Clinical trials: Symptomatic Irreversible Pulpitis
Mandibular Nerve, Mandibular Nerve Blocks
Comparative Assessment of Mental/Incisive and Inferior Alveolar Nerve Block Anesthesia in Root Canal Treatment of Mandibular Premolars
The goal of this clinical trial is to systematically compare the pain scores and anesthesia efficacy of IANB and MNB in the treatment of symptomatic mandibular first and second premolars.
- Conditions
- Mandibular Nerve, Mandibular Nerve Blocks, Premolars, Mental Nerve Block
- Trial name
- NCT06679660
- Testing
- inferior alveolar nerve block with 4% articaine, Mental/Incisive Nerve Block (%4 Articaine)
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Pulpitis
Celebrex Premedication in Teeth With Symptomatic Irreversible Pulpitis
Assessing the efficacy of Celebrex premedication on pain during and after endodontic treatment in teeth with symptomatic irreversible pulpits
- Trial name
- NCT03339544
- Testing
- Celebrex premedication
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Cairo University
Drug Effect, Pulpitis - Irreversible
Different Volumes of Articaine for Inferior Alveolar Nerve Block in Irreversible Pulpitis
This is a randomized controlled trial comparing the anaesthetic efficacy of 1.8 and 3.6 mL of Articaine for inferior alveolar nerve block when treating mandibular molars with Irreversible Pulpitis
- Trial name
- IANB (NCT05840913)
- Testing
- Articaine HCl 4 % / EPINEPHrine 1:100,000 in 1.8 mL Dental Cartridge
- Where
- 2 sites in Pakistan
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Armed Forces Institute of Dentistry, Pakistan
Post Operative Pain After Root Canal Therapy
Postoperative Pain Comparison of Two Root Canal Sealers in Irreversible Pulpitis
This study, approved by the Institutional Ethics Review Committee, AFID (Annex "A"), will involve 62 eligible patients from the Operative Dentistry Department, Armed Forces Institute of Dentistry.
- Trial name
- NCT06975761
- Testing
- Resin Based sealer, ZnO eugenol based sealers
- Where
- Pakistan
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Armed Forces Institute of Dentistry, Pakistan
Postoperative Pain
Comparative Evaluation of the Efficacy of Intraoral Cryotherapy Versus Intracanal Cryotherapy on Postoperative Pain
The aim of this study is to clinically compare the efficacy of intraoral cryotherapy versus intracanal cryotherapy after single visit root canal therapy in lower molars with irreversible pulpitis and symptomatic apical…
- Trial name
- NCT05041738
- Testing
- Intraoral Cryotherapy, Intracanal Cryotherapy
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Cairo University
Endodontically Treated Teeth
Outcome of NSRCT Versus VPT in Management of Teeth with Symptomatic Irreversible Pulpitis Associated with Apical Periodontitis
Pulpitis is the pulpal inflammation in response to irritants which are either microbial, chemical, or physical (mechanical and thermal) in origin.
- Trial name
- NCT06226870
- Testing
- root canal tretment, biodentin VPT, PRF
- Where
- Egypt
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Minia University
Irriversible Pulpitis, Irrigation
Comparison of Post-operative Pain After Different Root Canal Irrigant Activation Methods
root canal irrigation protocol
- Conditions
- Irriversible Pulpitis, Irrigation, Activation, Patient
- Trial name
- NCT07196215
- Testing
- passive ultrasonic activation, sonic activation
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- RANA AHMAD
Pain, Procedural
Two Approaches in Enhancing the Efficacy of Inferior Alveolar Nerve Block During Treatment of Mandibular First Permanent Molars With Symptomatic Irreversible Pulpitis
The study is designed as a randomized parallel controlled trial with three groups. Participants aged above 18 years with the first permanent molars with symptomatic signs of irreversible pulpitis will be randomly assigned into 3…
- Trial name
- NCT05427903
- Testing
- Cryotherapy, Buccal local anesthetic infiltration using articaine 4% 1:100000 epinephrine
- Where
- Egypt
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Minia University
Irreversible Pulpitis
The Effect of Intra-pulpal Anesthesia With Cryotherapy on Intra-operative Pain
The goal of this clinical trial is to compare the effect of cooling of local anesthesia on intraoperative pain during root canal treatment in mandibular molars diagnosed as symptomatic irreversible pulpitis.
- Trial name
- NCT06194721
- Testing
- Cold intrapulpal anesthesia, Room temperature intrapulpal anesthesia
- Where
- United Arab Emirates
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Gulf Medical University
Teeth With Acute Irreverseble Pulpitis
Evaluation of the Effect of Intra-ligamentary Injection of Diclofenac Potassium Versus Articaine on Anaesthetic Efficacy in Mandibular Molars With Symptomatic Irreversible Pulpitis.
