Clinical trials: Takotsubo Syndrome
Pericarditis, Tako-TSUBO Cardiomyopathy
Inflammatory Disease Biobank for Immunophenotyping and Cardiovascular Research
INFLAME-BANK is a French multicenter prospective observational ancillary study of the international EACVI-INFLAME project. It aims to establish a biobank and perform immunophenotyping and proteomic analyses in patients with…
- Conditions
- Pericarditis, Tako-TSUBO Cardiomyopathy, Myocarditis, Inflammatory Cardiomyopathies
- Trial name
- INFLAME-BANK (NCT07737470)
- Volunteers
- 300 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Takotsubo Cardiomyopathy, Acute Coronary Syndrome
Effectiveness of a Resilience-Based Rehabilitation Program for Patients With Coronary Heart Disease
To handle daily life challenges, one needs to be psychologically resilient. It plays a crucial role in disease development, prognosis, as well as social, occupational, and community participation.
- Conditions
- Takotsubo Cardiomyopathy, Acute Coronary Syndrome, Psychological Resilience
- Trial name
- NCT06332859
- Testing
- Resilience training
- Where
- Austria
- Volunteers
- 130 people
- Sponsor
- Pensionsversicherungsanstalt
Myocarditis, ANCA Associated Vasculitis
EACVI Study on Multimodality Cardiovascular Imaging of Inflammatory Cardiovascular Diseases
Inflammatory Cardiovascular Diseases and Autoimmune Rheumatic Diseases (ICARDs) encompass cardiovascular involvement in connective tissue diseases, vasculitis, and primary inflammatory cardiac processes affecting all layers of…
- Conditions
- Myocarditis, ANCA Associated Vasculitis, Pericarditis, Systemic Sclerosis
- Trial name
- EACVI-INFLAME (NCT07077304)
- Testing
- observational study
- Where
- France
- Volunteers
- 5,000 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Takotsubo Syndrome
Autonomic Modulation in Takotsubo Syndrome
This is a minimal risk case-controlled single arm intervention study, including 10 patients with a prior history of takotsubo and 10-age and sex matched healthy controls.
- Trial name
- NCT03324529
- Testing
- Tako Breath
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- NYU Langone Health
Takotsubo Cardiomyopathy, Broken Heart Syndrome
Registry of Patients With Takotsubo Syndrome
Takotsubo syndrome is a condition which mimics acute myocardial infarction, and is diagnosed in 1.5% to 2.2% of patients referred to hospital with suspected acute coronary syndrome.
- Conditions
- Takotsubo Cardiomyopathy, Broken Heart Syndrome, Tako-tsubo Cardiomyopathy
- Trial name
- NCT03663348
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- NYU Langone Health
Takotsubo Syndrome
The GErman Italian Spanish Takotsubo (GEIST) Registry
GEIST is a multicenter, international observational registry of patients with Takotsubo syndrome. Data regarding the clinical profile (demographic characteristics, clinical presentation, laboratory measures, electrocardiography…
- Trial name
- GEIST (NCT04361994)
- Where
- 2 sites in Germany, Italy
- Volunteers
- 500 people
- Sponsor
- Prof. Dr. med. Ingo Eitel
Stroke, Myocardial Injury
Mechanisms And Prognosis of Stroke-Heart Syndrome
The incidence of stroke-heart syndrome following acute stroke, which encompasses both acute ischemic stroke and acute intracerebral hemorrhage, is notably high and is strongly associated with increased mortality and poor outcomes…
- Conditions
- Stroke, Myocardial Injury, Heart Failure, Acute Coronary Syndromes
- Trial name
- MAP-SHS (NCT06954103)
- Where
- China
- Volunteers
- 658 people
- Sponsor
- Chensheng Pan
Takotsubo Syndrome
BROKEN-SWEDEHEART- Optimized Pharmacological Treatment for Broken Heart (Takotsubo) Syndrome.
The aim of this study is to document an optimized pharmacologic treatment for patients with Takotsubo Syndrome. There is currently no published documentation in a large number of patients.
- Trial name
- NCT04666454
- Testing
- Adenosine, Dipyridamole 200 mg, Apixaban 5 mg Oral Tablet
- Where
- 16 sites in Denmark, Norway and 1 more
- Volunteers
- 1,000 people
- Sponsor
- Vastra Gotaland Region
Takotsubo Syndrome
Italian Multicenter Observational Registry on Takostubo Syndrome
Takotsubo syndrome (TTS) has recently been described as an acquired form of cardiomyopathy whose pathophysiology is not yet well understood and mainly affects postmenopausal women.
- Trial name
- TIN (NCT06643949)
- Testing
- Echocardiography
- Volunteers
- 1,500 people
- Sponsor
- University of Molise
Takotsubo Cardiomyopathy, Beta-blockers
Beta-Blockers in Takotsubo Syndrome Study
The Beta-blockers in Takotsubo syndrome (TTS) (β-Tako) trial, is an academic, pragmatic, prospective, multicenter randomized clinical trial, aiming to assess the efficacy of beta-blockers (BB) in TTS patients.
