Clinical trials: Taste, Altered
Taste Perception, Fixed Orthodontic Appliances
Taste Changes With Fixed Orthodontic Appliances
The aim of this research: 1. To analyze the possible influence of fixed orthodontic appliances on taste perception among patients undergoing conventional orthodontic treatment. 2.
- Trial name
- NCT06093256
- Testing
- Fixed orthodontic appliances
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Riyadh Elm University
Saliva Altered, Taste, Altered
Astringency and Oral Health
The perception of astringency is thought to involve the interaction between tannins and salivary proteins. However, the mechanisms underlying this interaction are poorly understood.
- Trial name
- NCT05819073
- Testing
- Plain water, CPE
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Multiple Myeloma (MM), GI Cancer
Gustabor Phase 2 - Treating Taste Changes During Cancer Therapy: A Randomized Study Evaluating an AI- Based Nutrition Intervention
The study investigates taste disorders that commonly occur during or after cancer treatment, often leading to issues such as malnutrition and treatment discontinuation.
- Conditions
- Multiple Myeloma (MM), GI Cancer, Taste Disorder, Melanoma (Skin Cancer)
- Trial name
- GustaborRCT (NCT07649681)
- Testing
- Gustabor server, Standard Recommendations
- Where
- 6 sites in Germany
- Volunteers
- 198 people
- Sponsor
- Wuerzburg University Hospital
Dysgeusia, Head and Neck Cancer
Zinc Sulfate in Preventing Loss of Sense of Taste in Patients Undergoing Radiation Therapy for Head and Neck Cancer
RATIONALE: It is not yet known whether zinc sulfate is effective in preventing the loss of ability to taste food in cancer patients who are undergoing radiation therapy for head and neck cancer.
- Conditions
- Dysgeusia, Head and Neck Cancer, Oral Complications, Radiation Toxicity
- Trial name
- NCT00036881
- Testing
- zinc sulfate
- Volunteers
- 173 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Anorexia, Cachexia
Bovine Lactoferrin Supplement in Improving Taste in Patients With Cancer Receiving Chemotherapy
This pilot phase II trial studies how well bovine lactoferrin supplement works in improving taste in patients with cancer receiving chemotherapy.
- Conditions
- Anorexia, Cachexia, Malignant Neoplasm, Oral Complications of Chemotherapy
- Trial name
- NCT01941810
- Testing
- bovine lactoferrin supplement, questionnaire administration, quality-of-life assessment
- Where
- 2 sites in United States
- Volunteers
- 14 people
- Sponsor
- Wake Forest University Health Sciences
Taste Disorders
Changes in Sense of Taste of Patients Submitted to Hematopoietic Stem Cell Transplantation
During conditioning with chemotherapy and radiotherapy for the transplantation of hematopoietic stem cells (HSCT), oral changes, such as mucositis, xerostomia infections and dysgeusia may occur.
- Trial name
- NCT03498950
- Testing
- laser therapy
- Volunteers
- 80 people
- Sponsor
- Fernanda de Paula Eduardo
Post Operative Nutrition
Changes in Taste Perception and Preference in the Peri-operative Patient
It is well known that patients who have undergone major surgical procedures are vulnerable to the consequences of inadequate calorie or nutritional intake.
- Trial name
- TASTE (NCT02154841)
- Testing
- Questionnaire, taste test, visual food test
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- University Hospital Plymouth NHS Trust
Altered Taste
TQ-PAL Development and Validation
Taste problems are common among patients with advanced cancer. These symptoms can affect the pleasure of eating and drinking, reduce dietary intake, cause low mood, and a lower quality of life.
- Trial name
- NCT06588933
- Testing
- completion of a questionnaire
- Where
- Ireland
- Volunteers
- 200 people
- Sponsor
- Prof Andrew Davies
Oncology, Taste, Altered
Assessment of ONS-flavour Preference in Cancer Patients With and Without Taste Alterations
A single arm intervention study examining ONS-flavour preference in cancer patients with and without taste alterations
- Trial name
- PREFER (NCT05518825)
- Testing
- Fortimel/Nutridrink Compact Protein
- Where
- Netherlands
- Volunteers
- 64 people
- Sponsor
- Nutricia Research
Orthognathic Surgery, Altered Taste
Change in Taste Sensation After Orthognathic Surgery
Orthognathic surgery refers to jaw operations that can be performed on the upper jaws (Le Fort I osteotomy) and lower jaws (Sagittal Split Ramus osteotomy).
