Clinical trials: Taste Perception
SARS-CoV Infection, COVID-19
Malaysian COVID-19 Anosmia Study (Phase 1) - A Nationwide Multicentre Cross-Sectional Study
The Malaysian COVID-19 Anosmia Study is a nationwide multicentre observational study to investigate the prevalence and characteristics of olfactory and gustatory/taste disturbances in COVID-19 infection in Malaysia, and to…
- Conditions
- SARS-CoV Infection, COVID-19, Anosmia, Dysgeusia
- Trial name
- NCT04390165
- Testing
- Patient-Reported Online Questionnaire on Olfactory & Taste Disturbances
- Where
- 14 sites in Malaysia
- Volunteers
- 498 people
- Sponsor
- Hospital Sultanah Bahiyah
Head and Neck Cancer, Taste Dysfunction
Addressing Taste Dysfunction With Miraculin in Head and Neck Cancer Patients Receiving Radiation Therapy
Patients diagnosed with head and neck cancer who receive radiation therapy with and without chemotherapy develop altered sense of taste due to treatment effect, which typically arises in the second week of radiation therapy and…
- Trial name
- NCT05273307
- Testing
- Miraculin
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of California, San Francisco
Altered Taste
TQ-PAL Development and Validation
Taste problems are common among patients with advanced cancer. These symptoms can affect the pleasure of eating and drinking, reduce dietary intake, cause low mood, and a lower quality of life.
- Trial name
- NCT06588933
- Testing
- completion of a questionnaire
- Where
- Ireland
- Volunteers
- 200 people
- Sponsor
- Prof Andrew Davies
Immunotherapy Gastroesophageal Junction
The Efficacy and Safety of Tislelizumab Combined With Anlotinib and S1 Plus Oxaliplatin as Neoadjuvant Therapy for the Locally Advanced Adenocarcinoma of Esophagogastric Junction
To evaluate the efficacy and safety of tislelizumab combined with antilotinib and SOX regimen for neoadjuvant treatment of locally advanced esophagogastric junction cancer
- Trial name
- NCT06396585
- Testing
- Tislelizumab, Anlotinib, Oxaliplatin
- Where
- China
- Volunteers
- 28 people
- Sponsor
- Fujian Cancer Hospital
Nutritional Physiological Phenomena
Gene Polymorphism of Taste Receptors and Circulating Endocannabinoids in Normal Weight and Obese Subjects
The study aims at evaluating in normal weight and obese subjects those factors such as taste sensitivity and circulating endocannabinoids in influencing dietary choice and thereby lipid and energy metabolism in order to design…
- Trial name
- NCT02729584
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of Cagliari
COVID-19 Respiratory Infection
Oral Symptoms of COVID-19 Among Infected Medical Doctors
Oral symptoms of corona virus disease have been reported by many studies. The lack of direct contact between the dentist and the patient during the active disease presented an obstacle to build a strong body of evidence.
- Trial name
- NCT05697081
- Testing
- Medical doctors infected with COVID-19
- Where
- Egypt
- Volunteers
- 312 people, healthy volunteers welcome
- Sponsor
- Beni-Suef University
Hereditary Tyrosinemia, Type I
Taste and Palatability of Orfadin Suspension
The purpose of this study is to verify that pediatric patients, especially those who are not old enough to swallow capsules, accept the taste and palatability of a new suspension.
- Trial name
- NCT01734889
- Testing
- Nitisinone
- Where
- 7 sites in France, Germany and 1 more
- Volunteers
- 18 people
- Sponsor
- Swedish Orphan Biovitrum
Rhinosinusitis
Allele-specific Expression of a Bitter Taste Receptor
This single-site, within-subject experimental basic research study is designed to analyze the hypothesis that allele-specific expression of the bitter taste receptor T2R38 in taste tissue of individuals heterozygous for the taste…
- Trial name
- NCT02766959
- Testing
- Observational study
- Where
- 3 sites in United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Monell Chemical Senses Center
Appetitive Behavior, Weight Loss
Understanding the Effects of Water-related Appetite Expectancies on Caloric Intake in College Students
Consuming large volumes of water has recently been identified as a common weight loss strategy among U.S. adults. It is a widespread belief that drinking water increases feelings of satiety and reduces food intake, which could…
- Conditions
- Appetitive Behavior, Weight Loss, Water, Energy Intake
- Trial name
- NCT04737629
- Testing
- Expectancy and Water, No Expectancy and Water, No Water
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Florida
Stroke, Dysphagia
Taste Stimulation for Post-stroke Dysphagia
The goal of this clinical study is to compare the effect of favourate taste stimulation of oral cavity and tounge, with sour and traditional single thermal stimulation in post-stroke patients with dysphagia.
