Clinical trials: Teen Pregnancy
Endometriosis
IUD and Norethindrone Acetate for Treatment of Endometriosis
Endometriosis is the most common reproductive disease afflicting young women, often leading to debilitating chronic pelvic pain and impaired quality of life.
- Trial name
- NCT04948489
- Testing
- norethindrone acetate (NETA)
- Where
- United States
- Sponsor
- Boston Children's Hospital
Transgenderism, Kidney Diseases
Effect of Hormone Therapy on Renal Function
The purpose of this study is to understand the effects of testosterone or estradiol on kidney function in transgender adolescents and young adults.
- Conditions
- Transgenderism, Kidney Diseases, Kidney Injury
- Trial name
- NCT04482920
- Testing
- p-aminohippurate clearance study, Iohexol infusion
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of Colorado, Denver
HIV Infections, Pregnancy Related
Reaching 90 90 90 in Adolescents in Zambia: Using All Our SKILLZ
"SKILLZ," is a mixed methods evaluation of the Grassroots Soccer (GRS) SKILLZ Package based in Lusaka, Zambia. The package is made up of three football-based programs: (1) SKILLZ-Girl - implemented in schools as part of a 10-week…
- Conditions
- HIV Infections, Pregnancy Related, STI, Mental Health Wellness 1
- Trial name
- SKILLZ (NCT04429061)
- Testing
- SKILLZ-Girl curriculum
- Where
- Zambia
- Volunteers
- 2,153 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Type 1 Diabetic Nephropathy
The Impact of Sitagliptin as an Add on Therapy With Closed Loop Control in Adolescents With Diabetic Nephropathy
Diabetic nephropathy (DN) is one of the most frequent microvascular complications of diabetes mellitus, affecting 25 to 40% of patients with type 1 diabetes (T1DM).
- Trial name
- NCT06115460
- Testing
- oral sitagliptin supplementation
- Where
- Egypt
- Volunteers
- 46 people
- Sponsor
- Ain Shams University
Preterm Birth
Adolescents Born Preterm; Nurtured Beginnings
This research study is a long-term follow-up to an earlier study of developmental care. For that study, high risk preterm newborns were randomly assigned to a standard care group, which received the standard care offered in the…
- Trial name
- NCT00310869
- Testing
- Individualized Developmental Care in the NICU
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Boston Children's Hospital
Atypical Hemolytic Uremic Syndrome (aHUS)
Study of Ravulizumab in Children and Adolescents With Atypical Hemolytic Uremic Syndrome (aHUS)
The purpose of the study is to assess the efficacy of ravulizumab to control disease activity in children and adolescents with aHUS who have not previously used a complement inhibitor (complement inhibitor treatment-naïve), as…
- Trial name
- NCT03131219
- Testing
- Ravulizumab
- Where
- 18 sites in United States, Belgium and 5 more
- Volunteers
- 34 people
- Sponsor
- Alexion Pharmaceuticals, Inc.
Contraception Behavior, Sexual Behavior
Evaluating the Impact of CHOICE-AYA on Contraceptive Use, Continuation and Satisfaction
This is a prospective study involving two phases: 1) adaptation and 2) intervention, in adolescents aged 14-21 experiencing homelessness.
- Conditions
- Contraception Behavior, Sexual Behavior, Reproductive Behavior
- Trial name
- CHOICE-AYA (NCT05022134)
- Testing
- CHOICE-AYA
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Children's Mercy Hospital Kansas City
Adolescent Pregnancy, Breastfeeding
Breastfeeding Self-Efficacy Theory-Based Education and Counseling in Pregnant Adolescents
Adolescence is the period between the ages of 10 and 19, during which individuals undergo physiological, biological, psychological, and social development, transitioning from childhood to adulthood.
- Conditions
- Adolescent Pregnancy, Breastfeeding, Self-Efficacy
- Trial name
- NCT07025265
- Testing
- reastfeeding Self-Efficacy Theory-Based Antenatal Education and Postpartum Follow-Up Counseling
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Saglik Bilimleri Universitesi
Gestational Weight Gain, Diet, Food, and Nutrition
Nutri-CAP: Nutrition for Children, Adolescent Girls, and Pregnant Women in Slums of Dhaka City
The objective of the research project is to establish an evidence-based sustainable nutrition service delivery platform for optimizing pregnancy weight gain, increasing dietary diversity of adolescent girls, and ensuring proper…
- Conditions
- Gestational Weight Gain, Diet, Food, and Nutrition, Undernutrition, Health Behavior
- Trial name
- NCT05311436
- Testing
- Experimental - Intensive nutrition counselling for pregnant, adolescent and under2 children
- Where
- Bangladesh
- Volunteers
- 3,278 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Polycystic Ovary Disease
"KETOGENIC MEDITERRANEAN VERSUS HYPOCALORIC BALANCED DIET ON POLYCYSTIC OVARIAN ADOLESCENTS"
study was designed to determine the effect of ketogenic Mediterranean diet versus hypocaloric balanced diet on adolescent female with polycystic ovary disease.
- Trial name
- keto- MEDITERR (NCT06610812)
- Testing
- KETOGENIC MEDITERRANEAN diet, hypo-caloric diet:, moderate aerobic exercises
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- MTI University
Pelvic Inflammatory Disease
Improving Primary Care Follow-up for Patients With Pelvic Inflammatory Disease
The investigators hypothesize that text message reminders to girls diagnosed with pelvic inflammatory disease (PID) in the emergency department (ED) will improve follow-up to their primary care provider (PCP) after being…
- Trial name
- NCT01299259
- Testing
- Text Message Reminders
- Where
- United States
- Volunteers
- 95 people
- Sponsor
- Children's Hospital of Philadelphia
Fetal Alcohol Spectrum Disorders, Behavior Problem
Psychoeducation of Parents to Children With FASD
By longitudinal, prospective research in children and adolescents with Fetal Alcohol Spectrum Disorders (FASD) and their parents to explore the beneficial effects of participating in a standardized intervention program in order…
- Conditions
- Fetal Alcohol Spectrum Disorders, Behavior Problem, Adaptive Behavior, Learning Disorders
- Trial name
- NorFASDPEdu (NCT05686473)
- Testing
- Program of psychoeducation of parents and professionals
- Where
- Norway
- Volunteers
- 75 people
- Sponsor
- Sorlandet Hospital HF
Autosomal Dominant Polycystic Kidney Disease (ADPKD)
Safety, Pharmacokinetics, Tolerability and Efficacy of Tolvaptan in Children and Adolescents With ADPKD (Autosomal Dominant Polycystic Kidney Disease)
The primary objective of the study is to assess the long term safety of treatment with tolvaptan in children and adolescents with autosomal dominant polycystic kidney disease (ADPKD).
- Trial name
- NCT02964273
- Testing
- Tolvaptan
- Where
- 20 sites in Belgium, Germany and 2 more
- Volunteers
- 91 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Pregnancy in Adolescence, Adolescent Health
An Evaluation of the Yes You Can... Make Smart Choices Curriculum
The New Jersey Physicians Advisory Group (NJPAG) previously created the Yes You Can…Make Smart Choices! (YYC…MSC!) program with the goal of preventing teen pregnancy and enhancing character development in youth.
- Trial name
- NCT05320666
- Testing
- Yes You Can…Make Smart Choices! (YYC…MSC!) program
- Where
- 13 sites in United States
- Volunteers
- 2,600 people, healthy volunteers welcome
- Sponsor
- New Jersey Physicians Advisory Group
Teen Pregnancy Prevention
Evaluation of Stepping Stones
The goal of this randomized trial is to learn if the Stepping Stones (StSt) intervention has a positive impact on the sexual health and relationship behaviors of sexually active youth between the ages of 12 and 22 years old who…
- Trial name
- StSt (NCT06574217)
- Testing
- Stepping Stones (StSt), Like
- Where
- United States
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- The Policy & Research Group
Chronic Kidney Failure in Children and Young Adults
Phase 3 Clinical Trial With Dapagliflozin in Chronic Kidney Disease in Adolescents and Young Adult Patients
Recent trials have demonstrated positive renal outcomes of sodium-glucose co-transporter-2 inhibitors (SGLT2i) additive to angiotensin-converting-enzyme inhibitors (ACEis) in adult patients with diabetic and non-diabetic chronic…
- Trial name
- DOUBLE_PROTECT (NCT05944016)
- Testing
- Dapagliflozin
- Where
- 16 sites in Germany
- Volunteers
- 102 people
- Sponsor
- University Hospital Goettingen
Polycystic Ovary Syndrome
Impact of Metformin in Teens With Polycystic Ovary Syndrome (PCOS) on Oral Contraceptive Therapy
Oral contraceptives are known to improve menstrual cycles and symptoms in PCOS, however may increase cholesterol. Metformin, a drug to improve insulin resistance, may benefit metabolic state.
- Trial name
- NCT00283816
- Testing
- Metformin, Oral Contraceptive Pill, Lifestyle Management Program
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Teen Pregnancy Prevention
Evaluation of the Making Proud Choices! Teen Pregnancy Prevention Program
Under contract to the Office of Population Affairs (OPA), Mathematica is conducting an impact study of the Making Proud Choices! (MPC) teen pregnancy prevention program.
- Trial name
- NCT04863326
- Testing
- Making Proud Choices, Business as usual
- Volunteers
- 2,810 people
- Sponsor
- Mathematica Policy Research, Inc.
Peer Counseling, LARC Desire
Influence of Peer Mentoring on Adolescent Contraceptive Decision Making
This is a prospective, randomized-controlled trial in which subjects will be randomized to receive either routine contraceptive counseling or peer mentoring plus routine contraceptive counseling.
- Trial name
- ImPACCT (NCT02157285)
- Testing
- Peer Mentor Counseling
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Pregnancy, Sexually Transmitted Infections
Evaluation of the Effectiveness of the POWER Through Choices Program
The purpose of this study is to evaluate the effectiveness of the POWER Through Choices (PTC) curriculum in increasing contraceptive use and delaying sexual initiation among youth living in group foster care homes.
- Trial name
- NCT01565304
- Testing
- POWER Through Choices
- Where
- 3 sites in United States
- Volunteers
- 1,039 people
- Sponsor
- Mathematica Policy Research, Inc.