Clinical trials: Symptom Monitoring
Residual Neuromuscular Blockade
Electromyographic and Acceleromyographic Monitoring in Restricted Arm Movement Surgical Setting
Researchers are comparing the ease of use and repeatability of the force vs electrical activity produced by a muscle after it has undergone nerve stimulation during a surgical procedure in which the patients' arm movement is…
- Trial name
- NCT04352140
- Testing
- Tetragraph, ToFscan
- Where
- 3 sites in United States, France and 1 more
- Volunteers
- 60 people
- Sponsor
- Mayo Clinic
Cardiac Output, Low
Comparison Between NICOM-Cheetah and Flotrac-Vigileo for Cardiac Output Monitoring.
Cardiac output (CO) monitoring is an important tool in critically ill patients with haemodynamic instability. Traditionally, this has been accomplished using the pulmonary artery catheter (PAC).
- Trial name
- NCT03394768
- Testing
- No additional intervention
- Where
- Singapore
- Volunteers
- 26 people
- Sponsor
- Changi General Hospital
Renal Insufficiency, Chronic, Hypertension
Supporting Self-Management of Healthy Behaviors in Diabetes, Kidney Disease, and Hypertension
The planned intervention, entitled, Supporting Self-Management of Health Behaviors to Optimize Health (SMART-HABITS for Health), aims to provide support for patients with chronic kidney disease (CKD), hypertension and diabetes by…
- Conditions
- Renal Insufficiency, Chronic, Hypertension, Diabetes
- Trial name
- NCT05565716
- Testing
- Support Person, Social Norms
- Where
- United States
- Volunteers
- 73 people
- Sponsor
- University of Pennsylvania
Atrial Fibrillation, Behavior
Patient Centered Mobile Health Technology Enabled Atrial Fibrillation Management
The overall objective of this proposal is to evaluate the feasibility of a comprehensive digital atrial fibrillation (AFib) management tool that will empower patients to a) take an active role in learning about AFib management…
- Trial name
- mTECHAFib (NCT05400837)
- Testing
- Corrie Virtual Atrial Fibrillation Management Program
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- Johns Hopkins University
Myocardial Infarction, Myocardial Infarction, Acute
BIO monitorinG in Patients With Preserved Left ventricUlar Function AfteR Diagnosed Myocardial Infarction
The BIO|GUARD-MI study investigates whether continuous arrhythmia monitoring and the consequent treatment after detected arrhythmias in patients after myocardial infarction with preserved cardiac function, but other risk factors…
- Conditions
- Myocardial Infarction, Myocardial Infarction, Acute, Myocardial Infarction Old
- Trial name
- BIO-GUARD-MI (NCT02341534)
- Testing
- BioMonitor
- Where
- 59 sites in United States, Australia and 12 more
- Volunteers
- 802 people
- Sponsor
- Biotronik SE & Co. KG
Septic Shock
PK Analysis of Piperacillin in Septic Shock Patients
Antibiotic dosing in septic shock patients poses a challenge for clinicians due to the pharmacokinetic changes seen in this population.
- Trial name
- NCT02306928
- Testing
- Blood draw
- Where
- Denmark
- Volunteers
- 15 people
- Sponsor
- University of Aarhus
Syncope
Ambulatory Post-Syncope Arrhythmia Protection Feasibility Study
The purpose of this study is to conduct an observational investigation of a novel care path used to manage emergency department (ED) presenting syncope patients on an outpatient basis.
- Trial name
- ASAP (NCT02188147)
- Testing
- Short Term Wearable Defibrillator
- Where
- 6 sites in United States
- Volunteers
- 39 people
- Sponsor
- Zoll Medical Corporation
Atrial Fibrillation, Atrial Flutter
Combined Use of BIOTRONIK Home Monitoring and Predefined Anticoagulation to Reduce Stroke Risk
The IMPACT Study will investigate the potential clinical benefit of the combined use of BIOTRONIK Home Monitoring (HM) technology and a predefined anticoagulation plan compared to conventional device evaluation and…
- Conditions
- Atrial Fibrillation, Atrial Flutter, Stroke, Embolism, Systemic Arterial
- Trial name
- IMPACT (NCT00559988)
- Testing
- Home Monitoring Guided OAC, Physician-Directed OAC
- Where
- 80 sites in United States, Australia and 4 more
- Volunteers
- 2,718 people
- Sponsor
- Biotronik, Inc.
Chronic Spontaneous Urticaria
A Multicenter, Open-label Phase 3 Study: Ambulatory Blood Pressure Monitoring in Adult Patients With Chronic Spontaneous Urticaria Inadequately Controlled by H1-antihistamines Treated With Remibrutinib up to 12 Weeks.
The purpose of this study was to assess the effect of remibrutinib 25 mg twice a day (b.i.d.) open-label on Systolic Blood Pressure (SBP) measured as a change in 24-hour weighted average SBP from baseline to Week 4 assessed by…
- Trial name
- NCT05795153
- Testing
- LOU064
- Where
- 44 sites in United States, Argentina and 8 more
- Volunteers
- 144 people
- Sponsor
- Novartis Pharmaceuticals
Pulmonary Disease, Chronic Obstructive
A Study to Investigate the Association of Real-world Sensor-derived Biometric Data With Clinical Parameters and Patient-reported Outcomes for Monitoring Disease Activity in Patients With COPD
The purpose of this multicenter, prospective cohort study is to investigate the correlation of real-world sensor-derived biometric data obtained via a wearable device with clinical parameters and patient-reported outcomes (PROs)…
- Trial name
- NCT05655832
- Testing
- Vivalink wearable device
- Where
- 11 sites in Germany
- Volunteers
- 77 people
- Sponsor
- Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany
Brain Injuries, Traumatic
Treatment and Recovery Monitoring of Post TBI Symptoms
This proposal aims to investigate the effect of a promising treatment for persistent post Traumatic Brain Injury (TBI) symptoms, and to monitor TBI patient's recovery by an objective technique along with standard clinical…
- Trial name
- NCT02426749
- Testing
- Active repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- Canada
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Hepatitis B, Chronic
Chronic HBV Management for Asian American
About 75% of liver cancers are attributed to chronic hepatitis B (CHB). An estimated 2.2 million individuals in the U.S. have CHB. Although Asian Americans make up 6% of total U.S.
- Trial name
- NCT04082338
- Testing
- VPN, TM
- Where
- 2 sites in United States
- Volunteers
- 382 people
- Sponsor
- Temple University
Breast Cancer
An Integrated Consent Model Study to Compare Two Standard of Care Schedules for Monitoring Cardiac Function in Patients Receiving Trastuzumab for Early Stage Breast Cancer
Several large adjuvant trastuzumab trials have demonstrated improved overall survival in participants with early stage breast cancer, with a 33% decrease in risk of death.
- Trial name
- OTT 15-05 (NCT02696707)
- Testing
- LVEF 3 month, LVEF 4 month
- Where
- 4 sites in Canada
- Volunteers
- 200 people
- Sponsor
- Ottawa Hospital Research Institute
Cardiac Arrest
Augmented Multimodal Neurologic Monitoring in High Risk Survivors of Cardiac Arrest
Cardiac arrest is the most common cause of death in the United States and as many as 590,000 Americans suffering a cardiac arrest each year.
- Trial name
- NCT02069353
- Testing
- QFlow 500™ Perfusion Probe (Hemedex, Cambridge, MA), Spencer Probe Depth Electrode (Ad-Tech Medical, Racine, WI)
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Jonathan Elmer
HIV Infections, Viremia
Enhanced Virologic Monitoring for Pregnant and Postpartum Women With HIV
The goal of this study is to learn about supporting pregnant and postpartum women living with HIV with treatment adherence. The investigators will conduct a pilot study of an intervention that includes peer counseling about viral…
- Conditions
- HIV Infections, Viremia, Pregnancy Related
- Trial name
- NCT05845619
- Testing
- Enhanced virologic monitoring
- Where
- 4 sites in Kenya
- Volunteers
- 550 people
- Sponsor
- University of California, San Francisco
Delayed Emergence From Anesthesia
Recovery Profile Comparison Between Remifentanil-propofol or Desflurane Anesthesia Monitored With Bispectral Index.
Bispectral monitoring anesthesia with remifentanil-desflurane has a better post-operative recovery than remifentanil-propofol.
- Trial name
- NCT02631525
- Testing
- Desflurane, Propofol
- Volunteers
- 40 people
- Sponsor
- Federal University of Minas Gerais
Hypoglycemia Unawareness, Type 1 Diabetes
Glucose Counterregulation in Long Standing Type 1 Diabetes
Enrollment for this study is complete. This study is designed to determine if use of a real-time continuous glucose monitor (RT-CGM) can reverse defective Glucose counter regulation and hypoglycemia unawareness in long standing…
- Conditions
- Hypoglycemia Unawareness, Type 1 Diabetes, Healthy
- Trial name
- NCT01474889
- Testing
- RT-CGM
- Where
- 3 sites in United States
- Volunteers
- 37 people
- Sponsor
- University of Pennsylvania
Chronic Kidney Diseases, Type 2 Diabetes
Continuous Glucose Monitoring to Assess Glycemia in Chronic Kidney Disease - Changing Glucose Management
The goal of this study is to test whether a dipeptidyl peptidase-4 inhibitor, compared with a sulfonylurea, improves time in normal blood glucose range and reduces blood glucose variability.
- Trial name
- CANDY-CANE (NCT02608177)
- Testing
- Linagliptin, Glipizide
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- University of Washington
Heart Arrhythmia
Feasibility Study of the µCor Heart Failure and Arrhythmia Management System (PATCH)
Prospective, non-interventional, feasibility study. 8 months, from start of screening to finishing the study. Multi-center study, with a maximum of 8 centers in Europe.
- Trial name
- PATCH (NCT04512703)
- Testing
- µCor
- Where
- Germany
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Zoll Medical Corporation
Acute Coronary Syndrome, Coronary Stent Occlusion
Perioperative Management of Patients With Coronary Stents Undergoing Noncardiac Surgery
The purpose of this study is to evaluate and monitor perioperative management of patients with coronary stents undergoing noncardiac surgery.
- Conditions
- Acute Coronary Syndrome, Coronary Stent Occlusion, Surgery
- Trial name
- RegistStents (NCT01171612)
- Where
- 13 sites in Spain
- Volunteers
- 483 people
- Sponsor
- Corporacion Parc Tauli