Clinical trials: TKA Outcomes
Osteoarthritis, RheumatoId Arthritis
Zimmer POLAR - Total Knee Arthroplasty (TKA)
The primary objective of this study is to obtain implant survivorship and clinical outcomes data for commercially available Persona fixed bearing knee implants used in total knee arthroplasty.
- Conditions
- Osteoarthritis, RheumatoId Arthritis, Traumatic Arthritis, Polyarthritis
- Trial name
- NCT01859130
- Testing
- Zimmer Persona Total Knee System
- Where
- 4 sites in United States
- Volunteers
- 299 people
- Sponsor
- Zimmer Biomet
Osteoarthritis, Knee
Stryker Triathlon® Cruciate Substituting vs. Posterior Stabilized Outcomes Study
This study compares the clinical and radiographic outcomes obtained with the use of the Stryker Triathalon® Cruciate Substituting (CS) and Posterior Stabilized (PS) tibial inserts.
- Trial name
- NCT01367925
- Testing
- Stryker Triathlon® CS Tibial Insert, Stryker Triathlon® PS Tibial Insert
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Spokane Joint Replacement Center
Total Knee Anthroplasty, Robotic Surgery
Early Clinical and Radiological Outcomes of a Novel Robotic TKA System
This study aimed to evaluate the early clinical and radiological outcomes of robot assisted total knee arthroplasty, and to determine the efficiency and safety of its bone resection and implant positioning of the novel robot…
- Trial name
- RA-TKA (NCT06638047)
- Testing
- robotic-assisted TKA, CI-TKA
- Where
- China
- Volunteers
- 144 people
- Sponsor
- Peking University Third Hospital
Osteoarthritis Arthritis, Joint Disease
RSA RCT: Attune RP TKA Versus LCS RP TKA
The LCS Complete Cementless Knee by DePuy Synthes is a rotating platform knee replacement with a good clinical track record and good survival rates.
- Conditions
- Osteoarthritis Arthritis, Joint Disease, Musculoskeletal Disease
- Trial name
- ALKNEE (NCT03101007)
- Testing
- ATTUNE Knee Prosthesis by DePuy, LCS Knee Prosthesis by DePuy
- Where
- 2 sites in Netherlands
- Volunteers
- 61 people
- Sponsor
- Spaarne Gasthuis
Pain, Postoperative, Osteoarthritis, Knee / Osteoarthritis, Hip
iPACK Block vs. Periarticular Infiltration for TKA Pain Control
This study aims to retrospectively compare two different multimodal analgesic techniques for pain management after total knee arthroplasty (TKA).
- Trial name
- NCT07267650
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Turgutlu State Hospital
Osteoarthritis
Prospective Clinical Study Evaluating Tibiofemoral Rotational Alignment Using Intraoperative Sensing During Total Knee Arthroplasty (TKA)
The objectives of the study are twofold: 1) Evaluate how intra-operative sensing may assist the surgeon with tibiofemoral rotational alignment by testing the precision and variability of setting tray rotation to the mid-third of…
- Trial name
- NCT02286739
- Testing
- TKA with "Verasense", TKA without "Verasense"
- Where
- 6 sites in United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Orthosensor, Inc.
Arthroplasty, Replacement, Knee, Arthroplasty, Replacement, Hip
Improvement of Patient Satisfaction and Overall Outcomes Using HealthLoop
The purpose of this study is to assess the usefulness and results of orthopedic patients having access to a cell phone App called HealthLoop to utilize during the postoperative time period, compared to patients who have the usual…
- Trial name
- NCT03481595
- Testing
- HealthLoop mobile application
- Where
- United States
- Volunteers
- 294 people
- Sponsor
- The Cleveland Clinic
Satisfaction, Patient
The Outcomes of Subject After Total Knee Arthroplasty
Total Knee Arthroplasty (TKA) is a standard of intervention for severe knee osteoarthritis, also been proven with benefits in improving pain, mobility, and quality of life. However, the outcomes after TKA is controversial.
- Trial name
- NCT05810090
- Testing
- Total knee arthroplasty
- Where
- Taiwan
- Volunteers
- 631 people
- Sponsor
- Changhua Christian Hospital
Knee Arthropathy
Effect of Pre-op Patient Education on Functional Outcomes After TKA
This study aims to evaluate the effect of preoperative patient education program on functional mobility, gait, postural control, and kinesiophobia level in subjects with TKA.
- Trial name
- NCT03230942
- Testing
- Pre-operative education, Pos-operative rehabilitation
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- University of the State of Santa Catarina
Knee Osteoarthritis
ROM Outcomes in Patients Undergoing a Primary TKA
The goal of this prospective, randomized study is to compare the outcomes of patients undergoing primary TKA after photographing final knee range of motion immediately post-operatively and sharing these photographs with patients…
- Trial name
- NCT04217486
- Testing
- Patient will be shown a photograph of their knee at 2 weeks postop, Patient will not be shown a photograph of their knee at 2 weeks postop
- Where
- United States
- Volunteers
- 158 people
- Sponsor
- University of Louisville
Osteoarthritis (OA) of the Knee, Knee Pain Arthritis
Imageless Navigation Versus Image-Based Navigation in Robotic-Assisted Total Knee Arthroplasty for Knee Osteoarthritis
The goal of this clinical trial is to learn if imageless navigation is not inferior to image-based navigation in robotic-assisted total knee arthroplasty (RA-TKA) for treating patients with knee osteoarthritis.
- Conditions
- Osteoarthritis (OA) of the Knee, Knee Pain Arthritis, Total Knee Arthroplasty (TKA), Robotic Assisted Arthroplasty
- Trial name
- NCT07522489
- Testing
- Imageless Robotic-Assisted Total Knee Arthroplasty, Image-based Robotic-Assisted Total Knee Arthroplasty
- Where
- Poland
- Volunteers
- 146 people
- Sponsor
- Medical University of Warsaw
Total Knee Arthroplasty
Can the Use of Virtual Reality Improve TKA Outcomes
Virtual reality (VR) uses computer technology to create a three-dimensional environment which the user can explore and interact with.
- Trial name
- VR-TKA (NCT06962046)
- Testing
- Virtual Reality
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- Belfast Health and Social Care Trust
Catastrophization
Preoperative Cognitive Therapy for Improving Health Outcomes After TKA in High-risk Catastrophizing Subjects
The investigators propose a randomized controlled trial to evaluate the effects of treatment intended to reduce pain catastrophizing among patients reporting high pain catastrophizing prior to total knee replacement(TKR), total…
- Trial name
- CT_TKA (NCT01772329)
- Testing
- Cognitive Therapy, Routine Care
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Total Knee Replacement
Robotic Assisted TKA
As an intraoperative tool, a modern robotic total knee arthroplasty (TKA) system should be able to identify a patient's native femoral and tibial anatomy, as well as, assess ligament tension and gap balance.
- Trial name
- NCT06062615
- Testing
- Total knee replacement using Omnibot Knee System, Conventional Total knee replacement, Omnibot Robotic Knee System
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Rothman Institute Orthopaedics
Knee Osteoarthritis, Total Knee Arthroplasty
Robotic-Assisted Total Knee Arthroplasty: Cruciate-Retaining Versus Bi-Cruciate Stabilized
The global prevalence of osteoarthritis of the knee with total knee arthroplasty performed is projected to substantially rise in the near future.
- Trial name
- NCT06838663
- Testing
- Robotic assisted Cruciate-Retaining (CR) TKA procedures, Robotic assisted Bi-Cruciate Stabilized (BCS) TKA procedures
- Where
- Hong Kong
- Volunteers
- 60 people
- Sponsor
- Chinese University of Hong Kong
Osteoarthritis, Knee
JOURNEY™ II CR Total Knee System
The purpose of this study is to evaluate the safety and effectiveness of the JOURNEY™ II CR Total Knee System in subjects with degenerative joint disease (DJD) requiring primary total knee replacement.
- Trial name
- NCT02440672
- Testing
- JOURNEY™ II CR Total Knee System (J II CR TKS)
- Where
- 9 sites in United States, Spain and 1 more
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Smith & Nephew, Inc.
Osteoarthritis
Outcomes Following Total Knee Arthroplasty
The purpose of this investigation is to determine both patient-reported and performance-based outcomes, specifically muscle function and kinematic/kinetic outcomes, between four different surgical total knee prostheses in…
- Trial name
- NCT02364011
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Utah
Knee Osteoarthritis, Total Knee Arthroplasty
Prediction of Postoperative Outcomes After TKA Using Instrumented Insoles and DNN
This multicenter prospective observational study aims to evaluate whether preoperative clinical variables and wearable sensor-derived gait features can predict postoperative improvement after total knee arthroplasty (TKA).
- Trial name
- NCT07367789
- Testing
- Instrumented Insole Gait Assessment
- Where
- South Korea
- Volunteers
- 200 people
- Sponsor
- Yonsei University
Osteoarthritis, Knee
Effects of Perioperative Intravenous Dexamethasone in Clinical Outcomes After Total Knee Arthroplasty in a Hispanic Population
The purpose of this study is to evaluate the efficacy of an intravenous (IV) perioperative dexamethasone regime in the clinical outcomes after a robotic-assisted Total Knee Arthroplasty (TKA) in a Hispanic population.
- Trial name
- NCT06042426
- Testing
- Dexamethasone, Morphine, Oxycodone and acetaminophen
- Where
- Puerto Rico
- Volunteers
- 100 people
- Sponsor
- University of Puerto Rico
Osteoarthritis, Knee, Osteoarthritis, Hip
Impact of a POPOP on Preoperative Health, Eligibility, and Clinical & Patient-Reported Outcomes in TJA
In this pilot study, we will test the hypothesis that a POPOP for currently ineligible UAMS orthopedic surgery patients wanting hip or knee replacement improves markers of preoperative health, ability to reach a BMI threshold <40…
- Conditions
- Osteoarthritis, Knee, Osteoarthritis, Hip, Avascular Necrosis, Rheumatoid Arthritis
- Trial name
- NCT04910048
- Testing
- POPOP (preoperative patient optimization program), SOC (standard of care)
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- University of Arkansas