This study aims to assess the effect the intraligamentary injection of Diclofenac Potassium versus Articaine 4% on the anaesthetic efficacy \& intensity of intraoperative \& postoperative pain during single visit root canal…
- Trial name
- NCT06500871
- Testing
- Diclofenac Potassium
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Failed Mechanical Induction
Efficacy of Two Injection Techniques on Success Rate of Inferior Alveolar Nerve Anesthesia
Forty healthy patients with including criteria who failed to infra alveolar nerve block injection (without lip numbness) have been randomly divided into two groups on a random basis and have received Gow-Gates or another inferior…
- Trial name
- NCT02543619
- Testing
- Injection technique
- Where
- Iran
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Azad University of Medical Sciences
Symptomatic Irreversible Pulpitis
The Effect of Buccal Infiltration Administration of Clonidine on the Success Rate of Inferior Alveolar Nerve Block
Articaine/epinephrine and lidocaine/epinephrine are the most common routine local anesthetic agents currently used in dentistry.
- Trial name
- NCT04186299
- Testing
- Clonidine, Articaine Hydrochloride + Epinephrine
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Pulpitis - Irreversible
Full Pulpotomy Versus Root Canal Treatment for Teeth With Symptomatic Irreversible Pulpitis
Background The European Society of Endodontology (ESE) and the American Association of Endodontists (AAE) position statements on the management of deep caries and exposed pulp recommended adoption and promotion of strategies…
- Trial name
- NCT06002698
- Testing
- Root canal treatment (Control), Full pulpotomy (Experimental)
- Where
- Malaysia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Pulpitis - Irreversible
Comparison Between Intraligamentary Piroxicam and Articaine
Comparing the efficacy of intra-ligamentary Piroxicam and intra-ligamentary Articaine on pain during and after endodontic treatment of mandibular molars with symptomatic irreversible pulpitis.
- Trial name
- NCT03612323
- Testing
- Intra-ligamentary Piroxicam, Intra-ligamentary Articaine
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Irreversible Pulpitis
Pulpotomy in Vital Primary Molars Diagnosed With Symptomatic Irreversible Pulpitis
This is a clinical trial to assess the treatment outcomes of pulpotomy in vital primary molars diagnosed with symptomatic irreversible pulpitis.
- Trial name
- NCT06149845
- Testing
- Full Pulpotomy
- Where
- 2 sites in Qatar
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Qatar University
Success of Inferior Alveolar Nerve Block
Effect of Magnesium Sulphate Added to Mepivacaine Hydrochloride on Inferior Alveolar Nerve Block Success in Patients With Symptomatic Irreversible Pulpitis in Mandibular Molars: A Randomized Clinical Trial.
the study is conducted to assess the effect of adding magnesium sulphate to mepivacaine HCl compared to mepivacaine HCl alone on the success of inferior alveolar nerve block in patients with symptomatic irreversible pulpitis in…
- Trial name
- NCT04561921
- Testing
- Magnesium sulfate, Mepivacaine-Levonordefrin Hydrochloride
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Cairo University
Symptomatic Irreversible Pulpitis (SIP)
Effect of Intracanal Cryotherapy Versus Laser Application on Postoperative-pain and Bacterial Load Reduction in Single Visit Root Canal Treatment in Patients With Symptomatic Irreversible Pulpitis in Mandibular First Molar Teeth (Randomized Control Trial)
This randomized controlled clinical trial investigates the Effect of Intracanal Cryotherapy Versus Laser Application on Post-Operative Pain and Bacterial Load Reduction in Single-Visit Root Canal Treatment in Patients with…
- Trial name
- NCT07627867
- Testing
- final irrigation by NaOcl at room temperature, final irrigation by Cryotreated NaOcl, final irrigation by preheated NaOcl
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Symptomatic Irreversible Pulpitis
Comparison Between M-Pro and ProTaper Next
Comparing the postoperative pain resulting after mechanical instrumentation using M-pro files versus that resulting after using ProTaper Next rotary files in lower molar with symptomatic Irreversible pulpitis molars.
- Trial name
- NCT03692039
- Testing
- M-pro files in rotating motion, ProTaper Next files in rotating motion
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Symptomatic Irreversible Pulpitis
Postoperative Pain Intensity After Pulpotomy
Introduction: This study aimed to compare postoperative pain rates following sodium hypochlorite (NaOCl) and KTP laser-assisted pulpotomy treatments in permanent teeth with deep caries, and symptomatic irreversible pulpitis.
- Trial name
- NCT05424796
- Testing
- Physiological saline, Hemostasis and cavity disinfection with NaOCl, Hemostasis and cavity disinfection with KTP laser
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Cumhuriyet University
Postoperative Pain
Effect of Passive Ultrasonic Irrigation Activation Cycle on Postoperative Pain
One of the most important goals of root canal treatment is to eliminate bacteria from infected canals. However, conventional irrigation methods combined with mechanical preparation applied during root canal treatment may not be…
- Trial name
- NCT06711029
- Testing
- Conventional needle irrigation, Passive Ultrasonic Irrigation with 3*20 sn, Passive Ultrasonic Irrigation with 6*10 sn
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Esin Özlek