Clinical trials: Teenager
Hiv, Contraception
Supporting Young Women's Reproductive Health by Harnessing Prosociality Among Drug Shopkeepers
The goal of the study is to operationalize and test the preliminary impact of providing regular customer feedback from adolescent girls and young women (AGYW) to drug shopkeepers on the distribution of contraceptives and HIV…
- Trial name
- NCT05525533
- Testing
- Harnessing prosocial and social image motivations for behavior change
- Where
- 2 sites in Tanzania
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Bulimia Nervosa
Cognitive Behavior Therapy for Adolescents With Bulimia
We are interested in studying two different psychological treatments for eating disorders for adolescents (ages 12-18). The study is designed to help adolescents who are having problems with binge eating and/or purging.
- Trial name
- NCT00974038
- Testing
- psychotherapy
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- New York State Psychiatric Institute
Constitutional Mismatch Repair Deficiency Syndrome, Hematopoietic and Lymphoid Cell Neoplasm
Testing the Combination of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) in Children, Adolescent, and Young Adult Patients With Relapsed/Refractory Cancers That Have an Increased Number of Genetic Changes, The 3CI Study
This phase Ib trial investigates the side effects of the combination of nivolumab and ipilimumab, and to see how well they work in treating patients with cancers that have come back (relapsed) or does not respond to treatment…
- Conditions
- Constitutional Mismatch Repair Deficiency Syndrome, Hematopoietic and Lymphoid Cell Neoplasm, Lynch Syndrome, Recurrent Lymphoma
- Trial name
- NCT04500548
- Testing
- Biospecimen Collection, Ipilimumab, Nivolumab
- Where
- 9 sites in United States, Canada
- Sponsor
- National Cancer Institute (NCI)
Microbial Colonization
Vaginal Microbiota, and STI/HIV Risk Among Adolescent Girls and Young Women
The investigators are doing a study on the bacteria that normally live in the vagina and what effect, if any, Depo-Provera has on the bacteria.
- Trial name
- AIMS (NCT03196492)
- Testing
- No intervention
- Where
- United States
- Volunteers
- 234 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Emotion Regulation, Parent-Child Relations
Improving Emotional Regulation Skills of Children in Difficulty in Shenzhen
The study aims to 1) improve the emotional regulation strategies of children in difficulty in Shenzhen, and 2) develop and publish a set of evidence-based intervention manuals for professional use.
- Conditions
- Emotion Regulation, Parent-Child Relations, Happiness, Positive Affect
- Trial name
- NCT06331936
- Testing
- Emotion regulation
- Where
- China
- Volunteers
- 183 people, healthy volunteers welcome
- Sponsor
- City University of Hong Kong
Lymphoepithelioma-like Carcinoma, Lymphoepithelioma
Safety and Efficacy of Pucotenlimab in pLECC
Lymphoepithelioma-like carcinoma (LELC) in children is a rare epithelial malignant tumor. Regarding pediatric lymphoepithelioma-like carcinoma (pLELC), its clinicopathological features, prognosis, and molecular characteristics…
- Conditions
- Lymphoepithelioma-like Carcinoma, Lymphoepithelioma, Carcinoma
- Trial name
- NCT06969534
- Testing
- Pucotenlimab combined with GP regimen
- Where
- China
- Volunteers
- 33 people
- Sponsor
- Sun Yat-sen University
Diabetes Mellitus, Type 1
ECG Changes in Children and Adolescents With Type 1 Diabetes
Diabetes Mellitus type 1 is characterized by an absolute insulin deficiency caused by T-cell-mediated autoimmune destruction of pancreatic β-cells .
- Trial name
- NCT03260998
- Testing
- electrocardiogram
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Assiut University
ADHD
Safety and Efficacy of SPD489 in Adolescent Subjects Aged 13-17 Years With Attention-Deficit/Hyperactivity Disorder (ADHD)
The primary objective of the study is to evaluate the efficacy of SPD489 compared to placebo in adolescent subjects (13-17 years of age inclusive) with ADHD in the analog classroom setting based on the Permanent Product Measure…
- Trial name
- NCT01274221
- Testing
- SPD489
- Where
- 6 sites in United States
- Sponsor
- Shire
Diabetes
Adolescent Fitness Assessment Program
The purpose of this study is to implement a peer modeling intervention to improve self-efficacy and aerobic fitness in obese youth.
- Trial name
- AFAP (NCT01382121)
- Testing
- Peer Modeling, Control
- Where
- Canada
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University of Western Ontario, Canada
Mental Health Issues
Mindmatters: Tutoring and Counseling Program
The tutoring and counseling program for adolescents from low socioeconomic backgrounds facing mental health challenges during the COVID-19 pandemic will be assessed using a randomized controlled trial.
- Trial name
- NCT07007871
- Testing
- Tutoring and Counselling (1), Tutoring and Counselling (2)
- Where
- Hong Kong
- Volunteers
- 170 people
- Sponsor
- Education University of Hong Kong
Idiopathic Adolescent Scoliosis, Scoliosis Idiopathic
Effects of Core Stabilization Exercises and Rotation Angular Breathing Exercises Among Idiopathic Scoliosis Patients
This study is a single-blind, two-arm parallel-group randomized controlled trial designed to evaluate the effects of core stabilization exercises combined with rotational angular breathing exercises on adolescents with idiopathic…
- Trial name
- CSE RAB IS (NCT07601893)
- Testing
- Core Stabilization Exercises, Standard Care (in control arm)
- Where
- 2 sites in Pakistan
- Volunteers
- 32 people
- Sponsor
- Lahore University of Biological and Applied Sciences
Anorexia Nervosa, Eating Disorder
Severe Anorexia Nervosa Personal Recovery
A growing qualitative literature about personal recovery process in mental disorders emerges. However in Anorexia Nervosa (AN), it remains few understood, especially in severe AN during adolescence.
- Trial name
- ANAPR (NCT03712384)
- Testing
- Semi structured face to face interview
- Where
- France
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Institut Mutualiste Montsouris
Substance Abuse, Families
Family-Based Drug Services for Young Disaster Victims
This protocol seizes this rare scientific opportunity to test an integrative family based model to address youths' coexisting substance abuse and trauma in the wake of Hurricane Katrina.
- Conditions
- Substance Abuse, Families, Trauma
- Trial name
- Katrina (NCT01859000)
- Testing
- Multidimensional Family Therapy, Group CBT
- Where
- 2 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Miami
Myopia, Visual Fatigue
Impact of Various Myopia Management Strategies on Asthenopia Among Pediatric and Adolescent Populations
Different myopia control interventions have certain effects on ocular asthenopia in children and adolescents. As children and adolescents are in a critical period of visual development, the presence of asthenopia may lead to an…
- Trial name
- NCT07691671
- Volunteers
- 600 people
- Sponsor
- Tianjin Medical University Eye Hospital
Acute Lymphobkastic Leukemia, Medication Adherence
The AYA Oncology Self-care Movement
This trial will test the impact of a social media intervention for improving oral chemotherapy adherence among adolescents and young adults (AYAs) with acute lymphoblastic leukemia.
- Trial name
- #AYAOSM (NCT07724652)
- Testing
- Educational Website, #AYAOSM
- Where
- 4 sites in United States
- Volunteers
- 200 people
- Sponsor
- Northwestern University
Anxiety Disorders and Symptoms, Depressive Symptoms
Indicated Prevention Transdiagnostic Intervention for Adolescents At High Risk of Emotional Problems
Emotional disorders (anxiety and/or depression) are severely undiagnosed and untreated despite being among the most common mental disorders, particularly at a young age.
- Trial name
- PROCARE-I (NCT05252026)
- Testing
- PROCARE-I (UP-A for indicated purposes), Active control condition
- Where
- 3 sites in Spain
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- University of Jaén
Type 1 Diabetes, Motivational Interviewing
The Impact of Motivational Interviews Conducted Through Tele-Nursing on Diabetes Management
The deterioration of glycemic control in adolescents with Type 1 diabetes (T1DM) is a genuine cause for concern. Possible reasons for worsening glycemic control in youth include lack of monitoring, inadequate self-care…
- Trial name
- NCT06208618
- Testing
- Education and Motivational Interviews
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people
- Sponsor
- Eskisehir Osmangazi University
Diffuse Intrinsic Pontine Glioma
Biological Medicine for Diffuse Intrinsic Pontine Glioma (DIPG) Eradication
Diffuse Intrinsic Pontine Gliomas (DIPG) appear almost exclusively in children and adolescents, representing 15 to 20% of posterior fossa tumours.
- Trial name
- BIOMEDE (NCT02233049)
- Testing
- Erlotinib, Everolimus, Dasatinib
- Where
- France
- Volunteers
- 250 people
- Sponsor
- Gustave Roussy, Cancer Campus, Grand Paris
Trauma, Anxiety
The Ukrainian Student Problem Solving Project
The purpose of this study is to test the effectiveness of a universal, digital, single-session intervention for youth mental health, functioning, and well-being.
- Conditions
- Trauma, Anxiety, Depression, Child Behavior
- Trial name
- NCT06064578
- Testing
- Project SOLVE
- Where
- United States
- Volunteers
- 778 people, healthy volunteers welcome
- Sponsor
- Harvard University
Spina Bifida, Cerebral Palsy
Assessing Transition Practices for Children With Disabilities: Pathways to a Successful Adulthood
Transition to adult care is a purposeful and structured movement of youth with complex disabilities from child centered to adult oriented services. This complex and potentially challenging period requires careful planning.
- Conditions
- Spina Bifida, Cerebral Palsy, Spinal Cord Injury, Spastic Paraplegia
- Trial name
- NCT07706517
- Testing
- Chart review, Semi-structured interview
- Where
- France
- Volunteers
- 128 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne