Clinical trials: TKA Outcomes
Tantalum, Bone Loss
Allograft and Tantalum Cone Reconstruction in TKA Revision
A new surgical technique of reconstruction for bone loss in TKA revision using tantalum cone and allograft. Study of radiological and clinical outcomes.
- Conditions
- Tantalum, Bone Loss, Allograft
- Trial name
- NCT05510011
- Where
- France
- Volunteers
- 76 people
- Sponsor
- University Hospital, Montpellier
Osteoarthritis Arthritis, Joint Diseases
RSA RCT: ATTUNE™ TKA Versus PFC Sigma TKA
The PFC Sigma Knee by DePuy Synthes is an excellent knee replacement with an excellent clinical track record, good survival rates (98% 10 years survival in patients aged < 55 years)(Keenan et al., 2012) and minimal early…
- Conditions
- Osteoarthritis Arthritis, Joint Diseases, Musculoskeletal Diseases, Rheumatic Diseases
- Trial name
- APKnee (NCT02256098)
- Testing
- ATTUNE™ Knee Prosthesis by DePuy, PFC Sigma Knee Prosthesis by DePuy
- Where
- 2 sites in Netherlands
- Volunteers
- 74 people
- Sponsor
- Leiden University Medical Center
Osteoarthritis Arthritis, Joint Disease
RSA-RCT: Attune S+ TKA Versus Sigma TKA
The PFC Sigma Knee by DePuy Synthes is an excellent knee replacement with an excellent clinical track record, good survival rates (98% 10 years survival in patients aged < 55 years) and minimal early migration as measured with…
- Conditions
- Osteoarthritis Arthritis, Joint Disease, Musculoskeletal Disease, Rheumatic Diseases
- Trial name
- APKnee2-S+ (NCT04037735)
- Testing
- ATTUNE S+ Knee Prosthesis by DePuy, PFC Sigma Knee Prosthesis by DePuy
- Where
- Netherlands
- Volunteers
- 64 people
- Sponsor
- Peter den Hollander
Knee Osteoarthritis
Comparison of Functional Outcomes of Three Surgical Approaches in Knee Arthroplasty
A functional outcomes comparison study of three surgical techniques using minimally invasive surgery mini-incision (MIS) for total knee arthroplasty (TKA), standard para-patellar TKA and the unicompartmental knee arthroplasty…
- Trial name
- NCT00983762
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Total Knee Arthroplasty
Comparison Between Brainlab Knee 3 Computer-assisted Navigation Systems and Conventional Instruments in TKA: a Prospective Cohort Study.
This is a a prospective cohort study. According to the inclusion criteria, volunteers were recruited from patients undergoing total knee arthroplasty.
- Trial name
- NCT04960345
- Testing
- Brainlab Knee 3
- Volunteers
- 188 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Arthroplasty, Arthroplasty Replacement, Knee
oneKNEE - Prospective, Non-interventional, Multicenter PMCF-Study
Safety and Clinical Performance in terms of clinical outcome of oneKNEE® (total knee arthroplasty TKA), evaluated 2 years after implantation.
- Conditions
- Arthroplasty, Arthroplasty Replacement, Knee, Prosthetic Joint Infections of Knee, TKA Outcomes
- Trial name
- oneKNEE (NCT07682909)
- Testing
- oneKNEE®
- Volunteers
- 1,020 people
- Sponsor
- Aesculap AG
Knee Osteoarthritis
Cemented vs Cementless TKA
The purpose of this study is to compare cemented and cementless versions of the Triathlon total knee arthroplasty/replacement (TKA) in terms of clinical outcomes, perioperative course, and outcome scores including function and…
- Trial name
- NCT03683992
- Testing
- Triathlon total knee system
- Where
- United States
- Volunteers
- 147 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Osteoarthritis, Knee, TKA
Comparing Efficacy Between Restricted Kinematic Alignment vs Mechanical Alignment in Bilateral TKA
The goal of this RCT is to investigate efficacy between restricted kinematic alignment and mechanical alignment TKA in simultaneous bilateral TKA patients.
- Trial name
- NCT06323577
- Testing
- Restricted kinematic alignment, Mechanical alignment
- Where
- Thailand
- Volunteers
- 50 people
- Sponsor
- Thammasat University Hospital
Knee Injuries
Evaluation of Patient Reported Outcomes (PRO) After Total Knee Arthroplasty (TKA) Under Spinal Anesthesia
The purpose of this study will be to evaluate and compare patients undergoing total knee arthroplasty (TKA) with sensor guidance versus that of a standard technique.
- Trial name
- NCT03053453
- Testing
- Spinal Surgery, Verasense Knee System device
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- NYU Langone Health
Total Knee Arthroplasty, Robotic
Early Radiographic and Clinical Outcomes of Robotic-Arm-Assisted Versus Conventional TKA
Purpose: A robotic system was recently introduced to improve prosthetic alignment during total knee arthroplasty (TKA). The purpose of this multicenter prospective randomized controlled trial (RCT) study was to determine whether…
- Trial name
- TKA (NCT05987839)
- Testing
- robotic system
- Where
- China
- Volunteers
- 130 people
- Sponsor
- Peking University Third Hospital
Knee Pain Chronic, Osteoarthritis
Persona Total Knee Arthroplasty Outcomes Study
The primary objective of this study is to obtain implant survivorship and clinical outcomes data for commercially available Persona fixed bearing knee implants used in total knee arthroplasty.
- Conditions
- Knee Pain Chronic, Osteoarthritis, Rheumatoid Arthritis, Traumatic Arthritis
- Trial name
- NCT02255383
- Testing
- Zimmer Persona Total Knee System
- Where
- 14 sites in United States
- Volunteers
- 737 people
- Sponsor
- Zimmer Biomet
Obesity, Osteoarthritis
Attune With TruMatch TM Personalized Solutions Instruments
The purpose of our study is to determine, using a prospective, randomized-controlled trial, the economic viability and clinical outcomes associated with patient-specific instrumentation (PSI) for total knee arthroplasty in an…
- Trial name
- NCT02177227
- Testing
- Attune TruMatch (TM) Patient-Specific Instrumentation
- Where
- Canada
- Volunteers
- 194 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Knee Osteoarthritis
Effects of Collagen Peptide Supplementation on Connective Tissue Remodeling, Functional Outcomes, and Wound Healing After Total Knee Arthroplasty (TKA)
Recruiting will be performed via checking the calendar for scheduled TKA procedures in the > 8 weeks by clinical staff in the UAMS orthopedic clinic.
- Trial name
- NCT05823727
- Testing
- SOLUGEL
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Arkansas
Knee Osteoarthritis, Knee Arthritis
ROMTECH PortableConnect Rehabilitation Device Usage Post Unilateral Total Knee Arthroplasty (TKA)
ROMTech is focused on transforming the healthcare market by delivering lower extremity rehabilitation systems that are effective, efficient for patient use, cost-effective, and provide better patient outcomes while simultaneously…
- Conditions
- Knee Osteoarthritis, Knee Arthritis, Knee Pain Chronic, Knee Disease
- Trial name
- NCT04497129
- Testing
- ROMTech PortableConnect, Traditional Rehabilitation and CPM Device
- Where
- 5 sites in United States
- Volunteers
- 300 people
- Sponsor
- ROM Technologies, INC
Arthroplasty, Replacement, Knee, Nerve Block
Study to Evaluate ACB Versus FNB Early Postoperative Period Functional Outcomes After TKA
The purpose of this study is to determine if patients undergoing a Total Knee Arthroplasty who receive a single shot Adductor Canal nerve block and local infiltration will have improved functional outcomes compared to individuals…
- Trial name
- ACB (NCT02218814)
- Testing
- Adductor Canal Block, Bupivacaine, Femoral Nerve Block, Bupivacaine
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- George Macrinici
Infection
Infection Prevention After TKA With or Without Vancomycin
Prospective, Randomized, Double Blinded Trial Comparing Clinical, Radiological and Laboratory Outcomes in prevention of infection after Total Knee Arthroplasty With or Without Vancomycin.
- Trial name
- TKA_Vanco (NCT05461651)
- Testing
- Knee arthroplasty
- Where
- Poland
- Volunteers
- 1,800 people, healthy volunteers welcome
- Sponsor
- Centre of Postgraduate Medical Education
Anesthesia, Regional
Adductor Canal Block (ACB) Before and After Primary Total Knee Arthroplasty (TKA)
Total knee arthroplasty (TKA) is associated with severe postoperative pain. Multimodal analgesia, including peripheral nerve block, is recommended for post-operative pain relief 1.
- Trial name
- NCT02908711
- Testing
- 0.5% ropivacaine
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Rabin Medical Center
Total Knee Anthroplasty, Postoperative Pain
Proximal Spread in Adductor Canal Block(ACB)
This prospective, randomized clinical study is designed to evaluate the effects of two different injection levels of adductor canal block (ACB) on the proximal spread of local anesthetic and clinical outcomes in patients…
- Trial name
- ACB (NCT07595471)
- Testing
- Comparison of Proximal Adductor Canal Block, Comparison True Distal Adductor Canal Block.
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- Ankara Etlik City Hospital
Knee Osteoarthritis
Trochlear Thickness and Its Effect on the Outcomes of Total Knee Arthroplasty
Total knee arthroplasty (TKA ) is the gold standard treatment for advanced knee osteoarthritis. only 85% (75% to 92%) of patients with total knee arthroplasty are satisfied with their operations and 30% develops patellofemoral…
- Trial name
- NCT06555055
- Testing
- CT trochlear thickness change
- Where
- Egypt
- Volunteers
- 87 people
- Sponsor
- Ibrahim barsoum
Arthritis Knee
Tourniquet on Total Knee Arthroplasty
The purpose of this study is determine the effect on novel pressure-regulating tourniquet use on pain, functional recovery, sleep and total blood loss following total knee arthroplasty.
- Trial name
- NCT04923724
- Testing
- tourniquet, No tourniquet
- Where
- United States
- Volunteers
- 165 people
- Sponsor
- Washington University School of Medicine