Clinical trials: Temperature
Recurrent Clostridium Difficile Infection, Laboratory Confirmed Clostridium Difficile Infection
Oral Vancomycin Followed by Fecal Transplant Versus Tapering Oral Vancomycin
Recurrent CDI is a growing problem with few treatment options that provide lasting effect. Fecal transplantation has been shown in several case series to be successful in controlling recurrent CDI.
- Trial name
- NCT01226992
- Testing
- Vancomycin, Fecal Transplant
- Where
- Canada
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Sepsis
Infrared Imaging in Septic Illness
The application of infrared thermal imaging in the diagnosis and prognostication of septic illness in adults. During times of severe infection (sepsis), the small blood vessels supplying oxygen and nutrients to the skin and other…
- Trial name
- NCT02855671
- Testing
- Infrared thermal imaging
- Where
- United Kingdom
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- University Hospitals, Leicester
Pain, Postoperative, Healing Surgical Wounds
Comparative Evaluation of Various Patient Centered Outcomes Following Gingival Depigmentation Using Diode LASER in Different Modes: A Randomized Clinical Trial
Purpose of this study is to clinically evaluate and compare various patient centered outcomes using diode LASER in Continuous mode (CW) and Pulsed Mode (PM) using 300µm and 400µm fiber for depigmentation procedure.
- Conditions
- Pain, Postoperative, Healing Surgical Wounds, Analgesia, Temperature Change, Body
- Trial name
- LASER (NCT04217434)
- Testing
- 400 µm fibre length will be used in continuous contact mode, 400 µm fibre length will be used in pulsed contact mode, 300 µm fibre length will be used in continuous mode
- Where
- India
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Krishnadevaraya College of Dental Sciences & Hospital
Yellow Fever, Yellow Fever Immunisation
A Trial to Evaluate the Safety, Reactogenicity, and Immunogenicity of MVA-BN Yellow Fever Vaccine With and Without Montanide ISA-720 Adjuvant in 18-45 Year Old Healthy Volunteers
This study is a multi-center, double-blind, placebo-controlled, Phase I study to evaluate the safety, reactogenicity, tolerability, and immunogenicity of Modified Vaccinia Ankara-Bavarian Nordic-Yellow Fever (MVA-BN-YF) in…
- Trial name
- NCT02743455
- Testing
- ISA-720, MVA Smallpox Vaccine, MVA-BN Yellow Fever Vaccine
- Where
- 2 sites in United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
DYSMENORRHEA
Heat Application on Depression, Anxiety, Menstrual Attitude and Dysmenorrhea
AIM: Establishing the effects of heat application on depression, anxiety, menstrual attitude and severity of dysmenorrhea. METHODS: This randomized controlled prospective experimental trial was conducted with 43 students who were…
- Trial name
- NCT04572555
- Testing
- Heat Treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Balikesir University
Elevated Blood Pressure
Post-exercise Hot Water Immersion to Improve Overnight Blood Pressure
The goal of this clinical trial is to test whether putting a participant's legs in a hot bath after exercise improves blood pressure in people with higher blood pressure. .
- Trial name
- ExHT (NCT06348225)
- Testing
- Exercise, Heat Therapy
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Providence College
Fever, Pain
Bioequivalence Study of Paracetamol With Oral Single Dose Administration in Healthy Adult Subjects Under Fasting Conditions
This study aims to evaluate the bioequivalence of new formulated orodispersible tablet (ODT) containing 500 milligram (mg) paracetamol in comparison to the European marketed Alvedon (paracetamol) 500 mg film-coated tablets and…
- Trial name
- NCT06855576
- Testing
- Paracetamol ODT, Alvedon film-coated tablet, Panadol film-coated Tablet
- Where
- Germany
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- HALEON
Malaria
Clinical Performance Evaluation of Fyodor Urine Malaria Test (UMT)
The purpose of this study is to evaluate the clinical performance of the one-step Fyodor Urine Malaria Test (UMT), to determine its accuracy (sensitivity and specificity) for the diagnosis of Plasmodium falciparum malaria in…
- Trial name
- NCT01921413
- Testing
- Urine Malaria Test
- Where
- Nigeria
- Volunteers
- 1,893 people, healthy volunteers welcome
- Sponsor
- Fyodor Biotechnologies Inc
Surgery
Solution Temperature and Fluid Deficit During Hysteroscopy
Hysteroscopic surgery is widely used for the treatment of gynecological diseases, such as septum, synechiae, polyp and intrauterine fibroids.
