Clinical trials: THA
Brugada Syndrome
Southeast Asian Brugada Syndrome Cohort
Brugada syndrome (BrS) is the leading cause of sudden death in young Asian adults including Thailand. This syndrome may be hereditary and involve mutations in certain genes.
- Trial name
- SEA-BrS (NCT04232787)
- Where
- 11 sites in Thailand
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Depression in Adolescence
Development of Online Mindfulness-Based Intervention for Thai-Depressed Adolescents
Project: "Development of Online Mindfulness-Based Intervention for Thai-Depressed Adolescents" For this project we adopted Kabat-Zinn's definition of mindfulness as the intentional and non-judgmental awareness of thoughts…
- Trial name
- NCT06595485
- Testing
- online mindfulness based intervention
- Where
- Thailand
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- Mae Fah Luang University
Healthy Volunteer
Bioequivalence Study of Generic Leflunomide 20 mg Film-coated Tablets and Reference Product Under Fasting Conditions
This Study Aims to Assess the Relative Bioavailability, Including the Rate and Extent of Absorption, of 20 mg Leflunomide Tablets Compared to ARAVA® 20 mg Tablets.
- Trial name
- NCT06228443
- Testing
- Leflunomide 20 mg Film-coated Tablet, ARAVA® 20 mg Film-coated Tablet
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- International Bio service
Malaria, Parasitic Diseases
Malaria Elimination Pilot Study in Military Forces in Cambodia
Antimalarial drug resistance has reached critical levels on the Thai-Cambodian border. Many have begun advocating for concerted malaria elimination efforts in Cambodia.
- Trial name
- NCT02653898
- Testing
- DHA-PIP, Primaquine, Artesunate + Mefloquine
- Where
- Cambodia
- Volunteers
- 1,050 people, healthy volunteers welcome
- Sponsor
- Armed Forces Research Institute of Medical Sciences, Thailand
Hepatitis b Virus
A Study to Test the Efficacy of the HBV Vaccine and to Look at the Prevalence of HBV Infection
The prevalence of Hepatitis B core antigen in the Thai population is about 70 %, no data of isolated Hepatitis B core antigen is reported.
- Trial name
- NCT00476411
- Testing
- HBV vaccine
- Where
- Thailand
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- The HIV Netherlands Australia Thailand Research Collaboration
Osteoarthritis, Hip
Evaluation of Functional Rehabilitation in Patients Undergoing Physiotherapy After Total Hip Arthroplasty
This study aims to objectively evaluate the implications of physiotherapeutic rehabilitation in the Assistance Protocol of Total Hip Arthroplasty (THA), by assessing the motor performance and testing the quality of life of…
- Trial name
- Artrhosis (NCT01491048)
- Testing
- THA Physiotherapy, No physiotherapy after THA
- Where
- Brazil
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
PrEP Test and Treat
Evaluation of a Facility-based Test, Treat, and Prevent HIV Program Among Men Who Have Sex With Men and Transgender Women in Thailand
This is a prospective observational cohort study that aims to enroll a total of 2000 Thai MSM and TG at five health facilities in four provinces of Thailand. Each participant will be followed for 18 months.
- Trial name
- PrEP (NCT02369887)
- Where
- Thailand
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Thai Red Cross AIDS Research Centre
Pertussis, Diphtheria
Maternal Immunization With Tetanus Toxoid, Reduced Diphtheria Toxoid, Reduced-dose (2 µg) Recombinant Pertussis Vaccine (TdaP2gen) and Its Effect on the Immune Response in Thai Infants up to 15-18 Months Old
Pertussis remains a major global public health problem. In Thailand, pertussis vaccination is recommended during pregnancy at 20-32 weeks' gestation, together with routine childhood diphtheria-tetanus-pertussis vaccination…
- Conditions
- Pertussis, Diphtheria, Tetanus, Vaccine-Preventable Diseases
- Trial name
- M-PRIME (NCT07621341)
- Testing
- Maternal TdaP2gen vaccine, Infant Acellular Pertussis-containing Vaccine, Infant Whole-cell Pertussis-containing Vaccine
- Where
- Thailand
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Chiang Mai University
Surgery
QL vs LP Blocks for Analgesia Following THA
Purpose: Evaluate difference in postoperative opioid consumption when subjects receive a quadratus lumborum (QL) or lumbar plexus (LP) block preoperatively for total hip arthroplasty (THA).
- Trial name
- NCT04402437
- Testing
- LP Block, QL Block
- Where
- United States
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Vitamin A Status
Efficacy of Vitamin A Fortified Rice in Lactating Thai Women
Vitamin A deficiency (VAD) remains a public health problem that occurs in children and women. WHO estimates that 190 million preschool age children (under five years of age) and 19.1 million pregnant women have inadequate…
- Trial name
- EVAL (NCT03056625)
- Testing
- Vitamin A fortified rice, Normal rice
- Where
- Thailand
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Prince of Songkla University
Pre-Exposure Prophylaxis
Developing mHealth to Promote PrEP Use Among Thai Young Vulnerable Adolescents and Emerging Adults
The main aim of this study is to develop technology-based interventions to improve HIV pre-exposure prophylaxis (PrEP) uptake and adherence among Thai young transgender women.
- Trial name
- NCT05262426
- Testing
- Behavioral: Motivational Enhancement System for PrEP Uptake and Adherence (MES-PrEP), Enhanced YaCool, Standard PrEP Counseling
- Where
- 3 sites in Thailand
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester
Intimate Partner Violence (IPV), Social Support
Cultural Adaptation of a Web-Based App (myPlan Thailand) to Empower and Support Friends and Family of Intimate Partner Violence Survivors
This research will support and empower friends/family (F/F) of intimate partner violence (IPV) survivors in Thailand, where IPV is critical and common, and survivors first and foremost seek help for abuse from their F/F.
- Conditions
- Intimate Partner Violence (IPV), Social Support, Empowerment, mHealth
- Trial name
- IPV (NCT06934174)
- Testing
- WeSafe (myPlan Thailand: Friends and Family), DV learning
- Where
- Thailand
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Boromarajonani College of Nursing, Khon Kaen
HIV/AIDS, STD
Addressing the Continuum of Care Among High-risk Thai Men
Young Thai men who have sex with men (YMSM) are at high risk for HIV. However, the Thailand National HIV Strategy does not adequately cover HIV prevention for YMSM using specific methods relevant to them, and instead uses a…
- Trial name
- NCT05161689
- Testing
- HUG-M+
- Where
- 2 sites in Thailand
- Volunteers
- 636 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Coxarthritis
Direct Anterior Approach (DAA) for Total Hip Arthroplasty (THA): Capsular Resection Versus Capsular Flap Retention
Direct Anterior Approach (DAA) for Total Hip Arthroplasty (THA): Capsular resection versus capsular flap retention. Prospective study design comparing clinical data in randomized THA patients who either had capsular resection or…
- Trial name
- NCT02970253
- Testing
- Capsular resection, Capsular retention
- Where
- Belgium
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- ZOL
HPV Testing
Study on Anal Human Papillomavirus Infection and Anal Intraepithelial Neoplasia Among Men Who Have Sex With Men in Indonesia, Malaysia, and Thailand
OBJECTIVES 1. To determine the prevalence and incidence of anal HPV infection, including infection with high-risk HPV types, among MSM in Indonesia, Malaysia, and Thailand. 2.
- Trial name
- NCT02155231
- Where
- Thailand
- Volunteers
- 430 people, healthy volunteers welcome
- Sponsor
- Thai Red Cross AIDS Research Centre
Encephalitis, Japanese Encephalitis
A Study of Japanese Encephalitis Chimeric Virus Vaccine Compared With SA14-14-2 Vaccine in Infants and Toddlers
The purpose of this study is to compare a single dose of Japanese encephalitis (JE) chimeric virus vaccine (JE-CV) with a single dose of SA14-14-2 live vaccine as primary vaccination in infants and toddlers.
- Trial name
- NCT01092507
- Testing
- Japanese encephalitis chimeric virus vaccine (JE-CV), Japanese encephalitis live vaccine (SA14-14-2 vaccine) (CD.JEVAX®)
- Where
- 3 sites in Thailand
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Sanofi Pasteur, a Sanofi Company
Iron Deficiency Anemia
Iron Fortified Food to Improve Japanese Encephalitis and Typhoid Fever Vaccine Immunogenicity
Iron deficiency (ID) anaemia (IDA) is a global public health problem, with the highest prevalence in Africa and in South-East Asia.
- Trial name
- NCT06027801
- Testing
- Iron-fortified cookies, Japanese encephalitis (JE) vaccine, Typhoid Vi polysaccharide (Vi-PS) vaccine
- Where
- Thailand
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Genetic Predisposition to Disease, Breathing, Mouth
Expression of Genes Relating Hypertension and Efficacy of 4-7-8 Breathing Control on Reducing Blood Pressure
This study consists of two sub-studies. Study 1 investigates gene expression related to the development of hypertension in Thailand, and Study 2 examines the effectiveness of the 4-7-8 breathing technique in reducing blood…
- Trial name
- NCT07018128
- Testing
- Study 2: deep breathing, Study 2: 4-7-8 breathing, Study 2: slow breathing with device
- Where
- Thailand
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- Burapha University
Osteoarthritis, Hip, Avascular Necrosis of Hip
ROSA® Hip System THA PMCF
This study is a Prospective, Multicenter, Single-Arm, Cohort post-market study to evaluate the accuracy of acetabular implant position using the robotic-arm surgical assistant (ROSA® Hip System).
- Trial name
- NCT05497206
- Testing
- One of the following hip implants may be used within this arm of the study: G7 Acetabular System, Taperloc Complete System, Avenir and Avenir Complete Systems, and Echo Bi-Metric System
- Where
- 2 sites in United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Zimmer Biomet
HIV Infections
Safety Study of UC-781 Vaginal Microbicide
This study will help determine whether UC-781 gel is safe when applied to the vagina twice daily for 14 days, and will assess whether women and men find the gel acceptable to use.
- Trial name
- NCT00446979
- Testing
- UC 781
- Where
- Thailand
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention