Clinical trials: Teenagers
Lymphoma
Combination Chemotherapy Followed By Stem Cell Transplant in Treating Young Patients With Progressive or Relapsed Anaplastic Large Cell Lymphoma
RATIONALE: Giving combination chemotherapy and total-body irradiation before a peripheral stem cell transplant that uses the patient's or a donor's stem cells, helps stop both the growth of cancer cells and the patient's immune…
- Trial name
- NCT00317408
- Testing
- anti-thymocyte globulin, busulfan, carboplatin
- Where
- 98 sites in Austria, Belgium and 10 more
- Volunteers
- 96 people
- Sponsor
- European Inter-group Cooperation on Childhood and Adolescent Non Hodgkin Lymphoma
Uncomplicated Urinary Tract Infections
A Study to Investigate Pivmecillinam Versus Nitrofurantoin in Female Adolescents 12 to Less Than 18 Years of Age With Uncomplicated Urinary Tract Infection
Multicenter, Randomized, Open-label, Active-controlled Study with Blinded Assessor to Evaluate the Safety and Tolerability of Pivmecillinam Hydrochloride versus Nitrofurantoin for the Treatment of Female Pediatric Subjects, 12…
- Trial name
- NCT07871968
- Testing
- Pivya (Pivmecillinam 185 mg), Nitrofurantoin 100 mg (nitrofurantoin monohydrate/macrocrystalline capsule)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Alembic Therapeutics
Pain, Injection Site Reaction
Safety of Pediatric COVID-19 Vaccination
This is a prospective, observational study. During the study, children and adolescents (ages ≥ 5 to < 16) will be followed post administration of mRNA COVID-19 vaccines.
- Conditions
- Pain, Injection Site Reaction, Adverse Drug Event
- Trial name
- NCT05157191
- Testing
- Observational
- Where
- 5 sites in United States
- Volunteers
- 299 people, healthy volunteers welcome
- Sponsor
- Duke University
Inflammation, Psychosocial Functioning
Mindfulness Meditation Neuroimaging Study for Undergraduates
This study is designed to test the effectiveness of mindfulness meditation intervention classes on psychosocial health outcomes.
- Conditions
- Inflammation, Psychosocial Functioning, Depression, Anxiety
- Trial name
- NCT05304052
- Testing
- Mindfulness Meditation classes
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Chronic Constipation With Overflow, Encopresis With Constipation and Overflow Incontinence
Sacral Neuromodulation in Children and Adolescents
The purpose of this study is to assess the efficacy of neuromodulation for treatment of chronic constipation and fecal incontinence in pediatric patients and to evaluate the differences between the invasive vs.
- Conditions
- Chronic Constipation With Overflow, Encopresis With Constipation and Overflow Incontinence, Hirschsprung's Disease, Anorectal Malformations
- Trial name
- NCT04713085
- Testing
- Invasive Sacral Neuromodulation, Non-invasive Sacral Neuromodulation
- Where
- Germany
- Volunteers
- 48 people
- Sponsor
- Friedrich-Alexander-Universität Erlangen-Nürnberg
Healthy
Influence of Parents and Friends on Children and Adolescents
The objective of this study is to directly compare the effects of parents and friends on overweight and non-overweight children and adolescents' food intake and food selection using a cross-sectional design.
- Trial name
- NCT00875576
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University at Buffalo
Dyslexia
VAlidation of an Educational Technological Tool for Dyslexic Adolescents: an Open Controlled Study
Virtual reality (VR) and augmented reality (AR) are gaining importance in the rehabilitation programs for learning disabilities.
- Trial name
- FORDYS (NCT05028647)
- Testing
- Virtual reality training, Augmented reality training
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- IRCCS Eugenio Medea
Soft Tissue Sarcoma of the Lower Extremity, Bone Tumor of the Lower Extremity
Prehabilitation in Childhood Soft Tissue or Bone Sarcomas
This study aims to investigate the feasibility of a prehabilitative training intervention. The intervention includes specific strength and balance exercises during neoadjuvant chemotherapy with children and adolescents diagnosed…
- Conditions
- Soft Tissue Sarcoma of the Lower Extremity, Bone Tumor of the Lower Extremity, Childhood and Adolescent Cancer
- Trial name
- Prehab4Kids (NCT06743958)
- Testing
- Exercise intervention
- Where
- 2 sites in Germany
- Volunteers
- 16 people
- Sponsor
- Technical University of Munich
Diabetes Mellitus, Eye Diseases
Shanghai Children and Adolescent Diabetes Eye Study
To compare the prevalence of eye disease between children and adolescents with diabetes mellitus and healthy people, and to analyze the related factors of eye diseases in diabetic patients.
- Trial name
- SCADE (NCT03587948)
- Testing
- Diabetes mellitus
- Where
- China
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Adolescence Obesity
Phase Ib Study of Efsubaglutide Alfa Injection in Obese Adolescents
This is a Phase Ib, randomized, double-blind, placebo-controlled clinical study to evaluate the safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) of Efsubaglutide Alfa Injection following multiple-dose…
- Trial name
- NCT07693426
- Testing
- Efsubaglutide Alfa 5 mg QW, Efsubaglutide Alfa 10 mg QW, Efsubaglutide Alfa 20 mg QW
- Where
- 5 sites in China
- Volunteers
- 36 people
- Sponsor
- Shanghai Yinnuo Pharmaceutical Technology Co., Ltd.
Tabagism
Prevention in a Virtual Community Game
The main objective of the SCOTT project is to reduce tobacco experimentation of teenagers through an online intervention based on social networking and empowerment of users. Specific objectives of this emerging project are : 1.
- Trial name
- SCOTT (NCT04888208)
- Testing
- Behavioral
- Where
- France
- Volunteers
- 106 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Adult Acute Lymphocytic Leukemia
German Multicenter Trial for Treatment of Newly Diagnosed Acute Lymphoblastic Leukemia in Adults (07/2003)
The study evaluates the efficacy and tolerability of an intensified induction and consolidation therapy. Thereafter patients receive individualised treatment stratified according to relapse risk with stem cell transplantation for…
- Trial name
- NCT00198991
- Testing
- Cyclophosphamide, Dexamethasone, Vincristine
- Where
- Germany
- Volunteers
- 1,883 people
- Sponsor
- Goethe University
Meningitis, Meningococcal Meningitis
Immunogenicity and Safety of an Investigational Quadrivalent Meningococcal Conjugate Vaccine in Healthy Adolescents
The purpose of the study was to evaluate the immunogenicity and describe the safety of Meningococcal Polysaccharide (Serogroups A, C, Y and W) Tetanus Toxoid (MenACYW) Conjugate vaccine compared to the licensed vaccine MENVEO® in…
- Conditions
- Meningitis, Meningococcal Meningitis, Meningococcal Infections
- Trial name
- NCT02199691
- Testing
- Meningococcal Polysaccharide (Serogroups A, C, Y, and W135) Tetanus Toxoid Conjugate Vaccine, Meningococcal (Groups A, C, Y and W135) Oligosaccharide Diphtheria CRM197 Conjugate Vaccine, Adacel®: Tetanus Toxoid, Reduced Diphtheria Toxoid and Acellular Pertussis Vaccine Adsorbed
- Where
- 36 sites in United States, Puerto Rico
- Volunteers
- 1,715 people, healthy volunteers welcome
- Sponsor
- Sanofi Pasteur, a Sanofi Company
Mental Health Wellness 1
Mindfulness-based Stress Reduction for Pediatric Mental Health
Mindfulness-based stress reduction (MBSR) is a group program in which participants are taught to be mindful or present-focused. MBSR programs consist of instruction in a variety of mindfulness meditations including body scan…
- Trial name
- MBSR (NCT01307943)
- Testing
- Mindfulness-based stress reduction program, Usual care
- Where
- Canada
- Volunteers
- 85 people
- Sponsor
- University of Alberta
Cytomegalovirus Infections, Primary Immune Deficiency Disorder
Virus Specific Cytotoxic T-Lymphocytes (CTLs) for Refractory Cytomegalovirus (CMV)
CMV cytotoxic T cells (CTLs) manufactured with the Miltenyi CliniMACS Prodigy Cytokine Capture System will be administered in children, adolescents and young adults (CAYA) with refractory cytomegalovirus (CMV) infection post…
- Trial name
- NCT03266640
- Testing
- viral specific cytotoxic t-lymphocytes
- Where
- 9 sites in United States
- Volunteers
- 20 people
- Sponsor
- New York Medical College
Attention Deficit Hyperactivity Disorder, Executive Dysfunction
Executive Control Training for Adolescents With ADHD: A Randomized Controlled Effectiveness Trial
The goal of this clinical trial is to evaluate an evidence-based, non-pharmacological treatment alternative: Goal Management Training (GMT) for adolescents with Attention-Deficit/Hyperactivity Disorder (ADHD).
- Trial name
- ADHD Effect (NCT05874791)
- Testing
- Goal Management training
- Where
- 2 sites in Norway
- Volunteers
- 120 people
- Sponsor
- Sykehuset Innlandet HF
E-Cig Use
Respiratory Effects of E-Cigarettes in Obese Youth
To determine vaping behaviors and respiratory function in obese and nonobese youth e-cigarette users.
- Trial name
- RESEC (NCT05869318)
- Testing
- ECIG own, ECIG Vuse
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
AYA Cancer Patients, AYA Cancer Survivors
the Challenges of Young Adults With Cancer
The study aims to describe unmet needs of Adolescent \&amp; Young Adults (AYA) with gastrointestinal and breast cancers in relation to: a) quality of life, b) education, c) finances and Insurance, and d) childbearing and…
- Trial name
- AYANDRA (NCT06594510)
- Where
- Italy
- Volunteers
- 580 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Chronic Health Condition
Apply the (MyTransition) App In Transition
Moving from child care to adult care is a hard time for patients and their families. Parents of children with chronic conditions say they need more support around the time of changing care.
- Trial name
- ApplyIT (NCT03188224)
- Testing
- MyTransition app
- Where
- Canada
- Volunteers
- 39 people
- Sponsor
- McMaster University
Mental Disorder in Adolescence
Personalized Assessment of Client Experiences
The purpose of this study is to compare two clinical approaches to youth mental health care.
- Trial name
- PACE (NCT04369924)
- Testing
- Unidimensional Measurement-Based Care, Multidimensional Measurement-Based Care
- Where
- United States
- Volunteers
- 1,261 people
- Sponsor
- University of Miami
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