Clinical trials: Temporal Lobe Epilepsy (TLE)
Temporal Lobe Epilepsy (TLE)
MRI Volumetry and Diffusion Tensor Imaging in Temporal Lobe Epilepsy
This works aims at evaluating the diagnostic performance of combined MRI Volumetry, Diffusion tensor imaging and Conventional MRI in lateralizing the epileptogenic focus in patients with temporal lobe epilepsy and correlate these…
- Trial name
- NCT07384351
- Testing
- MRI
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Assiut University
Temporal Lobe Epilepsy (TLE), Drug Resistant Epilepsy
Overnight TI in TLE
The goal of this clinical trial is to gauge whether overnight, non-invasive temporal interference (TI) stimulation aimed at the hippocampus can reduce abnormal brain activity linked to seizures and improve sleep in adults with…
- Conditions
- Temporal Lobe Epilepsy (TLE), Drug Resistant Epilepsy, Sleep
- Trial name
- TI-HPC-TLE (NCT07434986)
- Testing
- Non-invasive Temporal Interference (TI) Stimulation Targeting Bilateral Hippocampi
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Duke University
Temporal Lobe Epilepsy
Autonomic Dysfunction in Temporal Lobe Epilepsy and SUDEP
The study aimed at detection of autonomic dysfunction among cases with temporal lobe epilepsy; using different electrophysiological techniques.
- Trial name
- NCT06269822
- Testing
- Sympathetic skin response, heart rate variability test, quantitative EEG
- Where
- Egypt
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Cairo University
Mild Cognitive Impairment (MCI), Alzheimer Disease (AD)
Biomarkers in Neurodegenerative Diseases
The general purpose of this observational study is to examine biomarkers associated with the pathology of neurodegenerative diseases to potentially develop novel therapeutic approaches.
- Conditions
- Mild Cognitive Impairment (MCI), Alzheimer Disease (AD), Dementia With Lewy Bodies (DLB), Frontotemporal Lobar Degeneration (FTLD)
- Trial name
- NCT04055532
- Testing
- Neuraceq
- Where
- United States
- Sponsor
- University of Minnesota
Epilepsy, Temporal Lobe
A Deep Learning Framework for Pediatric TLE Detection Using 18F-FDG-PET Imaging
This study aims to use radiomics analysis and deep learning approaches for seizure focus detection in pediatric patients with temporal lobe epilepsy (TLE).
- Trial name
- NCT04169581
- Where
- China
- Volunteers
- 201 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Temporal Lobe Epilepsy (TLE)
MRgLITT for mTLE: A PROBE Trial
How does magnetic resonance-guided laser interstitial thermal therapy (MRgLITT) impact clinical prognosis in mesial temporal lobe epilepsy (mTLE)?
- Trial name
- MINE (NCT06720922)
- Testing
- Resonance-guided Laser Interstitial Thermal Therapy (MRgLITT), Open Surgery
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Beijing Tiantan Hospital
Epilepsy
TIS for Drug Resistant TLE
Temporal interference (TI) stimulation is a new neuromodulation method. Compared with traditional neuromodulation therapy, TI has deep targeting and focusing, and it has been confirmed to modulate sleep, cognition, and movement…
- Trial name
- TITE-Effect (NCT07519018)
- Testing
- TI Stimulation
- Volunteers
- 30 people
- Sponsor
- Xijing Hospital