Clinical trials: Tandem Occlusion
Acute Stroke, Ischemic Stroke, Acute
Rescue Extracranial Vertebral Stenting in Tandem Occlusions
The acute vertebrobasilar occlusion associated with the poor prognosis, particularly tandem occlusion. However, few data on the efficacy of the endovascular therapy was indicated in this occlusion.
- Conditions
- Acute Stroke, Ischemic Stroke, Acute, Vertebro Basilar Ischemia
- Trial name
- REVET (NCT06365294)
- Testing
- Rescue extracranial stenting
- Where
- Vietnam
- Volunteers
- 9 people
- Sponsor
- Dr. Cuong Tran Chi
Carotid Artery Stenosis
Gao's Triple Eversion Carotid Endarterectomy
Carotid endarterectomy (CEA), an important surgical approach for managing carotid plaque, has evolved over more than 70 years but still cannot be applied to all tandem carotid lesions (TCLs) because of the wide range of these…
- Trial name
- NCT06722222
- Testing
- Gao's triple eversion carotid endarterectomy
- Where
- China
- Volunteers
- 11 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Acute Stroke, Ischemic Stroke, Acute
Tandem Occlusion After Emergent Stenting in Acute Ischemic Stroke
In acute ischemic stroke due to tandem occlusion, the emergent stenting has recently become an endovascular treatment option combining with mechanical thrombectomy to achieve recanalization.
- Trial name
- TOESIS (NCT06120218)
- Testing
- Emergent Stenting
- Where
- Vietnam
- Volunteers
- 110 people
- Sponsor
- Can Tho Stroke International Services Hospital
Ischemic Stroke, Tandem Occlusion
Safety, Tolerability and Efficacy of Adjunctive TBO-309 in Reperfusion for Stroke With Tandem Occlusion
Co-STAR is a multicenter, prospective, open-label, Bayesian Optimal Phase 2 (BOP2) trial that aims to assess the safety and efficacy of adjunctive intravenous TBO-309 in Acute Ischaemic Stroke (AIS) patients with tandem occlusion…
- Trial name
- Co-STARS (NCT06813651)
- Testing
- TBO-309: 60 mg, TBO-309: 120 mg, TBO-309: 30 mg
- Where
- 2 sites in Australia
- Volunteers
- 78 people
- Sponsor
- ThromBio Pty. Ltd.
Hydronephrosis; Obstruction, Ureter, Renal Failure
Tandem Polyurethane Stents Compared to Single Silicone Stent for Malignant Ureteral Obstruction
Malignant ureteral obstruction (MUO) is an extrinsic ureteral obstruction caused by malignant diseases. This study aim to compare tandem 6 Fr Percuflex™ stents and single large-caliber 8Fr silicone stent in patients with MUO.
- Conditions
- Hydronephrosis; Obstruction, Ureter, Renal Failure, Malignancy, Ureter Obstruction
- Trial name
- TSTENT (NCT05992363)
- Testing
- ureteral stent\s insertion
- Where
- 2 sites in Israel
- Volunteers
- 106 people
- Sponsor
- Rabin Medical Center
Acute Stroke, Ischemic Stroke, Acute
Rescue Carotid Stenting in Tandem Occlusions: 4-year Experience From a Comprehensive Stroke Centre
The rescue carotid stenting has recently been an additional treatment followed by mechanical thrombectomy in tandem occlusions of the anterior circulation.
- Trial name
- NCT06397638
- Testing
- Rescue carotid stenting
- Where
- Vietnam
- Volunteers
- 90 people
- Sponsor
- Can Tho Stroke International Services Hospital
Acute Ischemic Stroke
Proximal Internal Carotid Artery Acute Stroke Secondary to Tandem or Local Occlusion Thrombectomy Trial
The primary objective is to establish the efficacy of intra-arterial (IA) mechanical thrombectomy (MT) with extracranial proximal carotid artery acute stenting versus non-stenting approaches in patients with acute ischemic stroke…
- Trial name
- PICASSO (NCT05611242)
- Testing
- MT+CAS with IV-AP, MT+CAS with PO-AP, MT+CAT with PO-AP
- Where
- 60 sites in United States
- Volunteers
- 404 people
- Sponsor
- Mercy Health Ohio
Thrombectomy, Tandem Occlusion
Stent Implantation Versus Balloon Dilation for Acute Anterior Circulation Tandem Occlusion
1. To evaluate whether stent implantation on the ipsilateral extracranial segment, after intracranial thrombectomy successful recanalization compared with balloon angioplasty (eTICI≥2b_50) for acute anterior circulation tandem…
- Conditions
- Thrombectomy, Tandem Occlusion, Stroke
- Trial name
- START (NCT05902000)
- Testing
- Carotid Stenting, Thrombectomy, Dual antiplatelet treatment
- Where
- China
- Volunteers
- 222 people
- Sponsor
- Xueli Cai
Coronary Artery Disease
Single Long vs Two Short Overlapping Bioabsorbable Polymer DES
Multiple overlapping drug-eluting coronary stents (DES) are usually needed to treat long coronary stenoses but this strategy is expensive and the response to overlapping DES has not been extensively studied.
