Clinical trials: Tendon Injuries
Rotator Cuff Tears
Safety and Efficacy of Adult Adipose-Derived Stem Cell Injection Into Partial Thickness Rotator Cuff Tears
Extension Study of Protocol RC-001- Safety and Efficacy of Adult Adipose-Derived Stem Cell Injection into Partial Thickness Rotator Cuff Tears.
- Trial name
- NCT04077190
- Testing
- Adipose-derived stem cells, cortisone injection
- Where
- 2 sites in United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- InGeneron, Inc.
Rotator Cuff Related Shoulder Pain, Impingement Syndrome
Effectiveness of Pain Neuroscience Education in Rotator Cuff Related Shoulder Pain
The aim of this randomized controlled trial was to investigate the effects of pain neuroscience education added to exercise on pain intensity, disability, pain threshold, pain catastrophizing, pain beliefs, pain knowledge, and…
- Conditions
- Rotator Cuff Related Shoulder Pain, Impingement Syndrome, Shoulder Tendinopathy
- Trial name
- NCT06677450
- Testing
- Pain neuoroscience education, Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Rotator Cuff Tears, Shoulder Pain
Liposomal Bupivacaine Plus Bupivacaine Peripheral Nerve Blockade Versus Ropivacaine Plus Dexamethasone Peripheral Nerve Blockade for Arthroscopic Rotator Cuff Repair
This study is a comparison of analgesia effect from peripheral nerve blockade (PNB) with liposomal bupivacaine combined with bupivacaine compared to PNB with ropivacaine combined with dexamethasone for arthroscopic rotator cuff…
- Trial name
- NCT04737980
- Testing
- Liposomal bupivacaine, Bupivacaine Hcl 0.5% Inj, Ropivacaine 0.5% Injectable Solution
- Where
- United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Hospital for Special Surgery Florida
Tennis Elbow, Epicondylitis, Lateral Humeral
Relationships Between Ultrasound Data and the Impact of Lateral Epicondylar Pain
Our primary objective is to study the relationship between ultra sound data and the pain associated with tennis elbow.
- Trial name
- EPICORE (NCT01390454)
- Testing
- Ultrasound of the elbow 1, days 7 to 15, Ultrasound of the elbow 2, days 7 to 15, Ultrasound of the elbow 3, days 45 to 90
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Elasticity Imaging Techniques, Tendinopathy
Discriminative Validity of Strain Elastography of the Supraspinatus Tendon
This study aims at testing the discriminative validity of strain elastography in the normal and abnormal/pathological Supraspinatus tendon due to tendinopathy
- Conditions
- Elasticity Imaging Techniques, Tendinopathy, Rotator Cuff Tendinitis, Musculoskeletal Disease
- Trial name
- NCT03425344
- Testing
- Diagnostic
- Where
- Denmark
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Karen Brage
Rotator Cuff Tear
Rotator Cuff Repair Using Standard Double Row Technique With Platelet Rich Fibrin Membrane vs. Standard Double Row Technique
This study is a single-blind, randomized study evaluating the 6 month and 2 year outcomes of patients treated with arthroscopic rotator cuff repair using one of two techniques.
- Trial name
- RCRPRFM (NCT02256891)
- Testing
- PRFM, Double Row
- Where
- United States
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- HealthPartners Institute
Rotator Cuff Tears
Ortho-R® for Rotator Cuff Repair Compared With Standard of Care Rotator Cuff Repair Without Ortho-R®
Phase I/II, multi-center, prospective, blinded 2arm, parallel design and randomized controlled study. Assessing the Ortho-R/PRP combination and standard of care for rotator cuff repair, will be compared though 12 months.
- Trial name
- NCT05333211
- Testing
- Ortho-R/PRP
- Where
- 9 sites in United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- ChitogenX Inc
Shoulder Pain Chronic, Shoulder Pain
Arthroscopic Transosseous vs. Anchored Rotator Cuff Repair
This study will compare arthroscopic transosseous versus anchored rotator cuff repairs in terms of clinical outcomes, rotator cuff integrity, and cost-effectiveness.
- Conditions
- Shoulder Pain Chronic, Shoulder Pain, Rotator Cuff Tear, Rotator Cuff Injury
- Trial name
- NCT03797287
- Testing
- Tensor Tunnler, Anchor Rotator Cuff Repair
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Rotator Cuff Tear
Influence of Intraoperative Repair Tension on Postoperative Healing of Full-thickness Rotator Cuff Tears
Relevant problems of rotator cuff repair: High retear rate after rotator cuff repair of 13%, despite regard of the criteria for "reparability" of a tear.
- Trial name
- TENS-RCT (NCT03318627)
- Testing
- Sterile Spring Scale
- Volunteers
- healthy volunteers welcome
- Sponsor
- Balgrist University Hospital
Muscle Injury
Improving Tissue Repair After Injury in the Muscle-tendon Interface Muscle Tissue Injury
The study is a 2-week human study where 40 patients who are scheduled to undergo reconstructive knee surgery are randomized to administration of GH or placebo following or without neuromuscular electrical stimulation of hamstring…
- Trial name
- GH-MTJ (NCT05746650)
- Testing
- Electrical stimulation, Growth hormone (somatropin), Control (No electrical stimulation, nor growth hormone)
- Where
- Denmark
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Bispebjerg Hospital
Shoulder Injuries, Patient Satisfaction
Conjoint Tendon Resection During Reverse Total Shoulder Arthroplasty
Reverse total shoulder arthroplasty (RTSA) can reliably restore active forward elevation, abduction, and external rotation, which are often lost in patients with massive rotator cuff tears.
- Conditions
- Shoulder Injuries, Patient Satisfaction, Internal Rotation Contracture-shoulder
- Trial name
- NCT05753904
- Testing
- Conjoint Tendon Resection
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Rotator Cuff Tears
Shoulder Functional Performance After Shoulder Surgery
Rotator Cuff (RC) injuries are a progressive clinical condition that starts with an acute tendonitis, continues with partial thickness rupture and results in a full thickness rupture in the advanced period.
- Trial name
- NCT04388306
- Testing
- Shoulder Performance Test- Functional Impairment Test-Head and Neck, Shoulder, Arm (FIT-HaNSA)
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Sports Injury, Anterior Cruciate Ligament Rupture
Comparison of Functional Outcome Between BQT and SBHT ACL Reconstruction
ACL rupture has a high morbidity in productive-age population. The increasing incidence and proper management has become a point of interest in the musculoskeletal sport injury.
- Trial name
- BQTSBHTFMUI (NCT04536246)
- Testing
- Bone Quadriceps Tendon (BQT) arthroscopic-assisted ACL reconstruction, Single-Bundle Hamstring Tendon (SBHT) arthroscopic-assisted ACL reconstruction
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Lateral Epicondylitis
Neuromodulation in Lateral Elbow Pain
Lateral epicondylitis (LE), also known as tennis elbow, refers to a painful condition at or around the lateral epicondyle of the humerus and common extensor tendon (CET) that is aggravated by dorsiflexion and/or supination of the…
- Trial name
- PNM (NCT03433716)
- Testing
- Ultrasound-guided Percutaneous Neuromodulation
- Where
- Spain
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Blanca de la Cruz Torres
Rotator Cuff Tear
Impact of Postoperative Management on Outcomes and Healing of Rotator Cuff Repairs
Rotator cuff tears are seen in 40% of subjects over age 50 57, with a prevalence known to increase with each decade of life 51. Each year rotator cuff disorders lead to 4.5 million physician visits, 40,000 inpatient surgeries…
- Trial name
- NCT01383239
- Testing
- Immediate Postoperative Therapy, Delayed Physical Therapy
- Where
- 9 sites in United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Shoulder Pain, Rotator Cuff Injuries
Investigation of the Effects of Kettlebell Training
Kettlebell exercises are seen as one of the approaches that can be used conservatively in individuals with shoulder pain. However, it is still unknown what results it has on its therapeutic effects.
- Trial name
- NCT07289893
- Testing
- Kettlebell Exercise, Standard Exercise
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Chronic Lateral Epicondylosis
PEAK Platelet Rich Plasma Injection Treatment for Chronic Lateral Epicondylosis
The proposed project will be the first to assess pain- and function-dependent, elbow-specific quality of life and in-vivo mechanical properties of common extensor tendons post-treatment with PRP in a Level 1, RCT with subject and…
- Trial name
- NCT03072381
- Testing
- Platelet Rich Plasma - Group 1, Corticosteroid Control - Group 2
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Rotator Cuff Injuries
Frequency Analysis of the Ultrasound Images in Rotator Cuff Tendon
Previous studies used spatial frequency analysis of tendon ultrasound images and considered that the parameters can reflect the micro-structure of the tendon.
- Trial name
- NCT04859413
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Tennis Elbow
Comparison of the Effect of a Non-immersive VRE and CT in Patients With Tennis Elbow
This study investigates the comparative effectiveness of non-immersive virtual reality (VR) therapy and conventional physiotherapy in managing tennis elbow (lateral epicondylitis).
- Trial name
- NCT06739837
- Testing
- traditional physiotherapy, Non-immersive VR therapy
- Where
- Pakistan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Superior University
Trigger Finger
Endoscopic Trigger Finger Release
The purpose of this study is to compare recovery, scar, and patient satisfaction after retrograde endoscopic trigger finger release versus the standard open surgical treatment.
- Trial name
- NCT03883477
- Testing
- Endoscopic Release, Standard Open Release
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center