Clinical trials: Symptoms, Behavioral
Mental Fatigue, Recovery
Effects of Different Nap Durations on Volleyball Performance and EEG Activity Following Mental Fatigue
Mental fatigue is known to impair cognitive and physical performance in athletes, but the effectiveness of different nap durations in counteracting these effects remains unclear.
- Conditions
- Mental Fatigue, Recovery, Volleyball, Sport Performance
- Trial name
- MFNAP (NCT07700576)
- Testing
- Mental Fatigue Induction, Control Condition, Daytime Nap 20 Minutes
- Where
- Turkey (Türkiye)
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Inonu University
Depression
A Pilot Study of eHealth Tools in a Tertiary-care Setting
This feasibility study investigates the use of eHealth tools within routine medical treatment for patients with depression in an outpatient psychiatric setting.
- Trial name
- NCT03762460
- Testing
- Online eHealth tool, Informational website
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University of British Columbia
Depressive Disorder, Major
Self Neuro-modulation Therapy for Major Depressive Disorder (MDD) With Anhedonia
The purpose of this research is to learn more about a new treatment for individuals with Major Depressive Disorder (MDD) with heightened symptoms of anhedonia (i.e. loss of pleasure or interest in activities).
- Trial name
- NCT06982820
- Testing
- Prism Training
- Where
- 3 sites in United States, Israel
- Volunteers
- 170 people
- Sponsor
- GrayMatters Health Ltd.
Chronic Fatigue Syndrome/ Myalgic Encephalitis (CFS/ME), Post COVID Syndrome
Effectiveness and Safety of a Tele-Rehabilitation Program on Fatigue and Related Variables in Chronic Fatigue Syndrome and Post COVID Syndrome
This is a randomized, single-blind clinical trial that aims to evaluate the effectiveness of a tele-rehabilitation program based on mindful and conscious movement-based exercise (including adapted yoga, breathing exercises, and…
- Trial name
- NCT06978582
- Testing
- Mindful and conscious movement-based exercise, Conventional exercise
- Where
- Spain
- Volunteers
- 147 people
- Sponsor
- University of Seville
Body Weight, Health Behavior
Body Weight, Body Composition and Energy Balance Related Behavior During the Transition to Parenthood
Understanding critical periods during which people are at risk to gain weight or display unhealthy changes in energy balance related behaviour, i.e.
- Conditions
- Body Weight, Health Behavior, Pregnancy, First Pregnancy
- Trial name
- TRANSPARENTS (NCT03454958)
- Testing
- Measurements of body composition
- Where
- 4 sites in Belgium
- Volunteers
- 304 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Obesity
Extended Evening Fasting: Metabolic Health and Energy Balance
This study will compare metabolic and feeding behaviour responses to 4 days of extended evening fasting vs. a control trial
- Trial name
- NCT04924517
- Testing
- Extended Evening Fasting, Control
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Nottingham Trent University
Chronic Disease, Mental Health
Alaska Alliance for Community Engagement Phase II: Partnership for Action Toward Health
The AK ACE-PATH Phase II study aims to pilot and implement a novel intervention, Tools for Arctic Health Promotion (TAHP), to address Alaska Native (AN) community priorities related to local health and community-level resilience.
- Conditions
- Chronic Disease, Mental Health, Caridovascular Disease, Stress
- Trial name
- AK ACE-PATH (NCT07801989)
- Testing
- Tools for Arctic Health Promotion
- Where
- United States
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- University of Alaska Fairbanks
Depression, Depressive Disorder
Study Evaluating Desvenlafaxine Succinate Sustained Release (DVS SR) Versus Placebo in Peri- and Postmenopausal Women
Desvenlafaxine succinate (DVS) is a potent and selective serotonin and norepinephrine reuptake inhibitor (SNRI). The sustained-release (SR) formulation, DVS SR, is being studied in the development program for the treatment of…
- Conditions
- Depression, Depressive Disorder, Depressive Disorder, Major
- Trial name
- NCT00369343
- Testing
- Desvenlafaxine administered as a succinate salt in a sustained-release form (DVS SR)
- Where
- 37 sites in United States
- Volunteers
- 381 people
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Anhedonia, Depression
Sleep and Healthy Aging Research on Depression for Younger Women
Compelling evidence indicates inflammation plays a role in depression, but potential mechanisms linking inflammation to depression, such as dysregulated reward processing, are poorly understood.
- Trial name
- NCT03848715
- Testing
- Endotoxin
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Psychiatric/Mood Disorder | Patient, Estrogen Receptor Levels
Validation of [18F]FES for Imaging of Brain Estrogen Receptors
Validation of [18F]-FES for imaging of estrogen receptors in the brain The primary objective of the study is to determine if [18F]-FES Positron Emission Tomography (PET) can be used to quantify the estrogen receptor expression in…
- Conditions
- Psychiatric/Mood Disorder | Patient, Estrogen Receptor Levels, Premenopausal, Postmenopausal
- Trial name
- NCT01842217
- Testing
- FES-PET
- Where
- Netherlands
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- University Medical Center Groningen
Facial Palsy
Relationship Between Facial Palsy and Psychological Distress
The goal of this observational cross-sectional study is to investigate whether the severity of facial dysfunction is associated with psychological distress in patients with unilateral facial palsy.
