Clinical trials: TACS
Major Depressive Disorder, MDD
Transcranial Alternating Current Stimulation for Major Depressive Disorder
Investigating the effects of non-invasive transcranial alternating current stimulation (tACS) on patients with Major Depressive Disorder (MDD).
- Trial name
- MDD (NCT02339285)
- Testing
- tACS (alpha), tACS (gamma)
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- University of North Carolina, Chapel Hill
Aging, Noninvasive Brain Stimulation
Memory Enhancement in Aging With Closed-Loop tACS
This project optimizes high-resolution tACS to improve memory in healthy older adults, advancing drug-free approaches for ADRD. We test stimulation schedules and develop an adaptive, brain-guided tACS system to strengthen…
- Conditions
- Aging, Noninvasive Brain Stimulation, Memory
- Trial name
- NCT07722598
- Testing
- Peak Frequency, Phase Lag, Peak Frequency + Phase Lag
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Non-suicidal Self-injury
Effects of taVNS Combined With tACS on Adolescents With Non-Suicidal Self-Injury
NSSI behavior is highly prevalent among adolescents, and its mechanisms are closely associated with attentional bias toward self-injury-related information and impulsivity, both of which may be related to reduced dlPFC activation…
- Trial name
- NCT07486804
- Testing
- 25Hz、300us transcutaneous auricular vagus nerve stimulation and10hz transcranial alternating current stimulation
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Anhui Medical University
Schizophrenia
Efficacy of tACS for Treatment of Auditory Hallucinations in Refractory Schizophrenia
The aim of this study is to evaluate the feasibility and efficacy of transcranial alternating current stimulation (tACS) as an add-on treatment for auditory hallucinations in refractory schizophrenia.
- Trial name
- NCT05282329
- Testing
- Transcranial alternating Current Stimulation (tACS)-active
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Tianjin Anding Hospital
Dysphagia, Swallowing Disorder
tACS and tRNS Studies on Brain Control of Swallowing
Transcranial alternating current stimulation (tACS) and transcranial random noise stimulation (tRNS) are two (CE marked medical devices) new, non-invasive (over the scalp) brain stimulation (NIBS) techniques.
- Trial name
- NCT04040803
- Testing
- Transcranial alternating current stimulation (tACS) and transcranial random noise stimulation (tRNS)
- Where
- United Kingdom
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of Manchester
Disorder of Consciousness
Alpha tACS for Disorders of Consciousness : a Single Case Experimental Design
BRIEF SUMMARY * (Include a statement of the study hypothesis) Avoid all personal pronouns (Limit: 5000 characters) Disorders of consciousness (DoC) following a severe traumatic brain injury represent a major medical challenge…
- Trial name
- SPARC (NCT07213869)
- Testing
- Transcranial alternating current stimulation (tACS)
- Where
- France
- Volunteers
- 5 people
- Sponsor
- Hospices Civils de Lyon
Motor Recovery
tACS for Sensory Motor Recovery After Stroke
The overall goal is to investigate the effectiveness of a novel intervention - transcranial alternating current stimulation (tACS) for motor recovery in stroke survivors.
- Trial name
- NCT06029062
- Testing
- tACS 10Hz, tACS 20Hz
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- The University of Texas Health Science Center, Houston
22Q11 Deletion Syndrome, tACS
Using Transcranial Alternating Current Stimulation to Improve Executive Function in 22q11.2 Deletion Syndrome
The purpose of this project is to explore the effects of transcranial alternating current stimulation (tACS) in children, adolescents and young adults with a 22q11.2 microdeletion.
- Trial name
- NCT05664412
- Testing
- at-home tACS using Starstim-Home tES
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- Stephan Eliez
Seizures
Boosting The Intervention Effect of Negative Memory Through tACS Stimulation
The objectives of this study include: 1) investigating the impact of negative memory substitution on an individual's other intellectual memories (i.e., neutral memories) and the underlying neurocognitive mechanisms; 2)…
- Trial name
- NCT06375395
- Testing
- Active tACS Device
- Volunteers
- 60 people
- Sponsor
- Xuanwu Hospital, Beijing
Non-suicidal Self-injury (NSSI)
Efficacy of Triple-daily 15mA tACS on Adolescent NSSI
This study aims to evaluate the clinical effectiveness of triple-daily 15 mA tACS stimulation in adolescents with Nonsuicidal Self-Injury (NSSI) by comparing the outcomes of active versus sham tACS interventions.
- Trial name
- NCT06919432
- Testing
- Active-tACS (Nexalin Technology, Inc., Houston, TX, USA)
- Where
- China
- Volunteers
- 66 people
- Sponsor
- Shanghai Mental Health Center
Alzheimer Disease
Digital Twins for Model-driven Non-invasive Electrical Brain Stimulation
The purpose of this study is to obtain preliminary data in advance of a larger clinical trial designed to test whether repeated, daily sessions of at-home transcranial alternating current stimulation (tACS) can lead to a…
- Trial name
- NEUROTWIN (NCT06826261)
- Testing
- transcranial alternating current stimulation
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- I.R.C.C.S. Fondazione Santa Lucia
Healthy
Modulating Speech Perception With Current Stimulation
This study aims to further develop tACS as a tool to improve speech perception, by manipulation of brain-speech synchronisation ("entrainment"), thereby transforming a promising approach into a technique that can benefit to…
- Trial name
- SPEECHSTIM (NCT05446350)
- Testing
- transcranial alternating current stimulation (tACS), electroencephalography (EEG), brain imaging (fMRI)
- Where
- France
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- University Hospital, Toulouse
Mild Cognitive Impairment (MCI)
Gamma tACS to Improve Cognitive Function in Mild Cognitive Impairment
Mild cognitive impairment (MCI) is a decline in memory and thinking that exceeds normal aging but does not substantially disrupt daily life, and it raises the risk of developing dementia.
- Trial name
- TACS-MCI (NCT07752316)
- Testing
- transcranial electrical stimulation
- Where
- Iran
- Volunteers
- 30 people
- Sponsor
- The National Brain Mapping Laboratory (NBML)
Schizophrenia
Transcranial Alternating Current Stimulation (tACS) for Cognitive Impairments in Patients With Schizophrenia
This trial attempts to investigate whether 10 sessions of tACS improves cognitive function, especially which domains of cognitive function are most improved and to investigate whether 10 sessions of tACS affecting brain…
- Trial name
- NCT03756610
- Testing
- Active tACS, Active boosting
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Shanghai Mental Health Center