Clinical trials: TMJ
Temporomandibular Disorder
Safety and Efficacy of Erenumab-aooe in Patients With Temporomandibular Disorder
The purpose of this proof of concept study is to evaluate the safety and efficacy of the off-label use of Aimovig® (EREN) in reducing Temporomandibular Disorder (TMD) pain compared to placebo.
- Trial name
- NCT04884763
- Testing
- Erenumab-aooe (EREN) 140 mg s.c. administered every four weeks for a total of five treatments
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Indiana University
Laser and LED Therapy on Elderly Individuals With Temporomandibular Disorder
Effects of Laser Therapy and LED Therapy on Elderly Individuals With Temporomandibular Disorder
Temporomandibular disorder (TMD) is described as a subgroup of orofacial pain with a set of signs and symptoms that involve the temporomandibular joint, masticatory muscles, ears and neck.
- Trial name
- NCT03257748
- Testing
- Laser Therapy, LED therapy
- Where
- Brazil
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Temporomandibular Joint Syndrome
Temporomandibular Joint (TMJ) Positioning Accuracy and Efficiency Using a Dental Compass.
This study is being performed to determine if the use of the Dental Compass Articular and its software will produce therapeutic splints for TMD accurately and successfully, compare favorably with a cohort treated without the…
- Trial name
- NCT06619574
- Testing
- 3D Analysis Group, Manual Analysis Cohort
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Dr. Dean Reeves Clinic
Levonorgestrel Adverse Reaction, Temporomandibular Joint Disorders
Temporomandibular Disorder in Use of Levonorgestrel Intrauterine System
The goal of this clinical trial is to investigate the possible role of levonorgestrel intrauterine system use(LIU) in the pathogenesis of temporomandibular joint disorder (TMD).
- Conditions
- Levonorgestrel Adverse Reaction, Temporomandibular Joint Disorders, Temporomandibular Disorder
- Trial name
- NCT06500390
- Testing
- Examination of temporomandibular joint and masticator muscles
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Marmara University
Temporomandibular Disorders
Stomatognathic System Assesment, After Different Methods of Establishing the Centric Relation
Patients with complete dentures were examined after the prosthoddontic treatment with two methods of establishing a centric relation: wax rims and gothic arch tracing method.
- Trial name
- NCT03343015
- Testing
- complete dentures
- Where
- Poland
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Medical University of Silesia
Borderline Personality Disorder
Clinical Research Study to Evaluate Selegiline in the Treatment of Borderline Personality Disorder
Selegiline is superior to placebo in improving psychological and physical functioning in patients with Borderline Personality Disorder.
- Trial name
- NCT01912391
- Testing
- Selegiline
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mood and Anxiety Research, Inc
Temporomandibular Disorders (TMDs)
Psychological and Clinical Outcomes of Splint Therapy with and Without Doctor-Patient Communication in TMD Management
This study aimed to evaluate the psychological and clinical outcomes of patients undergoing splint therapy with or without enhanced doctor-patient communication in the management of temporomandibular disorders (TMDs).
- Trial name
- TMD (NCT06783530)
- Testing
- Splint Therapy with Enhanced Doctor-Patient Communication, Splint Therapy
- Where
- Egypt
- Volunteers
- 435 people
- Sponsor
- Soaad Tolba Mohammed Tolba Badawi
Ear Protective Devices, Temporomandibular Joint Disorders
The Use of Earplugs on Temporomandibular Joint
The term temporomandibular joint disorder (TMD) refers to a group of disorders affecting the temporomandibular joint and/or muscles of mastication. Typical symptoms are; joint noises, pain, and limited mouth opening.
- Conditions
- Ear Protective Devices, Temporomandibular Joint Disorders, Physical Therapy Modalities
- Trial name
- NCT05362877
- Testing
- Earplug, occlusal splint, exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Temporomandibular Joint Dysfunction Syndrome
Efficacy of Low Level LASER Therapy in Treating Temporomandibular Muscle Disorders
This study aimed to evaluate the sustainability of the efficacy of using low level laser therapy and CAD/CAM Michigan splint in improving the range of mandibular movements, muscle activity and reducing the pain.
- Trial name
- RCT (NCT05901701)
- Testing
- Low Level LASER therapy, Hard occlusal splint
- Where
- Egypt
- Volunteers
- 56 people
- Sponsor
- Ain Shams University
Counseling, Health Counseling
Lifestyle Counseling vs. Clinical Pilates in Women With Temporomandibular Disorders
The goal of this clinical trial is to evaluate the effectiveness of lifestyle counseling alone compared to lifestyle counseling combined with Clinical Pilates in women with temporomandibular disorders (TMD).
- Conditions
- Counseling, Health Counseling, Behavior Therapy
- Trial name
- LiPi-TMD (NCT07345351)
- Testing
- Life Counselling, Clinical Pilates
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- Mustafa Kemal University
Temporomandibular Joint Dysfunction Syndrome
Analysis of Clinical Data of Patients With Temporomandibular Joint Disorder
According to our previous research and clinical observation results, the motor function of the oral, maxillofacial and cervical body is closely related to the occlusal contact.
