Clinical trials: TMJ Disorders
Temporomandibular Disorders (TMD), Disc Displacement
Differential Impact of TMJ Disc Displacement and Muscle Disorders on Pain, Function, and Quality of Life in TMD Patients
This study aims to explore the relationship between the position of the temporomandibular joint (TMJ) disc and key clinical outcomes in patients with temporomandibular disorders (TMD).
- Conditions
- Temporomandibular Disorders (TMD), Disc Displacement, Functional Impairment
- Trial name
- DPTMD (NCT06758479)
- Where
- India
- Volunteers
- 100 people
- Sponsor
- King Khalid University
Temporomandibular Joint Disorders, TMD
Efficacy and Safety of HA35 Gel Nighttime Occlusive Application for TMD Pain
This is a prospective, single-arm, open-label, pilot clinical study to evaluate the efficacy and safety of nighttime occlusive application of 10% high-concentration 35 kDa hyaluronan (HA35) gel in subjects with temporomandibular…
- Conditions
- Temporomandibular Joint Disorders, TMD, Temporomandibular Joint Pain, Jaw Muscle Over-Tension
- Trial name
- HA35-TMJ (NCT07584642)
- Testing
- 10% High-Concentration 35 kDa Hyaluronan (HA35) Topical Gel
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Nakhia Impex LLC
Pain, Head, Pain Syndrome
Botulinum Toxin Versus Placebo Injections to Temporalis and Masseter Muscles
This study aims to determine whether the injection of botulinum toxin A or placebo (unpreserved 0.9% sodium chloride) into the masseter and temporalis muscles provides pain relief and improved jaw function in those who suffer…
- Conditions
- Pain, Head, Pain Syndrome, Temporomandibular Disorder, Myofascial Pain Syndrome
- Trial name
- NCT03223298
- Testing
- Botulinum toxin type A, 0.9% Sodium Chloride Injection
- Where
- 2 sites in United States
- Volunteers
- 75 people
- Sponsor
- Weill Medical College of Cornell University
TMD, TMD/Orofacial Pain
Treatment Outcomes in Patients With Muscular Temporo-mandibular Joint Disorders
The aim of the present study was to assess the treatment outcomes in patients affected by M-TMDs in terms of pain scores assessed with pressure pain threshold (PPT).
- Trial name
- NCT06339736
- Testing
- Questionnaires administered to all study participants
- Where
- Italy
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Pisa
Chronic TMD Pain, Temporomandibular Disorder
R01_Pilot Jaw Muscle Phenotypes
The proposed study will assess the effect of local heat therapy on jaw pain and jaw fatigue secondary to a teeth clenching task in chronic TMD pain cases.
- Trial name
- NCT07153107
- Testing
- Local Heat Therapy
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Minnesota
Temporomandibular Joint Internal Derangement (ADWR)
Evaluation of Intravenous Sodium Valproate on Interleukin-6 Levels in Patients With TMJ Disc Displacement
This study aims to evaluate if adding the medication Sodium Valproate to a standard jaw procedure (arthrocentesis) can help reduce inflammation and improve healing in patients with certain jaw joint problems.
- Trial name
- NCT07487675
- Testing
- sodium valproate, TMJ Arthrocentesis
- Where
- Egypt
- Volunteers
- 10 people
- Sponsor
- Tanta University
Temporomandibular Disorder (TMD), Chronic Pain
Patient Education, Self-management and Physiotherapy for Chronic Temporomandibular Disorders
The goal of this clinical trial is to understand whether a simple education and self-management program with home exercises can reduce pain and improve daily function in adults with long-lasting jaw pain caused by…
- Trial name
- NCT07423234
- Testing
- Patient education and self-management, Usual treatment (multimodal)
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Temporomandibular Disorders (TMDs), Myofascial Pain - Dysfunction Syndrome of TMJ
Comparison of Conventional,3D Printed and Novel Hybrid Stabilization Splints in the Management of Temporomandibular Joint Disorders
Occlusal splint therapy is a well-established conservative approach for the management of temporomandibular disorders (TMDs); however, variability in clinical outcomes suggests that no single splint design is universally optimal.
- Conditions
- Temporomandibular Disorders (TMDs), Myofascial Pain - Dysfunction Syndrome of TMJ, Myofascial Pain Dysfunction Syndrome, Temporomandibular Joint, Anterior Disc Displacement
- Trial name
- NCT07760428
- Testing
- Conventional Stabilization Splints, 3d printed Stabilization splint, Novel hybrid stabilization splint
- Where
- India
- Volunteers
- 36 people
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Recurrent Dislocation of Temporomandibular Joint (Disorder)
Evaluation of Using Patient Specific Zirconium Dioxide Implant Versus Patient Specific Titanium Implant in Treatment of Chronic Condylar Dislocation
Alternate hypothesis that treatment of Tempromandibular joint dislocation with Zirconium Dioxide eminoplasty will be more efficient than using titanium onlays in terms of decreasing maximum inter incisal distance and providing…
- Trial name
- NCT05377593
- Testing
- eminoplasty with patient specific Zirconium dioxide onlay implant
- Where
- Egypt
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Cairo University
Temporomandibular Disorders (TMD), Sleep
ASSOCIATION BETWEEN TEMPOROMANDIBULAR DISORDERS AND SLEEP DISORDERS
ASSOCIATION BETWEEN TEMPOROMANDIBULAR DISORDERS AND SLEEP DISORDERS
- Trial name
- Gnathology TMD (NCT06975709)
- Testing
- Questionnaire and Physical Exam
- Where
- 2 sites in Italy
- Volunteers
- 100 people
- Sponsor
- IRCCS San Raffaele
Temporomandibular Joint Disorders
Comparing Two-Needle vs. Surgery-Guided Arthrocentesis for TMJ Disorders
The goal of this clinical trial is to compare two methods of arthrocentesis in treating temporomandibular joint (TMJ) disorders.
- Trial name
- NCT06055855
- Testing
- Traditional Two-Needle Arthrocentesis, Surgery-Guided Arthrocentesis
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Marmara University
Temporomandibular Disorder
Osteopathic Manipulative Treatment in Individuals With Temporomandibular Disorder Who Make Use of Occlusal Splints
This study aim to contribute with the investigation of the therapeutic effect of osteopathic manipulative treatment in pain intensity and Quality of Life in individuals diagnosed with temporomandibular disorder who make use of…
- Trial name
- NCT02991326
- Testing
- Osteopathic Manipulative Treatment
- Where
- Brazil
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Universidade Federal Fluminense
PARKINSON DISEASE (Disorder), Rigidity
Spinal Mobility, Rigidity, and Kinesiophobia in PD and TMD
Axial rigidity and loss of spinal mobility commonly observed in Parkinson's disease (PD) lead to postural deformities and substantial reductions in trunk flexibility.
- Conditions
- PARKINSON DISEASE (Disorder), Rigidity, Temporomandibular Disorders (TMDs), Mobility
- Trial name
- NCT07850674
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mustafa Kemal University
COVID-19, Temporomandibular Disorder
Temporomandibular Joint and COVID-19
There is evidence that CV-19 is associated with joint symptoms, but there are no specific data on the temporomandibular joint (TMJ). It is also known that the systemic health status can impact the immune system.
- Conditions
- COVID-19, Temporomandibular Disorder, ASA Triad
- Trial name
- NCT05077189
- Testing
- Diagnostic Criteria for Temporomandibular Disorders (DC/TMD) scale
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University Training and Research Hospital
Tinnitus
Physiotherapeutic Approach to Tinnitus
Intervention experiments in the physiotherapeutic field targeted diagnostics and therapy of tinnitus. The goal is to find various groups of tinnitus patients and an ideal therapeutic approach between physical therapy means…
- Trial name
- NCT05667168
- Testing
- physiotherapy approach
- Where
- Czechia
- Volunteers
- 400 people
- Sponsor
- Charles University, Czech Republic
Temporomandibular Joint Disorders
Exploratory Study To Assess the Efficacy and Safety of a Triple Combination for Acute Pain Treatment in Patients With Temporomandibular Joint Disorders (TMJD).
The objetive of this study is to explore the efficacy and safety of a triple combination of ibuprofen, magnesium and ascorbic acid for acute pain treatment in TMJD patients
- Trial name
- NCT02602483
- Testing
- Ibuprofen, Magnesium, Ascorbic Acid
- Where
- 4 sites in Spain
- Volunteers
- 96 people
- Sponsor
- Spherium Biomed
Bruxism, Posture
Determining the Relationship Between Posture, Muscle Stiffness, Pain, and Jaw Functionality in Individuals With Bruxism
Bruxism is a repetitive jaw-muscle activity characterized by teeth clenching and/or grinding, often associated with temporomandibular joint dysfunction, pain, and impaired jaw function.
- Conditions
- Bruxism, Posture, Sleep Quality, Pain Assessment
- Trial name
- Bruxism (NCT07560670)
- Testing
- Bruxism Assessment Form, Clinical Examination, Patient Evaluation Form
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Istanbul Kent University
Temporomandibular Disorders (TMD)
Physiotherapy Investigation in Patient With Temporomandibular Joint Dysfunction
Knowing the associated factors for people suffering from TMD may help to develop preventive, therapeutic and health strategies. The aim of this study was to present the assessments of audiovestibular symptoms in people with TMD.
- Trial name
- NCT06722833
- Volunteers
- 70 people
- Sponsor
- Uskudar University
Temporomandibular Disorders
Evaluation of Influence of Two Treatment Protocols on Mandibular Movements and Condyle-fossa Relation
The edentulism and use of inadequate dentures, unstable and with teeth worn because long period of usage can lead to an disharmony of the stomatognathic system due to gradual loss of occlusion vertical dimension resulting in…
- Trial name
- NCT02015585
- Testing
- interocclusal appliance, Relining of the complete dentures, Complete denture rehabilitation
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Federal University of Pelotas
Myofascial Pain - Dysfunction Syndrome of TMJ
Dry Needling Vs Transcutaneous Electrical Nerve Stimulation in Management of Myofascial Pain Dysfunction Syndrome
Myofascial pain dysfunction syndrome (MPDS) is the most common form of temporomandibular disorders. Because of the multifactorial nature of the problem, its management is still not definite.
- Trial name
- NCT06583915
- Testing
- TENS, Dry Needle
- Volunteers
- 26 people
- Sponsor
- Cairo University