Clinical trials: Teeth Sensitivity
Traumatic Brain Injury
The Biomarkers in the Hyperbaric Oxygen Brain Injury Treatment Trial (BioHOBIT)
There are no therapeutic agents that have been shown to improve outcomes from severe traumatic brain injury (TBI). Critical barriers to progress in developing treatments for severe TBI are the lack of: 1) monitoring biomarkers…
- Trial name
- NCT04855396
- Where
- 11 sites in United States, Canada
- Volunteers
- 150 people
- Sponsor
- University of Michigan
Dentin Hypersensitivity
Effect of Using Different Varnishes on Dentin Hypersensitivity; Na Fluoride and Nano-silver Fluoride
2 different varnishes will be used to test their effectiveness in controlling teeth hypersensitivity in adult patient.
- Trial name
- NCT04731766
- Testing
- Citrine 5 % sodium fluoride, concocted nano-silver fluoride
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Nayera Hassanien Mohamed
Dentin Sensitivity, Tooth Bleaching
Evaluation of Sensitivity With and Without Sonic Activation of a Desensitizing Gel Before in Office Bleaching in Adults
This randomized, controlled clinical trial, triple-blind, split-mouth type was conducted aiming to assess the absolute risk of sensitivity with and without sonic activation of a desensitizing gel previously to the in-office…
- Trial name
- NCT03039270
- Testing
- With sonic activation (SMART Device®), Control (Without sonic activation)
- Where
- Brazil
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Federal University of Amazonas
Carious Dentin
Postoperative Hypersensitivity and Digital Radiographic Assessment of a Zinc Modified Versus a Conventional Glass Ionomer Cement in Deep Carious Lesion: Randomized Controlled Clinical Trial
The study aim to evaluate the difference between the effect of zinc modified glass ionomer and conventional glass ionomer on the success of partial caries removel technique
- Trial name
- NCT03285022
- Testing
- Partial caries removel techniques
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Cairo University
Vitamin D Deficiency, Obesity
D-tecting Disease - From Exposure to Vitamin D During Critical Periods of Life
Vitamin D deficiency is common among otherwise healthy pregnant women and may have consequences for them as well as the early development and long-term health of their children.
- Conditions
- Vitamin D Deficiency, Obesity, Diabetes Mellitus, Pre-Eclampsia
- Trial name
- D-tect (NCT03330301)
- Testing
- D-tect
- Where
- Denmark
- Volunteers
- 222,776 people
- Sponsor
- Bispebjerg Hospital
Dentin Sensitivity
Exploratory Clinical Study to Investigate the Ability of an Experimental Combination Dentifrice to Protect Sensitive Teeth
This proof of principle (PoP) study will evaluate the ability of an experimental combination toothpaste formulation to protect sensitive teeth from dentine hypersensitivity.
- Trial name
- NCT05243745
- Testing
- 3% PVM/MA + 5% KNO3 Combination, 3% PVM/MA only, 5% KNO3 Only
- Where
- United Kingdom
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- HALEON
Dental Hypersensitivity
Dentin Hypersensitivity Reduction Efficacy Clinical
The objective of this study is to assess clinical efficacy of a toothpaste containing stannous fluoride (Colgate-Palmolive Company, New York, NY, USA) to provide dental hypersensitivity relief (tactile and air blast) in…
- Trial name
- NCT07738198
- Testing
- 0.454% stannous fluoride toothpaste, 5% potassium nitrate, 0.76% sodium monofluorophosphate
- Where
- United States
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Dentin Sensitivity
A Study to Assess Efficacy of an Experimental Oral Rinse in Providing Long Term Relief From Dentinal Hypersensitivity
To investigate the efficacy of an experimental oral rinse, containing 1.5% potassium oxalate (KOX) and 0 parts per million (ppm) fluoride in relieving dentine hypersensitivity (DH) after 8 weeks use compared with a placebo oral…
- Trial name
- NCT03238352
- Testing
- Potassium oxalate, Sodium fluoride
- Where
- United States
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Dentine Hypersensitivity
Meta-analysis of Stannous Fluoride Dentifrice and the Effects on Dentine Hypersensitivity
The aim of this 11 study analysis was to compare the effect of bioavailable stannous fluoride (SnF2) on dentine hypersensitivity versus a positive or negative control dentifrice.
- Trial name
- NCT04005417
- Testing
- Stannous fluoride dentifrice, Positive control dentifrice, Negative control dentifrice
- Where
- United States
- Volunteers
- 1,036 people, healthy volunteers welcome
- Sponsor
- Procter and Gamble
Dentin Hypersensitivity, Dentin Desensitizing Agents
Clinical Evaluation of Efficacy of Shield Force Plus Varnish VS Sodium Fluoride on Dentin Hypersensitivity
The aim of the study to compare the clinical effectiveness of Shield Force Plus (SFP) versus sodium fluoride varnish in the management of hypersensitivity of cervical dentin in adult patients for 8weeks.
- Trial name
- NCT04484844
- Testing
- TOKUYAMA SHIELD FORCE PLUS, Sodium Fluoride 5% Dental Varnish
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Cairo University
Class II Dental Caries, Sensitivity, Tooth
Post-operative Sensitivity in Composite Restorations
Participants will be divided into groups. In group A, Composite restoration done using oblique incremental technique. In group B, Bulk-fill technique was used.
- Trial name
- NCT06092567
- Testing
- Group A ( Oblique Incremental Placement Technique), Group B (Bulk-fill Placement technique)
- Where
- Pakistan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Pakistan Institute of Medical Sciences
Dentin Sensitivity
The Efficacy of an Occluding Dentifrice in Providing Relief From Dentinal Hypersensitivity (DH)
This single center study will investigate the efficacy of an experimental stannous fluoride containing dentifrice in relieving DH compared with a standard fluoride dentifrice after short term use.
- Trial name
- NCT02924350
- Testing
- Stannous fluoride, Sodium monofluorophosphate
- Where
- United Kingdom
- Volunteers
- 205 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Dentin Hypersensitivity
The Influence of Desensitizing Agent on Postoperative Sensitivity in Posterior Composite Restoration
This study aims to investigate the influence of desensitizing agents on reducing post-operative sensitivity in posterior composite.
- Trial name
- NCT06113874
- Testing
- Hurriseal desensitizer, Gluma desensitizer
- Where
- Egypt
- Volunteers
- 10 people
- Sponsor
- Nourhan M.Aly
Sensitivity, Tooth
Efficacy of a Desensitizing Agent During At-home Bleaching
The main objective of this study is to evaluate if the use of UltraEZ during at-home bleaching treatment is effective in reducing tooth sensitivity, as well as doesn't affect the degree of tooth bleaching.
- Trial name
- NCT06371092
- Testing
- UltraEZ
- Where
- Spain
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Santiago de Compostela
Dentin Sensitivity
A Pilot Study to Assess Nominal Versus Controlled Stimuli on Dentinal Hypersensitivity
This pilot study will evaluate the use of nominal stimuli to assess dentinal hypersensitivity response relative to a clinically-controlled stimulus.
- Trial name
- NCT02406573
- Testing
- Crest® Sensi-Stop™ Strips
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Procter and Gamble
Dental Pain, Muscle Sensitivity to Pressure
Analgetic Effect of Nitrousoxide-oxygen Inhalation for Dental Treatment of Children
To assess the analgetic effect of nitrousoxide-oxygen inhalation on pain perception in 12-15 years old children from 1) the dental pulp; 2) the masseter muscle; 3) the skin on the upper lip
- Conditions
- Dental Pain, Muscle Sensitivity to Pressure, Skin Sensitivity to Electric Stimulation
- Trial name
- NCT01022294
- Testing
- Nitrousoxide-oxygen and atmospheric air, Atmospheric air; nitrousoxide-oxygen
- Where
- Denmark
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Dentine Hypersensitivity
A Study to Evaluate the Dentinal Hypersensitivity Efficacy of Two Experimental Mouthwash Formulations
The aim of this study is to evaluate the clinical efficacy of two experimental mouthwash formulations, against a placebo mouthwash (without experimental ingredients).
- Trial name
- NCT07741032
- Testing
- 3% KNO3 Mouthwash, 2% HPC Mouthwash, 0% KNO3 Mouthwash
- Where
- Germany
- Volunteers
- 118 people
- Sponsor
- HALEON
Molar Incisor Hypomineralization
Evaluation of the Effectiveness of Various Desensitizing Treatment Protocols
The objective of this research was to evaluate the clinical success of desensitization treatments using four different materials in the first permanent molars (FPMs) affected by MIH.
- Trial name
- NCT07085689
- Testing
- Sodium Fluoride Varnish (5%), Silver diamine fluoride- potassium iodide, Aqueous Silver Fluoride
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Hacettepe University
Tooth Sensitivity
Evaluation of Sensitivity and Color Change of Different Protocols of In-office Dental Bleaching
Clinical randomized single-blind trial, used to measure the level of tooth sensitivity (TS) after in-office dental bleaching sessions, on volunteers using a modified visual analog scale (VAS).
- Trial name
- NCT07597044
- Testing
- Standard in-office tooth bleaching, Alternative in-office tooth bleaching
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidade Federal Fluminense
Color Changes During Tooth Formation
Effect of an Anti-inflammatory on Tooth Sensitivity Caused by Bleaching
Perhaps the use of a more selective anti-inflammatory drug, capable of inhibiting enzyme specific for pain may be more effective in preventing the tooth sensitivity caused by the inflammatory response produced by in-office…
- Trial name
- NCT01300780
- Testing
- Etoricoxib
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Eloisa Andrade de Paula