- Trial name
- FNP-Psy (NCT07511140)
- Where
- Egypt
- Volunteers
- 85 people
- Sponsor
- Cairo University
Cognition, Affect (Mental Function)
ETASCAN Project: ETAS Project 2
This study aims to investigate the chronic effects of ETAS® on cognitive, affective and neural outcomes in healthy adults aged 60-80 years with mild to moderate subjective cognitive complaints.
- Conditions
- Cognition, Affect (Mental Function), Sleep, MRI
- Trial name
- ETASCAN (NCT07550140)
- Testing
- ETAS®
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Reading
Abdominal Surgery, Hypertension
The Effect of Laughter Yoga on Nurses' Perceived Stress Burnout and Life Satisfaction During the Pandemic Period
This study aimed to determine the effects of laughter yoga on the perceived stress, burnout and life satisfaction of nurses working actively during the pandemic period.
- Conditions
- Abdominal Surgery, Hypertension, Done Laughter Yoga Before, Epilepsy
- Trial name
- NCT05317091
- Testing
- Laughter yoga practiced
- Where
- Turkey (Türkiye)
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Depression
Escitalopram for the Prevention of PEGASYS-associated Depression in Hepatitis C Virus-infected Patients
Primary end points incidence of depression defined as a Montgomery Asberg Depression Scale Score (MADRS) of 13 or higher during antiviral therapy (up to 48 weeks, depending on genotype) effect of an antidepressive pre-treatment…
- Trial name
- CIPPAD (NCT00136318)
- Testing
- Escitalopram, Peginterferon alfa-2a, Ribavirin
- Where
- Germany
- Volunteers
- 208 people
- Sponsor
- Charite University, Berlin, Germany
Anxiety, Depression
Anxiety With Cancer in the Elderly (ACE): A Cognitive-behavioral Intervention
The purpose of this study is to examine the feasibility and acceptability of and patient adherence to a telephone-administered cognitive-behavioral therapy intervention for anxiety in older adults (65 years and older) with cancer…
- Conditions
- Anxiety, Depression, Quality of Life
- Trial name
- NCT02747160
- Testing
- Managing Anxiety from Cancer (MAC)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Fibromyalgia, Depression - Major Depressive Disorder
Analgesic Efficacy of Multisite rTMS in Fibromyalgia Patients
Repetitive Transcranial Magnetic Stimulation (rTMS) of the motor cortex is a recognized analgesic technique for the treatment of fibromyalgia pain, which represents a largely unmet medical need.
- Conditions
- Fibromyalgia, Depression - Major Depressive Disorder, Chronic Pain
- Trial name
- MultiStimFM (NCT07642882)
- Testing
- rTMS
- Where
- France
- Volunteers
- 36 people
- Sponsor
- Hospital Ambroise Paré Paris
Long-Term Care, Caregiver Burden
Holistic Self-Empowerment Care Intervention for Optimized Independent Living and Quality of Life: A Study Protocol
This protocol describes a pilot study evaluating the effectiveness of the Self-Empowerment Care Model in promoting independence and quality of life among frail older adults in Hong Kong.
- Trial name
- NCT06736782
- Testing
- Self-Empowerment Care Intervention Group, Control Group
- Where
- Hong Kong
- Volunteers
- 207 people
- Sponsor
- The University of Hong Kong
Depression, Anxiety
Behavioral Telehealth in Low-resource Primary Care Settings for Anxiety and Depression in Youth
The goal of this clinical trial is to test a brief, behavioral telehealth treatment program (STEP-UP) for depression and anxiety in youths (age 8-16 years old).
- Trial name
- STEP-UP (NCT06273982)
- Testing
- STEP-UP (transdiagnostic behavioral therapy for pediatric anxiety and depression), ARC (assisted referral to community care)
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- San Diego State University
Temporomandibular Disorder
Effectiveness of a Home Based Exercise Program on Temporomandibular Dysfunction Syndrome
patients with chronic refractory temporomandibular dysfunction were prescribed home exercise and were followed for 6 months. Pain , mouth opening and Fonseca's were done at day 1 and after 6 months of the study.
- Trial name
- NCT04374682
- Testing
- exercises
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Assiut University
Diet, Healthy, Diet Habit
Healthy Eating Education for Latinos
This intervention aims to evaluate the efficacy of a pilot educational intervention with deep-structure cultural tailoring for Latino ethnic groups on diet quality compared to general, surface-level healthy-eating messages.
- Conditions
- Diet, Healthy, Diet Habit, Obesity, Blood Pressure
- Trial name
- NCT04724382
- Testing
- Culturally tailored healthy eating advice, Standard healthy eating advice
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
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