anesthetic Administration With a Continuous Infusion Versus Automatic Intermittent Boluses
This will be a randomized comparison of continuous local anesthetic infusion with patient controlled boluses (PCA) to automated boluses with PCA for continuous popliteal sciatic nerve blocks.
- Conditions
- Pain, Acute, Anesthesia, Local, Trauma Injury
- Trial name
- NCT04458467
- Testing
- Continuous Infusion, Automated Intermittent Boluses
- Where
- United States
- Volunteers
- 71 people
- Sponsor
- University of California, San Diego
Acute Respiratory Failure
DirEct Versus VIdeo LaryngosCopE Trial
Clinicians perform rapid sequence induction, laryngoscopy, and tracheal intubation for more than 5 million critically ill adults as a part of clinical care each year in the United States.
- Trial name
- DEVICE (NCT05239195)
- Testing
- Video Laryngoscope, Direct Laryngoscope
- Where
- 12 sites in United States
- Volunteers
- 1,420 people
- Sponsor
- Vanderbilt University Medical Center
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