Clinical trials: Symptomatic Irreversible Pulpitis
Symptomatic Irreversible Pulpitis
Efficacy of Pulpal Anesthesia and Patient Preference Using the Needle-less and Conventional Injection Techniques
Pain despite being a physiological experience, is considerably affected by the emotional states, such as anxiety and fear. It was demonstrated that individuals with a high level of anxiety experience difficult anesthesia and more…
- Trial name
- NCT05724862
- Testing
- Needle-less jet anaesthesia, Conventional Injection Anesthesia
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Cairo University
Post Operative Endodontic Pain
Reduction of Post-operative Endodontic Pain
To determine the effect of intraligamentary injection of Lornoxicam on the intensity of post-operative endodontic pain in the tooth with symptomatic irreversible pulpitis.
- Trial name
- NCT01480752
- Testing
- Lornoxicam, normal saline, no injection
- Where
- Iran
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Islamic Azad University, Sanandaj
Pulpitis - Irreversible
Outcome Following Endodontic Treatment Using Traditional Access Versus Conservative Access
This study will compare the outcome of endodontic treatment using conservative or traditional access design in permanent molars with clinical signs indicative of irreversible pulpitis
- Trial name
- NCT05402098
- Testing
- Endodontic treatment using traditional access, Endodontic treatment using conservative access
- Where
- India
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Symptomatic Irreversible Pulpitis
Effect Of XP Endo Finisher Versus Ultrasonic Activated Irrigation On Post-operative Pain In Endodontic Treatment of Symptomatic Irreversible Pulpitis
Recruited patients with symptomatic irreversible pulpitis are assigned to interventional (XP Endo Finisher file) and control group(ultrasonic activated irrigation) to undergo single visit endodontic treatment and record…
- Trial name
- RCT (NCT03096587)
- Testing
- XP Endo Finisher, ultrasonic activated irrigation
- Where
- Egypt
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Cairo University
Irreversible Pulpitis
Treatment Outcomes of Pulpotomy Versus Pulpectomy in Vital Primary Molars Diagnosed With Irreversible Pulpitis
This randomised controlled trial aims to compare treatment outcomes between pulpotomy and pulpectomy when used to treat vital primary molars diagnosed with symptomatic irreversible pulpitis.
- Trial name
- NCT06904781
- Testing
- Pulpotomy, Pulpectomy
- Where
- 2 sites in Jordan, Qatar
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Qatar University
Effect of Photobiomodulation Using Diode Laser
The Effect of Photobiomodulation Using Low-Level Diode Laser Therapy on Postoperative Pain in Symptomatic Lower Molar Teeth With Irreversible Pulpitis and Apical Periodontitis; a Randomized Controlled Clinical Trial
this study aims to assess the effect of photobiomodulation using low-level diode laser therapy on postoperative pain after single-visit root canal treatment of mandibular molars with symptomatic irreversible pulpitis and apical…
- Trial name
- NCT06396130
- Testing
- Photobiomodulation by low level diode laser, Mock Laser Application
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Root Canal Infection
Success Rate of 4 Injection Protocols for Mandibular First Molars With Symptomatic Irreversible Pulpitis
Achieving profound anesthesia during endodontic treatment of mandibular molars with symptomatic irreversible pulpitis is still a demanding clinical challenge.
- Trial name
- NCT04929522
- Testing
- local anesthesia
- Where
- Egypt
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Pain, Symptomatic Irreversible Pulpitis
Ethyl Chloride Versus 5% Lidocaine for Topical Anesthesia of Oral Mucosa
Local anesthesia in the oral cavity is a pain full experience for the patient. All means should be made to reduce the pain and anxiety of the patient for needle stick procedures.
- Trial name
- NCT05306470
- Testing
- Ethyl chloride, 5% lidocaine gel
- Where
- Pakistan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Altamash Institute of Dental Medicine
Symptomatic Irreversible Pulpitis
Comparison of Anesthetic Efficacy of Mental Nerve Block Versus Inferior Alveolar Nerve Block in Mandibular Anterior Teeth and Premolars in Symptomatic Irreversible Pulpitis
Symptomatic irreversible pulpitis is a painful condition that requires anesthesia to perform effective dental procedures. The mental nerve block and inferior alveolar nerve block are two commonly used techniques for achieving…
- Trial name
- NCT06333730
- Testing
- inferior alveolar nerve block, mental nerve block
- Where
- Pakistan
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Prime Foundation
Post-endodontic Pain
Comparison Of The Effect Of Final Rinse Of Tramadol and Dexamethasone on Post-Endodontic Pain in Teeth With SIP
Briefly, 105 teeth with symptomatic irreversible pulpitis will be included in the study and randomly allocated to three groups (A, B and C).
