Clinical trials: THA
Dengue
A Phase II Trial of a Live Attenuated Virus Tetravalent Dengue Vaccine in Healthy Adults in Thailand
This descriptive study will evaluate the safety and immunogenicity of different formulations of the WRAIR dengue vaccine compared to a placebo.
- Trial name
- NCT00370682
- Testing
- T-DEN F17, T-DEN F-19
- Where
- Thailand
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- U.S. Army Medical Research and Development Command
Migraine, Treatment
Facilitators and Barriers to Eptinezumab Administration in Thailand
This research study is designed as a longitudinal prospective descriptive study using mixed-method data collection. Eptinezumab, an anti-calcitonin gene-related peptide monoclonal antibody (anti-CGRP mAb), is administered by…
- Conditions
- Migraine, Treatment, Treatment Refusal
- Trial name
- FACEpi (NCT07035197)
- Testing
- Eptinezumab
- Where
- Thailand
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Malaria,Falciparum
Safety and Immunogenicity of the Malaria Vaccine, R21/MatrixM, in Healthy Thai Adults
Malaria remains one of the leading causes of morbidity and mortality worldwide. Plasmodium falciparum is a complex pathogen with numerous immune evasion mechanisms which has added layers of complexity to the development of safe…
- Trial name
- R21/Matrix-M (NCT05252845)
- Testing
- R21/Matrix-M vaccination, DHA-PIP, PQ
- Where
- Thailand
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Pharmacokinetics, Pharmacogenomics
Population Pharmacokinetics and Pharmacogenomics of Oral Oxycodone in Thai Pediatric Surgical Patients
This study is designed as an experimental trial which collect prospective data at Mahidol university. It aims to characterize the responses of Thai pediatric population,age 1 - 6 years, to oxycodone oral syrup and its metabolites…
- Conditions
- Pharmacokinetics, Pharmacogenomics, Oxycodone
- Trial name
- PedPK (NCT03145272)
- Testing
- Oxycodone
- Where
- Thailand
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Tranexamic Acid, Blood Loss, Surgical
Intravenous vs. Topical Tranexamic Acid in Revision THA (VITALITY-X)
The objective of this study is to evaluate and compare the effects of intravenous and topical administration of tranexamic acid during revision hip arthroplasty on blood loss, allogenic blood transfusion rates, length of hospital…
- Conditions
- Tranexamic Acid, Blood Loss, Surgical, Arthroplasty, Replacement, Hip
- Trial name
- VITALITY-X (NCT02938962)
- Testing
- Tranexamic Acid
- Where
- Canada
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Mount Sinai Hospital, Canada
HIV
Undetectable = Untransmissible in Thailand (888/64)
This is a cross-sectional study to assess awareness, knowledge, and implementation of the concept of U=U among Thai PLHIV and Thai HIV healthcare providers, as well as associated factors.
- Trial name
- 888/64 (NCT05195346)
- Where
- Thailand
- Volunteers
- 770 people, healthy volunteers welcome
- Sponsor
- Institute of HIV Research and Innovation Foundation, Thailand
Rabies, Healthy Volunteers
Study of Purified Vero Rabies Vaccine Compared With Two Reference Rabies Vaccines, Given in a Pre-exposure Regimen to Children and Adults and as Single Booster Dose to a Subset of Adults
The primary objective of this study is: To demonstrate the VRVg-2 is non-inferior to Verorab and Imovax Rabies vaccines in each age group (pediatric and adult populations) when administered as a 3-dose PrEP regimen, in terms of…
- Trial name
- VRV12 (NCT04127786)
- Testing
- Purified vero rabies vaccine - serum free - VRVg-2, Purified inactivated rabies vaccine - Verorab®, Purified inactivated rabies vaccine - Imovax® Rabies
- Where
- 4 sites in Thailand
- Volunteers
- 1,708 people, healthy volunteers welcome
- Sponsor
- Sanofi Pasteur, a Sanofi Company
Rice Serum, Rice Mask
Facial Serum and Mask and Ready-to-drink Jelly From Thai Rice
This study consisted of three sub-studies including 1) development and evaluation of facial serum from Thai rice on skin moisture, elasticity, oiliness, and melanin in healthy participants 2) development and evaluation of facial…
- Conditions
- Rice Serum, Rice Mask, Rice Jelly
- Trial name
- NCT06475222
- Testing
- Study 1: Facial serum with alpha albutin, Study 1: Facial serum with Tubtim Chumpae rice extract, Study 2: Facial mask with Hom Pathum rice extract
- Where
- Thailand
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Burapha University
HIV Infection, Healthy
Trends of Morbidity and Mortality Among Thai HIV-infected and HIV-uninfected Patients: a Five-year Prospective Cohort Study
1. To describe the morbidity and clinical characteristics among HIV-infected patients and HIV-uninfected patients. 2. To identify the risk factors for the complication or morbidity among HIV-infected patients and HIV-uninfected…
- Trial name
- TNT-HIV (NCT01634477)
- Where
- Thailand
- Volunteers
- 816 people, healthy volunteers welcome
- Sponsor
- Thai Red Cross AIDS Research Centre
Parkinson Disease, Idiopathic
Parkinson Disease: A Model of National Digital Interventions to Prevent or Slow a Rise of Non-Communicable
According to Parkinson's Disease Medical Center of Excellence's project which was registered Parkinson's disease patients in 2008-2011, it was found that there were more than 60,000 people with Parkinson's disease in Thailand…
- Trial name
- PDRegistry (NCT06609681)
- Where
- Thailand
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Roongrooj Bhidayasiri
Healthy
Open-Label Pharmacokinetic of Oseltamivir in Healthy Obese Thai Adult Subjects
This study is planned to characterize the pharmacokinetic properties of oseltamivir and the active product--oseltamivir carboxylate--in obesity in order to provide clinical guidance for the optimum oseltamivir treatment regimens…
- Trial name
- NCT01049763
- Testing
- oseltamivir
- Where
- Thailand
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- South East Asia Infectious Disease Clinical Research Network
Atopic Dermatitis
The Transcriptomic Study of Thai Patients With Atopic Dermatitis by Tape Strips
This study will be use the tape strip technique to evaluate the skin biomarkers of atopic dermatitis among Thai patients to differentiate clinical phenotype.
- Trial name
- NCT05598762
- Testing
- Tape strips
- Where
- Thailand
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Queen Sirikit National Institute of Child Health
Osteopenia, Vitamin D Deficiency
Bone Health and Vitamin D Status
This study will compare and assess the prevalence of osteopenia and vitamin D deficiency as well as effects of TDF on the patients' bone among HIV positive and negative patients.
- Conditions
- Osteopenia, Vitamin D Deficiency, HIV Infection
- Trial name
- BHVD (NCT01634607)
- Where
- Thailand
- Volunteers
- 235 people, healthy volunteers welcome
- Sponsor
- Thai Red Cross AIDS Research Centre
Healthy Subjects
Vildagliptin and Metformin Tablets 50/1000 mg Relative to GALVUS MET (50mg/1000 mg) Tablets
The study is to compare the rate and extent of absorption of a generic formulation with that of a reference for mulation when given as equal labeled dose.
- Trial name
- NCT06248801
- Testing
- Vildagliptin and Metformin-Test product, Vildagliptin and Metformin-Reference product
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Bio-innova Co., Ltd
THA
Fascia Iliaca Blocks for Total Hip Arthroplasty
The development of minimal-incision techniques for total hip arthroplasty (THA) with preservation of soft tissue is generally associated with reduction of postoperative pain and increased patient comfort.
- Trial name
- NCT03691337
- Testing
- Marcaine 0.25 % Injectable Solution, Sodium chloride
- Where
- Belgium
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- New York School of Regional Anesthesia
Healthy Volunteer, Dabigatran
Bioequivalence Study of Dabigatran Etexilate Capsules 150 mg in Healthy Thai Volunteers Under Fasting Conditions
The bioequivalence of Dabigatran Etexilate Capsules 150 mg to Boehringer Ingelheim's Pradaxa® will be assessed by a statistical comparison of various pharmacokinetic parameters derived from the plasma concentration-time curves of…
- Conditions
- Healthy Volunteer, Dabigatran, Bioequivalence Study
- Trial name
- NCT06441916
- Testing
- Dabigatran Etexilate Capsules 150 mg
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- International Bio service
Childhood Pneumonia, Pneumococcal Carriage
The Study of Chest Infections in Infants Living in a Refugee Camp on the Thai-Burmese Border
This study will follow 1000 refugee infants from birth for two years. The aim of the study is to better understand why some children develop infections caused by the bacterium Streptococcus pneumoniae whilst others merely carry…
- Trial name
- ARI (NCT00894764)
- Where
- 2 sites in Thailand
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University of Oxford
HIV Infections, Chlamydia Trachomatis
Safety and Acceptability of Carraguard™ Among HIV-negative Couples in Thailand
The primary aims of the study were to assess the safety and acceptability of Carraguard applied vaginally prior to sexual intercourse for six months in both women and men; and to examine several dimensions of acceptability.
- Conditions
- HIV Infections, Chlamydia Trachomatis, Nesseria Gonorrhea, Trichomonas Vaginitis
- Trial name
- NCT00213057
- Testing
- Carraguard (PC-515)
- Where
- Thailand
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Population Council
Iron Deficiency Anemia
Iron Fortified Food to Improve Japanese Encephalitis and Typhoid Fever Vaccine Immunogenicity
Iron deficiency (ID) anaemia (IDA) is a global public health problem, with the highest prevalence in Africa and in South-East Asia.
- Trial name
- NCT06027801
- Testing
- Iron-fortified cookies, Japanese encephalitis (JE) vaccine, Typhoid Vi polysaccharide (Vi-PS) vaccine
- Where
- Thailand
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Healthy Subjects
Empagliflozin 10 mg Tablets Relative to Jardiance 10 mg
The study is to compare the rate and extent of absorption of a generic formulation with that of a reference for mulation when given as equal labeled dose.
- Trial name
- NCT06232239
- Testing
- Empagliflozin-Test product, Empagliflozin-Reference product
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Bio-innova Co., Ltd