- Trial name
- NCT05989100
- Testing
- Favourate taste stimulation, Sour taste stimulation, Thermal stimulation group
- Where
- 2 sites in China
- Volunteers
- 87 people
- Sponsor
- Qilu Hospital of Shandong University
Lean Body Mass, Cannabis
The Effect of Cannabidiol on Lean Body Mass in Patients Receiving Chemotherapy
An intervention study on the effect of cannabidiol on lean body mass in cancer patients receiving chemotherapy, at the department of Clinical Oncology at Zealand University Hospital, Roskilde, Denmark.
- Conditions
- Lean Body Mass, Cannabis, Cancer, Nausea
- Trial name
- NCT04585841
- Testing
- Cannabidiol
- Where
- Denmark
- Volunteers
- 32 people
- Sponsor
- University of Copenhagen
Decay, Dental
Effect of Natural Antibacterial Mouthwash on Taste, Salivary pH and Bacteria in High Caries Risk pt
Evaluate the effect of propolis extract mouthwash and pomegranate extract mouthwash on taste alteration, salivary pH and antibacterial activity against streptococcus mutans in high caries risk patients.
- Trial name
- NCT03623048
- Testing
- chlorhexidine, saline, Propolis extract
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Cairo University
Obesity, Obstructive Sleep Apnoea Syndrome
Study of Eating Behaviour and Sense of Taste Before and After Treatment With Nocturnal Continuous Positive Airway Pressure in Overweight Patients With Obstructive Sleep Apnea Syndrome.
Obstructive sleep apnea (OSA) is characterized by a repeated partial or complete obstruction of the airway that results in a intermittent hypoxia and sleep disturbance.
- Trial name
- GOUSAS (NCT03701737)
- Testing
- questionnaires, wrist actimeter, Blood samples
- Where
- France
- Volunteers
- 94 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Pediatric Obesity
Children's Taste Study to Increase Vegetable Intake in Preschoolers
Studies have shown that when exposed to a variety of food and flavor options people tend to consume more than when only one item is presented.
- Trial name
- CTS (NCT03043118)
- Testing
- Variety Intervention
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Penn State University
Food Preferences
Improving Protein Intake in Older Adults
To evaluate whether or not high quality protein intake from a mixed meal can be increased by using culinary herbs and spices to increase flavor intensity and food item liking in older adults.
- Trial name
- NCT05175391
- Testing
- Meat based protein with added spice; Plant based protein with added spice
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Sensory Testing, Umami Taste Perception
Effect of Umami Exposure on MSG Induced-satiation
Monosodium Glutamate (MSG) is an amino acid salt that naturally enhances umami taste in many foods. It is often used to reduce salt (NaCl) in products while keeping the flavour.
- Conditions
- Sensory Testing, Umami Taste Perception, Food Intake Regulation
- Trial name
- RISE (NCT06725615)
- Testing
- Regular Umami exposure, High Umami exposure, Low Umami exposure
- Where
- Netherlands
- Volunteers
- healthy volunteers welcome
- Sponsor
- Wageningen University
Sensory Testing
Sensory and Hedonic Effects of FAAA-conjugates Added to Food Products
Rationale: According to preliminary observations provided by the research and development department (R\&D) of Givaudan, addition of specific fatty acid-amino acid (FAAA)-conjugates to a wide range of food products resulted in an…
- Trial name
- NCT03787394
- Testing
- adding taste enhancer
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Wageningen University
Energy Density
Palatability (Energy I Pilot)
A pilot study was conducted to develop the study menus that were similar in appearance, aroma, and taste.
- Trial name
- NCT01653886
- Testing
- Breakfast (1-2 hours, in the morning), Lunch (1-2 Hours, at midday), Dinner (1-2 hours, in the afternoon)
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Melanoma, Non-small Cell Lung Cancer (NSCLC)
Taste and Smell Dysfunction in Patients More Than Two Years After Start of Immune Checkpoint Inhibitor Therapy
Background of the study: Immune checkpoint inhibitors (ICIs) are widely used as treatment for multiple cancer types and the number of patients with longterm disease control after ICIs is increasing.
- Conditions
- Melanoma, Non-small Cell Lung Cancer (NSCLC), Urogenital Cancers
- Trial name
- TasteSPICIER (NCT06495008)
- Testing
- no intervention, only questionnaires, saliva collection and taste/smell tests
- Where
- Netherlands
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- University Medical Center Groningen
Healthy
Genetic Variability in Taste Perception
This proposal describes a pilot study aimed at determining whether genetic variations in taste receptors determine differential taste tolerability of pediatric medications.
- Trial name
- NCT01841710
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Monell Chemical Senses Center