Clinical trials: T2D
Type 2 Diabetes (T2DM)
Investigation of the Effect of Intrinsic Foot Muscle Training on Plantar Pressure Distribution in Individuals With Type 2 Diabetes Mellitus
The goal of this experimental randomized controlled study is to evaluate the effectiveness of the exercise program to be applied to prevent foot wounds, which is one of the leading foot problems that develop as a result of…
- Trial name
- NCT05974020
- Testing
- Control, Intrinsic Muscle Training, Aerobic Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Diabetes Mellitus, Type 2. Physiology of Glucose Kinetics
Glucose Kinetics After Wheat and Rye Breads
Certain functional properties of cereal products, e.g. their postprandial glucose and insulin responses, have been characterized as steps towards obtaining a greater understanding of their beneficial health effects.
- Trial name
- NCT03581266
- Testing
- Rye/Wheat
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Swedish University of Agricultural Sciences
Type 2 Diabetes Mellitus
The Verona Newly Diagnosed Type 2 Diabetes Study
Type 2 diabetes mellitus is a complex disease whose clinical phenotype results from the variable combination of genetic and nongenetic factors.
- Trial name
- VNDS (NCT01526720)
- Where
- Italy
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Universita di Verona
Diabetes Mellitus, Type 2
Study to Understand the Genetics of the Acute Response to Metformin and Glipizide in Humans
The SUGAR-MGH investigators are studying the influence of inherited gene variants on the response to two commonly prescribed type 2 diabetes medications, metformin and glipizide.
- Trial name
- SUGAR-MGH (NCT01762046)
- Testing
- Glipizide, Metformin, Oral Glucose Tolerance Test
- Where
- 3 sites in United States
- Volunteers
- 1,033 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Diabetes Mellitus, Type 2, Glucose Intolerance
The Effects of Light on Glucose Metabolism
This study evaluates the effect of bright light on postprandial blood glucose metabolism in obese subjects with impaired fasting glucose and/or impaired glucose tolerance.
- Conditions
- Diabetes Mellitus, Type 2, Glucose Intolerance, Prediabetic State
- Trial name
- NCT03829982
- Testing
- Exposure to bright light during the day, Exposure to dim light during the day
- Where
- Netherlands
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Maastricht University
Type 2 Diabetes Mellitus
A Study to Evaluate Safety and Pharmacokinetics/Pharmacodynamics of Sustained Release(SR) Exenatide
The purpose of this study is to evaluate the safety, pharmacokinetics, and pharmacodynamics of SR exenatide (PT302) in healthy subjects.
- Trial name
- NCT00964262
- Testing
- SR Exenatide (PT302)
- Where
- South Korea
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Peptron, Inc.
Type 2 Diabetes Mellitus
ET-blockade and Exercise Induced Blood Flow in T2DM
The purpose of this study is to establish the effect of ET blockade on the acute exercise induced blood flow and endothelial function in subjects with T2DM.
- Trial name
- NCT01779596
- Testing
- Bosentan
- Where
- Netherlands
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Diabetes Mellitus, Non-Insulin Dependent, Non-Insulin Dependent
Study of the Effects of Vitamin C on Patients With Type 2 Diabetes
Diabetes is a disease characterized by decreased sensitivity to the action on insulin to promote sugar (glucose) use and blood vessel relaxation (vasodilation) in muscle.
- Trial name
- NCT00001870
- Testing
- Acetylcholine
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Type 2 Diabetes Mellitus
Vitamin D Receptor Polymorphisms and Efficacy of Vitamin D-Fortified Yogurt Drink in Patients With Type 2 Diabetes
Study is a 12-week Double blind,controlled experiments designed to examine the possible effects of vitamin D receptor gene polymorphisms on the metabolic, inflammatory and oxidative stress markers in type 2 diabetic patients to…
- Trial name
- NCT01236846
- Testing
- Fortified Yogurt Drink, Plain Yogurt Drink
- Where
- 4 sites in Iran
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Tirang R. Neyestani
Type 2 Diabetes, Obesity
Metabolomic Analysis of Hepatic Insulin Resistance
This is a pilot study to show that it is possible to identify the specific types of fats in blood, adipose tissue, and liver tissue.
- Trial name
- NCT01833403
- Testing
- Hyperinsulinemic-euglycemic clamp
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Type 2 Diabetes Mellitus
Study of HTD4010 in Healthy Volunteers
To investigate safety and tolerability of HTD4010 after single ascending doses (SAD) in healthy volunteers
- Trial name
- NCT02538848
- Testing
- HTD4010
- Where
- Australia
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- HighTide Therapeutics (Hong Kong) Limited
Diabetes Mellitus, Obesity
Jejunal Luminal and Colonic Mucosa-Associated Microbiota in Metabolic Diseases: Methods, Identification and Causalities
This clinical study will investigate Jejunal Microbiota in Metabolic Diseases (Je-MiMe, n=45) and Colonic mucosa-associated Microbiota in Metabolic Diseases (Col-MiMe, n=45).
- Conditions
- Diabetes Mellitus, Obesity, Metabolic Disease
- Trial name
- JE/COL-MIME (NCT05186389)
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Diabetes Mellitus, Type 2
The Proportion of Patients With Non-diagnosed Diabetes Type 2
The aims of the study are to determine the prevalence of diabetes in subgroups of the population with certain characteristics (age, gender, socioeconomic status, geographical area of residence), to estimate the proportion of…
- Trial name
- Sadkorna (NCT04230382)
- Testing
- Diagnosis of diabetes (OGTT)
- Where
- Slovenia
- Volunteers
- 563 people, healthy volunteers welcome
- Sponsor
- Institute of Nutrition, Slovenia (Nutris)
Insulin Resistance, Type 2 Diabetes
Insulin Resistance in the Control of Intestinal Lipid Metabolism
America's preferential consumption of high-fat/high-sugar foods is a driving force in the current epidemic of obesity and insulin resistance.
- Trial name
- NCT02020343
- Testing
- taste tests
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Type 2 Diabetes Mellitus
Type 2 Diabetes Controlled Eating Experiment
A short-term feeding study in type 2 diabetics manipulating the fat and caloric values of meals to assess both compensation and glucose control, both covertly and overtly.
- Trial name
- NCT00198926
- Testing
- covert v overt nutrition labeling, varying meal nutrition manipulation
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Type 2 Diabetes Mellitus
A Single and Multiple-Dose Study of MK-8521 in Healthy and Obese Males (MK-8521-002)
This study will evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of MK-8521. Part 1 primary hypothesis: Administration of single subcutaneous (SC) doses of MK-8521 is sufficiently safe and well- tolerated…
- Trial name
- NCT02055547
- Testing
- MK-8521 35μg, MK-8521 100μg, MK-8521 125μg
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Diabetes Mellitus Type 2, Breast Neoplasms
AI-Based Phenome Data Analysis for Predicting the Onset of Major Diseases
This study aims to develop and validate an artificial intelligence (AI)-based predictive model to estimate the risk of incident onset of five major diseases or conditions: cardiovascular disease, type 2 diabetes mellitus, breast…
- Conditions
- Diabetes Mellitus Type 2, Breast Neoplasms, Low Back Pain, Osteoarthritis
- Trial name
- NCT07595718
- Where
- South Korea
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Jae Yong Jeon, MD
Diabetes Mellitus, Type 2
Diabetes In Sindhi Families In Nagpur (DISFIN)
The pandemic of diabetes is increasing at an alarming rate. The prevalence of diabetes has risen in India by 123% over the last decade.
- Trial name
- DISFIN (NCT03918525)
- Testing
- Sindhi families
- Where
- India
- Volunteers
- 1,462 people, healthy volunteers welcome
- Sponsor
- Lata Medical Research Foundation, Nagpur
Type 2 Diabetes
Exercise and Activity Guidance in Older Adults With Diabetes
The purpose of the project is to better understand how exercise and education will help mobility and health in older adults with diabetes.
- Trial name
- NCT00344240
- Testing
- Functional circuit training with lifestyle behavior
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Postprandial Hyperglycemia, Type 2 Diabetes
Development of Anti-Diabetic Nutraceuticals From Legume Seed Coats
This open-label clinical trial aims to evaluate whether daily consumption of soup prepared from boiled water extracts of selected legume seed coats, seasoned with salt and spices, improves glycemic regulation in individuals with…
- Conditions
- Postprandial Hyperglycemia, Type 2 Diabetes, Metabolic Syndromes
- Trial name
- NCT07688694
- Testing
- Legumes seed soup
- Where
- India
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- JSS MEDICAL COLLEGE, JSS ACADEMY OF HIGHER EDUCATION AND RESEARCH
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