- Trial name
- NCT06103422
- Testing
- Whole mouth taste tests, Localized taste tests
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Yağmur Malkoc
Diet, Healthy, Obesity
Olfactory and Taste Changes During Fasting Mimicking Diet (FMD)
Literature experiences demonstrated the impact of medically-assisted pulsed fasting on olfactory behavior in both the animal and human models and - conversely - the lack of homogeneous results linked - up to now - to…
- Conditions
- Diet, Healthy, Obesity, Olfaction Disorders
- Trial name
- FMD1 (NCT04529161)
- Testing
- Fasting Mimicking Diet (FMD), Routinary diet habits
- Where
- Italy
- Volunteers
- 102 people
- Sponsor
- Uniter Onlus
Epilepsy
An Open-Label, Safety and Tolerability Study of Chronic Intermittent Use of Diazepam Nasal Spray.
This study will assess long-term safety and tolerability of repeat dose diazepam nasal spray in adolescents and adults with cluster seizures, with a focus on potential local effects (changes in nasal mucosa, olfaction, and taste).
- Trial name
- NCT02316847
- Testing
- diazepam nasal spray
- Where
- 33 sites in United States
- Volunteers
- 126 people
- Sponsor
- Acorda Therapeutics
Testicular Cancer
Taste, Smell and Chemotherapy (TASTY)
Taste and smell abnormalities are common in cancer patients undergoing chemotherapy, with a prevalence ranging from 46% to 77% for taste changes, and 35% to 75% for smell changes.
- Trial name
- TASTY (NCT01641172)
- Testing
- Dexa scan, audiogram, measurement of heart rate variability and baroreflex sensitivity
- Where
- Netherlands
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University Medical Center Groningen
Appetite, Taste, Altered
Impact of Acute Resistance Exercise on Taste Perception and Appetite Response to Plant Protein in Resistance Trained Adults
Some evidence suggests that taste perception might be modulated by physical exercise, with differences observed after aerobic exercise (DOI:10.1093/chemse/23.4.417) and with habitual exercise (DOI:10.3390/nu11010155).
- Conditions
- Appetite, Taste, Altered, Exercise
- Trial name
- NCT06089993
- Testing
- Exercise, Rest
- Where
- Ireland
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University College Dublin
Taste, Altered
Fatty Acid Taste Rating With or Without Sour Taste Adaptation
We are trying to figure out whether the fatty acid taste is differentiated from sour taste.
- Trial name
- NCT04248374
- Testing
- Taste Intensity
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Purdue University
Multiple Myeloma
LI-TASTE Study: Light for Taste
Rationale: In 2020, 115,000 Dutch patients were diagnosed with cancer. Up to 85% of patients treated with radiotherapy involving the head and neck, chemotherapy or stem-celltransplantation (SCT) suffer from taste disorders…
- Trial name
- LI-TASTE (NCT06258096)
- Testing
- LX2.3 Laser and LED Photobiomodulation System
- Volunteers
- 52 people
- Sponsor
- Academic Centre for Dentistry in Amsterdam
Taste, Altered
Relationship Between MUC1 Expression and Gustatory Function in Postmenopausal Females
50 females will be included in this study. they will be divided into 2 groups (study group which will include 25 postmenopausal females - and control group which will include premenopausal females) For testing gustatory function…
- Trial name
- NCT04606524
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- October 6 University
Taste, Altered
Taste Changes With Bariatric Surgery
It is commonly believed that a link exists between BMI and taste perception. One group of researchers observed that women who are obese experience reduced taste sensitivity when compared to normal-weight controls.
- Trial name
- NCT03548038
- Testing
- taste test
- Where
- 2 sites in United States
- Volunteers
- 21 people
- Sponsor
- University of Missouri-Columbia
Chemotherapy Side Effects, Taste, Altered
Taste Alterations Study
The main questions it aims to answer are: 1. Does completing a standard assessment increase the detection of chemotherapy induced taste changes compared with usual care (no assessment)? What TA are experienced? Are there any…
- Trial name
- TAS (NCT06669416)
- Testing
- Taste Alteration Self-Assessment, Taste Alternation Self-Management
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Wake Forest University Health Sciences
Gingivitis, Periodontitis
The Impact of Non-surgical Periodontal Therapy on Patients' Halitosis, Taste Perception, and Smell Sensation
The goal of this observational study is to evaluate the effect of non-surgical periodontal treatment on patient halitosis, smell, and taste perception in gingivitis and periodontitis patients.
- Trial name
- NCT06063460
- Testing
- Periodontal examination, baseline questionnaire about sociodemographic characteristics, smoking habits, oral hygiene habits, halitosis, smell and taste perception, phase I periodontal treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people
- Sponsor
- Necmettin Erbakan University