Clinical trials: Tailored Condition
Diabetes Mellitus, Type 2
Online Program Assisting Lifestyle Changes (Asterix 1.0 & Obelix 2.0)
The purpose of this study is to help Internet users to adopt and maintain a healthy lifestyle, it is imperative to increase self-management competencies to improve healthy eating and regular physical activity.
- Trial name
- OPAL (NCT00986375)
- Testing
- Intervention Group (IG), Active Control Group (ACG)
- Where
- Germany
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Freie Universität Berlin
HIV/AIDS, Depression
Tailored Response to Psychiatric Comorbidity to Improve HIV Care Engagement in the United States
This pilot randomized clinical trial will randomize 60 participants 1:1 to either enhanced usual care or to adapted Common Elements Treatment Approach (CETA), a counseling intervention for HIV care engagement plus depression…
- Conditions
- HIV/AIDS, Depression, Anxiety, Post-traumatic Stress Disorder
- Trial name
- TRACE (NCT04163341)
- Testing
- Adapted Common Elements Treatment Approach
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Michael J Mugavero, MD
Head and Neck Cancer, Alcohol Use, Unspecified
Alcohol Cessation Among Head and Neck Cancer Survivors
Head-and-neck cancers (HNC) account for 4 percent of cancer diagnoses in the United States and for more than 66,000 annual cancer diagnoses.
- Trial name
- NCT05570851
- Testing
- Alcohol Cessation Text Messages, Usual Care
- Where
- United States
- Volunteers
- 126 people
- Sponsor
- Northwell Health
Pompe-Disease
ERT in Pompe Disease: Elucidation of Molecular Structures Contributing to Enzyme Uptake and Immunoreactivity
In the first part of this study, the aim is to characterize the molecular structure of wildtype GAA and, in particular, of mutated GAA variants with and without HSAT, in order to learn how mutation impairs uptake of GAA into the…
- Trial name
- NCT05448131
- Where
- Germany
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Centre for Analytical Biochemistry and Biomedical Mass Spectrometry
Cervical Cancer
BrUOG 355: Nivolumab to Tailored Radiation Therapy With Concomitant Cisplatin in the Treatment of Patients With Cervical Cancer
This research study is a Phase II clinical trial. Phase II clinical trials test the safety and effectiveness of the investigational drug in combination with radiation to learn whether the drug(s) works in treating a specific…
- Trial name
- NCT03527264
- Testing
- Nivolumab induction, Cisplatin, Radiation
- Where
- 2 sites in United States
- Volunteers
- 4 people
- Sponsor
- Brown University
Type 2 Diabetes
Resilience-Based Diabetes Self-Management Education (RB-DSME) for African Americans
African Americans are twice as likely to have type 2 diabetes as non-Hispanic Whites and are less likely to engage in effective diabetes self-management.
- Trial name
- TXSTRIDE (NCT04282395)
- Testing
- Resilience-Based Diabetes Self-Management Education, Standard Diabetes Self-Management Education
- Where
- United States
- Volunteers
- 284 people
- Sponsor
- University of Texas at Austin
Atrial Fibrillation
Reappraisal of Atrial Fibrillation: Interaction Between HyperCoagulability, Electrical Remodeling, and Vascular Destabilisation in the Progression of Atrial Fibrillation
The purpose of this study is to study clinical factors and (blood) biomarkers related to progression of Atrial Fibrillation (AF) in patients diagnosed with self-terminating AF with special reference to hypercoagulability.
- Trial name
- RACE V (NCT02726698)
- Where
- 9 sites in Netherlands
- Volunteers
- 750 people
- Sponsor
- University Medical Center Groningen
Persistent Depressive Disorder
Feasibility and Effectiveness of a Personalized Inpatient Program for Persistent Depressive Disorder
The major objective of this study is to evaluate a new conceptualized personalized concept of Cognitive Behavioral Analysis System of Psychotherapy (CBASPersonalized) in the treatment of patients with persistent depressive…
- Trial name
- PePsy (NCT03616665)
- Testing
- CBASPersonalized
- Where
- 2 sites in Germany
- Volunteers
- 100 people
- Sponsor
- Philipps University Marburg
Anxiety, Autism Spectrum Disorder
Adaptation and Feasibility of the Community-Based Anxiety Program Tailored for Autism (CAPTA)
Anxiety is very common in autistic youth. Recently, an intervention has been created by the investigators to target these symptoms in autistic youth in a community setting.
- Conditions
- Anxiety, Autism Spectrum Disorder, Separation Anxiety, Generalized Anxiety Disorder
- Trial name
- NCT06046170
- Testing
- Cognitive Behavioral Therapy, Treatment as Usual
- Where
- 3 sites in United States
- Volunteers
- 32 people
- Sponsor
- Baylor College of Medicine
Asthma
The Importance of Tailored Education And Device Handling for Asthmatic Patients
Significant advancements have been made in asthma medication over the past decades. Highly effective treatments are available for patients; however, both adherence and proper device usage remain below the desired levels, based on…
- Trial name
- TEACH (NCT06840522)
- Where
- 6 sites in Hungary
- Volunteers
- 250 people
- Sponsor
- Chiesi Hungary Ltd.
