Clinical trials: Tailored Condition
Autoimmune Hepatitis
Tacrolimus Versus Mycophenolate for Autoimmune Hepatitis Patients With Incomplete Response on First Line Therapy
Rationale: The combination of azathioprine and prednisone is the first-line treatment for autoimmune hepatitis (AIH), a chronic inflammatory disease of the liver.
- Trial name
- TAILOR (NCT05221411)
- Testing
- Mycophenolate Mofetil, Tacrolimus
- Where
- 6 sites in Netherlands
- Volunteers
- 86 people
- Sponsor
- Leiden University Medical Center
Ischemic Stroke, Upper Extremity Hemiparesis
Patient-tailored Transcranial Direct Current Stimulation to Improve Stroke Rehabilitation
In a double-blinded sham-controlled study the effect of patient-tailored transcranial direct current stimulation during rehabilitation training will be examined.
- Trial name
- PRACTISE (NCT05355831)
- Testing
- Active Transcranial Direct Current Stimulation
- Where
- 3 sites in Denmark
- Volunteers
- 22 people
- Sponsor
- Christina Kruuse
Cardiovascular Disease, Coronary Heart Disease
Heart to Health: A Combined Lifestyle and Medication Intervention to Reduce Cardiovascular Disease (CVD) Risk
Cardiovascular disease (CVD), including heart disease and stroke, is the leading cause of death in the US. Every year, more than one million Americans have a heart attack, and nearly 800,000 have a stroke.
- Trial name
- NCT01245686
- Testing
- Lifestyle and medication intervention
- Where
- 5 sites in United States
- Volunteers
- 489 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Ventral Hernia, Surgery
STRONG for Surgery & Strong for Life - Intensive Prehabilitation for Risk Reduction in Ventral Hernia Repair
The five risky lifestyles Smoking, Nutrition (obesity and malnutrition), risky Alcohol intake, and Physical inactivity (SNAP) are common in surgical patients and associated with worse postoperative outcomes.
- Conditions
- Ventral Hernia, Surgery, Risk Reduction, Lifestyle
- Trial name
- STRONG-Hernia (NCT06611462)
- Testing
- Prehabilitation (the STRONG programme)
- Where
- 3 sites in Denmark
- Volunteers
- 400 people
- Sponsor
- Bispebjerg Hospital
B-Cell Non-Hodgkin Lymphoma
Tailored Prednisone Reduction in Preventing Hyperglycemia in Participants With B-Cell Non-Hodgkin Lymphoma Receiving Combination Chemotherapy Treatment
This phase II trial studies how well tailored prednisone reduction works in preventing hyperglycemia in participants with B-cell non-Hodgkin lymphoma receiving combination chemotherapy treatment.
- Trial name
- NCT03505762
- Testing
- Cyclophosphamide, Doxorubicin Hydrochloride, Laboratory Biomarker Analysis
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Wake Forest University Health Sciences
Myeloproliferative Neoplasms (MPN)
Exercise Training in Patients With Myeloproliferative Neoplasms
The investigators will investigate the response of an individualized exercise training program on quality of life, cardiorespiratory fitness and disease-specific markers in patients with myeloproliferative neoplasms (MPN).
- Trial name
- MPN-Exercise (NCT07384039)
- Testing
- Exercise Training
- Where
- 2 sites in Germany
- Volunteers
- 80 people
- Sponsor
- Hannover Medical School
Depression, Anxiety, Cancer
Evaluating a Tailored Cognitive Behavioral Therapy for Adolescent and Young Adult Cancer Patients
This project's overall goal is to test the feasibility, acceptability and efficacy of two coach-assisted, computer-based, cognitive- behavioral therapy (C-CBT) interventions in treating depression and anxiety in adolescent and…
- Trial name
- NCT04773197
- Testing
- Beating the Blues (BtB), Entertain Me Well (EMW), Coaching
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- University of Michigan Rogel Cancer Center
End Stage Renal Disease Requiring Hemodialysis
Can Dietitians Reduce Interdialytic Weight Gain in at Risk Hemodialysis Patients Through Tailored Education on Dietary Sodium and Fluid Intake?
The purpose of this project is to understand if more frequent education of dialysis patients (patients with kidney failure who get their blood cleaned and fluid removed by a machine instead of their kidneys) on reducing sodium…
- Trial name
- NCT02130089
- Testing
- Intensive Tailored Education
- Where
- New Zealand
- Volunteers
- 50 people
- Sponsor
- Academy of Nutrition and Dietetics
HIV Infections
Development of a Tailored HIV Prevention Intervention for Young Men
This study uses an interactive design and development process to develop tailored messages that align YMSM's relationship experiences and desires with HIV prevention strategies.
