Clinical trials: Symptomatic Irreversible Pulpitis and Post Operative Pain
Symptomatic Irreversible Pulpitis (SIP)
Effect of Intracanal Cryotherapy Versus Laser Application on Postoperative-pain and Bacterial Load Reduction in Single Visit Root Canal Treatment in Patients With Symptomatic Irreversible Pulpitis in Mandibular First Molar Teeth (Randomized Control Trial)
This randomized controlled clinical trial investigates the Effect of Intracanal Cryotherapy Versus Laser Application on Post-Operative Pain and Bacterial Load Reduction in Single-Visit Root Canal Treatment in Patients with…
- Trial name
- NCT07627867
- Testing
- final irrigation by NaOcl at room temperature, final irrigation by Cryotreated NaOcl, final irrigation by preheated NaOcl
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Symptomatic Irreversible Pulpitis
Comparison Between M-Pro and ProTaper Next
Comparing the postoperative pain resulting after mechanical instrumentation using M-pro files versus that resulting after using ProTaper Next rotary files in lower molar with symptomatic Irreversible pulpitis molars.
- Trial name
- NCT03692039
- Testing
- M-pro files in rotating motion, ProTaper Next files in rotating motion
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Symptomatic Irreversible Pulpitis
Postoperative Pain Intensity After Pulpotomy
Introduction: This study aimed to compare postoperative pain rates following sodium hypochlorite (NaOCl) and KTP laser-assisted pulpotomy treatments in permanent teeth with deep caries, and symptomatic irreversible pulpitis.
- Trial name
- NCT05424796
- Testing
- Physiological saline, Hemostasis and cavity disinfection with NaOCl, Hemostasis and cavity disinfection with KTP laser
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Cumhuriyet University
Postoperative Pain
Effect of Passive Ultrasonic Irrigation Activation Cycle on Postoperative Pain
One of the most important goals of root canal treatment is to eliminate bacteria from infected canals. However, conventional irrigation methods combined with mechanical preparation applied during root canal treatment may not be…
- Trial name
- NCT06711029
- Testing
- Conventional needle irrigation, Passive Ultrasonic Irrigation with 3*20 sn, Passive Ultrasonic Irrigation with 6*10 sn
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Esin Özlek
Pain, Postoperative, Irreversible Pulpitis
Comparison of Nitrofurantoin and Calcium Hydroxide as Intracanal Medicaments in Alleviating Post-operative Pain
Intracanal medicaments have been frequently used in patients with endodontic and periradicular infection for the elimination of microorganisms.
- Trial name
- NCT04900571
- Testing
- Nitrofurantoin 100 MG
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Altamash Institute of Dental Medicine
Postoperative Pain, Symptomatic Irreversible Pulpitis
Effect of Apical Patency and Local Corticosteroid on Pain and Neuropeptides Release in Patients With Symptomatic Irreversible Pulpitis: A Randomized Clinical Trial
The goal of this randomized clinical trial is to learn the effect of using local corticosteroids and maintaining apical patency in reducing post-preparation pain in patients with acute irreversible pulpitis in molar teeth.
- Trial name
- NCT06457828
- Testing
- Non-corticosteroid injection, Corticosteroid injection
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Suez Canal University
Symptomatic Irreversible Pulpitis and Post Operative Pain
Laser-Assisted vs Conventional Total Pulpotomy in Symptomatic Irreversible Pulpitis
his randomized controlled clinical trial will compare laser-assisted total pulpotomy with conventional total pulpotomy in permanent molar teeth diagnosed with symptomatic irreversible pulpitis.
- Trial name
- LASERPULP (NCT07850258)
- Testing
- Conventional Total Pulpotomy, Laser-Assisted Total Pulpotomy
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- meliksahgunduz
Symptomatic Irreversible Pulpitis, Apical Periodontitis
Postoperative Pain and Healing in Teeth Treated With GentleWave or EndoActivator
Patients with painful molars will be randomly assigned to 2 different groups: GentleWave and EndoActivator. The root canals will be completed using identical protocols except in the mode of delivery and activation of irrigation…
- Trial name
- NCT04552132
- Testing
- Multisonic vs Sonic activation of irrigants
- Where
- United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- St. Louis University
Symptomatic Irreversible Pulpitis
The Effect of Three Different Medications on Anesthetic Success and Postoperative Pain
Pain is a very important factor in Endodontic treatment, Both intra- and Post-operatively. In case of symptomatic Irreversible pulpitis, a build up of inflammatory mediators makes it very difficult for the operator to reach the…
- Trial name
- NCT06298383
- Testing
- Trypsin, Bromelain and Rutoside, Diclofenac Potassium 50mg Tab, Prednisolone Oral Tablet
- Where
- 2 sites in Egypt
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Cairo University
Symptomatic Irreversible Pulpitis, Post Operative Pain
Effect of Preoperative Tramadol and Naproxen Sodium on Post Operative Pain
The goal of this clinical trial is to compare in Tramadol, Naproxen sodium and Placebo in participants presenting with irreversible pulpitis in their mandibular molar teeth.
- Trial name
- NCT05982392
- Testing
- Tramadol, Naproxen Sodium
- Where
- Pakistan
- Volunteers
- 139 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Post-operative Pain
Evaluation of Post-operative Pain and Expression of IL-8 Using Ketolac or Cryoirrigation as a Final Flush in Single Visit Endodontic Treatment in Teeth With Symptomatic Irreversible Pulpitis and Apical Periodontitis.Randomized Clinical Trial.
