Clinical trials: Temporal Bone
Normal CT Scan, Dysplasic Disease
Dose-Quality Study in the Temporal Bone Computed Tomography in Routine Care
Because of the complexity of the structures studied, imaging the temporal bone requires compliance with a number of image quality criteria, in order to achieve optimum spatial resolution of the most clinically relevant anatomical…
- Conditions
- Normal CT Scan, Dysplasic Disease, Tumoral Disease, Infectious Disease
- Trial name
- NCT06827106
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Aix Marseille Université
Lumbar Disc Herniation, Lumbar Radiculopathy
The Role of Temporal Changes in Pain Response After Transforaminal Epidural Steroid Injection on Treatment Success
Transforaminal epidural steroid injection (TFESI) is a commonly used minimally invasive procedure for the treatment of lumbar radicular pain secondary to disc herniation.
- Conditions
- Lumbar Disc Herniation, Lumbar Radiculopathy, Radicular Low Back Pain, Sciatica
- Trial name
- NCT07367191
- Testing
- Transforaminal epidural steroid injection
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Marmara University
User-Computer Interface, Clinical Skills
Establishing Learning Curves in Virtual Simulation Training of Mastoidectomy
The purpose of this study is to establish learning curves of mastoidectomy training in virtual surgical simulation training, to establish the long-term effect of repeat simulation training and to explore the transfer of skills…
- Conditions
- User-Computer Interface, Clinical Skills, Motor Skills, Temporal Bone
- Trial name
- NCT01966185
- Testing
- Tutor function on
- Where
- Denmark
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Reconstruction of the Posterior Membranous Labyrinth
3D Model of Posterior Membranous Labyrinth of the Inner Ear
The aim of this work is to create a three-dimensional (3D) finite element model (FEM) of the human posterior membranous labyrinth, based on in vivo inner ear magnetic resonance imaging (MRI).
- Trial name
- NCT03295929
- Where
- France
- Volunteers
- 1 people
- Sponsor
- University Hospital, Strasbourg, France
Hypertension, Fracture
Immediate Fracture Risk After Antihypertensive Drug Initiation
This retrospective observational study aims to evaluate the short-term fracture risk associated with anti-hypertensive medication initiation using a self-controlled case series (SCCS) design and investigate temporal trends of…
- Trial name
- FADI (NCT06964217)
- Testing
- Monotherapy, Combination therapy
- Volunteers
- 10,000,000 people
- Sponsor
- Ajou University School of Medicine
Cochlear Implantation
Impact of the Surgical Experience on Cochleostomy Location: A Comparative Temporal Bone Study Between Endaural and Posterior Tympanotomy Approaches for Cochlear Implantation
The goal of this study was to evaluate, in the hands of an inexperienced surgeon, the cochleostomy location of an endaural approach (MINV) compared to the conventional posterior tympanotomy (MPT) approach.
- Trial name
- NCT02902497
- Volunteers
- 24 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Epilepsy
Autologous Bone Marrow Stem Cells Transplantation in Patients With Temporal Lobe Epilepsy
This research investigates the use of autologous bone marrow stem cells for the treatment of medically refractory temporal lobe epilepsy patients.
- Trial name
- NCT00916266
- Testing
- Stem cell transplantation
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- Instituto do Cerebro de Brasilia
Focus: Otologic Surgery Training
Virtual Temporal Bone Surgery: Defining and Translating Metrics
The goal of this project is to improve the efficiency of training and assessment of technical skill in surgical treatment of otologic disease.
- Trial name
- NCT01493765
- Testing
- Simulator training with expert scoring
- Where
- 10 sites in United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Nationwide Children's Hospital
Medical Education, User-Computer Interface
The Effect of Virtual Simulation Training in Mastoidectomy
The purpose of this study is to investigate the effect of virtual simulation training on mastoidectomy dissection performance of otorhinolaryngology trainees, to explore performance assessment using a final-product analysis…
- Conditions
- Medical Education, User-Computer Interface, Clinical Skills, Motor Skills
- Trial name
- NCT02030873
- Testing
- Virtual simulation training
- Where
- Denmark
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Pain, Lumbar Disc Herniation
The Diagnostic and Prognostic Value of Two Quantitative Clinical Tests in Patients With Lumbar Disc Herniation
This study will investigate whether two clinical tests can be used to diagnose and predict the outcome in patients with lumbar disc herniation undergoing surgery and non-surgery treatment.
