Clinical trials: Tear
Meniscal Tear
Nanoscope Cost Analysis Study
The study is a pilot study designed to generate preliminary data regarding the cost of partial meniscectomy using NanoScope versus conventional arthroscopy in a traditional operating room (OR) setting
- Trial name
- NCT06603740
- Testing
- Arthrex Nanoscope, Conventional Arthroscopy without Arthrex Nanoscope
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Arthrex, Inc.
ACL - Anterior Cruciate Ligament Rupture
Assessment of NEURO-K-STARTS Following Primary Anterior Cruciate Ligament (ACL) Reconstruction
Anterior cruciate ligament (ACL) reconstruction is the major treatment option for ACL injuries. Despite this, recurrence rates are high.
- Trial name
- NEURO-K-STARTS (NCT07659613)
- Testing
- NEURO-K-STARTS
- Where
- France
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Contact Lens Discomfort
The Effect of Eyelid Margin Debridement on Contact Lens Discomfort
In this study, clinical variables related to eyelids that potentially have an effect on contact lens discomfort will be investigated such as eyelid signs and secretions, eyelid sensitivity, eyelid microbiome, Demodex infestation…
- Trial name
- NCT03311204
- Testing
- BlephEx, Lid Hygenix
- Where
- Australia
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- The University of New South Wales
Rotator Cuff Tears, Shoulder Surgery
Regeneten Patch vs Standard Care in Partial Thickness Rotator Cuff Repair
Shoulder pain is a common complaint with the most common reason being tendinopathy and/or tearing of the rotator cuff. While many rotator cuff tears are often considered normal, age-related degenerative disorders, with either…
- Trial name
- NCT04673344
- Testing
- Regeneten Collagen Patch
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Rothman Institute Orthopaedics
Healthy, Dry Eyes
Topical Menthol For Tear Secretion
Tears are the natural way to keep eyes moist, and tears are important for good vision and healthy eyes. Eyes without enought tears get dry and sore.
- Trial name
- TMTS (NCT07109609)
- Testing
- Topical application of 20% menthol solution in MCT oil.
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Reinhold Vieth
Rotator Cuff Impingement Syndrome, Rotator Cuff Tendinitis
Analysis of the Effect of Neuromuscular Electro-stimulation on the Performance of Isometric Rotator Cuff Strength.
Introduction: Shoulder disorders are a common musculoskeletal problem causing pain and functional loss in different populations. Tendinopathies are a group of pathologies commonly diagnosed in patients with shoulder pain.
- Conditions
- Rotator Cuff Impingement Syndrome, Rotator Cuff Tendinitis, Subacromial Impingement Syndrome
- Trial name
- NCT06023914
- Testing
- STRENGTH EVALUATION WITH ELECTROSTIMULATOR, STRENGTH EVALUATION WITHOUT ELECTROSTIMULATOR
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Campinas, Brazil
Infra-orbital Hollows, Tear-trough Deformity
RHA® Redensity Eye Versus No-treatment for the Infra-Orbital Hollows
This is a multicenter, blinded evaluator, randomized, prospective, no treatment control clinical study to identify whether RHA® Redensity Eye (*) is superior to no treatment for the correction of moderate to severe tissue volume…
- Conditions
- Infra-orbital Hollows, Tear-trough Deformity, Wrinkle
- Trial name
- NCT04577898
- Testing
- RHA® Redensity Eye
- Where
- 4 sites in United States
- Volunteers
- 248 people, healthy volunteers welcome
- Sponsor
- Teoxane SA
Dry Eye Syndrome
Oral Nutrition Impact on Tear Film
Dry eye disease (DED) is a common but often inadequately treated disease of the tears and surface of the eye. It can cause poor vision and chronic pain and is more frequent with increasing age.
- Trial name
- ONIT (NCT01561040)
- Testing
- Omega 3, Vitamins A, D3 and E
- Where
- 4 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Eye and Vision Technologies and Research Institute
Rotator Cuff Injury, Anesthesia; Functional
The Impact of a Preoperative Nerve Block on the Consumption of Sevoflurane
Arthroscopic rotator cuff surgery of the shoulder is performed under general anesthesia. Pain control for after the surgery can be achieved purely with intravenous and oral pain medication or in combination with freezing of the…
- Trial name
- NCT03533452
- Testing
- Ropivacaine, Normal saline
- Where
- 2 sites in Canada
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Dry Eye
Tear Osmolarity Over Time With Artificial Tears
The effect of artificial tears on tear osmolarity
- Trial name
- NCT01227226
- Testing
- Artificial tears
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Hom, Milton M., OD, FAAO
Anterior Cruciate Ligament Injury, Anterior Cruciate Ligament Rupture
Functional and Self-reported Outcomes in Participants With a History of Musculoskeletal Knee Injury
Negative outcomes impact individuals with a history of ACL reconstruction (ACLR) despite completion of formal rehabilitation and clearance to return to physical activity (PA).
- Trial name
- NCT03617991
- Testing
- Exercise Group
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Johanna M. Hoch
Abdominal Aortic Aneurysm Without Rupture
ShorT Stay Aneurysm Repair Study
A prospective observational cohort study to assess the eligibility, uptake, viability, acceptability, safety, and cost of a ShorT stay (23-hour) Aneurysm Repair (STAR) pathway. Outcomes will be collected for up to 1 year.
- Trial name
- STAR (NCT05279274)
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Dry Eye
Tear Film Thickness Measured Using a Novel Technique
The aim of this investigation is to determine the thickness of the human preocular tear film using a new method based on laser speckle.
- Trial name
- NCT01014780
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Southern California College of Optometry at Marshall B. Ketchum University
Obstetric Perineal Rupture
Diagnosing Perineal Tears, Does Different Assessment Methods Affect the Midwife's Clinical Judgement of Perineal Tears?
This study aims to compare different midwife practitioners assessments of perineal tears.
- Trial name
- NCT01278979
- Testing
- Objective measurements of perineal tears with "Peri-Rule", Visual and digital assessment
- Where
- Norway
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Ostfold Hospital Trust
Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture
Treatment of Acute ACL Injuries in Young Patients Using a Rebound ACL Brace
This study evaluates the use of a brace in acute anterior cruciate ligament (ACL) injuries in children and adolescents. Half of the participants will receive a so called rebound ACL brace together with a standardized rehab…
- Conditions
- Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament Tear
- Trial name
- NCT04185532
- Testing
- Rebound ACL brace and physioterapy, Physioterapy
- Where
- Sweden
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Frida Hansson, MD
Preterm Membrane Rupture, Neonatal Sepsis
Comparison of the Effectiveness of Two Different Antibiotic Regimens of the Treatment of Pregnant Women With Preterm Rupture of Membranes
There is no consensus around the world on the treatment of preterm rupture of membranes, which is one of the important causes of early neonatal sepsis and one of the common causes of prematurity.
- Trial name
- NCT04528251
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Rotator Cuff Tear, Proximal Humerus Fractures
Clinical Outcome Comparison Between Medial and Lateral Offset Reverse Shoulder Arthroplasty
The purpose of this study is to prospectively evaluate two FDA approved implant designs for the Tornier Reverse Shoulder arthroplasty. The small difference in design is the amount of offset each implant has.
- Conditions
- Rotator Cuff Tear, Proximal Humerus Fractures, Malunions, Chronic Proximal Humerus Dislocations
- Trial name
- NCT01086202
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Rotator Cuff Injury, Pain
Pre-emptive Opioid Treatment to Prevent Rebound Pain After Arthroscopic Rotator Cuff Repair and/or Acromioplasty Under General Anesthesia and Interscalene Block
Arthroscopic shoulder rotator cuff repair and acromioplasty are associated with severe postoperative pain. The interscalene block (ISB) is commonly used for this type of surgery, providing analgesia by anesthetizing the nerves…
- Trial name
- NCT02939209
- Testing
- Hydromorphone Hcl 2Mg Tab
- Where
- 2 sites in Canada
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Vishal Uppal
Tear Trough Hollowing, Under Eye Bags
Platelet Rich Fibrin for Tear Trough Rejuvenation
The purpose of this study is to investigate the efficacy and longevity of Platelet Rich Fibrin (PRF) in combination with hyaluronic acid filler for cosmetic volume restoration of the tear troughs.
- Trial name
- NCT03313934
- Testing
- Hyaluronic Acid Filler and Platelet Rich Fibrin (PRF), Hyaluronic Acid Filler and Saline
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Rejuva Medical Aesthetics
Supraspinatus Tear
Mesenchymal Stem Cells and Amniotic Membrane Composite for Supraspinatus Tendon Repair Augmentation
This is a non-randomized clinical trial conducted in a single tertiary hospital which investigates the efficacy of allogeneic adipose-derived mesenchymal stem cells and human amniotic membrane (AAdMSC-HAM) composite for…
- Trial name
- NCT04670302
- Testing
- Tendon repair procedure, Tendon repair augmented with AAdMSC-HAM composite
- Where
- Indonesia
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Dr. Soetomo General Hospital