Clinical trials: Teeth Sensitivity
Dental Caries
Intra Oral Appliance (IOA) Model Evaluating the Efficacy of Sensitive Toothpaste
This single-center, randomized, double-blind, three-period crossover in situ study evaluated the enamel remineralization potential and fluoride bioavailability of three dentifrices: a fluoride-free negative control, a positive…
- Trial name
- NCT07419763
- Testing
- Negative Control Toothpaste, Active Comparator, Test toothpaste
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Church & Dwight Company, Inc.
Dentin Sensitivity, Xerostomia
Effect of a Self-adhering Material in Dental Hypersensitivity
Aim: To compare the desensitizing capacity of Vertise Flow™ (VF), a new self adhering material, in the treatment of dentine hypersensitivity (DH) in patients who are xerostomic due to radiotherapy for head and neck cancer.
- Trial name
- NCT02766127
- Testing
- Veritise Flow, Universal Dentin Sealant, Clearfil Protect Bond
- Where
- Italy
- Volunteers
- 17 people
- Sponsor
- Università degli Studi di Sassari
Dentin Sensitivity
A Pilot Clinical Study to Evaluate the Safety and Efficacy of Marketed Oxalate Strips Compared to a Marketed Safety Pen
This pilot study will evaluate the safety and effectiveness of a marketed sensitivity strip on existing dentinal hypersensitivity compared to a marketed sensitivity pen.
- Trial name
- NCT02384044
- Testing
- Crest® Sensi-Stop™ Strips, Colgate® Sensitivity Relief Pen
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Procter and Gamble
Dentin Sensitivity
Effect of an Experimental Cannabidiol Gel on Tooth Sensitivity
The goal of this clinical trial will be to evaluate the effect applying an experimental gel based on cannabidiol oil (CBD) on tooth sensitivity induced by tooth bleaching with 35% hydrogen peroxide (HP).
- Trial name
- NCT07027566
- Testing
- Potassium nitrate and sodium fluoride, Cannabidiol (CBD) Gel, Natrosol 4% Gel
- Where
- Brazil
- Volunteers
- 75 people
- Sponsor
- Universidade Federal do Para
Dentine Hypersensitivity
Investigating the Efficacy of a Dentifrice in Providing Long Term Relief From Dentinal Hypersensitivity
Clinical studies have demonstrated long term relief from dentine hypersensitivity with twice daily brushing of a toothpaste containing stannous fluoride in comparison to marketed (negative) controls.
- Trial name
- NCT01827670
- Testing
- Stannous fluoride, Sodium monofluorophosphate
- Where
- United States
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Dentin Sensitivity, Molar Incisor Hypomineralization
Control of Pain Due to Dentin Hypersensitivity in Individuals With Molar-incisor Hypomineralization
Background: Dentin hypersensitivity (DH) is defined as high sensitivity of the vital dentin when exposed to thermal, chemical or tactile stimuli.
- Trial name
- NCT04407702
- Testing
- Hygiene Instructions, Sealant application, Low-level Laser
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Dentin Sensitivity
Effects of an Oxalate Containing Product on Dentinal Hypersensitivity With Dental Prophylaxis
This study will assess sensitivity during a dental prophylaxis with or without the use of a potassium oxalate salt solution.
- Trial name
- NCT02481557
- Testing
- Oxalate Salt Solution
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Procter and Gamble
Tooth Sensitivity
Different Concentrations of Potassium Nitrate in In-office Tooth Bleaching Sensitivity
The aim of this randomized, double-blind controlled clinical study was to evaluate the absolute risk and intensity of sensitivity to dental bleaching in adults on the application of two different gels based on potassium nitrate…
- Trial name
- NCT03323372
- Testing
- 3% potassium nitrate and 0.25% sodium fluoride, 5% potassium nitrate and 2% sodium fluoride
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Amazonas
Dentin Hypersensitivity
A Study to Evaluate the Efficacy and Safety of KH001 in Patients with Dentin Hypersensitivity
The purpose of this study is to evaluate the efficacy and safety of KH001 in patients with dentin hypersensitivity.
- Trial name
- NCT06264453
- Testing
- KH001
- Where
- South Korea
- Volunteers
- 171 people
- Sponsor
- HysensBio Co., Ltd
Dentine Hypersensitivity
The Efficacy of a Dentifrice in Providing Relief From the Pain of Dentinal Hypersensitivity
A study to compare the efficacy of a test dentifrice against a control dentifrice in reducing dentinal hypersensitivity over an eight week treatment period.
- Trial name
- NCT01592864
- Testing
- Stannous Fluoride, Sodium Monofluorophosphate
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Dentinal Sensitivity, Dentinal Hypersensitivity
Comparative Efficacy of Different Dentin Occluding Toothpaste Technologies
The purpose of this clinical study is to evaluate and compare how well three different types of toothpaste technologies work to relieve tooth sensitivity, also known as dentin hypersensitivity.
