Clinical trials: TMD
Chronic Temporomandibular Disorders (TMD)
Endogenous Pain Inhibition Deficiency in Chronic TMD Pain
Temporomandibular disorders (TMDs) involve a range of conditions with varied causes, affecting a large portion of the U.S. population and posing challenges for diagnosis and management, especially in chronic cases.
- Trial name
- TMD-CPM (NCT06617494)
- Testing
- Pain modulation testing
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Temporomandibular Disorders (TMD), Temporomandibular Joint Disc Displacement, With Reduction
Long-term Follow up of TMJ Surgery and Evaluation of the 6-month Control as a Prognostic Marker.
The goal of this clinical trial is to evaluate the long-term outcome of surgical intervention (arthroscopy or discectomy) due to the diagnoses temporomandibular joint disc displacement with or without displacement.
- Conditions
- Temporomandibular Disorders (TMD), Temporomandibular Joint Disc Displacement, With Reduction, Temporomandibular Joint Disc Displacement, Without Reduction
- Trial name
- NCT06782165
- Testing
- Arthroscopy & saline irrigation alone, Discectomy
- Where
- Sweden
- Volunteers
- 91 people
- Sponsor
- Karolinska Institutet
Temporomandibular Joint Disc Displacement, Temporomandibular Joint Disc Displacement, Without Reduction
TMJ Arthroscopy Compared to Arthrocentesis in Disc Displacement Without Reduction
The goal of this clinical trial is to compare the intervention arthroscopic lysis and lavage to the intervention arthrocentesis in treating disabling and painful temporomandibular joint disc displacement without reduction.
- Conditions
- Temporomandibular Joint Disc Displacement, Temporomandibular Joint Disc Displacement, Without Reduction, Temporomandibular Disorders (TMD)
- Trial name
- ACALL (NCT06782178)
- Testing
- Arthroscopic lysis and lavage, Arthrocentesis/Saline
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Karolinska Institutet
Temporomandibular Joint Disc Displacement, With Reduction, Temporomandibular Disorders (TMD)
TMJ Arthroscopic Lysis and Lavage Compared to Operative Arthroscopy in Disc Displacement With Reduction.
The goal of this clinical trial is to compare the intervention arthroscopic lysis and lavage to the intervention operative arthroscopy in treating disabling and painful temporomandibular joint disc displacement with reduction.
- Trial name
- ALLOAA (NCT06782191)
- Testing
- Arthroscopic lysis and lavage, Operative arthroscopy
- Where
- Sweden
- Volunteers
- 96 people
- Sponsor
- Karolinska Institutet
Temporomandibular Disorders (TMD)
The Effects of Pilates Exercises on Women With Myogenic Temporomandibular Joint Dysfunction: A Randomised Controlled, Single-Blind Study
The aim of this study is to investigate the effects of an 8-week Pilates exercise program on pain, pressure-pain threshold, temporomandibular joint (TMJ) range of motion, cervical posture, stress levels, quality of life, jaw…
- Trial name
- TMD (NCT07750145)
- Testing
- Pilates, Education and home exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Toros University
Temporomandibular Disorders (TMD), Manual Therapy
Effectiveness of the Fascial Distortion Model in Temporomandibular Disorders: A Randomized Sham-controlled Trial
The aim of the study was to investigate the effectiveness of Manual Therapy Based on the Fascial Distortion Model in individuals with temporomandibular disorders compared to sham control.
- Conditions
- Temporomandibular Disorders (TMD), Manual Therapy, Fascial Distortion
- Trial name
- NCT06627855
- Testing
- Fascial Distortion Model
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Karabuk University
Temporomandibular Disorders (TMD)
Transcutaneous Electrical Nerve Stimulation for Early Pain Control in Temporomandibular Disorders
To evaluate whether adding conventional transcutaneous electrical nerve stimulation (TENS) to a standard conservative regimen (patient education, pharmacotherapy, and a home exercise programme) provides additional short- and…
- Trial name
- NCT07744893
- Testing
- Standard Conservative Therapy, Transcutaneous Electrical Nerve Stimulation (TENS)
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Balikesir University
Temporomandibular Disorder (TMD), Cervical Vertebrae
Morphometric and Morphological Analysis of Cervical Vertebrae in Disc Displacement
Temporomandibular disorders (TMDs) are multifactorial clinical conditions affecting the masticatory muscles, the temporomandibular joint (TMJ), and the surrounding structures.
- Conditions
- Temporomandibular Disorder (TMD), Cervical Vertebrae, Disc Displacement, Dentistry
- Trial name
- TMJ (NCT07429435)
- Testing
- cephalometric analysis
- Where
- Turkey (Türkiye)
- Volunteers
- 115 people
- Sponsor
- Kutahya Health Sciences University
Bruxism, Temporomandibular Disorders (TMD)
Short-Term Symptom Changes in Adults With Teeth Clenching or Grinding and Jaw Symptoms Receiving Splint, Botulinum Toxin, or Medication Plus Splint Care
This prospective observational study evaluated short-term patient-reported symptom changes in adults with bruxism-related and temporomandibular disorder symptoms who received one of three clinically selected management…
- Conditions
- Bruxism, Temporomandibular Disorders (TMD), Myofascial Pain
- Trial name
- NCT07586072
- Testing
- Occlusal splint, Botulinum Toxin Type A (Dysport®), Thiocolchicoside
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Recep Tayyip Erdogan University
Temporomandibular Disorders (TMD), Muscle Pain
Autologous Exosomes From Platelet-rich Plasma as a Modern Tool of Regenerative Dentistry
The aim of the research is the laboratory assessment of the content as well as the regenerative and anti-inflammatory potential of autologous exosomes (EXO) from platelet-rich plasma (PRP), as well as their comparison with other…
- Conditions
- Temporomandibular Disorders (TMD), Muscle Pain, TMJ Pain
- Trial name
- NCT07511959
- Testing
- Laboratory analysis of the content and biological activity of PRP, PRF, and exosomes obtained from blood samples
- Where
- Poland
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Wroclaw Medical University
Temporomandibular Disorder (TMD)
JIT: Effect of Pain on DT in TMD
Individuals with chronic temporomandibular disorder (TMD) pain are at increased risk for alcohol-related consequences compared to those without pain, and growing evidence suggests pain is a potent motivator for alcohol use in…
- Trial name
- TMD (NCT06659991)
- Testing
- alcohol condition, control condition
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Temporomandibular Disorders (TMD)
Aerobic Physical Activity and Orofacial Myofascial Pain
Orofacial myofascial pain, most commonly represented by Temporomandibular Disorders (TMD) a significant public health, affecting approximately 12% to 14% of the general population.
- Trial name
- AERODOF (NCT07526688)
- Testing
- Temporal Summation of Pain and Questionnaire
- Where
- France
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Temporomandibular Dysfunction (TMD)
Cervical Proprioception, Masticatory Pain Threshold and Craniovertebral Angle in TMD
Temporomandibular disorder (TMD) is a group of conditions involving the masticatory muscles, temporomandibular joint (TMJ), and associated structures of the head, neck, and cervical region.
- Trial name
- NCT07681570
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ankara Yildirim Beyazıt University
Temporomandibular Disorders (TMD), Temporomandibular Pain
Topical Capsaicin Versus Diclofenac for Chronic Temporomandibular Joint-Related Pain
The goal of this clinical trial is to compare the effectiveness and safety of topical capsaicin cream and topical diclofenac gel in women with chronic temporomandibular joint-related pain.
- Trial name
- NCT07598994
- Testing
- Capsaicin Topical Cream, Diclofenac 1% Topical
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Istanbul University
Temporomandibular Disorders (TMD)
Journaling Intervention for Temporomandibular Disorder (TMD) and Chronic Overlapping Pain
The goal of this clinical trial is to learn whether a 2-week gratitude journaling activity is feasible and acceptable for individuals with Temporomandibular Disorder (TMD) and chronic overlapping pain.
- Trial name
- NCT06977100
- Testing
- Gratitude, General Wellness
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Florida
Temporomandibular Disorder (TMD), Bruxism
Temporomandibular Disorders and Bruxism in Elite Basketball Referees
This study aims to determine the frequency of temporomandibular disorders (TMD) and bruxism in elite basketball referees and to compare the findings with healthy controls.
- Trial name
- NCT07662486
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Temporomandibular Disorder (TMD), Temporomandibular Joint Pain
EMVITAL + EMFACE Combination Therapy for Temporomandibular Joint (TMJ) Pain Relief
This prospective, multi-center, open-label, single-arm clinical study will evaluate the efficacy and performance of the BTL-043 and BTL-785F devices for alleviating TMJ pain.
- Conditions
- Temporomandibular Disorder (TMD), Temporomandibular Joint Pain, Facial Pain, Neck Pain
- Trial name
- NCT07661121
- Testing
- Treatment with BTL-043 and BTL-785F
- Where
- 4 sites in United States
- Volunteers
- 48 people
- Sponsor
- BTL Industries Ltd.
Temporomandibular Disorders (TMD)
The Effect of Non-Invasive Vagal Nerve Stimulation Combined With Self-Managed Therapy in Individuals With Myogenic Temporomandibular Dysfunction
The aim of our study is to determine the benefit of non-invasive Vagal Nerve Stimulation in combination with self-administered therapy on the symptoms associated with jaw joint dysfunction in individuals with jaw joint…
- Trial name
- NCT06802445
- Testing
- Self-Management Therapy, Non-Invasive Vagal Nerve Stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Toros University
TMJ Disc Disorder, Temporomandibular Joint Disc Displacement, Without Reduction
Arthroscopic Lysis and Lavage With and Without Intra-articular Injection of Hyaluronic Acid in Patients With DDwoR in TMJ
The study aims to assess the outcomes of arthroscopic lysis and lavage procedure with and without single intra-articular injection of hyaluronic acid in managing patients with anterior disc displacement without reduction.
- Conditions
- TMJ Disc Disorder, Temporomandibular Joint Disc Displacement, Without Reduction, TMD/Orofacial Pain, Temporomandibular Disorder
- Trial name
- NCT07614932
- Testing
- Arthroscopic lysis and lavage, arthroscopic lysis and lavage with intra-articular injection of hyaluronic acid
- Where
- Egypt
- Volunteers
- 52 people
- Sponsor
- Cairo University
Temporomandibular Disorders (TMD)
Ultrasound Versus Virtual Reality on Temporomandibular Disorder
The Purpose of the study is to compare between the therapeutic efficacy of ultrasound and VR in decreasing pain and improving ROM for Patients with temporomandibular joint disorder after tooth extraction surgery.
- Trial name
- NCT07575633
- Testing
- ultrasound, virtual reality
- Volunteers
- 50 people
- Sponsor
- Amany Refaat Mohamed Abdel Wahid