Clinical trials: Temperature
Cardiovascular System
Acute Effects of Cold Exposure on Cardiovascular System
This is a randomized controlled human exposure crossover study. Investigators aim to assess the acute effects of low temperature exposure on cardiovascular system and the underlying mechanisms.
- Trial name
- NCT06652425
- Testing
- Low temperature (15°C) group, Moderate temperature (22°C) group
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Fudan University
Inflammation, Aging
Adaptive Stress Response: The Hot Yoga Study
This is a small intervention study which is aimed at characterizing what is known as the adaptive stress response (also know as "hormesis") in women aged 30-45 years.
- Conditions
- Inflammation, Aging, Depression, Anxiety
- Trial name
- NCT06395376
- Testing
- Bikram Hot Yoga Intervention, Hot Yoga Washout
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Fever, Pain
Bioequivalence Study of Paracetamol With Oral Single Dose Administration in Healthy Adult Subjects Under Fasting Conditions
This study aims to evaluate the bioequivalence of new formulated orodispersible tablet (ODT) containing 500 milligram (mg) paracetamol in comparison to the European marketed Alvedon (paracetamol) 500 mg film-coated tablets and…
- Trial name
- NCT06855576
- Testing
- Paracetamol ODT, Alvedon film-coated tablet, Panadol film-coated Tablet
- Where
- Germany
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- HALEON
Fluid Retention Tissue, Perfusion; Complications
Weightlessness Associated Cephalad Fluid Shifts; The Potential to Evaluate Venous and Lymphatic Dysfunction
In the weightlessness of space and significant alterations of terrestrial 1 g (1 gravity equivalent) head-to-foot hydrostatic pressure gradients, astronauts experience a dramatic fluid redistribution of ~ 2 liters from the legs…
- Trial name
- NIID (NCT06405282)
- Testing
- Manual Lymphatic Drainage, Near infrared spectroscopy, Temperature
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Nova Southeastern University
Vital Signs Monitoring, Newborn Monitoring
Miniaturized Vital Sign Monitoring for Newborns in the Delivery Room
This prospective observational study aims to evaluate the accuracy, safety, and feasibility of the Wireless MicroPremVitals Button Sensor System for continuous monitoring of electrocardiography (ECG), heart rate, respiratory…
- Conditions
- Vital Signs Monitoring, Newborn Monitoring, Physiologic Monitoring
- Trial name
- NCT07739810
- Testing
- Wireless MicroPremVitals Button Sensor
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Signs and Symptoms, Fever
Biomedical Signal Extraction From Symptom Descriptions: An Observational Registry Using the OpenGenome Platform
This registry prospectively collects anonymized free-text symptom descriptions submitted voluntarily by adults through the OpenGenome platform at opengenome.bio.
- Conditions
- Signs and Symptoms, Fever, Myalgia, Skin Diseases
- Trial name
- OGNOME-REG (NCT07578610)
- Testing
- OpenGenome AI Platform
- Where
- Germany
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- OpenGenome
Heart Failure, Hyperthermia
IEEM-Heat and Heart Failure
We will test the hypothesis that increasing skin wetness, and thus evaporative cooling, will attenuate the increase in core body temperature and accompanying cardiac stress during heat wave conditions in individuals with…
- Trial name
- NCT06961929
- Testing
- Control Trial, Water-saturated T-shirt trial, Skin-Wetting Trial
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Temperature Change, Body
Study to Evaluate the Accuracy of the New Monitor of Temperature in Comparison With the Consecrated Thermometers by Literature
This study compares the use of the "SPOT ON" thermometer with the oral, esophageal in participants submitted to general and the oral thermometer to spinal anesthesia, from the pre op, intra and post op stages, evaluating the…
- Trial name
- NCT03057886
- Testing
- Comparative thermometers to compare with a new device
- Where
- Brazil
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Ricardo Caio Gracco De Bernardis
Respiratory Distress, Hypoglycemia
Observational Study of Infants Born at 34 to 37 Weeks of Gestation Until the Age of 1 Year
Late preterm infants are at an increased risk for short and long term morbidity (during the 1st year of life, their neurodevelopmental status may also be delayed as compared to infants born at term).
- Conditions
- Respiratory Distress, Hypoglycemia, Feeding Intolerance, Jaundice
- Trial name
- NCT00550069
- Where
- Israel
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Skin Cancer, Heat Tolerance
Title: ICARUS - Psycho-physiological Profiling of Low and High Heat-resilient Individuals
The escalating environmental heat-stress associated with global warming is a societal challenge with large and potential harmful consequences for humans.
- Conditions
- Skin Cancer, Heat Tolerance, Heat-related Illness, Hyperthermia
- Trial name
- ICARUS (NCT07510061)
- Testing
- Controlled Heat and Ultraviolet Radiation Exposure Protocol
- Where
- 2 sites in Denmark, Greece
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Erectile Dysfunction
Feeling Hot 2: Penile Skin Temperature Measurements of Nocturnal Erections
The Feeling Hot studies focus on the proof-of-principle of using temperature sensing as a tool to detect nocturnal erections. In the Feeling Hot 2 study the penile skin temperature is investigated during nocturnal erections…
- Trial name
- NCT05183620
- Testing
- Feeling Hot sensor system
- Where
- Netherlands
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- St. Antonius Hospital
Heat Stress, Temperature Change, Body
The Impact of Wearing the Hijab on Whole-body Heat Loss During Exercise-heat Stress
The hijab (headscarf and cloak) is a Muslim dress, which covers the head, neck and chest, and conceals the female hair, leaving the face uncovered.
- Trial name
- NCT07174180
- Testing
- Exercise-heat stress with no hijab, Exercise-heat stress with a hijab
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Neurocognitive Disorders, Post Operative Delirium
Safe Brain Initiative, Operationalizing Precision Anaesthesia
Perioperatively, patients experience an unnecessarily high level of side effects associated with their treatment. These side effects include nausea, severe pain, anxiety, and stress.
- Conditions
- Neurocognitive Disorders, Post Operative Delirium, Pain, Nausea
- Trial name
- SBI (NCT05765162)
- Testing
- Patient reported ourcomes
- Where
- Denmark
- Volunteers
- 15,000 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Resting Energy Expenditure
Influence of Ambient Temperature on Resting Energy Expenditure of Healthy Adults
The aim of this study is to investigate the influence of four different ambient temperatures (18, 22, 28, 38°C) on the resting energy expenditure of healthy adults by respiratory gas analysis.
- Trial name
- NCT05505240
- Testing
- Respiratory analysis at cold temperature, Respiratory analysis at room temperature, Respiratory analysis at thermoneutral temperature
- Where
- Germany
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Bonn
Vomiting, Diarrhea
Developing World Study for RotaTeq™ (V260-015)(COMPLETED)
The purpose of the current study is to evaluate whether the vaccine is effective, well-tolerated and immunogenic among infants in developing countries.
- Conditions
- Vomiting, Diarrhea, Fever
- Trial name
- NCT00362648
- Testing
- RotaTeq™ - Rotavirus Vaccine, Live, Oral, Pentavalent
- Volunteers
- 7,504 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Muscle Tonus
Effectiveness of Digital Capacitive Diathermy Versus Ultrasound on Myofascial Trigger Points
The main objective: To compare the effect on muscle tone between the application of digital capacitive diathermy and the application of ultrasound on the myofascial trigger points (MTP) of the upper trapezius muscle.
- Trial name
- NCT03154632
- Testing
- Ultrasound Therapy, Digital Capacitive Diathermy Therapy
- Where
- Spain
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Universidad San Jorge
Body Temperature Changes
Research on "Metabolic Adaptation" in Obese People
Obesity has become a global public health crisis, with 810 million adults classified as obese (BMI ≥ 30 kg/m²) worldwide in 2020. This number is projected to rise to 1.53 billion by 2035.
- Trial name
- NCT07128238
- Testing
- lifestyle intervention
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Shenzhen Institutes of Advanced Technology ,Chinese Academy of Sciences
Sepsis, Fever
Vitamin D Zinc Fever
Zinc and vitamin d deficiency are associated with a state of inflammation/atherosclerosis. There are studies demonstrating an association between vitamin d deficiency and respiratory illnesses.
- Conditions
- Sepsis, Fever, Vitamin D
- Trial name
- NCT01080950
- Where
- Israel
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Assaf-Harofeh Medical Center
Thermometry
Comparison of Three Methods of Taking Temperatures in the Newborn Intensive Care Unit
Preterm infants will have their body temperature measured by three different devices in order to evaluate whether the newest device, a temporal artery scanning thermometer, is accurate for patients in the preterm period.
- Trial name
- NCT01012128
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Christiana Care Health Services
Pain, Postoperative, Numbness
Lidocaine Versus Bupivacaine in Orthognathic Surgery
In this research study, we want to learn more about the impact of two different local anesthetics (bupivacaine and lidocaine) on patient experience following orthognathic (jaw) surgery.
- Conditions
- Pain, Postoperative, Numbness, Temperature Sensation, Perception of Touch
- Trial name
- NCT06450028
- Testing
- 10 cc of 0.25% bupivacaine hydrochloride with 1:200,000 epinephrine, 6.8 cc of 2% lidocaine hydrochloride with 1:100,000 epinephrine
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital