Clinical trials: Symptoms, Behavioral
Psychological Distress
Well-Being Therapy by Personalized Mobile Technology Program for Psychological Distress and Promote Healthy Behaviors
The WELL-ME study is a three-arm randomized controlled clinical trial (RCT). The aim of this RCT is to compare the effectiveness of the Well Being Web Based Therapy (WBT-Web) with the gold standard CBT (Cognitive Behavior…
- Trial name
- WELL-ME (NCT01543815)
- Testing
- Well-Being Therapy based on Web Mobile Technology, Cognitive Behavior Therapy, Standardized Care Management
- Volunteers
- 400 people
- Sponsor
- University of Bergamo
Water-Related Diseases
SAFEWATER Health & Behaviour Impact Field Trials; Mexico
At least 1.8 billion people globally use a source of drinking water that is faecally contaminated and thus likely to lead to diarrheal illness: nearly 1,000 children die each day due to water and sanitation-related diarrhoeal…
- Trial name
- NCT04736615
- Testing
- SAFEWATER systems for drinking water disinfection, Behavior change interventions
- Where
- 3 sites in Colombia, Mexico
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Ulster
Pain
Vibration and Shotblocker Use in Pregnant Women While Giving Tetanus + Diphtheria Vaccine
Tetanus-diphtheria vaccine administered to pregnant women may cause pain during and after administration. Due to the pain that may occur, the compliance of pregnant women towards the vaccine may be impaired.
- Trial name
- NCT05701904
- Testing
- Local mechanical vibration, Shotblocker group
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Hasan Kalyoncu University
Neuropsychiatric Disorder, Neurological Disorder
Studying Childhood-onset Behavioral, Psychiatric, and Developmental Disorders
Background: Many psychiatric, behavioral, and developmental disorders are genetic. This means that they tend to run in families. Some begin in childhood, while others do not appear until adulthood.
- Conditions
- Neuropsychiatric Disorder, Neurological Disorder, Neurodevelopmental Disorder, Sleep
- Trial name
- NCT01778504
- Where
- United States
- Volunteers
- 237 people
- Sponsor
- National Institute of Mental Health (NIMH)
Depression, Insomnia
Treatment of Insomnia and Depression in Elders (TIDE)
Insomnia and depression are two of the most prevalent mental health disorders and often co-occur. Health disparities in rural America and among African-Americans are well documented.
- Trial name
- TIDE (NCT01648049)
- Testing
- Integrated Cognitive Behavioral Therapy (CBT), Treatment as usual
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- University of Alabama, Tuscaloosa
Self Harm, Suicidal Idealtion
Self Harm in Females of South Asian Family Origin
Aim of the study is to adapt and develop a culturally appropriate psychological intervention and to pilot test it's feasibility, and acceptability for the adult South Asian females presenting to general hospital emergency…
- Conditions
- Self Harm, Suicidal Idealtion, Hopelessness
- Trial name
- NCT00884078
- Testing
- Culturally adapted manualized problem solving training
- Where
- 3 sites in United Kingdom
- Volunteers
- 20 people
- Sponsor
- Lancashire Care NHS Foundation Trust
Congenital Heart Disease, Heart Failure
Gender Difference in NET Activation in Patients With Congenital Heart Disease and Heart Failure
Neutrophil hyperactivation has detrimental effects on cardiac tissue after injuries, leading to fibrosis lesions and cardiac dysfunction.
- Conditions
- Congenital Heart Disease, Heart Failure, Gender
- Trial name
- FIBRONETx (NCT05263843)
- Testing
- Biological markers of myocardial fibrosis
- Where
- 2 sites in France
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Sports Injury
Effect of EMS and Strengthening Exercises on Pain, Fatigue and Physical Performance in Motocross Athletes
Motocross, a popular sport, involves riding motorized vehicles on rugged tracks with obstacles. It's physically demanding, with high speeds and a risk of accidents.
- Trial name
- NCT06300385
- Testing
- Electromyostimulation, Strengthening exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Istanbul Bilgi University
Suicide, Attempted, Suicide and Self-harm
Real-time Intervention for Suicide Risk Reduction: Primary Open Pilot
The goal of this study is to provide an initial pilot test of an Ecological Momentary Intervention (EMI) designed the reduce the distress associated with negative emotion among individuals at risk for suicide that pairs content…
- Trial name
- NCT03950765
- Testing
- Ecological momentary intervention
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Rutgers, The State University of New Jersey
Depression
Magnesium Sulfate Versus 5% Dextrose With Treatment Resistant Depression
The proposed study is a 1-week, randomized, double-blind, placebo-controlled, trial to evaluate the efficacy of an IV infusion of magnesium sulfate on symptoms of treatment resistant mild and moderate depression in 20 males and…
- Trial name
- NCT01597167
- Testing
- Magnesium sulfate
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- University of Miami
Midwifery Support, Skin to Skin Contact
The Effect of Skin-to-skin Contact at Birth
To determine the effects of skin-to-skin contact at birth on birth outcomes (placental delivery time, postpartum pain level, time of first breastfeeding, and breastfeeding motivation) and on postpartum parenting behavior.