- Trial name
- NCT07036237
- Testing
- Tramadol group, Dexamethasone Group
- Where
- Pakistan
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Pulpitis
Assessment of Postoperative Pain After Using Reciproc Versus One Shape NiTi Systems
The aim of this study is to assess the postoperative pain and the intake of analgesic medication after using Reciproc single-file reciprocating system or One Shape single-file continuous rotary system in patients with symptomatic…
- Trial name
- NCT02940704
- Testing
- Reciproc, One Shape
- Where
- Egypt
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Cairo University
Postoperative Pain
Effect of Pretreatment Dexamethazone on Pain and Success of Nerve Block
A Comparative Evaluation of the effect of pretreatment dexamethasone versus placebo on post-endodontic pain and success of inferior alveolar nerve block in Mandibular molars with symptomatic Irreversible Pulpitis: A Blinded…
- Trial name
- NCT03199482
- Testing
- Dexamethasone Oral Tablet
- Where
- Egypt
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pulpitis - Irreversible
Evaluation of the Effect of Adding Dexamethasone to 2% Lidocaine
This randomized, double-blind clinical trial aimed at the evaluation of the effect of adding dexamethasone to 2% lidocaine, given as inferior alveolar nerve block in the endodontic management of symptomatic irreversible pulpitis.
- Trial name
- NCT05361291
- Testing
- Lidocaine Hydrochloride
- Where
- India
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Jamia Millia Islamia
Symptomatic Irreversible Pulpitis
Assessment of Pain and Treatment Success After VPT Versus RCT in Mature Permanent Mandibular Molars With SIP: A RCT
Assessment of postoperative pain and treatment success after vital pulp therapy versus root canal treatment in mandibular molar with signs and symptoms of irreversible pulpitis.
- Trial name
- NCT05681494
- Testing
- Root canal treatment, Vital pulp therapy
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Cairo University
Symptomatic Irreversible Pulpitis
Assessment of Local Anaesthesia Effectiveness in Symptomatic Irreversible Pulpitis
This study aims to evaluate the comparative efficacy of two different local anaesthetic agents for supplemental buccal infiltration after a failed inferior alveolar nerve block in achieving profound pulpal anaesthesia for…
- Trial name
- LA AGENTS (NCT06862570)
- Testing
- 2% lignocaine with epinephrine 1.8 ml(36mg/ml lignocaine HCL, epinephrine bitartrate 0.0324mg/ml), 4% Articaine with epinephrine 1.7 ml (40mg/ml Articaine HCL, epinephrine bitartrate 0.018 mg/ml)
- Where
- Pakistan
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- 28 Military Dental Centre Lahore
Post-operative Pain, Irreversible Pulpitis
Relationship of Eye Colour With Anesthetic Success and Post-Operative Pain
Current evidence indicates that some phenotypic characteristics, such as eye or hair color, might be associated with the experience of pain.
- Trial name
- NCT06206304
- Testing
- Root canal therapy
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Mustafa Kemal University
Concerned Growth Factor Versus Miniral Trioide Aggregate in Management of Mature Permanent Molar With Irreversible Pulpitis
Concerned Growth Factor VS Miniral Trioide Aggregate in Treatment of Mature Permanent Teeth of Children With Symptomatic Irreversible Pulpitis.
Concerned Growth factor versus Miniral Trioide aggregate in management of Mature permanent Molar of children with irreversible pulpitis
- Trial name
- NCT07138287
- Testing
- Concerned Growth factor in management of Mature permanent Molar with irreversible pulpitis
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Minia University
Pulp Disease, Dental, Pulpitis
Predicting Vital Pulp Treatment Outcomes in Symptomatic Pulpits Using Metabolic Biomarker
This prospective controlled clinical trial investigates whether metabolic biomarkers measured in pulpal blood at the time of carious pulp exposure can predict the 12-month outcomes of vital pulp treatment in symptomatic permanent…
- Conditions
- Pulp Disease, Dental, Pulpitis, Reversible Pulpitis, Irreversible Pulpitis (Toothache)
- Trial name
- NCT07452614
- Testing
- vital pulp treatment
- Where
- Iraq
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Abeer Ghalib Abdul-khaliq
Symptomatic Irreversible Pulpitis
Effect of Ultrasonic Activation of Bioceramic Sealer on Postoperative Pain in Lower Premolars
The aim of this study is to clinically compare post-operative pain levels after ultrasonic activation of Ceraseal bioceramic sealer versus non-activated bioceramic sealer for patients with symptomatic irreversible pulpitis…
- Trial name
- NCT05289791
- Testing
- ultrasonic activation of bioceramic sealer
- Where
- Egypt
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Cairo University
Symptomatic Irreversible Pulpitis
Combination of Buffered Anesthetic to Treat Mandibular Molars
The purpose of this study is to determine whether a combination of anesthetics (numbing medicine) will adequately anesthetize teeth over a different combination.
- Trial name
- NCT06047366
- Testing
- Sodium bicarbonate, Lidocaine w/ epi, Articaine w/ epi
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Indiana University