- Trial name
- NCT05780827
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Air Force Military Medical University, China
Temporomandibular Joint Disorder
Effectiveness of Vitamin B in Reducing Temporomandibular Joint Disorder Pain
The purpose of this study is to determine effectiveness of vitamin B in reducing temporomandibular joint disorder (TMD) pain. Patients will be randomised to receive the study drug or placebo.
- Trial name
- NCT02794922
- Testing
- Neurovit Forte, Corn Starch
- Where
- China
- Volunteers
- 27 people
- Sponsor
- The University of Hong Kong
TMJ Disorder
Role of Ultrasonography in Assessment of Tempromanbular Joint Disorders
Evaluation of US efficiency in assessment of the tempromandibular joint disorders in comparison with MRI as the gold standard for technique validation and evaluation of efficiency of therapeutic intra articular injection under…
- Trial name
- NCT05320770
- Testing
- US guided TMJ intra articular injection
- Volunteers
- 50 people
- Sponsor
- Sohag University
Temporomandibular Joint Dysfunction, TMD
Effects of Core Strengthening Exercises for Treating TMD
Temporomandibular disorders (TMD) are commonly managed with non-invasive interventions such as manual therapy, therapeutic exercise, relaxation techniques, and patient education.
- Conditions
- Temporomandibular Joint Dysfunction, TMD, TMJ Internal Derangement, Myofascial Pain
- Trial name
- NCT07226505
- Testing
- Experimental: Group 1: Core Strengthening, Group 2: Standard TMD PT
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Loyola University
Temporomandibular Joint Dysfunction; Myofascial Pain Syndrome; Orofacial Pain; Musculoskeletal Disorders
Reflex Therapy of Temporomandibular Dysfunctions
This study aims to evaluate the effectiveness of dry needling in patients with functional temporomandibular pain syndrome by comparing standard rehabilitation therapy alone with therapy combined with dry needling to reduce pain…
- Trial name
- NCT07321483
- Testing
- Dry needling, Standard rehabilitation
- Where
- Czechia
- Volunteers
- 100 people
- Sponsor
- Palacky University
PRP, Temporomandibular Disorder
The Platelet-Rich Plasma in the Therapy of Temporomandibular Disorders
The Platelet-Rich Plasma intramuscular injections into the masseter and temporalis muscle were performed to reduce painful temporomandibular disorder symptoms,such as myalgia, myofascial pain and myofascial pain with referrals.
- Conditions
- PRP, Temporomandibular Disorder, Myalgia, Bruxism
- Trial name
- PRP/TMD (NCT03371888)
- Testing
- Platelet-Rich Plasma intramuscular injections
- Where
- Poland
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Medical University of Silesia
Temporomandibular Joint Disorders, Temporomandibular Joint Internal Derangement
Intra-Articular PRP Versus Dexamethasone for TMJ Internal Derangement
This study looked at whether an injection into the jaw joint (temporomandibular joint, or TMJ) can help people who have pain, clicking, and difficulty opening their mouth due to a slipped joint disc.
- Conditions
- Temporomandibular Joint Disorders, Temporomandibular Joint Internal Derangement, Temporomandibular Joint Dysfunction Syndrome
- Trial name
- NCT07691684
- Testing
- Platelet-Rich Plasma (PRP), Dexamethasone with Local Anaesthetic
- Where
- Iraq
- Volunteers
- 30 people
- Sponsor
- University Of Anbar
Temporomandibular Joint Disorders
Long-term Safety and Performance of Materialise's Patient-specific TMJ System.
This is a long-term (10 years), retrospective-prospective, observational, single-arm, monocenter study of patients to be treated with the Materialise TMJ Total Arthroplasty System for TMJ replacement.
- Trial name
- NCT06951178
- Testing
- TMJ Total Arthroplasty System (TMJ System)
- Where
- Denmark
- Volunteers
- 30 people
- Sponsor
- Materialise
Temporomandibular Joint Dysfunction Syndrome
The Application of Radio Frequency Waves
The aim of the study was to evaluate the influence of radio waves on the functioning of masseter muscles in the course of painful functional disorders of the organ, and thus the usefulness of these procedures in the treatment…
- Trial name
- NCT03773640
- Testing
- Radio frequency currents, Sonophoresis
- Where
- Poland
- Volunteers
- 40 people
- Sponsor
- Jagiellonian University
Temporomandibular Disorders (TMDs)
Quality of Life and Sleep in Patients With Temporomandibular Disorders
The aim of this study is to evaluate and compare the effects of two physiotherapeutic intervention programs on the quality of life in patients with Temporomandibular Disorders (TMD).
- Trial name
- NCT07056725
- Testing
- Manual Therapy and Therapeutic Exercises Programs
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- University of Jaén