- Trial name
- ROCCO (NCT01718106)
- Testing
- implantation of a bioabsorbable polymer DES
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- Azienda Ospedaliero Universitaria Maggiore della Carita
Carotid Artery Diseases, Thrombectomy
Thrombectomy In TANdem Occlusion
Tandem occlusion is defined by an acute ischemic stroke (AIS) with concomitant steno-occlusive disease of the extra cranial carotid artery and concerned about 10% of AIS patients.
- Conditions
- Carotid Artery Diseases, Thrombectomy, Tandem Occlusion, Stroke
- Trial name
- TITAN (NCT03978988)
- Testing
- Carotid Stenting, Procedural Aspirin, Dual dual antiplatelet therapy after 24-hours imaging follow-up
- Where
- France
- Volunteers
- 432 people
- Sponsor
- Central Hospital, Nancy, France
Stroke, Acute, Carotid Stenosis
Endovascular Acute Stroke Intervention - Tandem OCclusion Trial
Patients with tandem occlusion or tandem lesion (TL), that is, stroke with an acute intracranial anterior circulation occlusion and an ipsilateral cervical ICA (c-ICA) high-grade stenosis or occlusion, constitute about 15-20% of…
- Conditions
- Stroke, Acute, Carotid Stenosis, Carotid Artery Diseases
- Trial name
- EASI-TOC (NCT04261478)
- Testing
- Carotid artery stenting, Antiplatelet Agents
- Where
- Canada
- Volunteers
- 458 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Coronary Artery Disease, Cardiovascular Diseases
Functional Diagnostic Accuracy of Quantitative Flow Ratio in Tandem Lesions and Virtual Stenting
Quantitative Flow Ratio (QFR) is a novel method for evaluating the functional significance of coronary stenosis. Virtual stent implantation technique combined with QFR was recently developed to predict the functional significance…
- Conditions
- Coronary Artery Disease, Cardiovascular Diseases, Myocardial Ischemia, Arterial Occlusive Diseases
- Trial name
- FORTRESS (NCT03405506)
- Testing
- Quantitative Flow Ratio (QFR)
- Where
- China
- Volunteers
- 308 people
- Sponsor
- Pulse Medical Imaging Technology (Shanghai) Co., Ltd
Stroke, Acute
Embolectomy in Acute SYlvian Thrombosis in Refractory or Ineligible Patients to ALteplase
This trial aims at comparing two strategies currently used to address acute ischemic stroke of the middle cerebral artery : medical treatment without endovascular treatment on the one hand, and medical treatment plus endovascular…
- Trial name
- EASY (NCT02216565)
- Testing
- Hospitalization in specialized neuro-vascular unit, Alteplase if patient is eligible, Supportive care
- Where
- 3 sites in France
- Volunteers
- 2 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Acute Stroke With Large Vessel Occlusion
Stent Thrombosis After Tandem Lesions Thrombectomy
The aim is to describe the rate of delayed stent thrombosis after endovascular management of consecutive tandem lesions, in a patient series with systematic follow-up of stent patency.
- Trial name
- DST-TANDEM (NCT03588780)
- Where
- France
- Volunteers
- 80 people
- Sponsor
- University Hospital, Strasbourg, France
Acute Ischemic Stroke Related to Tandem Occlusion, Acute Ischemic Stroke Due to Isolated Cervical Artery Occlusion
Risk Factors and Outcomes of Ischemic Stroke Associated With Tandem or Isolated Cervical Artery Occlusion in Anterior and Posterior Circulation
CERES-TANDEM is a multicenter study designed to improve the understanding of "tandem" ischemic stroke -those caused by two blockages in series, one in a neck artery and one in a brain artery-.
- Trial name
- CERES-TANDEM (NCT06965036)
- Where
- 3 sites in United States, Italy and 1 more
- Volunteers
- 2,880 people
- Sponsor
- Azienda Unità Sanitaria Locale della Romagna