Clinical trials: Teeth Sensitivity
Hypersensitivity Dentin
Potassium Nitrate Gel and Diode Laser for Dentinal Hypersensitivity
The goal of this randomized clinical trial is to evaluate whether combining a potassium nitrate gel with diode laser therapy is more effective in treating dentinal hypersensitivity compared to using the gel alone.
- Trial name
- NCT06746558
- Testing
- Potassium Nitrate Gel and Diode Laser Therapy, Potassium Nitrate Gel Alone
- Where
- Italy
- Volunteers
- 12 people
- Sponsor
- University of Modena and Reggio Emilia
Tooth Sensitivity
An Evaluation of the Efficacy of Oral-B New Product Sensi-Stop on Dentinal Hypersensitivity
The purpose of the study is to evaluate the efficacy of Sensi-StopTM strips (Procter \& Gamble™) on the relief of dentinal hypersensitivity.
- Trial name
- SSDH (NCT02476032)
- Testing
- Prof applied oxalate, Self applied oxalate
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Dentin Hypersensitivity
Laser Therapy for Dentin Hypersensitivity
This split-mouth randomized controlled clinical trial compared the effectiveness of Er,Cr:YSGG laser irradiation, a hydroxyapatite- and fluoride-containing agent (Remin Pro), and their combined application in the treatment of…
- Trial name
- NCT07431736
- Testing
- Er,Cr;YSGG Laser, Waterlase, Biolase Technology Inc., Irvine, CA, ABD, Remin Pro (VOCO, Cuxhaven, Germany)
- Where
- Turkey (Türkiye)
- Volunteers
- 25 people
- Sponsor
- Hacettepe University
Dentin Sensitivity
A Study in Dentinal Hypersensitivity (DH) Participants to Assess the Efficacy of an Occluding Dentifrice.
This study will investigate the longitudinal efficacy of two experimental oral rinses, one containing 1.5% weight/weight (w/w) dipotassium oxalate monohydride (KOX) /0 Parts per Million (ppm fluoride) and the other 2.0% w/w KOX…
- Trial name
- NCT02753075
- Testing
- Experimental Oral Rinse 1, Experimental Oral Rinse 2, Fluoride toothpaste
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Tooth Bleaching, Dentin Sensitivity
In-office Bleaching Using a Violet Light
The objective of this clinical study is to evaluate the effect of the whitening treatment performed with the violet LED light (405-410 nm), with or without a bleaching gel, on the tooth color changes (immediate and long-term)…
- Trial name
- NCT03207204
- Testing
- 35% Hydrogen peroxide bleaching, 30% Carbamide peroxide bleaching, Violet LED bleaching 1
- Where
- Brazil
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Diabetes Mellitus, Sarcoidosis
Salivary Proteins in Disease and Health
This study will examine saliva samples from healthy volunteers and patients with various diseases to learn more about how disease affects the mouth and salivary glands.
- Conditions
- Diabetes Mellitus, Sarcoidosis, Dental Caries, Sjorgren's Syndrome
- Trial name
- NCT00100204
- Where
- United States
- Volunteers
- 264 people, healthy volunteers welcome
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Hydrogen Peroxide Allergy
The Effect of Different Drugs in the Prevention of Tooth Sensitivity Caused by Tooth Bleaching Treatment.
Background: The administration of the intra-oral drugs was not capable of reducing this side effect, maybe the use of two analgesics may to present better analgesic effect to avoid the bleaching-induced tooth sensitivity (TS).
- Trial name
- NSAIDs (NCT03343392)
- Testing
- acetam/ketoro tromet group
- Where
- Brazil
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual de Ponta Grossa
Dentin Sensitivity
Nano-hydroxyapatite With Potassium Nitrate in the Therapy of the Dental Sensitivity
The chief aim of this study is to evaluate the difference in tooth sensitivity after having used a gel containing nano - hydroxyapatite and potassium nitrate This randomized double-blind clinical study is designed to compare the…
- Trial name
- NCT02895321
- Testing
- Cavex Bite&White ExSense, Colgate, Protection Caries
- Where
- Italy
- Volunteers
- 35 people
- Sponsor
- Università degli Studi di Sassari
Dentin Sensitivity
In-office Bleaching With a 2-day Interval Between Sessions: Tooth Sensitivity
The calcium containing 35% hydrogen peroxide gel employed in this study can be re-applied 2 days after the first bleaching session without increasing the bleaching-induced tooth sensitivity
- Trial name
- NCT01959789
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual de Ponta Grossa
Molar Incisor Hypomineralization
Interventions to Control Hypersensitivity Pain in Teeth With Insisive Molar Hypomineralization
Molar incisor hypomineralization (MIH) manifests as a qualitative, demarcated defect in tooth enamel of systemic origin, predominantly affecting one or more permanent first molars, and potentially extending to the incisors.
- Trial name
- LBIARHMI (NCT06426108)
- Testing
- Fluoride Varnishes, Low-Intensity Laser 1J, Low-Intensity Laser 2J
- Where
- Brazil
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Tooth Sensitivity
Efficacy of Azadirachta Indica Based Herbal Mouthwash in Treating the Tooth Hypersensitivity
Type of study: Single-blinded clinical trial to evaluate the effectiveness of Azadirachta indica based Herbal mouthwash to treat the tooth sensitivity in patients.
- Trial name
- NCT06288776
- Testing
- Herbal based mouthwash
- Where
- Pakistan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Pakistan Institute of Medical Sciences
Medicaments Substances in Therapeutic Use
Potassium Oxalate and Potassium Nitrate and Post-bleaching Sensitivity
Objectives: This study will determine the effectiveness of the use of desensitivity gels prior in office bleaching on risk and intensity of tooth sensitivity caused by in-office bleaching using 35% hydrogen peroxide.
- Trial name
- NCT02941653
- Testing
- Potassium nitrate 2% gel, Potassium oxalate 5% gel
- Where
- Brazil
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Sergipe
Dentine Hypersensitivity
Comparison of Different Desensitizers in Reducing Dentinal Hypersensitivity
This is a single center, randomized control. Sixty eligible subjects will be recruited into 3 study treatment groups (n=20 per group) through computerized randomization.
- Trial name
- NCT03177109
- Testing
- 5% fluoride varnish, 8% arginine containing paste, Self-adhesive resin
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Aga Khan University
Dentin Hypersensitivity
Hypersensitivity Reduction Efficacy: 5% Potassium Nitrate Toothpaste Compared to Colgate Cavity Protection Toothpaste
Assess the clinical efficacy of 5% Potassium Nitrate Toothpaste (Colgate-Palmolive Company, New York, NY, USA) on providing dentinal hypersensitivity relief (tactile and air blast) in comparison to Colgate Cavity Protection…
- Trial name
- NCT06956599
- Testing
- test toothpaste, Control toothpaste
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Tooth Bleaching, Pain
Effect of Andiroba on Control of Post-whitening Tooth Sensitivity
This randomized clinical trial will evaluate the effect of an experimental gel containing andiroba oil (Carapa guianensis) in reducing postoperative tooth sensitivity caused by bleaching with 35% hydrogen peroxide.
- Conditions
- Tooth Bleaching, Pain, Dentin Desensitizing Agents
- Trial name
- NCT06614764
- Testing
- AG (experimental Andiroba Gel), KF2G (Potassium nitrate gel)
- Where
- Brazil
- Volunteers
- 75 people
- Sponsor
- Universidade Federal do Para
Hypersensitivity, Dentin Sensitivity
Clinical Assessment of Bifluorid 10 vs Varnish Fluoride on The Exposed Hypersensitive Cervical Dentin in Adult Patient
Aim of the study will be conducted to compare the efficacy of bifluoride (NaF and CaF) versus conventional fluoride varnish (Sodium Flouride) in the management of hypersensitivity of exposed cervical area in adult patients over 2…
- Trial name
- NCT04485299
- Testing
- Bifluorid 10 ,VOCO, Sodium Fluoride 5% Dental Varnish
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Pulp Exposure, Postoperative Pain
Diode Laser-Assisted Direct Pulp Capping Trial
This randomized controlled clinical trial evaluates whether adjunctive 808-nm diode laser therapy after direct pulp capping reduces postoperative pain and dentin hypersensitivity compared with conventional Biodentine treatment.
- Conditions
- Dental Pulp Exposure, Postoperative Pain, Dentin Hypersensitivity
- Trial name
- NCT07593508
- Testing
- Biodentine, 808-nm Diode Laser
- Where
- Vietnam
- Volunteers
- 56 people
- Sponsor
- Hue University of Medicine and Pharmacy
Molar Incisor Hypomineralisation, Enamel Hypoplasia
Effect of Resin Infiltration on Hypersensitivity and Satisfaction in Children With Enamel Defects
This study evaluates the effect of resin infiltration on dental sensitivity, quality of life, and satisfaction in children aged 7-14 with enamel defects in their front teeth.
- Conditions
- Molar Incisor Hypomineralisation, Enamel Hypoplasia, Dental Hypersensitivity
- Trial name
- NCT07118111
- Testing
- Resin infiltration
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Gizem Tıraşçı
Dental Restoration Failure of Marginal Integrity
Can Flowable Bulk Fill Composites be Used in Proximal Area of Class II Restorations
Treatment clinical trial, randomized, controlled, parallel, double-blinded, with two groups, that aims to evaluate the best application strategy when using a flowable bulk fill composite (Opus Bulk Fill Flow APS, FGM, Brazil) in…
- Trial name
- OPUSFCLASSII (NCT06183320)
- Testing
- Restoration with Incremental Composite in Proximal Wall, Restoration with Bulk Fill Composite in Proximal Wall
- Where
- Brazil
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Universidade Federal Fluminense
Dentin Hypersensitivity, Periodontal Diseases
Comparative Clinical Evaluation of Three Different Agents in Reducing Dental Hypersensitivity in Periodontal Patients
The present project will compare the effect of DH reduction using three different dentifrices (Sensodyne Repair and Protect - NOVAMIN technology; Dentalclean Daily Regenerator - REFIX technology; Dentalclean Daily Regenerator …
- Trial name
- NCT04422184
- Testing
- Sensodyne Repair and Protect, Dentalclean Daily Regenerator, Dentalclean Daily Regenerator with potassium citrate
- Where
- Brazil
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo