Clinical trials: Symptoms and Signs
Postherpetic Neuralgia ( PHN ), Ultrasound Guided, Block, Ultrasound Guided Injection
Effectiveness of Ultrasonography-Guided Serratus Posterior Superior Intercostal Plane Block in Thoracic Postherpetic Neuralgia: A Retrospective Cohort Study
Postherpetic neuralgia (PHN) is a chronic pain syndrome that can be resistant to treatment, leading to physical and social disability, psychological disturbances, and potentially persisting for years .
- Trial name
- pain (NCT07067892)
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Hypertension
Effects of Combined High Intensity Interval Training and Resistance Training
Background: Hypertension has long been considered as a major risk factor for cardiovascular disease representing a high public health concern.
- Trial name
- Hypertension (NCT06845436)
- Testing
- Exercise, routine physical activity
- Where
- Saudi Arabia
- Volunteers
- 60 people
- Sponsor
- Prince Sattam Bin Abdulaziz University
Iron-deficiency, Iron Deficiency Anemia
Iron Metabolism Disorders in Patients With Sepsis or Septic Shock.
Anemia is a common health problem. Depending on a geographical region, anemia affects even 50% of population. Among patients admitted to the intensive care unit (ICU) anemia may affect as much as 66% of patients.
- Conditions
- Iron-deficiency, Iron Deficiency Anemia, Anemia of Chronic Disease, Sepsis
- Trial name
- NCT05217836
- Testing
- ferritin; iron; transferrin; transferrin saturation; hemoglobin in reticulocyte; hepcidin
- Where
- Poland
- Volunteers
- 90 people
- Sponsor
- Medical University of Silesia
Postherpetic Neuralgia
A Crossover Study to Evaluate the Safety, Tolerability and Efficacy of XPF-002 in Subjects With Postherpetic Neuralgia (PHN)
The purpose of this trial is to determine if XPF-002 is safe and effective for the treatment of pain in subjects with Postherpetic Neuralgia
- Trial name
- XEN402 (NCT01195636)
- Testing
- XPF-002
- Where
- 24 sites in United States
- Volunteers
- 70 people
- Sponsor
- Xenon Pharmaceuticals Inc.
Kidney Stones, Nephrolithiasis
6.3Fr Versus 7.5Fr Mini-Flexible Ureteroscopy for Renal Stones (MINI-FURS)
This prospective, randomized, single-blinded, non-inferiority clinical trial will compare the clinical outcomes and cost-effectiveness of two mini-flexible ureteroscopes (6.3Fr and 7.5Fr) used during flexible ureteroscopy for the…
- Conditions
- Kidney Stones, Nephrolithiasis, Renal Calculi
- Trial name
- MINI-FURS (NCT07798336)
- Testing
- 6.3Fr Mini-Flexible Ureteroscope, 7.5Fr Mini-Flexible Ureteroscope
- Where
- Canada
- Volunteers
- 308 people
- Sponsor
- Sault Area Hospital
Pediatric Obesity
Childhood Obesity Microbiome Study
The purpose of this study is to measure the effectiveness of a microbiome diet using direct food provision on dietary quality and microbiome composition among children with obesity.
- Trial name
- CHOICE (NCT04770311)
- Testing
- Microbiome friendly diet
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Duke University
Hepatitis C, Chronic
Grazoprevir (MK-5172) Administered With Peginterferon and Ribavirin in Treatment-Naïve Participants With Chronic Hepatitis C (MK-5172-003)
This study will evaluate the safety, tolerability, and antiviral activity of grazoprevir (MK-5172) when administered in combination with peginterferon alfa-2b (Peg-IFN) and ribavirin (RBV) in treatment-naïve (TN) participants…
- Trial name
- NCT01353911
- Testing
- Grazoprevir, Boceprevir, Peg-interferon alfa-2b
- Volunteers
- 368 people
- Sponsor
- Merck Sharp & Dohme LLC
Morbid Obesity
A Study of Clinical Outcomes of the REALIZE Adjustable Gastric Band-C
The purpose of this study is to evaluate the results patients are obtaining with the Realize™ Adjustable Gastric Band-C during the first 24 months after surgery.
- Trial name
- NCT00999661
- Where
- 7 sites in United States
- Volunteers
- 231 people
- Sponsor
- Ethicon Endo-Surgery
Intermittent Claudication
Invasive Revascularization or Not in Intermittent Claudication
Peripheral arterial disease (PAD) often causes exertion pain in the legs, intermittent claudication (CI) affecting> 10% of individuals> 65 years.
- Trial name
- IRONIC (NCT01219842)
- Testing
- INVASIVE (INV) treatment, Best medical treatment (BMT)
- Where
- Sweden
- Volunteers
- 159 people
- Sponsor
- Sahlgrenska University Hospital
Obesity
Multi-site Trial Using SMS to Improve Infant Weight
The goals of this multi-site clinical trial are to pilot test weekly SMS sent to parents/caregivers of infants to improve feeding practices and decrease excessive weight gain in infants who are participants of the Women, Infants…
- Trial name
- SMS (NCT02903186)
- Testing
- SMS
- Where
- 2 sites in United States, Puerto Rico
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- University of Puerto Rico
Cancer
To Assess the Interaction Between Sunitinib and Ketoconazole to Reduce the Dose and Cost of Sunitinib
Sunitinib is an ATP competitive tyrosine kinase inhibitor of several membrane receptors including VEGFR-1, -2, and -3, PDGFR-α and -β, c-KIT, CSF-1R, FLT-3, and RET.
- Trial name
- NCT01548170
- Testing
- Sunitinib, Sunitinib and Ketoconazol, Sunitiinb and Ketoconazol
- Where
- Spain
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal
Obesity
Hypoxic Training in Obese Patients
By analyzing energetic and biomechanical basis of walking, and the subsequent changes induced by hypoxic vs normoxic training in obese individuals, it may optimize the use of walking in hypoxia to gain perspective for exercise…
- Trial name
- HYPOBESE (NCT02241473)
- Testing
- Training
- Where
- Switzerland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Lausanne
Migraine Headache
Study in Participants With Acute Migraines Headaches
This is a Phase 2, multicenter, randomized, double-blind, placebo and active comparator-controlled study of LY2590443 in approximately 200 participants with migraines.
- Trial name
- NCT00804973
- Testing
- LY2590443, Sumatriptan
- Where
- 19 sites in United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Obesity, Overweight
The Effect of Different Macronutrients on Ileal Brake Activation
The purpose of this study is to determine whether ileal infusion of casein and sucrose can activate the ileal brake.
- Trial name
- NCT01509469
- Testing
- Casein, Sucrose, Saline
- Where
- Netherlands
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Paroxysmal Atrial Fibrillation, Persistent Atrial Fibrillation
Combined Study of ATrial Strain and Voltage by High Density Mapping in Young Patients With Atrial Fibrillation.
Atrial The treatment of atrial fibrillation (AF) includes 2 axes: the prevention of the cardio-embolic risk and rhythm control. The possibilities for this control are antiarrhythmic drugs and, above all, catheter ablation, an…
- Conditions
- Paroxysmal Atrial Fibrillation, Persistent Atrial Fibrillation, Catheter Ablation, Atrial Cardiomyopathy
- Trial name
- CATS-AF (NCT05565183)
- Testing
- MRI (with injection of contrast product)
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Urothelial Carcinoma (UC), HER2
Artificial Intelligence-assisted HER2 Expression Assessment in Urothelial Carcinoma Based on Imaging-pathology Omics
This study aims to build upon previous research by using artificial intelligence methods to fuse multimodal data from imaging and pathology to construct a predictive model for HER2 expression in urothelial carcinoma.
- Conditions
- Urothelial Carcinoma (UC), HER2, Diagnostic
- Trial name
- NCT07454941
- Where
- China
- Volunteers
- 4,000 people
- Sponsor
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Weight Gain
Efficacy of Olanzapine on Weight Gain in Advanced Gynecologic Cancer with Paclitaxel and Carboplatin: a Double Blind, Placebo-controlled Randomized Trial
Efficacy of olanzapine on weight gain in advanced stage gynecologic cancer Proprotion of pateints in advanced stage gynecologic cancer who recieving paclitaxel and carboplatin chemotherapy gain weight on olanzapine or placebo
- Trial name
- NCT06288854
- Testing
- weight gain each group
- Where
- Thailand
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Department of Medical Services Ministry of Public Health of Thailand
Upper Gastrointestinal Bleeding
Usefulness of Metoclopramide to Improve Endoscopic Visualization in Upper Gastrointestinal Bleeding
A prospective, randomized, double-blind study will be conducted, including all patients with upper gastrointestinal bleeding, defined as vomiting blood or black bowel movements, within 24 hours prior to admission.
- Trial name
- NCT06297954
- Testing
- Metoclopramide
- Where
- Mexico
- Volunteers
- 50 people
- Sponsor
- Universidad Autonoma de Nuevo Leon
Dilated Cardiomyopathies, Idiopathic, Heart Failure, Systolic
Pulse Reduction On Beta-blocker and Ivabradine Therapy
Heart failure with reduced left ventricular ejection fraction (HFrEF) is the most common form of chronic heart failure in subjects ≤ 75 years of age.
- Conditions
- Dilated Cardiomyopathies, Idiopathic, Heart Failure, Systolic, Ventricular Remodeling, Electrical Remodeling
- Trial name
- PROBE-IT (NCT02973594)
- Testing
- Ivabradine
- Where
- 2 sites in United States
- Volunteers
- 28 people
- Sponsor
- University of Colorado, Denver
Ulcer Foot, Chronic Skin Ulcer
Platelet Rich Plasma (PRP) Bio Stimulant Gel Dressing in Treating Chronic Non Healing Leg and Foot Ulcers: Cost and Effectiveness
Background Chronic non-healing ulcer is a common problem met in clinical practice and represents a burden to the patients. Chronic ulcer lacks growth factors (GFs) to promote the healing process and is frequently followed by…
- Conditions
- Ulcer Foot, Chronic Skin Ulcer, Non-Healing Ulcer of Skin
- Trial name
- NCT04065594
- Testing
- PRP dressing, conventional ordinary dressing
- Where
- Egypt
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Zagazig University
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