To compare the effect of cryotherapy versus ketorolac tromethamine irrigating solutions used as a final flush in single visit endodontic treatment in mandibular molars, with symptomatic irreversible pulpitis and apical…
- Trial name
- NCT04733326
- Testing
- Ketorolac Tromethamine, Cryotherapy, Saline
- Where
- Egypt
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Cairo University
Postoperative Pain
Occlusal Reduction and Postoperative Pain
The purpose of this randomized clinical study was to evaluate the impact of occlusal reduction on the incidences of post-instrumentation and post-obturation pain. Forty four patients were included in this study.
- Trial name
- NCT03117062
- Testing
- occlusal reduction
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Cairo University
Postoperative Pain
Comparative Evaluation of the Effect of Prophylactic Intraligamentary Injection of Dexamethasone and Piroxicam on Postoperative Pain in Teeth With Symptomatic Irreversible Pulpitis
the study is conducted to assess and compare the efficacy of local intraligamentary injection of glucocorticoids(dexamethasone) and NSAID(piroxicam) on reduction of postoperative pain in patients with symptomatic irreversible…
- Trial name
- NCT03745105
- Testing
- Dexamethasone sodium phosphate, Piroxicam Injectable Solution, Mepivacaine HCL
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Cairo University
Symptomatic Irreversible Pulpitis
The Effect of XP-Endo Finisher Activation of Bioceramic Sealer on Postoperative Pain in Mandibular First Molar With Symptomatic Irreversible Pulpitis
The aim of endodontic obturation is to make a complete sealing along the length of the root canal system to ensuring the peri radicular tissue healing and sustained health.
- Trial name
- NCT06640231
- Testing
- sealer activation after cleaning and shaping with XP-Endo Finisher, negative control where canals are obturated directly without sealer activation
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Post-operative Pain, Pulpitis - Irreversible
Outcomes of Pulpotomy and Root Canal Treatment in Teeth With Symptomatic Irreversible Pulpitis
The aim of this study is to evaluate the clinical effectiveness of total pulpotomy (TP), radicular pulpotomy (RP), and root canal treatment (RCT) in mandibular premolar and/or molar teeth diagnosed with symptomatic irreversible…
- Conditions
- Post-operative Pain, Pulpitis - Irreversible, Success Rate
- Trial name
- NCT07375576
- Testing
- Total Pulpotomy, Radicular pulpotomy, Root canal treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Mustafa Kemal University
Evaluate Occlusal Reduction on Post-operative Pain, Teeth With Symptomatic Irreversible Pulpitis
Effect of Occlusal Reduction on Post-operative Pain
effect of occlusal reduction on post-operative pain is evaluated after single visit root canal treatment in upper and lower molar teeth in patients with sypmtomatic irreversible pulpitis and apical periondontis
- Conditions
- Evaluate Occlusal Reduction on Post-operative Pain, Teeth With Symptomatic Irreversible Pulpitis, Apical Periodontitis
- Trial name
- NCT03189771
- Testing
- occlusal surface reduction
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Cairo University
Symptomatic Irreversible Pulpitis (SIP)
Measure Postoperative Pain and Bacterial Reduction After Different Final Irrigation Protocols.
The primary objective of root canal treatment is to clean, disinfect, and hermetically seal the root canal system to prevent bacterial penetration; however, postoperative pain is frequently encountered, particularly in patients…
- Trial name
- PIRRI (NCT07191990)
- Testing
- Final irrigation by cryotreated NaOcl., Final irrigation by preheated NaOcl, Final irrigation with ultrasonic activation of NaOcl
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Symptomatic Irreversible Pulpitis
Effect Of XP Endo Finisher Versus Ultrasonic Activated Irrigation On Post-operative Pain In Endodontic Treatment of Symptomatic Irreversible Pulpitis
Recruited patients with symptomatic irreversible pulpitis are assigned to interventional (XP Endo Finisher file) and control group(ultrasonic activated irrigation) to undergo single visit endodontic treatment and record…
- Trial name
- RCT (NCT03096587)
- Testing
- XP Endo Finisher, ultrasonic activated irrigation
- Where
- Egypt
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Cairo University
Effect of Photobiomodulation Using Diode Laser
The Effect of Photobiomodulation Using Low-Level Diode Laser Therapy on Postoperative Pain in Symptomatic Lower Molar Teeth With Irreversible Pulpitis and Apical Periodontitis; a Randomized Controlled Clinical Trial
this study aims to assess the effect of photobiomodulation using low-level diode laser therapy on postoperative pain after single-visit root canal treatment of mandibular molars with symptomatic irreversible pulpitis and apical…
- Trial name
- NCT06396130
- Testing
- Photobiomodulation by low level diode laser, Mock Laser Application
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pulpitis
Assessment of Postoperative Pain After Using Reciproc Versus One Shape NiTi Systems
The aim of this study is to assess the postoperative pain and the intake of analgesic medication after using Reciproc single-file reciprocating system or One Shape single-file continuous rotary system in patients with symptomatic…
- Trial name
- NCT02940704
- Testing
- Reciproc, One Shape
- Where
- Egypt
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Cairo University