Clinical trials: Taurine
Oxidative Stress
Normal Values of Oxidative Stress, Taurine, and Related Markers
The role of oxidative stress in disease pathology is increasingly recognized. At present, the development of biomarkers of this state is in its infancy and the availability of clinically validated assays is lacking.
- Trial name
- NCT02649777
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Radiation Induced Oral Mucositis, Radiodermatitis
Taurine's Therapeutic Effect on Acute Radiation-induced Oral Mucositis and Dermatitis
This is a single-center, double-blind, randomized controlled study. The patients were divided into control group and experimental group, 80 cases each.
- Trial name
- NCT07029178
- Testing
- Taurine granule
- Where
- China
- Volunteers
- 160 people
- Sponsor
- Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
Gastric Cancer
Clinical Study of Taurine Combined With Sintilimab and Chemotherapy for Treatment of Advanced Gastric Cancer
This project aims to evaluate the efficacy and safety of oral taurine supplementation combined with PD-1 inhibitor (sintilimab) and chemotherapy in inducing systemic CD8+ T cell responses and achieving improved gastric cancer…
- Trial name
- NCT06123455
- Testing
- Taurine, Sintilimab, XELOX regimen
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Tang-Du Hospital
Thalassemia Major
Thalassemic Iron Overload Cardiomyopathy is Ameliorated by Taurine Supplementation
Hypothesis: Taurine, in combination with standard iron chelation therapy, is more effective than chelation therapy alone in reducing cardiac iron overload, oxidative stress and cardiac damage in β-Thalassemia.
- Trial name
- TICATS (NCT04291352)
- Testing
- Taurine
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University Health Network, Toronto
Cardiovascular Risk
Clinical Trial on the Effects of Caffeine and Taurine From Energy Drinks (EDs) to Parameters of the Cardiovascular System in Humans
The aim of this study is to examine the safety and the effects of EDs at high doses, either alone or in combination with other risk factors such as alcohol intake, physical exercise and sleep deprivation, on cardiovascular…
- Trial name
- NCT01421979
- Testing
- Energy Drink, Taurine, Caffeine
- Where
- Germany
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Hohenheim
Prehypertension
Effects and Safety of Taurine Granule on Blood Pressure in Prehypertensive
Prehypertension are associated with an increased risk of atherosclerosis and coronary artery disease, and often complicated with the metabolic disorder of glucose and lipid.
- Trial name
- ESTAB (NCT01816698)
- Testing
- Taurine granule
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Zhiming Zhu
Pain, Acute, Pain, Chronic
Butyrate and Taurine for Chronic Postsurgical Pain in Adult Cardiac Surgical Patients
This study is a single-center, phase II, randomized, placebo-controlled, Bayesian-designed, double-blinded trial Goal and Questions: The primary goal is to evaluate if a combination of taurine and butyrate can reduce chronic…
- Conditions
- Pain, Acute, Pain, Chronic, Chronic Post Operative Pain
- Trial name
- NCT07144033
- Testing
- Butyrate and Taurine
- Where
- Hong Kong
- Volunteers
- 216 people
- Sponsor
- Chinese University of Hong Kong
Bipolar Disorder
Taurine in Adolescents With Bipolar Disorder
Recently, McLean hospital conducted a 4 month taurine study which showed a reduction in mania ratings. As a follow-up to the preliminary taurine study, and complementary to the currently ongoing double-blind, placebo-controlled…
- Trial name
- NCT00391001
- Testing
- Taurine
- Where
- 2 sites in United States
- Volunteers
- 4 people
- Sponsor
- Cambridge Health Alliance
Alcohol-Related Disorders, Drinking and Driving
Interaction of Alcohol With Energy Drinks
The main objective of the project is to assess whether there is an interaction between the effects of ethanol and energy drinks on driving performance.
- Trial name
- AEDED (NCT02771587)
- Testing
- Alcohol and energy drink, Alcohol, Energy drink
- Where
- 2 sites in Spain
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Parc de Salut Mar
To Evaluate the Safety of Taurine in Preventing Acute Radiation Skin Injury Induced by Adjuvant Radiotherapy in Breast Cancer Patients
Phase I-II Clinical Study of Taurine for External Use in the Prevention and Treatment of Acute Radiation Skin Injury
Acute radiation skin injury is the most common side effect of radiation therapy in patients with chest tumors, which can be manifested as erythema, dry peeling, wet peeling, and severe ulcers.