- Conditions
- Takotsubo Cardiomyopathy, Beta-blockers, Echocardiography, Left Ventricular Function
- Trial name
- β-Tako (NCT06509074)
- Testing
- Beta blocker
- Where
- Spain
- Volunteers
- 200 people
- Sponsor
- Spanish Society of Cardiology
Myocardial Depression, Takotsubo Syndrome
Predicting the Development of Myocardial Depression in Acute Neurological Patients
The purpose of this study is to assess the levels of serum catecholamines associated with myocardial depression (MD) in patients with acute neurological injury.
- Conditions
- Myocardial Depression, Takotsubo Syndrome, Subarachnoid Hemorrhage, Acute Ischemic Stroke
- Trial name
- NCT03801694
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Ohio State University
Takotsubo Syndrome
Takotsubo Syndrome and Air Pollution
Takotsubo syndrome (TTS) is an acute and reversible form of myocardial injury characterized by typical regional wall motion abnormalities in the absence of culprit epicardial coronary artery disease frequently precipitated by…
- Trial name
- Tako-Air (NCT05731830)
- Testing
- Data extraction, Clinical follow-up
- Where
- Italy
- Volunteers
- 250 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Takotsubo Syndrome
Optimized Characterization of Takotsubo Syndrome by Obtaining Pressure Volume Loops
Aim of this prospective study is to assess the pathophysiology of Takotsubo Syndrome by obtaining pressure volume loops with conductance catheters, which allows detailed conclusions regarding systolic and diastolic hemondynamics…
- Trial name
- OCTOPUS (NCT03726528)
- Testing
- Measurements of left ventricular pressure and volume
- Where
- Germany
- Volunteers
- 25 people
- Sponsor
- University of Luebeck
Takotsubo Cardiomyopathy
Long-term Echocardiographic Findings in Takotsubo Syndrome
Takotsubo syndrome (TTS) is characterized by severe left ventricular (LV) dysfunction that gradually recovers, thus leading to the commonly accepted belief that it is a transient and self-limiting condition.
- Trial name
- LONG-TAKE (NCT05084157)
- Testing
- Echocardiography
- Volunteers
- 500 people
- Sponsor
- University of Roma La Sapienza
Takotsubo Syndrome
Polish Registry of Takotsubo Syndrome
Polish registry of takotsubo syndrome
- Trial name
- Pol-Tako (NCT04634487)
- Testing
- No intervention
- Where
- Poland
- Volunteers
- 1,000 people
- Sponsor
- Medical University of Warsaw
Left Ventricular Dysfunction, Critically Ill
Left Ventricular Dysfunction in Critically Ill Patients
Left ventricular dysfunction is common in the critically ill. The aim of this study is to assess the incidence and prognosis of left ventricular dysfunction in critically ill patients.
- Conditions
- Left Ventricular Dysfunction, Critically Ill, Acute Coronary Syndrome, Cardiomyopathies
- Trial name
- LEVEDYCIP (NCT03787810)
- Testing
- Echocardiography
- Where
- Sweden
- Volunteers
- 428 people
- Sponsor
- Sahlgrenska University Hospital
Myocardial Necrosis, Tako Tsubo Syndromes
French Observatory Syndromes Tako-Tsubo
Tako Tsubo syndrome (TTS) is characterized by the occurrence in the context of mental or physical stress, a clinical and ECG of acute myocardial infarction without significant coronary artery stenosis, accompanied by a disorder…
- Trial name
- OFSETT (NCT01252004)
- Where
- France
- Volunteers
- 121 people
- Sponsor
- French Cardiology Society
Takotsubo Cardiomyopathy, Takotsubo Syndrome
Adenosin to Rapidly Reverse Left Ventricle Impairment in Takotsubo Syndrome
The investigators will randomize patients admitted to hospital with Takotsubo diagnosis to systematic high-dose adenosine infusion for 3 minutes (in addition to standard of care) vs. standard of care.
- Trial name
- TITAN (NCT02867878)
- Testing
- Adenosine, Saline solution
- Where
- Italy
- Volunteers
- 5 people
- Sponsor
- University Hospital of Ferrara
Takotsubo Cardiomyopathy, Cardiac X Syndrome
Brain-heart Interactions in Tako-Tsubo Cardiomyopathy and Cardiac Syndrome X:
The Tako-Tsubo Cardiomyopathy (TTC) and the Cardiac Syndrome X (CSX) are respectively acute and chronic heart diseases, which mimic myocardial infarction and stable angina pectoris without alterations of large coronary vessels.
- Conditions
- Takotsubo Cardiomyopathy, Cardiac X Syndrome, Acute Myocardial Infarction
- Trial name
- BRAINHEART (NCT02759341)
- Testing
- Manual for the Assessment and Documentation of Psychopathology (AMDP 8), Million Clinical Multiaxial Inventory 3 (MCMI-III), State-Trait Anxiety Inventory form Y (STAI-Y)
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- Ospedale San Giovanni Bellinzona
Tako-TSUBO Cardiomyopathy, Acute Coronary Syndrome
TAKO-TSUBO Cardiomyopathy and Genetic
This is a case-control association study with multicentric prospective recruitment. Tako-TSUBO cardiomyopathy is a new clinical entity mimicking an acute coronary syndrome.
- Trial name
- NCT01520610
- Where
- France
- Volunteers
- 530 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris