Clinical trials: Symptoms, Behavioral
Major Depressive Disorder
Ketamine in the Treatment of Depression
Depressed patients will be offered experimental treatment with a new, potentially fast-acting antidepressant called ketamine while being scanned by magnetic resonance imaging (MRI) to measure the chemical effect of the drug.
- Trial name
- NCT01558063
- Testing
- Ketamine, Saline, Magnetic Resonance Imaging (MRI)
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Columbia University
Quality of Life, Sexual Activity
Quality of Life and Sexual Function of the Novasure Endometrial Ablation in Menorrhagia
The aim of this study is to investigate the influence on the quality of life and sexual function before, 6 month and one year after Novasure Endometrial Ablation in the treatment of Menorrhagia.
- Trial name
- NCT01910584
- Testing
- Novasure endometrial ablation
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Shu-Qin Chen
Colon Cancer, IBS
Patient Satisfaction With Propofol for Out Patient Colonoscopy
The primary purpose of this study is to determine if patient satisfaction with propofol is better than with non-propofol anesthesia for outpatient colonoscopies.
- Conditions
- Colon Cancer, IBS, Polyps
- Trial name
- NCT02937506
- Testing
- Propofol, Fentanyl Plus Midazolam
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Mount Carmel Health System
Depression
The Therapeutic Efficacy of Neurofeedback in Depression
The investigators examined the therapeutic efficacy of neurofeedback in depression subjects. The investigators hypothesize that 5 weeks neurofeedback training will be able to alleviate depressive symptoms.
- Trial name
- neurofeedback (NCT00729547)
- Testing
- Neurofeedback
- Where
- South Korea
- Volunteers
- 24 people
- Sponsor
- Korea University
Depression
Kinetics of Fluvoxamine and Digoxin in Subjects With Different MDR1 Genotypes
The investigators will compare plasma kinetics of two marker drugs in individuals with different genetic variations in the MDR1-gene. The hypothesis is that one group will have higher exposure than the other.
- Trial name
- NCT01704638
- Testing
- fluvoxamine, Digoxin
- Where
- Sweden
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Lethal Means Counseling Skill
Pathways 2 Safety: AI-Simulated Clients for Experiential Learning in Behavioral Health Education
The goal of this study was to compare the effectiveness of practicing lethal means counseling skills with an artificial intelligence (AI)-powered client compared to practice with a live actor.
- Trial name
- NCT07873658
- Testing
- Lethal means counseling training and skills practice
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- University of Washington
Aggressive Behavior, Post-Traumatic Stress Disorder
Treatment of Aggressive Behavior and Post-Traumatic Stress Disorder
Street children and children of vulnerable families in conflict or former conflict regions are often exposed to multiple traumatic events and situations in which they are forced to engage in violent behavior.
- Trial name
- NCT01519193
- Testing
- Narrative Exposure Therapy for violent offenders (NETvo)
- Where
- Burundi
- Volunteers
- 42 people
- Sponsor
- University of Konstanz
Systemic Lupus Erythematosus (SLE)
Whole Health Empowerment for Endotypes of Lupus: Improving Quality of Life in SLE
For people living with people living with systemic lupus erythematosus (SLE) the symptoms with the largest impact on their quality of life - fatigue, pain, and brain fog - are not always addressed in rheumatology clinic visits.
- Trial name
- WHEEL (NCT06720584)
- Testing
- Health coach-led, online support program for people living with lupus
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Duke University
Depression
Using a Mentoring Afterschool Program to Improve Adolescent Mental Health and Physical Activity: A Pilot Study
Coming out of the COVID-19 pandemic many youth are experiencing declines in physical activity and worsening mental health (e.g., depression symptoms).
- Trial name
- NCT06686784
- Testing
- After School Plus
- Where
- United States
- Volunteers
- 209 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Anxiety Disorder, Breast Cancer
S1008: Exercise, Diet, & Counseling in Improving Weight Loss in Overweight Female Breast or Colorectal Cancer Survivors
RATIONALE: Physical activity, diet, and counseling may help breast and colorectal cancer survivors to lose weight and improve their quality of life.
- Conditions
- Anxiety Disorder, Breast Cancer, Cognitive/Functional Effects, Colorectal Cancer
- Trial name
- NCT01453452
- Testing
- behavioral dietary intervention, exercise intervention, counseling intervention
- Where
- 58 sites in United States
- Volunteers
- 50 people
- Sponsor
- SWOG Cancer Research Network
Suicidal Ideation, Self Harm
Augmented Momentary Personal Ecological Risk Evaluation
The goal of this intervention study is to co-design and test an Ecological Momentary Assessment (EMA) prototype tool with young adults aged 16-30 experiencing suicidality to see if it is an acceptable and usable clinical tool for…
- Trial name
- AMPERE (NCT06704958)
- Testing
- AMPERE EMA app
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- University of Washington
Type 2 Diabetes, Overweight
The Effect of Semaglutide on Disordered Eating Behaviour in Type 2 Diabetic Patients
The aim of this study is to evaluate the effect of glucagon-like peptide-1 (GLP-1) receptor agonist semaglutide on disordered eating behaviour in patients with overweight and type 2 diabetes.