- Trial name
- STOFD (NCT05622097)
- Testing
- 0.9% Saline warmed to 37 degrees Celsius, 0.9% Saline warmed to 24 degrees Celsius
- Where
- United States
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Body Temperature Changes, Heat Stress
Initial Stay Times and Heat Mitigation Controls for Uncompensable Occupational Heat Stress - Part III
Occupational heat stress directly threatens workers' ability to live healthy and productive lives. Heat exposed workers are at an elevated risk of experiencing impaired work performance and cognitive function leading to a greater…
- Conditions
- Body Temperature Changes, Heat Stress, Heat Exposure, Heat Fatigue
- Trial name
- NCT06630832
- Testing
- Simulated work in the heat with no cooling during rest breaks, Simulated work in the heat with partial cooling during rest breaks, Simulated work in the heat with full cooling during rest breaks
- Where
- Canada
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Pain
Bupivacaine Digital Blocks: How Long is the Pain Relief and Temperature Elevation?
No one knows how long bupivacaine finger blocks last. Many use bupivacaine with and without epinephrine, but no one knows how the epinephrine affects the duration of the block.
- Trial name
- NCT01698593
- Testing
- Bupivacaine 0.5%, Bupivacaine 0.5% + Epinephrine (1:200,000)
- Where
- Canada
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Lalonde, Donald H., M.D.
Hyperthermia
The Effectiveness of Emergency Room Protocols for Treating Hyperthermia
This study will help us as scientists and clinicians understand how effective commonly used cooling protocols in emergency departments are and which of the protocols is the most effective.
- Trial name
- EDCP (NCT07433036)
- Testing
- Passive cooling, Cooling packs, Ice sheets
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Colorado Springs
Healthy Volunteers
Psychophysical Correlates of Pain Reduction by Topical Analgesic Compounds
Background: Researchers are studying a topical (skin) cream that reduces pain. This is called an analgesic cream. They want to try a new test to better measure how well it works.
- Trial name
- NCT02322164
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Temperature Regulation; Disorder, Fetus or Newborn
Effect of Drying Before Plastic Wrapping on Thermal Losses in Very Preterm Infants at Birth
This is a multicenter, unblinded, randomized controlled trial comparing drying vs. not drying before plastic wrapping for the thermoregulation of very preterm infants at birth.
- Trial name
- NEODRY (NCT05740072)
- Testing
- Drying before wrapping, No drying before wrapping
- Where
- Italy
- Volunteers
- 346 people, healthy volunteers welcome
- Sponsor
- University Hospital Padova
To Verify Tissue Heating and Temperature Stability and Safety Throughout RF Treatment Duration Applied on the Face
Evaluation of Thermal Outcome and Safety of Nuera Tight RF System
The purpose of the study is to verify tissue heating, temperature stability and safety of the Nuera Tight RF device during and after treatment session applied on the face.
- Trial name
- NCT05957029
- Testing
- NuEra Tight RF system
- Where
- 2 sites in United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Lumenis Be Ltd.
Light Color Temperature
Effect of Reduced Light Color Temperature on Postpartum Mothers' Well-being, Breastfeeding Motivation, and Psychological Well-being After Cesarean Section
The aim of this study is to determine the effects of reduced light color temperature on postpartum mothers' well-being, breastfeeding motivation, and psychological well-being after cesarean section.
- Trial name
- NCT07104045
- Testing
- Reduced light color temperature
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Emine Yıldırım
Reaction of Far Infrared Ray, Reaction of Skin Temperature
Far-infrared Ray Effect on CV12 Acupoint
The purpose of the present study was to investigate the effect of far-infrared ray at CV12 acupoints area on the skin temperature and skin blood flow of palm central area of right hand, and the correlation between them.
- Trial name
- NCT01339728
- Testing
- far-infrared ray
- Where
- Taiwan
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Microcirculation
The Effect of Photobiomodulation on Microvascular Blood Flow: The Role of Wavelength and Skin Temperature
The objective of this study is to assess peripheral microcirculatory hemodynamic responses to photobiomodulation in participants with normal circulation and with functional peripheral vasoconstriction, using noninvasive…
- Trial name
- PBM&MBF01 (NCT07338695)
- Testing
- Photobiomodulation - Blue Wavelength, Photobiomodulation - Near Infrared
- Where
- Israel
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Afeka, The Tel-Aviv Academic College of Engineering
Healthy
Temperature Response to a Head-Neck Cooling System
This study will evaluate the effectiveness of a specially designed head-neck cooling system for way lowering the body's central, or core, temperature and cooling the brain.
- Trial name
- NCT00025987
- Testing
- Head and Neck Cooling System, Thermometer Pill
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Climate Change, Heat; Weather
Heat Adaptation Through Community-based Approaches and Research at SEACO: Structural and Behavioural Interventions (Heat Care)
The goal of this clinical trial is to learn if structural and behavioral interventions can mitigate the health effects of extreme heat in rural Malaysian communities.
- Conditions
- Climate Change, Heat; Weather, Heat Effect, Heat; Excess
- Trial name
- Heat Care (NCT06744309)
- Testing
- Heat Literacy Intervention, Structural (Cool Roof) Intervention
- Where
- Malaysia
- Volunteers
- 1,110 people, healthy volunteers welcome
- Sponsor
- Monash University Malaysia