- Trial name
- NCT06847555
- Testing
- Radiation
- Where
- China
- Volunteers
- 24 people
- Sponsor
- Shandong Cancer Hospital and Institute
Cataract
Taurine Eye Drops May Prevent the Progression of Cataract
The aim of the current intervention study is to determine the effectiveness of taurine containing eye drops (available under brand name VIZILOTON) to prevent the progression of grade I and II senile cataract.
- Trial name
- NCT06639711
- Testing
- Taurine
- Where
- Iraq
- Volunteers
- 50 people
- Sponsor
- University Of Anbar
Premature Birth
Total Parenteral Nutrition Associated Cholestasis (TPNAC) and Plasma Amino Acid Levels in Neonates
The purpose of this study is to analyze if the infants who received Primene solution, have lower serum levels of methionine and cysteine and higher serum levels of taurine, we also analyze if the infants who received Primene…
- Trial name
- TPNAC (NCT01062724)
- Testing
- Primene 10 % from Baxter
- Where
- Mexico
- Volunteers
- 94 people
- Sponsor
- Coordinación de Investigación en Salud, Mexico
Oxidative Stress
Taurine as a Possible Anti-aging Therapy?
Among the strategies that can improve the body's ability to counteract oxidative stress, the use of nutritional antioxidants has been investigated.
- Trial name
- NCT05149716
- Testing
- Taurine
- Where
- Brazil
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Bipolar Disorder, Mania
Taurine as an Anti-Manic Agent: A Double-Blind, Placebo-Controlled Study
The purpose of this study is to determine whether the amino acid taurine has effects on mood stability in bipolar disorder.
- Conditions
- Bipolar Disorder, Mania, Bipolar Depression
- Trial name
- NCT00217165
- Testing
- taurine
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Mclean Hospital
Colorectal Cancer
Study to Assess Colonic Microbiota Changes in Response to Energy Drink Consumption
This study will investigate whether short-term daily energy drink consumption results in an increase in hydrogen sulfide-producing bacteria in adults 18-40 years old.
- Trial name
- ROSANNA (NCT06137248)
- Testing
- Energy drink
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- University of Florida
Periodontitis
Effect of Amnion Membrane With and Without Taurine on GCF TNF α Level.
45 sites in 15 patients with periodontal pockets ≥ 5mm were selected. These selected sites were divided into 3 groups as Group A, B and C.
- Trial name
- NCT04772508
- Testing
- Scaling and root planing, Amnion membrane, Taurine
- Where
- India
- Volunteers
- 45 people
- Sponsor
- Maharishi Markendeswar University (Deemed to be University)
Diabetes Mellitus, Type 2
Taurine Effect on Glycemic, Lipidic and Inflammatory Profile in Individuals With Type 2 Diabetes
Type 2 diabetes mellitus (DM2) is characterized by chronic hyperglycemia, which is a risk factor for comorbidities and death. Although conventional pharmacotherapy is effective, some individuals do not reach the glycemic targets…
- Trial name
- TAUGLIP-DM2 (NCT04874012)
- Testing
- Active comparator Taurine
- Where
- Brazil
- Volunteers
- 94 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Taurine, Aging, Biological
Effects Of Daily Taurine Intake For 6 Months On Biological Age and Body Metabolism Indicators As Well As Physical Fitness In 55-75-year-old Women And Men
The goal of this clinical trial is to investigate the effect of taking 4 grams of taurine by older adults on aging processes over a period of 6 months.
- Conditions
- Taurine, Aging, Biological, Physical Activity, Metabolic Health
- Trial name
- TauAge (NCT06613542)
- Testing
- 4g of taurine daily
- Where
- Germany
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Psychotic Disorders
A Study of Taurine in Patients With First-episode Psychosis Receiving Antipsychotic Treatment
The purpose of this study is to determine whether Taurine 4g is effective with antipsychotic medication in the treatment of First Episode Psychosis.Taurine may have an effect on cognition and symptoms.
- Trial name
- NCT00420823
- Testing
- Taurine 4g
- Where
- 2 sites in Australia
- Volunteers
- 121 people
- Sponsor
- Melbourne Health
Obesity
Taurine Supplementation and Exercise on Irisin Levels in Obesity
Irisin is a myocin secreted by skeletal muscle in stimulus to physical exercise and has been described as a possible therapeutic tool in the fight against obesity by triggering a cascade of signaling that triggers the expression…
- Trial name
- NCT04646512
- Testing
- Physical training with Deep Water Running
- Where
- Brazil
- Volunteers
- 31 people
- Sponsor
- University of Sao Paulo