- Trial name
- myDEx (NCT02842060)
- Testing
- myDEx, NTHP
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Overweight and Obesity, Physical Activity
Healthy Mom Zone: A Gestational Weight Gain Management Intervention
The purpose is to establish feasibility of delivering an individually-tailored, behavioral intervention to manage gestational weight gain [GWG] that adapts to the unique needs and challenges of overweight/obese pregnant women…
- Conditions
- Overweight and Obesity, Physical Activity, Weight Change, Body, Eating Behavior
- Trial name
- HMZ (NCT03945266)
- Testing
- Intervention group, Control group
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Penn State University
Prostate Cancer
Personal Patient Profile Prostate (P4) Randomized, Multisite Trial
The purpose of this study is to determine whether or not participation in an experimental program called the "P4 program" is useful to men who are faced with choices about treatment for their early stage prostate cancer.
- Trial name
- P4 (NCT00692653)
- Testing
- P4
- Where
- 6 sites in United States
- Volunteers
- 498 people
- Sponsor
- Dana-Farber Cancer Institute
Cancer, Metastatic Breast Cancer
Adaptation of a Values Assessment Tool
The primary purpose of this study is to evaluate the effect of values assessment tool on patient and caregiver perception of decisional conflict, and communication with their oncology clinician.
- Trial name
- NCT07068477
- Testing
- Values Assessment Tool
- Where
- United States
- Volunteers
- 67 people
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
HFpEF - Heart Failure With Preserved Ejection Fraction, Diabetic Cardiomyopathies
Tailored Exercise Training Study Among Adults With HFpEF
Heart failure with preserved ejection fraction (HFpEF) is associated with a high morbidity and mortality burden. There are limited pharmacological options available for the treatment of HFpEF.
- Trial name
- TEXPEF (NCT07223242)
- Testing
- Moderate-intensity continuous training (MCT), Resistance training, Weight loss
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Texas Southwestern Medical Center
Diabetes
Culturally Tailored Behavioral Diabetes Care Intervention for Korean Americans
The purpose of this study is to assess the feasibility and efficacy of a culturally-tailored, comprehensive behavioral intervention program specially designed for linguistically challenged ethnic minority immigrant populations…
- Trial name
- NCT00505960
- Testing
- Diabetes Care for Korean Americans
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Johns Hopkins University
Hypertension (HTN)
Effects of a Health Literacy-tailored Self-management Intervention on People With Hypertension
This project aims to investigate the effects of a health literacy-tailored self-management intervention among people with hypertension and low health literacy.
- Trial name
- NCT07369479
- Testing
- health literacy-tailored self-management intervention
- Volunteers
- 170 people
- Sponsor
- Chinese University of Hong Kong
Alcohol Drinking, Binge Drinking
Alerta Alcohol. Web-based Computer-tailored Intervention for Binge-drinking Prevention in Spanish Adolescents
This study consists in the the design, implementation, and evaluation of the first web-based computer tailored intervention program aimed at the prevention of binge drinking in Spanish adolescents (Alerta Alcohol).
- Conditions
- Alcohol Drinking, Binge Drinking, Adolescent Behavior
- Trial name
- NCT03288896
- Testing
- Alerta Alcohol
- Where
- Spain
- Volunteers
- 1,230 people, healthy volunteers welcome
- Sponsor
- University of Seville
Pre Diabetes, Type2 Diabetes
Diabetes Prevention AI: Enhancing Prevention Strategies Using Personalized Nutrition and Fitness Coaching for the Next Generation
This study is testing an artificial intelligence (AI) chatbot designed to help adults at risk for type 2 diabetes adopt healthier lifestyles.
- Trial name
- NCT07824154
- Testing
- AI-Powered Diabetes Prevention Chatbot
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Emory University
Heart Failure
Mutton Heart Failure Food is Medicine Pilot
Study subjects with heart failure will receive either pre-prepared, home-delivered DASH/SRD-compliant meals incorporating local Navajo traditional foods or usual care for 30 days (14 meals weekly).
- Trial name
- Mutton-HF (NCT06675331)
- Testing
- Medically Tailored Meal Program with Traditional Navajo Foods
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Pennsylvania
Diabetes, Gestational, Gestational Weight Gain
Meals for Moms: Medically-Tailored Meals for Women Who Had Gestational Diabetes
The purpose of this research study is to test whether delivery of medically tailored meals (meals designed specifically to be healthy) can be used to help reduce high blood sugar after delivery of a baby.
- Conditions
- Diabetes, Gestational, Gestational Weight Gain, Postpartum Weight Retention
- Trial name
- NCT04866823
- Testing
- Medically Tailored Meals
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Wake Forest University Health Sciences
ADHD
Classroom Behavior Support (CBS) Project
The goal of the study is to conduct a randomized clinical trial to evaluate the impact of the Classroom Behavior Support Program (CBS; a multi-component, individually-tailored teacher consultation program) on teachers' classroom…
- Trial name
- CBS (NCT05137327)
- Testing
- Classroom Behavior Support (CBS) Condition, Standard Problem Solving Consultation
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Ohio University