- Conditions
- Type 2 Diabetes, Overweight, Disordered Eating Behaviors
- Trial name
- NCT06243536
- Testing
- Semaglutide, standard of care
- Where
- Croatia
- Volunteers
- 60 people
- Sponsor
- University Hospital Sestre Milosrdnice
Diffuse Large B-Cell Lymphoma
KPT-330 Plus RICE for Relapsed/Refractory Aggressive B-Cell Lymphoma
This study evaluates the addition of selinexor (KPT-330) to RICE chemotherapy in the treatment of relapsed and refractory aggressive B-Cell Lymphoma, with the goal of improved response rates (as compared to RICE chemotherapy…
- Trial name
- KPT-330+RICE (NCT02471911)
- Testing
- KPT-330, Rituximab, Etoposide
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Weill Medical College of Cornell University
Agitation
Nalbuphine Versus Dexmedetomidine for Prevention of Emergence Agitation in Pediatrics
the investigators hypothesized that Nalbuphine may be alternative pharmacological agent for prevention of emergence agitation in pediatrics who will be scheduled for elective lower abdominal surgical procedures (inguinal hernia…
- Trial name
- NCT05273671
- Testing
- Nalbuphine, Dexmedetomidine, normal Saline
- Where
- Egypt
- Volunteers
- 126 people
- Sponsor
- Alexandria University
Major Depressive Disorder
Dose-finding Study With Lu AA24530 in Major Depressive Disorder
The primary purpose of this study is to assess the efficacy in treating patients with Major Depressive Disorder of one or more doses of Lu AA24530 relative to placebo
- Trial name
- NCT00599911
- Testing
- Lu AA24530, Duloxetine
- Where
- 72 sites in Australia, Austria and 15 more
- Volunteers
- 652 people
- Sponsor
- H. Lundbeck A/S
Deafness, Bilateral
Study of the Role of Top-down Processes in Neuronal Reorganization and Recovery From Sensory Loss: an Exploratory Behavioral and Electroencephalographic Study in Cochlear-supported Deaf Patients
This study posits that central top-down processes (attention, inhibition), marked by alpha oscillations in EEG, play a key role.
- Trial name
- REASCENT (NCT07500909)
- Testing
- neurophysiological assessment, Cognitive, behavioral and quality of life assessment
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University Hospital, Toulouse
Traumatic Brain Injury
ACTIVE: Activity Therapy to Increase Veteran Engagement
Depression is common after traumatic brain injury (TBI) and may have wide-ranging consequences. Post-TBI depression may impede reintegration into the family and community and lead to lower quality of life and heightened suicide…
- Trial name
- ACTIVE (NCT04976621)
- Testing
- Behavioral Activation, Treatment as Usual
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- VA Office of Research and Development
Developmental Delay, Disruptive Behavior
Advancing Child Competencies by Extending Supported Services (ACCESS) for Families Program
The Advancing Child Competencies by Extending Supported Services (ACCESS) for Families Program is a study funded by the National Institutes of Health to explore behavior and developmental problems among young children aging out…
- Trial name
- ACCESS (NCT03260816)
- Testing
- Internet-delivered Parent-Child Interaction Therapy (I-PCIT), Referrals as Usual (RAU)
- Where
- 3 sites in United States
- Volunteers
- 150 people
- Sponsor
- Florida International University
Asthma in Children, Artificial Intelligence
Artificially Intelligent Robot Control
The purpose of the study is to compare the impact of standard asthma education with the standard + Artificially Intelligent Robot (AIR) Control intervention.
- Conditions
- Asthma in Children, Artificial Intelligence, Caregiver Burden
- Trial name
- AIR (NCT07738016)
- Testing
- Artificially Intelligent Robot (AIR) Control Intervention, Standard Asthma Education
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Miami
Abnormal Uterine Bleeding
Decisionmaking for Abnormal Uterine Bleeding (AUB)
The purpose of this study is to determine if using a computer survey about preferences for treatment of abnormal uterine bleeding (AUB) is useful and if it will improve patient satisfaction with clinical care and decision making.
- Trial name
- NCT01721304
- Testing
- Adaptive Conjoint Analysis
- Where
- 2 sites in United States
- Volunteers
- 380 people
- Sponsor
- Indiana University
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