Clinical trials: TMJ Pain
Temporomandibular Disorder
Evaluation of the Efficacy of Different Drugs in the Treatment of the Pain in Patients With Temporomandibular Disorder
The most important step in the treatment of TMJ (temporomandibular joint) disease in clinical dentistry is diagnosis and planning.
- Trial name
- NCT05529290
- Testing
- Dexketoprofen Trometamol + Thiocolchicoside, Dexketoprofen Trometamol + Paracetamol, Dexketoprofen Trometamol (25mg)
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Yuzuncu Yil University
Bruxism, TMJ Pain
Effect of Manual Therapy on Jaw Movement and Function in Patients With Bruxism
Hypothesis 1. There will be no significant statistical effect of Trigger Point Pressure release and Deep striking massage on pain level in patients with bruxism. 2.
- Trial name
- NCT03753529
- Testing
- Deep friction massage, Pressure release, control group
- Volunteers
- 120 people
- Sponsor
- Cairo University
Temporomandibular Disorder, Central Sensitisation
Effects of Aerobic Exercise on Pain in Patients With Myogenous Temporomandibular Disorders and Suspicion of Central Sensitization
Temporomandibular disorders are common in the general population, the myogenic subtype being the most frequent. Central sensitization seems to be present in this pathology, with a decreased pain pressure threshold observed in…
- Conditions
- Temporomandibular Disorder, Central Sensitisation, Myofascial Pain Syndrome, Endurance Training
- Trial name
- NCT05540366
- Testing
- Physical therapy combined with aerobic exercise, Physical Therapy
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Universitat Internacional de Catalunya
Women, Osteoporosis
Temporomandibular Disorders and Osteoporosis
Increased life expectancy has attracted research attention, interested in provide a quality and healthy aging. According to the latest census conducted in 2010 by IBGE, Brazilian population consists of 97,342,162 women, whom…
- Conditions
- Women, Osteoporosis, Osteopenia, Temporomandibular Disorder
- Trial name
- TMDOST (NCT01029210)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Temporomandibular Joint Dysfunction, TMD
Effects of Core Strengthening Exercises for Treating TMD
Temporomandibular disorders (TMD) are commonly managed with non-invasive interventions such as manual therapy, therapeutic exercise, relaxation techniques, and patient education.
- Conditions
- Temporomandibular Joint Dysfunction, TMD, TMJ Internal Derangement, Myofascial Pain
- Trial name
- NCT07226505
- Testing
- Experimental: Group 1: Core Strengthening, Group 2: Standard TMD PT
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Loyola University
Chronic Migraine, Headache, Temporomandibular Joint Dysfunction
The Effect of Accompanying Temporomandibular Joint Dysfunction in Patients With Chronic Migraine
The aim of this clinical study to evaluate the effect of temporomandibular joint dysfunction accompanying patients with chronic migraine on pain, quality of life, sleep and functionality.
- Conditions
- Chronic Migraine, Headache, Temporomandibular Joint Dysfunction, Chronic Pain, Quality of Life
- Trial name
- NCT05381129
- Testing
- Detection of Pain, Quality of Life, Sleep and Functioning, Temporomandibular joint dysfunction
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- Istanbul University - Cerrahpasa
Myalgia, Apnea, Obstructive Sleep
Temporomandibular Disorder (TMD) Pain in Response to Jaw Advancement in People With TMD and Obstructive Sleep Apnea
The purpose of this study is to characterize the course of temporomandibular disorder (TMD) pain in adults with TMD and obstructive sleep apnea (OSA), all of whom are being treated with mandibular advancement splint (MAS)…
- Trial name
- NCT02685202
- Testing
- Mandibular advancement splint
- Volunteers
- 9 people
- Sponsor
- University of North Carolina, Chapel Hill
Temporomandibular Disorder
The Effect Of Core Stability Training In Temporomandibular Disorders
This study is to investigate the effect of Core stability training on pain, function, quality of life, sleep quality, body posture, foot posture, oral habits and kinesiophobia in individuals with temporomandibular disorder.
- Trial name
- NCT04755621
- Testing
- Core stability training, Rocabado Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
Temporomandibular Joint Disease
Effect of Emg-Biofeedback and Multimodal Exercise on Temporomandibular Joint Dysfunction
Temporomandibular joint dysfunction (TMD) is a multifactorial musculoskeletal disorder affecting the masticatory muscles, temporomandibular joint, and related structures, characterized by pain and functional limitations.
- Trial name
- NCT07577687
- Testing
- Multimodal physiotherapy program, EMG-Biofeedback
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Yuzuncu Yil University
Temporomandibular Disorders
Erenumab-aooe for Temporomandibular Disorders Management: TMD Cgrp Antibody RElief (TMD CARE)
Evaluate erenumab- aooe efficacy as a therapeutic approach, for the management of painful chronic temporomandibular disorders (TMD).
- Trial name
- TMD CARE (NCT05162027)
- Testing
- Erenumab-Aooe 70 MG in 1 mL Prefilled Syringe
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of Maryland, Baltimore
Temporomandibular Disorders
Stretching Exercises and Temporomandibular Disorders
To compare the efficacy of global postural reeducation (GPR) with static stretching exercises (SS) in the treatment of women with temporomandibular disorders (TMD).
- Trial name
- Stretching (NCT00993577)
- Testing
- Stretching exercises, Exercises
- Where
- 2 sites in Brazil
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Temporomandibular Joint Pain
TMD Pulsed Radiofrequency
PRF of the masticatory muscles (masseter, temporalis, medial and lateral pterygoid muscle) can improve pain intensity and functional recovery of the jaw in patients with extra-articular TMD.
- Trial name
- NCT03848169
- Testing
- Radiofrequency
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Temporomandibular Disorder, Neck Pain
How is Aerobic Exercise Compared to Localized Pain Relief Exercises in Patients With Jaw Pain and Neck Pain?
Musculoskeletal (MSK) disorders are some of the most burdensome health issues in the world and the leading causes of years living with a disability.
- Trial name
- NCT05232604
- Testing
- Aerobic exercise, Neck motor control exercise
- Where
- Germany
- Volunteers
- 42 people
- Sponsor
- Hochschule Osnabruck
Whiplash, Temporomandibular Joint Pain
Evaluate the Effect of Dry Needling on the Temporomandibular Joint in Subjects Who Have Suffered a Whiplash as a Result of a Traffic Accident
The transportation industry is growing rapidly and the most popular mode is overland by road. Traffic accidents are the most direct and serious risk to the lives of Western people.
- Conditions
- Whiplash, Temporomandibular Joint Pain, Dry Needling Technique
- Trial name
- NCT06023264
- Testing
- Dry needling
- Where
- 2 sites in Spain
- Volunteers
- 50 people
- Sponsor
- Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz
Dysphagia, Oral Phase, Temporomandibular Disorders
Efficacy of the Myofunctional Therapy on Oral Dysphagia
The aim of the study is to analyze the effects of orofacial myofunctional therapy (OMT) on oral dysphagia (OD) in patients with temporomandibular disorders (TMD).
- Trial name
- NCT04636606
- Testing
- Home Exercise, Manual Therapy Combined with Home Exercise, Orofacial Myofunctional Therapy combined with Manual Therapy and Home Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Hasan Kalyoncu University
Pain
Assessment of Peripheral GABA Receptors for Local Pain Relief
The effect of peripheral GABAA receptor activation on pain and sensitivity in healthy human subjects has never been investigated.
- Trial name
- NCT02928328
- Testing
- GABA oral solution, Intramuscular GABA, Pain modulation
- Where
- Denmark
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Aalborg University
Temporomandibular Joint Disorder
Optimizing Resilience In Orofacial Pain and Nociception
The purpose of this study is to examine the effects of a hope-based intervention on clinical and experimental pain in individuals with temporomandibular disorder (TMD).
- Trial name
- ORION (NCT02164630)
- Testing
- Hope Therapy, Pain Education
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University of Florida
Temporomandibular Disorders
Peripheral TMD Pain Mechanisms and the Effect by Botulinum Toxin A
The goal of this clinical trial is to investigate the effect of botulinum toxin on neurons' plasticity in the masseter muscle in humans with and without painful myogenous temporomandibular disorders (TMDM).
- Trial name
- NCT05720065
- Testing
- Botulinum toxin type A, Isotonic saline 0,9%
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Karolinska Institutet
Other Disorders of Muscle in Diseases Classified Elsewhere
Myorelaxant Effect of Bee Venom(BV) Topical Skin Application in Patients With RDC/TMD Ia and Ib
Topical application of BV ointment in patients with Research Diagnostic Criteria/Temporomandibular Disorder 1a and 1b (RDC/TMD) in experimental group, compared to placebo (vaseline) in control group.Application was repeated 3…
- Trial name
- BV/TMD (NCT02101632)
- Testing
- Bee Venom Ointment, Vaseline Ointment
- Where
- Poland
- Volunteers
- 79 people
- Sponsor
- Medical University of Silesia
Temporomandibular Disorders (TMD)
The Effect of Non-Invasive Vagal Nerve Stimulation Combined With Self-Managed Therapy in Individuals With Myogenic Temporomandibular Dysfunction
The aim of our study is to determine the benefit of non-invasive Vagal Nerve Stimulation in combination with self-administered therapy on the symptoms associated with jaw joint dysfunction in individuals with jaw joint…
- Trial name
- NCT06802445
- Testing
- Self-Management Therapy, Non-Invasive Vagal Nerve Stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Toros University