Clinical trials: Tailored Condition
Pain
Improvement the Anti-migraine Treatment Efficacy by Tailoring the Drug to Individual's Pain Modulation Profile
To delineate brain mechanisms that subserve endogenous analgesic (EA) in the healthy state. To identify alterations in mechanisms supporting EA in chronic pain (migraine) and their therapeutic relevance.
- Trial name
- NCT01470339
- Testing
- duloxetine
- Where
- Israel
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Blood Pressure
Tailored Interventions to Improve Hypertension Management After Stroke or Transient Ischemic Attack (TIA)
The purpose of this study is to determine the effectiveness of interventions to improve adherence to medication and healthier lifestyle choices on blood pressure over a 6 month period in a group of people at high risk for…
- Trial name
- TIMSII (NCT01038375)
- Testing
- lifestyle counseling, home blood pressure monitoring
- Where
- 3 sites in Canada
- Volunteers
- 56 people
- Sponsor
- Hamilton Health Sciences Corporation
Breast Neoplasms
Mobile Health (mHealth) Black Women With Breast Cancer
This research study will test whether a series of video clips with breast cancer information improves knowledge of breast cancer, breast cancer treatment and living with breast cancer.
- Trial name
- NCT02463474
- Testing
- mHealth Intervention
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- University of Florida
Behavioral Difficulties
Brief Parent Training for Children With Behavioral Difficulties in Primary Care Settings
The goal of this two-armed randomized controlled trial is to investigate the effectiveness of a new, individually tailored, brief behavioral training for parents of children with behavioral difficulties in general practitioners'…
- Trial name
- PAINT-POH (NCT06160193)
- Testing
- Brief behavioral parent training with optional care as usual, Care as usual
- Where
- Netherlands
- Volunteers
- 60 people
- Sponsor
- Accare
Cataract (Post-operative Cataract Surgery Follow-up), Refraction Error
Can Tailored Surgical Incisions Reduce Refractive Error and Dependence on Glasses After Cataract Surgery?
Astigmatism is a common cause of continued dependence on glasses after cataract surgery and may lead to patient dissatisfaction with surgical outcomes.
- Trial name
- AST-2 (NCT07623317)
- Testing
- Adapted clear corneal incisions
- Volunteers
- 100 people
- Sponsor
- Linkoeping University
Skin Cancer
Skin Cancer Prevention in a Pediatric Population
Skin cancer risk is largely determined by sun exposure during childhood. This study determines the effectiveness of a mailed intervention designed to increase sun protection for children age 6-9 years old.
- Trial name
- NCT01464957
- Testing
- Semi-tailored newsletter
- Where
- United States
- Volunteers
- 867 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Prostate Cancer
Culturally Tailored Decision Aid for Hispanic Patients Diagnosed With Prostate Cancer
A pilot study testing the effect of an in-visit English and Spanish language decision aid for Hispanic-Latino men using best practices of cultural tailoring to be used in urology practice.
- Trial name
- NCT03157947
- Testing
- Decision Aid Tool, baseline survey, follow-up surveys
- Sponsor
- Case Comprehensive Cancer Center
Colorectal Neoplasms
Randomized Controlled Trial of Tailored Interactive Multimedia to Reduce Colorectal Cancer Screening Disparities
The study investigators have developed an interactive multimedia computer program that provides personally tailored education about colorectal cancer screening in the user's preferred language (English or Spanish).
- Trial name
- NCT00786747
- Testing
- Personally tailored computer program, Non-tailored control computer program
- Where
- 5 sites in United States
- Volunteers
- 1,164 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Pain, Chronic, Loneliness
The Loneliness Epidemic Tailoring Interventions to Reduce Loneliness and Pain
Approximately 24% of community-dwelling older adults are socially isolated, and over 40% of adults 60 and older report feeling lonely.
- Trial name
- NCT05387447
- Testing
- Conversational Voice Assistant (Enhanced), Conversational Voice Assistant (Standard)
- Where
- 4 sites in United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Anatomic Stage IV Breast Cancer AJCC v8, Metastatic Breast Carcinoma
MBC Physical Activity Study
This clinical trial evaluates the impact of a tailored physical activity program on physical activity in patients with breast cancer that has spread from where it first started to other places in the body (metastatic).
- Trial name
- NCT06500858
- Testing
- Exercise Intervention, Health Promotion and Education, Internet-Based Intervention
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Thomas Jefferson University
Social Interaction, Schizophrenia Spectrum and Other Psychotic Disorders
Personalizing Interventions Using Real-World Interactions
Social functioning deficits are among the most disabling and difficult to treat aspects of schizophrenia. An essential component of social functioning is metacognition-a process that is profoundly disrupted in schizophrenia and…
- Trial name
- NCT04665401
- Testing
- Tailored MERIT, Standard MERIT
- Volunteers
- 34 people
- Sponsor
- Indiana University
Older Adults, Gastro-Intestinal Cancer
PeRsonalizing the Approach to the Oncologic Frail Individual Through Tailored Assessment and Intervention (PROFIT Study)
The PROFIT study has two complementary aims. The first aim is to compare, in a cohort study enrolling N=257 older adults (>65 years) with lung, gastrointestinal and prostate cancer, different easy measures of frailty (Geriatric 8…
- Conditions
- Older Adults, Gastro-Intestinal Cancer, Prostate Cancer, Lung Cancer
- Trial name
- PROFIT (NCT05319145)
- Testing
- Intervention group, Control group
- Where
- 3 sites in Andorra, Spain
- Volunteers
- 268 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Pain, Postoperative, Chronic Pain
Online Mindfulness-based Intervention to Prevent Chronic Pain
Cardiac and orthopedic surgeries are frequent procedures. However, pain after a major surgery may become chronic (lasting >3 months) in adults.
- Conditions
- Pain, Postoperative, Chronic Pain, Pain Catastrophizing, Pain, Acute
- Trial name
- NCT04848428
- Testing
- Online mindfulness-based cognitive therapy, Online standardized education
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Florida State University
Colorectal Cancer
Personalizing Chemotherapy Selection After Surgery for Patients With Stage III Colorectal Cancer Using a Blood Test
CIRCULATE-III is an international, multicenter, open-label, randomized phase III trial designed to use ctDNA as a selection criterion for intensification or de-escalation of adjuvant chemotherapy.
- Trial name
- CIRCULATEIII (NCT07340567)
- Testing
- Capecitabine, Oxaliplatin, Folfirinox
- Where
- 5 sites in France, Sweden
- Volunteers
- 2,450 people
- Sponsor
- UNICANCER
Crohn's Disease, Active, Crohn's Disease (CD)
Tailored Anti-Inflammatory American Diet for Patients With Crohn's Disease
The purpose of this study is to test the effect of an anti-inflammatory diet tailored for patients living in the United States with Crohn's Disease (CD) on clinical symptoms and disease inflammation and to identify biomarkers of…
- Conditions
- Crohn's Disease, Active, Crohn's Disease (CD), Diet Interventions
- Trial name
- NCT07671872
- Testing
- Catered Anti-Inflammatory Diet, Diet Guidance for Usual Diet
- Where
- United States
- Volunteers
- 122 people
- Sponsor
- University of Miami
Substance Use, HIV Prevention
Pre-implementation Study to Develop Trans-tailored Services for Transgender Persons in Relation to chemsEX
The study is a pre-implementation cross-sectional study exploring chemsex behaviors among transgender persons and gathering perspectives from multiple stakeholders to inform the development of transgender-tailored harm reduction…
- Conditions
- Substance Use, HIV Prevention, Sexually Transmitted Infections (STIs)
- Trial name
- T-REX (NCT07505875)
- Testing
- Understanding of chemsex patterns, impacts, and service needs among transgender persons
- Where
- Thailand
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Institute of HIV Research and Innovation Foundation, Thailand
Breast Cancer
Feasibility of a Modular mHealth for Tailored Rehabilitation of Breast Cancer
This study investigated the feasibility of the novel modular mobile health (mHealth) for personalized rehabilitation and explored the participants' satisfaction and app data during treatment of breast cancer.
- Trial name
- MMHTR (NCT04781712)
- Testing
- Modular mHealth for Tailored Rehabilitation
- Where
- South Korea
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Deafness
Perceptual Consequences of Cochlear Implant Electrode-neuron Interfaces
Despite the success of cochlear implants, devices surgically placed in the inner ears of patients with severe hearing loss, there remains substantial variability in the overall speech perception outcomes for the children and…
- Trial name
- NCT05867173
- Testing
- Experimental Speech Processing Strategy
- Where
- 2 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Massachusetts Eye and Ear Infirmary
HIV/AIDS, Smoking Cessation
Learn to Quit-HIV Pilot Study
The study team will conduct a feasibility, acceptability, and preliminary efficacy trial comparing Learn to Quit-HIV (n=30) to an app based on U.S.
- Conditions
- HIV/AIDS, Smoking Cessation, Tobacco Use Disorder
- Trial name
- NCT04609514
- Testing
- Learn to Quit-HIV, QuitGuide, Nicotine patch
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Duke University
Congestive Heart Failure
Health Literacy in Patients With Congestive Heart Failure
The primary aim of this project is to test the efficacy of an inpatient congestive heart failure (CHF) educational intervention compared with usual care among inpatients at Griffin Hospital, who are largely drawn from the…
- Trial name
- NCT00508716
- Testing
- Health Literacy-Tailored Education
- Where
- United States
- Volunteers
- 124 people
- Sponsor
- Griffin Hospital