Clinical trials: Temporal Interference Stimulation (TIS), open to volunteers
Healthy Controls
Temporal Interference Stimulation for Social Cognition
The long-term goal of this project is to evaluate whether a procedure termed transcranial interference stimulation (tIS) may be useful in the future in the treatment of severe neuropsychiatric disorders such as schizophrenia.
- Trial name
- TISSC (NCT06607432)
- Testing
- Transcranial Interference Stimulation (tIS)
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Columbia University
Temporal Interference Stimulation (TIS), Parkinson's Disease
Study on the Efficacy of Temporal Interference Stimulation (TIS) for Parkinson's Disease
The primary objective of this clinical study is to evaluate the therapeutic efficacy of Temporal Interference Stimulation (TIS), a non-invasive deep brain stimulation technique, in patients with Parkinson's disease, and to…
- Trial name
- NCT07312279
- Testing
- TIS
- Volunteers
- 24 people
- Sponsor
- Zhongnan Hospital
Temporal Interference Stimulation, Non Suicidal Self Injury
TIS for NSSI in Adolescent Depression
Temporal Interference Stimulation (TIS) has been successfully used to help patients with depression. However, its role in alleviating self injuries remained uncertain.
- Conditions
- Temporal Interference Stimulation, Non Suicidal Self Injury, Major Depressive Disorder
- Trial name
- NCT07554755
- Testing
- Active Temporal Interference Stimulation (TIS)
- Where
- China
- Volunteers
- 60 people
- Sponsor
- The Second Hospital of Anhui Medical University
Epilepsy
TIS for Drug Resistant TLE
Temporal interference (TI) stimulation is a new neuromodulation method. Compared with traditional neuromodulation therapy, TI has deep targeting and focusing, and it has been confirmed to modulate sleep, cognition, and movement…
- Trial name
- TITE-Effect (NCT07519018)
- Testing
- TI Stimulation
- Volunteers
- 30 people
- Sponsor
- Xijing Hospital
Depressive Disorder, Temporal Interference Stimulation
Intervention Effect of Temporal Interference Stimulation (TIS) on Depressive Disorder
To investigate the effect of Temporal Interference Stimulation (TIS) on associative memory (AM) in patients with depressive disorder
- Trial name
- NCT07191392
- Testing
- Temporal Interference Stimulation (TIS)
- Where
- 2 sites in China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The Second Hospital of Anhui Medical University
Schizophrenia Disorder, Cognitive Impairments
TIS for Improving Cognitive Impairment in Schizophrenia
This study aims to evaluate the efficacy, safety, and underlying neural mechanisms of TIS targeting the hippocampus in ameliorating cognitive impairment associated with schizophrenia (CIAS).
- Trial name
- NCT07647380
- Testing
- temporal interference stimulation
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Central South University
Mild Cognitive Impairment (MCI)
Hippocampal Temporal Interference Stimulation for Memory and Dual-Task Postural Control in Older Adults With Mild Cognitive Impairment
This trial aims to investigate whether a single session of 40 Hz hippocampal temporal interference stimulation can improve memory function and dual-task postural control among older adults with mild cognitive impairment (MCI).
- Trial name
- NCT07771036
- Testing
- Temporal Interference Stimulation
- Where
- China
- Volunteers
- 21 people
- Sponsor
- Shanghai University of Sport
Neuropathic Pain, tTIS
Effects and Mechanisms of Temporal Interference Stimulation (TIS) on Neuropathic Pain
This study employs temporal interference stimulation (tTIS) to investigate the analgesic effects of tTIS on neuropathic pain and monitor changes in neural plasticity, and explore the dynamic relationship between analgesic…
- Trial name
- TIS (NCT07735975)
- Testing
- Transcranial temporal interference stimulation
- Volunteers
- 60 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
PARKINSON DISEASE (Disorder)
TIS for Brain Network Modulation and Clinical Efficacy in Parkinson's Disease
Parkinson's disease (PD) is a neurodegenerative disorder characterized by motor dysfunction. While deep brain stimulation (DBS) is effective, its invasive nature limits its application in early-stage patients.
- Trial name
- PD TIS (NCT07480317)
- Testing
- Temporal Interference Stimulation (130 Hz), Temporal Interference Stimulation (40 Hz)
- Where
- China
- Volunteers
- 75 people
- Sponsor
- Jiangsu Province Nanjing Brain Hospital
PARKINSON DIS
Comparative Study of TIS Efficacy Across Different Targets
This prospective, randomized, participant- and outcome-assessor-blinded, parallel-group exploratory trial will compare the target-dependent clinical, neuroimaging, and electrophysiological effects of temporal interference…
- Trial name
- tTIS (NCT07745673)
- Testing
- TIS-STN, TIS-GP
- Where
- China
- Volunteers
- 18 people
- Sponsor
- Zhongnan Hospital