Clinical trials: Temporomandibular Disorder
Temporomandibular Joint Dysfunction; Myofascial Pain Syndrome; Orofacial Pain; Musculoskeletal Disorders
Reflex Therapy of Temporomandibular Dysfunctions
This study aims to evaluate the effectiveness of dry needling in patients with functional temporomandibular pain syndrome by comparing standard rehabilitation therapy alone with therapy combined with dry needling to reduce pain…
- Trial name
- NCT07321483
- Testing
- Dry needling, Standard rehabilitation
- Where
- Czechia
- Volunteers
- 100 people
- Sponsor
- Palacky University
Temporomandibular Disorders
Temporomandibular Disorders With and Without Chronic Neck Pain
Temporomandibular disorders (TMD) are common musculoskeletal conditions frequently accompanied by cervical dysfunction. Although previous studies have demonstrated associations between cervical impairments and temporomandibular…
- Trial name
- NCT07750743
- Where
- Turkey (Türkiye)
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Temporomandibular Disorders (TMD), Temporomandibular Joint Disc Displacement, With Reduction
Long-term Follow up of TMJ Surgery and Evaluation of the 6-month Control as a Prognostic Marker.
The goal of this clinical trial is to evaluate the long-term outcome of surgical intervention (arthroscopy or discectomy) due to the diagnoses temporomandibular joint disc displacement with or without displacement.
- Conditions
- Temporomandibular Disorders (TMD), Temporomandibular Joint Disc Displacement, With Reduction, Temporomandibular Joint Disc Displacement, Without Reduction
- Trial name
- NCT06782165
- Testing
- Arthroscopy & saline irrigation alone, Discectomy
- Where
- Sweden
- Volunteers
- 91 people
- Sponsor
- Karolinska Institutet
Temporomandibular Disorders (TMDs), Kinesiophobia
The Italian Version of the Tampa Scale for Kinesiophobia for Temporomandibular Disorders (TSK-TMD)
This observational, cross-sectional study aims to translate, culturally adapt, and psychometrically validate the Italian version of the Tampa Scale for Kinesiophobia for Temporomandibular Disorders (TSK-TMD-ITA).
- Trial name
- TSK-TMD-ITA (NCT07750509)
- Volunteers
- 250 people
- Sponsor
- Alessandro Aquino
Temporomandibular Joint Disc Displacement, Temporomandibular Joint Disc Displacement, Without Reduction
TMJ Arthroscopy Compared to Arthrocentesis in Disc Displacement Without Reduction
The goal of this clinical trial is to compare the intervention arthroscopic lysis and lavage to the intervention arthrocentesis in treating disabling and painful temporomandibular joint disc displacement without reduction.
- Conditions
- Temporomandibular Joint Disc Displacement, Temporomandibular Joint Disc Displacement, Without Reduction, Temporomandibular Disorders (TMD)
- Trial name
- ACALL (NCT06782178)
- Testing
- Arthroscopic lysis and lavage, Arthrocentesis/Saline
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Karolinska Institutet
Temporomandibular Joint Disc Displacement, With Reduction, Temporomandibular Disorders (TMD)
TMJ Arthroscopic Lysis and Lavage Compared to Operative Arthroscopy in Disc Displacement With Reduction.
The goal of this clinical trial is to compare the intervention arthroscopic lysis and lavage to the intervention operative arthroscopy in treating disabling and painful temporomandibular joint disc displacement with reduction.
- Trial name
- ALLOAA (NCT06782191)
- Testing
- Arthroscopic lysis and lavage, Operative arthroscopy
- Where
- Sweden
- Volunteers
- 96 people
- Sponsor
- Karolinska Institutet
Temporomandibular Disorders (TMD)
The Effects of Pilates Exercises on Women With Myogenic Temporomandibular Joint Dysfunction: A Randomised Controlled, Single-Blind Study
The aim of this study is to investigate the effects of an 8-week Pilates exercise program on pain, pressure-pain threshold, temporomandibular joint (TMJ) range of motion, cervical posture, stress levels, quality of life, jaw…
- Trial name
- TMD (NCT07750145)
- Testing
- Pilates, Education and home exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Toros University
Temporomandibular Disorders
Peripheral TMD Pain Mechanisms and the Effect by Botulinum Toxin A
The goal of this clinical trial is to investigate the effect of botulinum toxin on neurons' plasticity in the masseter muscle in humans with and without painful myogenous temporomandibular disorders (TMDM).
- Trial name
- NCT05720065
- Testing
- Botulinum toxin type A, Isotonic saline 0,9%
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Karolinska Institutet
Temporomandibular Disorders (TMD), Manual Therapy
Effectiveness of the Fascial Distortion Model in Temporomandibular Disorders: A Randomized Sham-controlled Trial
The aim of the study was to investigate the effectiveness of Manual Therapy Based on the Fascial Distortion Model in individuals with temporomandibular disorders compared to sham control.
- Conditions
- Temporomandibular Disorders (TMD), Manual Therapy, Fascial Distortion
- Trial name
- NCT06627855
- Testing
- Fascial Distortion Model
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Karabuk University
Myogenic Temporomandibular Joint Disorders, Myofacial Pain
Efficacy of PRP Injections in Reducing Pain for Myogenous TMD Patients
This study aims to evaluate whether intramuscular injections of platelet-rich plasma (PRP) are more effective than isotonic saline in reducing pain and improving jaw function in individuals diagnosed with myogenous…
- Conditions
- Myogenic Temporomandibular Joint Disorders, Myofacial Pain, Masseter Muscle
- Trial name
- NCT07606378
- Testing
- Saline (0.9% NaCl), Platelet rich plasma (PRP)
- Where
- Sweden
- Volunteers
- 50 people
- Sponsor
- Karolinska Institutet
Temporomandibular Joint Dysfunction
MASSETER MUSCLE EVALUATION AFTER TEMPOROMANDIBULAR JOINT ARTHROCENTESIS
ULTRASONOGRAPHIC AND ELASTOGRAPHIC EVALUATION OF THE MASSETER MUSCLE AFTER TEMPOROMANDIBULAR JOINT ARTHROCENTESIS
- Trial name
- TMJ (NCT07744100)
- Testing
- TEMPOROMANDIBULAR JOINT ARTHROCENTESIS
- Volunteers
- 50 people
- Sponsor
- sema kaya
Temporomandibular Disorders (TMD)
Transcutaneous Electrical Nerve Stimulation for Early Pain Control in Temporomandibular Disorders
To evaluate whether adding conventional transcutaneous electrical nerve stimulation (TENS) to a standard conservative regimen (patient education, pharmacotherapy, and a home exercise programme) provides additional short- and…
- Trial name
- NCT07744893
- Testing
- Standard Conservative Therapy, Transcutaneous Electrical Nerve Stimulation (TENS)
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Balikesir University
Temporomandibular Disorder (TMD), Cervical Vertebrae
Morphometric and Morphological Analysis of Cervical Vertebrae in Disc Displacement
Temporomandibular disorders (TMDs) are multifactorial clinical conditions affecting the masticatory muscles, the temporomandibular joint (TMJ), and the surrounding structures.
- Conditions
- Temporomandibular Disorder (TMD), Cervical Vertebrae, Disc Displacement, Dentistry
- Trial name
- TMJ (NCT07429435)
- Testing
- cephalometric analysis
- Where
- Turkey (Türkiye)
- Volunteers
- 115 people
- Sponsor
- Kutahya Health Sciences University
Bruxism, Temporomandibular Disorders (TMD)
Short-Term Symptom Changes in Adults With Teeth Clenching or Grinding and Jaw Symptoms Receiving Splint, Botulinum Toxin, or Medication Plus Splint Care
This prospective observational study evaluated short-term patient-reported symptom changes in adults with bruxism-related and temporomandibular disorder symptoms who received one of three clinically selected management…
- Conditions
- Bruxism, Temporomandibular Disorders (TMD), Myofascial Pain
- Trial name
- NCT07586072
- Testing
- Occlusal splint, Botulinum Toxin Type A (Dysport®), Thiocolchicoside
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Recep Tayyip Erdogan University
Temporomandibular Joint Disorders, Temporomandibular Joint Dysfunction Syndrome
Arthrocentesis Versus Botulinum Toxin Injection in Patients With Temporomandibular Joint Disorders: A Randomized Controlled Trial
The goal of this clinical trial is to learn if arthrocentesis works as well as botulinum toxin (Botox) injection to treat pain and jaw dysfunction in adults with temporomandibular joint (TMJ) disorders.
- Conditions
- Temporomandibular Joint Disorders, Temporomandibular Joint Dysfunction Syndrome, Facial Pain
- Trial name
- RCT (NCT07736521)
- Testing
- Arthrocentesis, Botulinum Toxin-A
- Volunteers
- 66 people
- Sponsor
- Mudher MB Alsunbuli
Temporomandibular Disorders (TMD), Muscle Pain
Autologous Exosomes From Platelet-rich Plasma as a Modern Tool of Regenerative Dentistry
The aim of the research is the laboratory assessment of the content as well as the regenerative and anti-inflammatory potential of autologous exosomes (EXO) from platelet-rich plasma (PRP), as well as their comparison with other…
- Conditions
- Temporomandibular Disorders (TMD), Muscle Pain, TMJ Pain
- Trial name
- NCT07511959
- Testing
- Laboratory analysis of the content and biological activity of PRP, PRF, and exosomes obtained from blood samples
- Where
- Poland
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Wroclaw Medical University
Chronic Pain, Temporomandibular Joint Disorders
Brain Connectivity Patterns in Chronic Temporomandibular Joint Disorders
This study addresses the timely problem of painful temporomandibular disorders (TMD), the most common cause of orofacial pain second only to tooth pain.
- Conditions
- Chronic Pain, Temporomandibular Joint Disorders, Temporomandibular Joint Pain
- Trial name
- NCT05068908
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Temporomandibular Disorder, Depression
Determination of Chronic Pain, Anxiety, Depression and Perceived Stress in Adults With Temporomandibular Disorders
The aim of the study was to asses levels and relationship of chronic pain, anxiety, depression and perceived stress in TMD patients .
- Conditions
- Temporomandibular Disorder, Depression, Anxiety, Pain
- Trial name
- NCT05183503
- Testing
- DC/TMD examination
- Where
- Poland
- Volunteers
- 219 people
- Sponsor
- Wroclaw Medical University
Temporomandibular Disorder, Temporomandibular Joint Disorders
Effectiveness of iPRF Injections in Temporomandibular Joints Degeneration Management
The aim of the study is to evaluate the effectiveness of intra-articular platelet-rich fibrin (iPRF) injections in the management of moderate and mild cases of degeneration of the temporomandibular joints.
- Conditions
- Temporomandibular Disorder, Temporomandibular Joint Disorders, Temporomandibular Arthritis, Temporomandibular Joint Osteoarthritis
- Trial name
- NCT05214924
- Testing
- Injectable platelet-rich fibrin, Platelet-rich plasma
- Where
- Poland
- Volunteers
- 42 people
- Sponsor
- Wroclaw Medical University
Sleep Bruxism, Sleep Disorder
Relationship Between Selected Parameters and Bruxism
Bruxism is a common phenomenon. It is estimated that its prevalence in the adult population is 8-31%. Bruxism occurring during sleep is the activity of the masticatory muscles that appear during sleep, which can be rhythmic or…
- Conditions
- Sleep Bruxism, Sleep Disorder, Psychosomatic Disorder, Pain
- Trial name
- WMU1/2019 (NCT04214561)
- Testing
- Polysomnography
- Where
- Poland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Wroclaw Medical University