Clinical trials: Takayasu Arteritis
Giant Cell Arteritis, Takayasu Arteritis
Biologics in Refractory Vasculitis: A Trial of Biologic Therapy for Refractory Primary Non-ANCA Associated Vasculitis
Vasculitis occur when the body's immune system, rather than protecting the body, attacks blood vessels, causing injury to the vessel and the part of the body it supplies with blood.
- Conditions
- Giant Cell Arteritis, Takayasu Arteritis, Cogan Syndrome, Relapsing Polychondritis
- Trial name
- BIOVAS (NCT05168475)
- Testing
- Rituximab, Infliximab, Tocilizumab
- Where
- 5 sites in United Kingdom
- Volunteers
- 22 people
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Takayasu Arteritis, Cardiovascular Diseases
Cardiovascular Risk in Patients With Takayasu Arteritis: A Nationwide Population-Based Cohort Study
This nationwide observational cohort study compares the risk of major adverse cardiovascular events (MACE) and territory-specific arterial complications between patients with incident Takayasu arteritis and matched…
- Trial name
- TAK-CV-2026 (NCT07686991)
- Where
- 2 sites in France
- Volunteers
- 8,275 people
- Sponsor
- Groupe français d'étude des Maladies Inflammatoires de loeil
Takayasu Arteritis
Takayasu Arteritis Clinical Trial in China
To investigate the efficacy and safety of Leflunomide (LEF) versus placebo combined with prednisone for active Takayasu arteritis (TAK) in Chinese population.
- Trial name
- TACTIC (NCT02981979)
- Testing
- Leflunomide(LEF), Prednisone Acetate Tablets
- Where
- 6 sites in China
- Volunteers
- 116 people
- Sponsor
- Jiang lindi
Takayasu Arteritis (TAK)
The Efficacy and Safety of Deucravacitinib in Takayasu's Arteritis
This is a 24-week, single-center, randomized, open-label trial conducted by Peking Union Medical College Hospital. The aim of this study is to assess the efficacy and safety of deucravacitinib in adult patients with relapsing TAK…
- Trial name
- NCT07013838
- Testing
- Deucravacitinib, Adalimumab
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Chinese SLE Treatment And Research Group
Takayasu Arteritis (TAK), Vasculitis, Systemic
Evaluation of Platelet Aggregability in Patients with Takayasu's Arteritis
Inflammatory syndromes in general, and primary vasculitis specifically, present a high risk of cardiovascular involvement. Takayasu arteritis (TAK), for example, presents cardiovascular complications in up to 60% of cases.
- Trial name
- PLATE (NCT06807788)
- Testing
- Clopidogrel
- Where
- Brazil
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Jose Carlos Nicolau
Takayasu's Arteritis
A Registry Study on Biomarkers of Takayasu's Arteritis (ARSBTA)
Takayasu arteritis is a chronic vasculitis mainly involving the aorta and its main branches such as the brachiocephalic, carotid, subclavian, vertebral, and renal arteries, as well as the coronary and pulmonary arteries.
- Trial name
- NCT03372980
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Beijing Institute of Heart, Lung and Blood Vessel Diseases
Takayasu Arteritis
Comparison of Mycophenolate Mofetil and Cyclophosphamide for Active Takayasu's Arteritis
Takayasu's arteritis(TAK) is a rare systemic vasculitis which can cause ischemia or inflammation of the involved organs and increase the overall mortality rate.The traditional treatment of TAK is primarily empirical.
- Trial name
- CommittedTA (NCT03096275)
- Testing
- MMF, CYC, Glucocorticoids
- Where
- 7 sites in China
- Volunteers
- 138 people
- Sponsor
- Chinese SLE Treatment And Research Group
Rheumatoid Arthritis, Ankylosing Spondylitis
Induction of Regulatory t Cells by Low Dose il2 in Autoimmune and Inflammatory Diseases
TRANSREG will assess the safety and biological efficacy of low-dose IL2 as a Treg inducer in a set of 14 autoimmune and auto-inflammatory diseases, with the aim to select diseases in which further therapeutic development will be…
- Conditions
- Rheumatoid Arthritis, Ankylosing Spondylitis, Systemic Lupus Erythematosus, Psoriasis
- Trial name
- TRANSREG (NCT01988506)
- Testing
- Interleukin 2
- Where
- 11 sites in France
- Volunteers
- 81 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Takayasu's Arteritis
Clinical Study of Anti-tumor Necrosis Factor Therapy in Patients With Takayasu Arteritis
Clinical study of anti-tumor necrosis factor therapy in patients with Takayasu arteritis. This study is single arm (anti Tumor necrosis factor therapy only) clinical trial. Enrolled patients will be 11
- Trial name
- NCT02457585
- Testing
- remicade (anti tumor necrosis factor inhibitor)
- Where
- South Korea
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Takayasu Arteritis, Behcet Disease
Turkish Adaptation of the VascuQoL-6 Quality of Life Scale
Study type: Observational study Primary objective: The aim of this study was to examine the validity and reliability of the Vascular Quality of Life Questionnaire-6 (VascuQoL-6) in Turkish in individuals diagnosed with Takayasu…
- Conditions
- Takayasu Arteritis, Behcet Disease, Quality of Life
- Trial name
- NCT06979245
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 37 people
- Sponsor
- Uşak University
Takayasu's Arteritis
Exercise in Juvenile Takayasu Disease
Juvenile Takayasu disease is characterized by chronic inflammation that leads to vascular disease. Exercise may render anti-inflammatory effects and protect against cardiovascular events.
- Trial name
- NCT03494062
- Testing
- Exercise
- Where
- Brazil
- Volunteers
- 21 people
- Sponsor
- University of Sao Paulo
Purpura, Schoenlein-Henoch, Graft Versus Host Disease
Autologous Peripheral Blood Stem Cell Transplantation in Patients With Life Threatening Autoimmune Diseases
OBJECTIVES: I. Determine whether there is prompt engraftment after autologous peripheral blood stem cell transplantation using filgrastim (G-CSF) mobilization in patients with life threatening autoimmune diseases. II.
- Conditions
- Purpura, Schoenlein-Henoch, Graft Versus Host Disease, Anemia, Hemolytic, Autoimmune, Rheumatoid Arthritis
- Trial name
- NCT00006055
- Testing
- anti-thymocyte globulin, cyclophosphamide, cyclosporine
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Fairview University Medical Center
Takayasu's Arteritis, Giant Cell Arteritis
Carotid Artery Neovascularization in Takayasu's and Giant Cell Arteritis
The purpose of this study is to evaluate the ability of contrast enhanced carotid ultrasound to serve as an indicator of disease activity in patients with Takayasu's arteritis or Giant Cell arteritis and to determine if patients…
- Conditions
- Takayasu's Arteritis, Giant Cell Arteritis, Arteritis, Vasculitis
- Trial name
- NCT01795456
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Behcet's Disease, Churg-Strauss Syndrome
Educational Needs of Patients With Systemic Vasculitis
A cross-sectional study design and online questionnaire was used to assess the informational needs of patients with several different types of systemic vasculitis.
- Conditions
- Behcet's Disease, Churg-Strauss Syndrome, Vasculitis, Central Nervous System, Giant Cell Arteritis
- Trial name
- NCT02190929
- Where
- United States
- Volunteers
- 386 people
- Sponsor
- University of South Florida
Takayasu Arteritis, Takayasu Arteritis (TAK)
Investigating Management, Perspectives and Attitudes Towards Care in Takayasu Arteritis
This study aims to understand the experiences of patients with Takayasu arteritis (TAK) and how physicians manage the condition.
- Trial name
- TAK-IMPACT (NCT07351422)
- Testing
- Questionnaire
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- University of Edinburgh
Takayasu Arteritis
Impact and Utility of PET Versus Clinical Score for the Assessment of Inflammatory Activity in Takayasu Arteritis
The purpose of this study is to demonstrate that [18F]FDG PET is a a better method than clinical and laboratory values for the identification and assessment of inflammatory activity in patients with Takayasu Arteritis (TA)…
- Trial name
- NCT01532167
- Where
- Mexico
- Volunteers
- 26 people
- Sponsor
- Instituto Nacional de Cardiologia Ignacio Chavez
Takayasu Arteritis With Pulmonary Artery Involvement, Percutaneous Transluminal Pulmonary Angioplasty
Treatment of Patients With Takayasu Arteritis Complicated With Pulmonary Artery Involvement
1. Evaluate the effect of medical treatment and percutaneous transluminal pulmonary angioplasty on takayasu arteritis with pulmonary artery involvement 2.
- Conditions
- Takayasu Arteritis With Pulmonary Artery Involvement, Percutaneous Transluminal Pulmonary Angioplasty, PAH Targeted Medication
- Trial name
- NCT05388682
- Testing
- Percutaneous transluminal pulmonary angioplasty
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Chinese Pulmonary Vascular Disease Research Group
Takayasu Arteritis
Biologic Treatment Withdrawal in Takayasu Arteritis Patients in Sustained Remission
Takayasu arteritis is a chronic large-vessel vasculitis affecting the aorta and its major branches. Biologic therapies such as tumor necrosis factor inhibitors and tocilizumab are commonly used in patients with refractory or…
- Trial name
- NCT07491913
- Testing
- Tociliuzumab, Infliximab, Adalimumab
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Marmara University
Takayasu Arteritis With Pulmonary Artery Involvement, Pulmonary Arterial Hypertension Associated With Connective Tissue Disease
Clinical Features and Prognosis of Takayasu's Arteritis With Pulmonary Arteries Involvement
The purpose of this study is to identify the clinical features, management pattern and long-term outcomes of patients with pulmonary arteries involvement in Takayasu's arteritis (TAK-PAI).
- Trial name
- CAPTAIN (NCT07184814)
- Where
- China
- Volunteers
- 150 people
- Sponsor
- China-Japan Friendship Hospital
Takayasu Arteritis
Surgery Benefits Takayasu Arteritis With Stenosis in the Descending Aorta
The long-term prognosis and optimal management for Takayasu arteritis(TA) patients with severe stenosis of the descending thoracic and abdominal aorta remain undefined.
- Trial name
- NCT07149805
- Testing
- open surgery or interventional treatment
- Volunteers
- 78 people
- Sponsor
- Peking Union Medical College Hospital