- Conditions
- Midwifery Support, Skin to Skin Contact, Parenthood Status
- Trial name
- NCT07656207
- Testing
- Immediate skin-to-skin contact after birth (intervention group)
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Gaziantep Islam Science and Technology University
Menopause, Insomnia
The Treatment of Insomnia in Symptomatic Peri- and Postmenopausal Women
To examine the change in sleep patterns and mood symptoms in response to eszopiclone (Lunesta) using a double-blind placebo-controlled cross-over study design in perimenopausal and postmenopausal women who experience insomnia…
- Trial name
- NCT00374192
- Testing
- Eszopiclone
- Where
- United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Cancer, Cancer Cachexia
Flexi Band Resistance Training Versus EMS Exercise in Patients With the Diagnosis of Malignant Diseases
The purpose of this study is to investigate the effects of a 12-week flexi band resistance training program compared to different whole-body electromyostimulation (WB-EMS) exercise programs on muscle strength, body composition…
- Conditions
- Cancer, Cancer Cachexia, Inflammation, Muscular Atrophy
- Trial name
- FREEDOM (NCT04067167)
- Testing
- WB-EMS, Free WB-EMS, Flexi band resistance training
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
Suicide, Suicide, Attempted
A Brief Intervention to Reduce Suicide Risk in Military Service Members and Veterans - Study 2 (SAFEMIL)
The investigators propose to test the efficacy of a brief, readily accessible, and personalized treatment called the Safety Planning for Military (SAFE MIL; Stanley and Brown, 2012).
- Trial name
- SAFEMIL (NCT01360736)
- Testing
- Safety Planning - Military (SAFE MIL)
- Where
- 2 sites in United States
- Volunteers
- 102 people
- Sponsor
- Henry M. Jackson Foundation for the Advancement of Military Medicine
Major Depressive Disorder
A Comparison of Cognitive and Dynamic Therapy for Depression in Community Settings
The goal of this study is to compare supportive-expressive therapy, a type of psychodynamic psychotherapy, with cognitive therapy for the treatment of depression in community mental health consumers.
- Trial name
- NCT01207271
- Testing
- Cognitive Therapy, Supportive-Expressive Psychodynamic Therapy
- Where
- United States
- Volunteers
- 237 people
- Sponsor
- University of Pennsylvania
Suicidal Ideation and Behavior
Stepped-Care for Suicidal Youth and Children
The goal of this RCT study is to test the efficacy of a stratified stepped-care (SSC) model in reducing suicidal thoughts and behaviors (STB) in children and adolescents. The main questions it aims to answer are: 1.
- Trial name
- SURE-CARE (NCT07321171)
- Testing
- IPC-A-SCI (Interpersonal Counseling for Suicide Crisis Intervention), IPT-A-SCI (Interpersonal Psychotherapy for Adolescents with Suicidal Crisis Intervention)
- Where
- Israel
- Volunteers
- 350 people
- Sponsor
- Shira Barzilay
Healthy, COPD
Effects of BFR Interventions in Healthy Individuals and Individuals With COPD
The purpose of the study is to investigate the effect of different blood flow restriction (BFR) interventions on muscle function and adaptations both in healthy well-trained individuals and individuals diagnosed with COPD.
- Trial name
- NCT05734534
- Testing
- BFR during training, BFR during rest
- Where
- Denmark
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Morten Hostrup, PhD
Childhood Obesity, Childhood Obstructive Sleep Apnea
Co-existent Obstructive Sleep Apnea (OSA) and Obesity: Finding Non-exercise Activity Thermogenesis (NEAT) Targets for Intervention
Rationale: Obesity is an increasing childhood epidemic in Canada. Obstructive sleep apnea (OSA) is a complication of obesity which causes cardiovascular disease, reduced quality of life, and premature death.
- Trial name
- NCT00854334
- Where
- Canada
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Katz, Sherri Lynne, M.D.
Virtual Reality, Stress
VR Embodiment for Stress Evaluation in a Return to Work Simulation
Comparing the emotional effect of two different versions of one VR experience. The VR experience will simulate a typical return to work situation after an absence due to burnout.
- Conditions
- Virtual Reality, Stress, Burnout
- Trial name
- VRSTEVAR (NCT05379764)
- Testing
- Embodiment, Observation
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Clinique Saint-Jean, Bruxelles
Depression
Personalized Depression Treatment Supported by Mobile Sensor Analytics
The current best practice guidelines for treating depression call for close monitoring of patients, and periodically adjusting treatment as needed.
- Trial name
- DepWatch (NCT06292221)
- Testing
- A mobile Health (mHealth) tool called 'DepWatch'
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- UConn Health
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