- Conditions
- Pain, Lumbar Disc Herniation, Back Pain, Spinal Diseases
- Trial name
- NCT03832036
- Testing
- Paraspinal Mapping and Quantitative Sensory Pain Test
- Where
- Denmark
- Volunteers
- 102 people
- Sponsor
- Spine Centre of Southern Denmark
Otosclerosis
Interest of Using Deep Learning Algorithm for Otosclerosis Detection on Temporal Bone High Resolution CT
Otosclerosis is a relatively frequent pathology, of multifactorial origin with genetic and hormonal part, predominantly in women.
- Trial name
- OtoIA (NCT05987215)
- Testing
- Radiologic diagnosis, Artificial intelligence diagnosis
- Where
- France
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Computer Simulation, Education
Validation/Dissemination Of A Temporal Bone Dissection Simulator
Designed to test the efficacy of a computer based virtual simulation for teaching ear surgery.
- Trial name
- NCT00887185
- Testing
- Simulator training for temporal bone surgery
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Gregory Wiet
Displacement of Other Bone Devices, Implants and Grafts, Mechanical Complication of Other Bone Devices, Implants and Grafts
Influence of Low-level Laser Therapy on Stability and Displacement of Orthodontic Miniscrew Implants
The purpose of this study is to evaluate the effect of Low level laser therapy on stability and displacement of orthodontic miniscrew implants using two different force application protocols.
- Trial name
- NCT02891499
- Testing
- Low-level laser therapy, Mediate force application
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Enlarged Vestibular Aqueduct, Sensorineural Hearing Loss
Enlarged Vestibular Aqueduct Registry
People with the congenital anatomical malformation known as "Enlarged Vestibular Aqueduct" (EVA) may experience decline in hearing ability.
- Trial name
- EVAR (NCT02798783)
- Where
- United States
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Spine Fracture
Three Dimensional Gait Analysis and Electromyography After Stabilisation of Thoracolumbar Spine Fractures Focusing on Possible Temporal Diferences in Physiological Gait Recovery Through Comparison of Open and Minimally Invasive Approaches.
We prospectively enrolled patients with a thoracic or lumbar spine fracture indicated for instrumented posterior stabilization. We consequently randomized the patient for either a conventional open approach procedure or minimally…
- Trial name
- NCT07516834
- Testing
- spine stabilization
- Where
- Czechia
- Volunteers
- 20 people
- Sponsor
- Masarykova Nemocnice v Usti nad Labem, Krajska Zdravotni a.s.
Otitis Media Chronic, Temporal Bone
Efficacy of Platelet- and Extracellular Vesicle-rich Plasma in Chronic Postsurgical Temporal Bone Inflammations
This clinical study evaluates the efficacy of the autologous blood-derived product called platelet- and extracellular vesicle-rich plasma (PVRP) for the treatment of chronically inflamed post-surgical temporal bone cavities.
- Trial name
- PvRP-ear (NCT04281901)
- Testing
- Platelet- and extracellular vesicle-rich plasma, Standard conservative treatment
- Where
- Slovenia
- Volunteers
- 25 people
- Sponsor
- University Medical Centre Ljubljana
Conductive Hearing Loss
Interest of the Cone Beam Scanner of Temporal Bones in the Analysis of Conductive Hearing Loss
Conductive hearing loss is very common and the incidence increases with age. Until now, the scanner was the reference examination in the etiological diagnosis of deafness.
- Trial name
- Cone-Beam (NCT06164184)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Strasbourg, France
Otosclerosis of Middle Ear, Bone Density
Investigating the Relationship Between Temporal Bone CT, Bone Density, and Hearing Loss in Otosclerosis Patients
The goal of this observational case-control study is to evaluate the relationship between temporal bone computed tomography (CT) findings, bone mineral density (BMD), and audiological parameters in adults diagnosed with…
- Conditions
- Otosclerosis of Middle Ear, Bone Density, Vitamin D Deficiency
- Trial name
- NCT06830187
- Where
- Turkey (Türkiye)
- Volunteers
- 86 people
- Sponsor
- İbrahim Emir Yeşil
Temporal Bone Abnormalities
CT Temporal Bone Anatomical Variations
This study aimed to identify the prevalence of normal variations of temporal bone anatomy on high-resolution CT imaging and discuss their clinical importance
- Trial name
- NCT06597877
- Testing
- CT
- Volunteers
- 100 people
- Sponsor
- Assiut University
Facial Nerve Paralysis
Multislice Computed Tomography in Cases With Facial Nerve Paralysis Due to Temporal Bone Trauma
Facial nerve paralysis is a disfiguring complication which occurs in 7-10 % of temporal bone fractures. The onset of paralysis may be immediate, delayed or undetermined, the latter of which often occurs in unconscious patients…
- Trial name
- NCT03469427
- Where
- Egypt
- Volunteers
- 15 people
- Sponsor
- Assiut University