Breast Cancer, Obesity
Weight Loss Counseling for African American Women Who Are Breast Cancer Survivors
RATIONALE: A culturally sensitive weight loss program for obese African American breast cancer survivors may be more effective than a standard weight loss program in helping women lose weight.
- Conditions
- Breast Cancer, Obesity, Weight Changes
- Trial name
- NCT00872677
- Testing
- Diet, Spiritual counseling
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Barbara Ann Karmanos Cancer Institute
Obstructive Sleep Apnea
Lifestyle and Physical Activity as Part Of Obstructive Sleep Apnea Treatment
The goal of this clinical trial is to investigate the effects of an individually tailored lifestyle intervention on symptoms and severity of obstructive sleep apnea (OSA), physical activity (PA) levels and sedentary behavior…
- Trial name
- ELO (NCT06382883)
- Testing
- Individually tailored lifestyle and physical activity intervention, Individually tailored lifestyle and physical activity intervention combined with enhanced behavioral support -intervention (EBS)
- Where
- Finland
- Volunteers
- 300 people
- Sponsor
- Filha ry
Prostate Cancer
Efficacy of a Couple-Focused mHealth Symptom Self-management Program
In this study, the investigators propose to test the efficacy of a couple-focused, web-based tailored prostate cancer symptom management program, Prostate Cancer Education and Resources for Couples (PERC) in a randomized clinical…
- Trial name
- NCT03489057
- Testing
- Prostate Cancer Education and Resources for Couples (PERC), usual care plus NCI website
- Where
- United States
- Volunteers
- 560 people, healthy volunteers welcome
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Headaches
Tailored Internet Information Supply for Patients - Part 2
Medical expert systems in combination with portal searching meta-search engines are exploited to provide reliable patient-tailored information.
- Trial name
- NCT00921453
- Where
- Germany
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Health & Life Sciences University, Tryol
Sexually Transmitted Infection, HIV
Repeat Sexually Transmitted Infection (STI) Patients: Tailored Socio-Contextual Intervention to Reduce HIV Risk
People who present repeatedly at Sexually Transmitted Infection (STI) clinics represent a key population for HIV prevention intervention research.
- Trial name
- NCT01510262
- Testing
- Tailored Socio-Contextual Intervention, Standard of Care
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- University of Wisconsin, Milwaukee
Ventral Hernia, Surgery
STRONG for Surgery & Strong for Life - Intensive Prehabilitation for Risk Reduction in Ventral Hernia Repair
The five risky lifestyles Smoking, Nutrition (obesity and malnutrition), risky Alcohol intake, and Physical inactivity (SNAP) are common in surgical patients and associated with worse postoperative outcomes.
- Conditions
- Ventral Hernia, Surgery, Risk Reduction, Lifestyle
- Trial name
- STRONG-Hernia (NCT06611462)
- Testing
- Prehabilitation (the STRONG programme)
- Where
- 3 sites in Denmark
- Volunteers
- 400 people
- Sponsor
- Bispebjerg Hospital
Inflammatory Bowel Diseases
Tailored Therapeutic Model According to the Expression of Genes in Inflammatory Bowel Disease Patients
This study is a randomized controlled study conducted at five tertiary university hospitals. Patients who are 20-80 years old, diagnosed as having Inflammatory Bowel Disease(IBD) and who are planned to start thiopurines for the…
- Trial name
- NCT03719118
- Testing
- genotyping for three genes (TPMT, NUDT15 and FTO), non-genotyping
- Where
- 5 sites in South Korea
- Volunteers
- 215 people
- Sponsor
- Yonsei University
Aortic Aneurysm
Patient Tailored Contrast Volume for Preoperative CT Angiography of the Aorta
An in-house calculator was developed to calculate the appropriate contrast dose, rather than standardly administering a 120ml dose.
- Trial name
- NCT05716568
- Testing
- Contrast dose reduction, CT-angiography
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
ADHD
An Internet-delivered Intervention for Parents of Children With ADHD
The aims of the present study is to investigate the efficacy of a co-designed individually-tailored Internet intervention for parents of children with ADHD.
- Trial name
- ADHDCoach (NCT05341310)
- Testing
- ADHDCoach, Treatment as usual
- Where
- Romania
- Volunteers
- 86 people
- Sponsor
- Babes-Bolyai University
Lung Carcinoma
A Tailored Screening and Smoking Cessation Program for the LGBTQ Community of Seattle
This clinical trial develops a tailored screening and smoking cessation program for the lesbian, gay, bisexual, transgender (trans) and queer (LGBTQ) community of Seattle, Washington.
- Trial name
- NCT05304390
- Testing
- Patient Navigation, Questionnaire Administration, Smoking Cessation Intervention
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center