Clinical trials: Tear Break-Up Time
Dry Eye Syndromes
Treatment of Dry Eye With Supplements
Dry eye syndrome (DES) is a highly prevalent ocular condition inducing an inflammatory response on the ocular surface. Common symptoms include ocular discomfort, visual impairment and instability of the tear film with potential…
- Trial name
- NCT01364311
- Testing
- Vitamac® Tag and Nacht capsules
- Where
- Austria
- Volunteers
- healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Dry Eye, Tear Break-Up Time
Compare the Clinical Efficacy of 3% Diquafosol and 0.1% Hyaluronic Acid in Patients with Dry Eye After Trans-PRK
The prevalence of refractive ametropia is rising year by year. Refractive surgery has become the main approach for adults to correct refractive ametropia, and postoperative complications have aroused extensive attention from…
- Trial name
- NCT06852105
- Testing
- 3% Diquafosol Sodium Eye Drops, 0.1% hyaluronic acid
- Volunteers
- 76 people
- Sponsor
- He Eye Hospital
Dry Eye Syndrome
Correlation of Different Signs for Assessment of Dry Eye Syndrome
Dry eye syndrome (DES) is a highly prevalent ocular condition inducing an inflammatory response of the ocular surface. Common symptoms include ocular discomfort, visual impairment and instability of the tear film with potential…
- Trial name
- NCT01753687
- Testing
- Ocular scattering of the tear film, Optical Coherence Tomography (OCT), Measurement of tear film osmolarity
- Where
- Austria
- Volunteers
- 50 people
- Sponsor
- Medical University of Vienna
Keratoconjunctivitis Sicca
Effect of Controlled Adverse Environment (CAE) on Tear Film Stability
The purpose of this study is to evaluate the effect of the controlled adverse environment (CAE) on Mean Break-Up Area in subjects diagnosed with Dry Eye Syndrome.
- Trial name
- NCT01547936
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- ORA, Inc.
Dry Eye
Evaluation of Extended Tear Film Break Up Time (TFBUT) With an Ocular Emulsion
The primary objective of this investigation will be to quantify the increase in tear film break-up time (TFBUT) associated with the instillation of a single eyedrop of an Ocular Emulsion in dry eye sufferers.
- Trial name
- NCT01368198
- Testing
- Systane Balance Lubricating Eye Drops, OPTIVE™
- Where
- 2 sites in United States, United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Alcon Research
Dry Eye, Acupuncture
Medical vs Acupuncture for Dry Eye
This randomized clinical trial was designed to evaluate the effectiveness of acupuncture combined with artificial tears compared to artificial tears alone in patients with moderate dry eye disease.
- Trial name
- ADET (NCT07185854)
- Testing
- Artificial tears, Traditional Chinese Medicine Acupuncture
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Nadide Koca
Corneal Injury, Exposure Keratopathy
Eyelid Taping Alone Versus Taping With Lubricant Eye Drops for Perioperative Corneal Protection
During general anesthesia, the eye's natural protective reflexes are suppressed, which can lead to corneal drying and injury. To prevent this, anesthesiologists routinely tape the eyelids closed.
- Conditions
- Corneal Injury, Exposure Keratopathy, Perioperative Complications
- Trial name
- NCT07562594
- Testing
- Hypoallergenic Eyelid Taping, Hypoallergenic Eyelid Taping With Lubricant Eye Drops
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Dry Eye Syndrome (DES), Hand Osteoarthritis
Ocular Surface Disease Index and Dry Eye Parameters in Hand Osteoarthritis
This study investigates whether the relationship between the Ocular Surface Disease Index (OSDI) and dry eye parameters can be used as a predictive marker in patients diagnosed with hand osteoarthritis.
- Trial name
- NCT07789054
- Testing
- Dry Eye and Ocular Surface Assessments
- Where
- Turkey (Türkiye)
- Volunteers
- 23 people
- Sponsor
- Medipol University
Dry Eye
Keratometric Tear Breakup Time and Fluorescein Tear Breakup Time
The purpose of the research is to determine if putting fluorescein onto the eye (most common test done for dry eye syndrome) is an accurate way to measure dry eye symptoms.
- Trial name
- NCT00854906
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Arkansas
Dry Eye
Efficacy and Safety Study of FID 119515A
The purpose of this study was to compare the effect of FID 119515A to Blink® Tears on the integrity of tear film in adults with a history of dry eye in both eyes.
- Trial name
- NCT01833117
- Testing
- FID 119515A, Blink® Tears
- Volunteers
- 75 people
- Sponsor
- Alcon Research
Corneal Topography, Dry Eye Syndromes
Performance Evaluation of the OCUTOP Hand-held Corneal Topographer
The OCUTOP is a new hand-held camera that photographs the front of the eye to map the shape of the cornea and to assess the tear film.
- Conditions
- Corneal Topography, Dry Eye Syndromes, Keratoconus, Healthy Volunteers
- Trial name
- OCUTOP (NCT07895849)
- Testing
- OCUTOP hand-held corneal topographer with OCUGRAPH software, Reference instrument measurement (corneal topography and tear-film assessment)
- Where
- 2 sites in United Kingdom
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Plymouth
Visual Fatigue, Dry Eye
Evaluation of New Color Temperature Adjustment Mode in Preventing Dry Eye and Visual Fatigue
The purpose of this study was to investigate the effects of visual fatigue and dry eye level under different correlated color temperature modes, and to evaluate the effect of new designed dynamic color temperature change modes on…
- Trial name
- NCT07201493
- Testing
- color temperature change mode
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Beijing Tongren Hospital
Intraocular Pressure (IOP), Tear Break-Up Time
Efficacy and Safety of Three Different Latanoprost 0,005% Eyedrops in Subjects Affected by Primary Open Angle Glaucoma
This study examines efficacy and tolerability of 3 different Latanoprost 0.005% eyedrops preparations, commercially available in Italy, in subjects affected by primary open angle glaucoma.
- Trial name
- LATANOPROST (NCT01580254)
- Testing
- IOPIZE© Latanoprost eyedrops, GALAXIA© Latanoprost eyedrops, Latanoprost RATIOPHARM© latanoprost eyedrops
- Where
- Italy
- Volunteers
- 120 people
- Sponsor
- University of Catanzaro
Dry Eye Syndromes
Acupuncture for Dry Eye Syndrome
This study is about the effectiveness of acupuncture treatment on dry eye syndrome. Study hypothesis is that a standardized acupuncture would be more effective than a sham acupuncture in dry eye syndrome patients.
- Trial name
- NCT00969280
- Testing
- Standardized Acupuncture, Non-acupuncture point shallow penetration acupuncture
- Where
- South Korea
- Volunteers
- 42 people
- Sponsor
- Korea Institute of Oriental Medicine
Eye Diseases, Ocular Surface Disease
Effect on Ocular Surface Symptoms of Online Education
retrospective, observational study.
- Conditions
- Eye Diseases, Ocular Surface Disease, Dry Eye
- Trial name
- NCT04960696
- Testing
- OSDI, tear break up time, schirmer
- Where
- Turkey (Türkiye)
- Volunteers
- 315 people
- Sponsor
- Kahramanmaras Sutcu Imam University
Dry Eye Syndrome
Assessment of Tear Film Thickness by Optical Coherence Tomography in Healthy Subjects and Subjects With Dry Eye Disease
Dry eye syndrome (DES) is a highly prevalent ocular condition with severe consequences for the patients reaching from ocular discomfort in its simplest form up to visual impairment and corneal ulceration in severe cases.
- Trial name
- NCT01753596
- Testing
- GENTEAL HA® Eye Drops (NOVARTIS, Switzerland), Physiological Sodium Chloride solution (0,9%)
- Where
- Austria
- Volunteers
- healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Dry Eye
Dry Eye Evaluation After Transepithelial PRK
The aim of the study is to evaluate the severity of dry eye syndrome following excimer laser vision correction using no-touch all-laser photorefractive keratectomy in comparison to conventional lasik
- Trial name
- NCT02210793
- Testing
- transepithelial PRK, LASIK
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- AL-Nour Eye Hospital
Dry Eye
Clinical Outcomes Following Treatment With Systane® Balance in Dry Eye Subjects
The purpose of this study is to demonstrate the superior efficacy of Systane® Balance over Preservative-Free 0.9% Saline following 35 days of QID (4 times a day) dosing in treating dry eye subjects with lipid deficiency.
- Trial name
- NCT01967147
- Testing
- Propylene Glycol, 0.6% eye drops, Preservative-free 0.9% Saline solution
- Volunteers
- 279 people
- Sponsor
- Alcon Research
Meibomian Gland Dysfunction
The Efficacy of an Ocular Emulsion in Meibomian Gland Dysfunction
The aim of this study will be to determine the efficacy of this novel, lipid-containing artificial tear on the signs and symptoms of meibomian gland disease.
- Trial name
- NCT01207752
- Testing
- Systane Balance, Optive Lubricant Eye Drops
- Where
- United States
- Volunteers
- 69 people
- Sponsor
- Southern California College of Optometry at Marshall B. Ketchum University
Myopia, Hyperopia
Subjective Comparison of Pre-Lens Tear Film Stability With Daily Disposable Contact Lenses
The purpose of this study was to compare three CE-marked daily disposable contact lenses for tear film stability as measured by pre-lens non-invasive keratograph break up time (PL NIK-BUT).
- Conditions
- Myopia, Hyperopia, Refractive Error
- Trial name
- NCT01839318
- Testing
- Nelfilcon A contact lenses, Omafilcon A contact lenses, Etafilcon A contact lenses
- Volunteers
- 30 people
- Sponsor
- Alcon Research