- Trial name
- SENSBZ (NCT07664592)
- Testing
- 8% arginine + Zinc toothpaste, 5% Calcium Sodium Phosphosilicate toothpaste, 8% arginine toothpaste
- Where
- Brazil
- Volunteers
- 132 people
- Sponsor
- Colgate Palmolive
Hypersensitivity Dentin
Pain Control in Dentin Hypersensitivity in Patients With MIH
This study aims to evaluate the effectiveness of different protocols in controlling dentin hypersensitivity in patients with teeth affected by MIH.
- Trial name
- NCT04268238
- Testing
- Hygiene Guidance, Sealant Application, Low Level Laser Application
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Dentin Sensitivity
Study Investigating Efficacy of an Occluding Dentifrice for Dentine Hypersensitivity
This study will investigate the efficacy of an experimental dentifrice containing 0.454% weight/weight (w/w) stannous fluoride in relieving dentine hypersensitivity (DH) after twice daily brushing, over a 2 week treatment period…
- Trial name
- NCT02705716
- Testing
- 0.454% w/w stannous fluoride (1100ppm fluoride), 0.76% sodium monofluorophosphate (1000ppm fluoride)
- Where
- 3 sites in United Kingdom
- Volunteers
- 409 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Sensitivity, Tooth
Dentinal Hypersensitivity Reduction Efficacy Study
Assess the clinical efficacy of CSPR Toothpaste containing 8% arginine to provide dentinal hypersensitivity relief
- Trial name
- NCT06960148
- Testing
- CSPR Toothpaste, Colgate Dental Cream Toothpaste
- Where
- China
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Photobiomodulation, Dental Hypersensitivity
Evaluation of Tooth Sensitivity After Scaling and Root Planing Treated With Photobiomodulation
One hundred twenty patients with dentin sensibility after non-surgical scaling and root planning (SRP) will be randomly included in 2 groups: Experimental Group: SRP+ Photobiomodulation (PBM) (660nm, 100W, area 0,5cm2, 200w/cm2…
- Trial name
- NCT05946265
- Testing
- Photobiomodulation, simulation of Photobiomodulation
- Where
- Brazil
- Volunteers
- 112 people
- Sponsor
- University of Nove de Julho
Dental Restoration Failure of Marginal Integrity
Different Application Strategies When Using Futurabond Universal in Class V Cavities
Treatment clinical trial, randomized, controled, parallel, double-blinded, with four groups, that aims to evaluate the best application strategy when using a new Universal Adhesive system, Futurabond Universal (VOCO GmbH…
- Trial name
- FUUC (NCT03244124)
- Testing
- Self-Etching Application Strategy, Enamel Etching Application Strategy, Etch&Rinse Dry Application Strategy
- Where
- 2 sites in Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universidade Federal Fluminense
Dentine Hypersensitivity, Tooth Erosion
The Effects of Mouthguard and Desensitizing Toothpaste in Reducing Dental Hypersensitivity
Tooth hypersensitivity due to dental erosion is one of the most common problem related to swimming in improper pH chlorinated pools.
- Trial name
- NCT03515902
- Testing
- mouthguard, mouthguard with desensitizing toothpaste
- Where
- Thailand
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Khon Kaen University
Dentin Sensitivity
Clinical Trial to Compare the Efficacy of a Fluoride Gel and a Dental Bonding Agent in Treatment of Tooth Sensitivity
This study compares the efficacy of two dental interventions in the treatment of cervical dentine sensitivity. The participants will be selected from adult dental patients registered at a general dental practice in West Sussex…
- Trial name
- NCT02919202
- Testing
- Colgate Fluoride Varnish Suspension. 2.26% Sodium Fluoride., Self-etching Dentine Bonding Agent
- Where
- United Kingdom
- Volunteers
- 26 people
- Sponsor
- University of Kent
Caries, Dental, Tooth Decay
Efficacy of Solventum™ Vitrebond™ Pulp Protect Liner/Base Used as a Liner/Base Under Dental Restorations
This is a clinical study evaluating a new dental product called Solventum™ Vitrebond™ Pulp Protect Liner/Base. This new product is designed to be used as a liner or base between the tooth and the dental filling, as well as for a…
- Conditions
- Caries, Dental, Tooth Decay, Dental Decay, Tooth Sensitivity
- Trial name
- NCT07261137
- Testing
- Vitrebond™ Pulp Protect Liner/Base, Vitrebond™ Plus (comparator)
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Solventum US LLC
Dentine Hypersensitivity
Clinical Efficacy of a Toothpaste in Providing Relief From the Pain of Dentinal Hypersensitivity
A study to compare the efficacy of a test dentifrice against a control dentifrice in reducing dentinal hypersensitivity over a two week treatment period.
- Trial name
- NCT01592851
- Testing
- Stannous Fluoride, Sodium Monofluorophosphate
- Where
- United States
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline